Safe Implementation of Treatments in Stroke: a study on intravenous thrombolysis in patients over 80 years of age with acute ischaemic stroke by Manju Krishnan, Danilo Toni, Niaz Ahmed, Anand Dixit, Ana Paiva Nunes, Marius Matusevicius, Jose Egido, Letizia Concari, Monica Reggiani, Alain Pagès, Thierry Danays

“…Comparisons will be performed between patients treated post-approval (July 2018 to December 2021) period with those treated pre-approval (June 2015 to June 2018) period using propensity score matching (PSM).Setting This is a multicentre international study in hospitals treating AIS with IVT.Participants Patients aged >80 years who otherwise followed the IVT Summary of Product Characteristics of European countries as part of the mutual recognition procedure.Primary and secondary outcomes The main outcomes were symptomatic intracerebral haemorrhage per SITS monitoring study definition, death and functional independency as defined by a modified Rankin Scale score of 0–2 at 90 days.Results After PSM, 614 patients remained in each group (mean age 87 years, 39% males). …”
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Pirfenidone Alleviates Choroidal Neovascular Fibrosis through TGF-β/Smad Signaling Pathway by Chuang Gao, Xin Cao, Lili Huang, Yueqi Bao, Tao Li, Yue Di, Liucheng Wu, Yu Song

“…The fibrosis area was monitored by staining the collagen type I (Col-I). …”
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The role of eco-digital learning in enhancing the impact of IoT, blockchain, and artificial intelligence on green supply chain for SME internationalization by Faisol, Hestin Sri Widiawati, Risky Aswi Ramadhani, Bambang Agus Sumantri

“…The results indicate that the adoption of the Internet of Things demonstrates a significant positive effect (p = 0.0000, T-statistic = 4.6695), improving real-time monitoring and operational efficiency. Blockchain also positively affects SME internationalization (p-value = 0.0085, T-statistic = 2.6427), enhancing supply chain transparency and ensuring compliance with international standards. …”
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Migrant Health Country Profile tool (MHCP-t) for transforming health data collection and surveillance in the Middle East and North African (MENA) region: tool development protocol... by Farah Seedat, Bouchra Assarag, Kolitha Wickramage, Sally Hargreaves, Ana Requena-Mendez, Dominik Zenner, Anna Deal, Stella Evangelidou, Oumnia Bouaddi, Moudrick Abdellatifi, Hassan Edries, Eman Elafef, Taha Maatoug, Anissa Ouahchi, Sara Arias, Adel Abdelkhalek, Ibrahim Ahmed Bani, Kenza Hassouni, Mahmoud Hilali, Mohamed Khalis, Wejdene Mansour, Ali Mtiraoui, Hassan Chrifi, Mohamed Douagi, Abdedayem Khelifi

“…Yet, because of a lack of epidemiological data, there is an urgent need to strengthen routine data collection around migrant health and to define key indicators towards migrant health monitoring. To address this problem, we aim to design and pilot test the Migrant Health Country Profile tool (MHCP-t) which can collate country-level data collection around migration health data, policies and healthcare provision.Methods and analysis The MHCP-t development is a stepwise process that will integrate a process evaluation model with active involvement and engagement of multilevel stakeholders. …”
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The association of systemic immune-inflammation index with incident breast cancer and all-cause mortality: evidence from a large population-based study by Yu Li, Yu Li, Meng Yu, Ming Yang, Jingqi Yang

“…These findings highlight the importance of monitoring systemic inflammation and suggest that SII could serve as a valuable prognostic tool.…”
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Design of a new model yeast consortium for ecological studies of enological fermentation by Pourcelot, Eléonore, Vigna, Audrey, Marlin, Thérèse, Galeote, Virginie, Nidelet, Thibault

“…By tagging each yeast species with distinct fluorescent markers, the study enables real-time monitoring of individual species within the consortium using flow cytometry. …”
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Eating disorders in weight-related therapy (EDIT): Protocol for a systematic review with individual participant data meta-analysis of eating disorder risk in behavioural weight man... by Hiba Jebeile, Natalie B Lister, Sol Libesman, Kylie E Hunter, Caitlin M McMaster, Brittany J Johnson, Louise A Baur, Susan J Paxton, Sarah P Garnett, Amy L Ahern, Denise E Wilfley, Sarah Maguire, Amanda Sainsbury, Katharine Steinbeck, Lisa Askie, Caroline Braet, Andrew J Hill, Dasha Nicholls, Rebecca A Jones, Genevieve Dammery, Alicia M Grunseit, Kelly Cooper, Theodore K Kyle, Faith A Heeren, Fiona Quigley, Rachel D Barnes, Melanie K Bean, Kristine Beaulieu, Maxine Bonham, Kerri N Boutelle, Braulio Henrique Magnani Branco, Simona Calugi, Michelle I Cardel, Kelly Carpenter, Hoi Lun Cheng, Riccardo Dalle Grave, Yngvild S Danielsen, Marcelo Demarzo, Aimee Dordevic, Dawn M Eichen, Andrea B Goldschmidt, Anja Hilbert, Katrijn Houben, Mara Lofrano do Prado, Corby K Martin, Anne McTiernan, Janell L Mensinger, Carly Pacanowski, Wagner Luiz do Prado, Sofia M Ramalho, Hollie A Raynor, Elizabeth Rieger, Eric Robinson, Vera Salvo, Nancy E Sherwood, Sharon A Simpson, Hanna F Skjakodegard, Evelyn Smith, Stephanie Partridge, Marian Tanofsky-Kraff, Rachael W Taylor, Annelies Van Eyck, Krista A Varady, Alaina P Vidmar, Victoria Whitelock, Jack Yanovski, Anna L Seidler, Eating Disorders In weight-related Therapy (EDIT) Collaboration

“…Identifying participant level risk factors predicting eating disorder risk will inform screening and monitoring protocols to allow early identification and intervention for those at risk.…”
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A perspective on the current state of smartphone-based mobile applications for scar assessment by Peter Moortgat, Jill Meirte, Mieke Anthonissen, Koen Maertens, Thibau Demarbaix, Ulrike Van Daele

“…Scars can have a significant impact on the physical and psychosocial well-being, so the assessment of scars is crucial for accurate diagnosis, monitoring, and treatment. Traditionally, these assessments required specialized, bulky equipment that needed a wired connection to computers, making these assessment tools less accessible and efficient. …”
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The concentration of selected organophosphorus pesticides associated with PM10 in agricultural ambient air in Iran: Health risk assessment using Monte Carlo simulation by Asma Tabanasl, Amin Mohammadpour, Aboozar Soltani, Mohammad Hoseini, Mohammadali Baghapour

“…However, the study underscores the necessity for ongoing monitoring and increased public awareness regarding pesticide exposure.…”
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Association between Corrected QT Interval, QT Dispersion and Clinico-biochemical Severity of Diabetic Ketoacidosis in Children Aged 1-12 Years: A Prospective Cohort Study by Hamritha Ashokkumar, A Suriya, Shreenivas RachakondaPoovazhagi, Shreenivas Rachakonda, Shreenivas Rachakonda

“…Conclusion: The study highlights the QTc prolongation and QTd in children with DKA, which are closely linked to metabolic derangements. Routine ECG monitoring is essential for the early detection of QT prolongation, aiding in the prevention of life-threatening arrhythmias and improving patient outcomes.…”
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Impact of primary care benefits on healthcare utilisation and estimated out-of-pocket expenses in urban, rural and remote settings in the Philippines by Antonio L Dans, Arianna Maever L Amit, Leonila F Dans, Gillian Sandigan, Regine Ynez H De Mesa, Mia P Rey, Josephine T Sanchez, Cara Lois T Galingana, Nannette Bernal-Sundiang, Maria Rhodora N Aquino, Johanna Faye E Lopez, Janelle Micaela S Panganiban, Romelei Camiling-Alfonso, Jose Rafael A Marfori, Ramon Pedro Paterno, Carol Stephanie Chua Tan-Lim, Noleen Marie Fabian, Chad Lester Lastrilla, Miguel Callo

“…In this study, two key outcomes were monitored: (1) monthly healthcare utilisation measured by the total number of outpatient consultations per site and (2) change in OOP expenses from baseline to endline within a 1 year study period.Results All sites had a positive trend in monthly outpatient consultations in healthcare utilisation over 1 year. …”
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The Impact of Fireworks on Selected Ambient Particulate Metal Concentrations Associated with the Independence Day Holiday by Danielle Rocco, Esther Morales, Tyler Deflin, Jason Truong, Jaebin Ju, Daniel B. Curtis

“…Hourly ambient particulate concentrations at a nearby monitoring station exceeded 500 μg m⁻³ and 300 μg m⁻³ in 2020 and 2021, respectively. …”
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Association between fasting blood glucose and psychotic symptoms in Chinese patients with first-episode drug-naïve major depressive disorder by Xingzhi Xia, Hanxu Deng, Wei Ren, Lin Yang, Yingzhao Zhu, Yaozhi Liu, Junjun Liu, Xueli Zhao, Fengnan Jia, Xiangdong Du, Xiangyang Zhang

“…A variety of neurotransmitters, hormones and corresponding receptors in the endocrine system are involved in the onset and progression of depression, and fasting blood glucose (FBG) can be an important indicator for monitoring the stability of the endocrine system. The aim of this study was to investigate the relationship between FBG and PD in a Chinese population with first-episode drug-naïve (FEDN) major depressive disorder (MDD). …”
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Maternal neonicotinoid pesticide exposure impairs glucose metabolism by deteriorating brown fat thermogenesis by Wenwen Zhu, Jiali Fang, Chenbo Ji, Hong Zhong, Tianying Zhong, Xianwei Cui

“…Urinary concentrations of seven widely used NEOs were quantified using ultra-high performance liquid chromatography multiple reaction monitoring mass spectrometry (UHPLC-MRM-MS/MS). Correlation analysis revealed the associations between NEOs concentrations and glucose homeostasis parameters. …”
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Effectiveness of the ARTHE-e app for exercise adherence in people with knee osteoarthritis: protocol for a randomised controlled trial by Bruno Pereira, Charlotte Lanhers, Emmanuel Coudeyre, Lech Dobija, Mathilde Pelletier-Visa, Alexis Bonhomme

“…The participants will undergo a comprehensive assessment, including the Exercise Adherence Rating Scale (EARS) at 2, 4 and 6 months, Knee Injury and Osteoarthritis Outcome Score, Evaluation of the Perception of Physical Activity, Tampa Scale of Kinesiophobia, European Quality of Life 5 Dimensions and 3 Lines and a Visual Analogue Scale rating of pain at baseline and 6 months. Adherence will be monitored using a connected bracelet. The intervention group will use the ARTH-e application for 6 months, while the control group will follow stay-active advice from their physician. …”
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Study protocol for a randomised controlled trial of a care partner assisted intervention to improve oral health of individuals with mild dementia by Bei Wu, Gary Yu, Brenda L Plassman, Patricia Poole, Shahrzad Siamdoust, Melanie Bunn, Bobbi Burwell, Yaolin Pei, Christine Downey, Danni Gomes, Angela Kamer, A Leak Bryant, Ruth A Anderson

“…The study enrollment started in November 2021, and the data collection will end in Spring 2024.Ethics and dissemination The study has been approved by the Institutional Review Board of the NYU Grossman School of Medicine and Duke University, and is registered at Clinicaltrials.gov. A Data Safety Monitoring Board has been constituted. The study findings will be disseminated via peer-reviewed publications, conference presentations and social media.Trial registration number NCT04390750.…”
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Clinical characteristics of EGFR-ctDNA shedders in EGFR-mutant NSCLC patients by Martina Ruglioni, Iacopo Petrini, Stefania Crucitta, Andrea Sbrana, Giovanna Irene Luculli, Leila Sadeghi Gol, Carola Forte, Antonio Chella, Christian Rolfo, Romano Danesi, Marzia Del Re

“…Methods: Blood samples were collected from patients with stage IV EGFR-mutated (mEGFR) NSCLC before treatment and monitored until disease progression. EGFR was assessed on tissue by standard procedures, while EGFR status on ctDNA was tested using dPCR at baseline and at the first reassessment. …”
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Effect of video-based trauma-informed care training for nursing staff on seclusion and restraint of psychiatric inpatients: A non-randomized controlled study by Michi Miyake, Megumi Hazumi, Kentaro Usuda, Takahiro Kawashima, Maiko Fukasawa, Hisateru Tachimori, Daisuke Nishi

“…Data were collected using a specialized psychiatric monitoring system from April 2020 to October 2021 pre-intervention and from February 2022 to January 2023 post-intervention. …”
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Patterns of psychiatric healthcare use during pandemic times among boys and girls with pre-existing diagnoses: a Norwegian nationwide primary and specialist healthcare registry stu... by Ingunn Olea Lund, Pia Jensen, Christian Madsen, Lars Johan Hauge, Alexandra Havdahl, Anne Reneflot, Ragnhild Brandlistuen, Helga Ask

“…The study underscores the importance of continuous monitoring and support for this group, ensuring accessible and responsive healthcare during public health emergencies.…”
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An Enhanced Three-Band Algorithm for Retrieving Phycocyanin Concentration from Satellite Data in Plateau Inland Lake by Dajun Yuan, Bo-Hui Tang, Dong Wang, Junyi Chen, Zhen Zhang, Zhitao Fu

“…Therefore, the introduction of the ETBA has a direct positive impact on monitoring harmful algal blooms caused by cyanobacteria in inland and coastal water.…”
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