Clozapine for Treatment-Resistant Disruptive Behaviors in Youths With Autism Spectrum Disorder Aged 10-17 Years: Protocol for an Open-Label Trial by André Luiz Schuh Teixeira da Rosa, Marina Ribeiro Barreto da Costa, Gabriela Bezerra Sorato, Felipe de Moura Manjabosco, Érica Bonganhi de Bem, Lucas Dellazari, Arthur Bezerra Falcão, Lucas de Oliveira Cia, Olivia Sorato Bezerra, Rogério Boff Borges, Luis Augusto Rohde, Ana Soledade Graeff-Martins

“…Standardized instruments were applied before, during, and after the treatment, and rigorous clinical monitoring was performed weekly. The primary outcome was assessed using the Irritability Subscale of the Aberrant Behavior Checklist. …”
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SO₂ emissions derived from TROPOMI observations over India using a flux-divergence method with variable lifetimes by Y. Chen, Y. Chen, R. J. van der A, J. Ding, H. Eskes, J. E. Williams, N. Theys, A. Tsikerdekis, P. F. Levelt, P. F. Levelt, P. F. Levelt

“…We present a monthly SO<span class="inline-formula">₂</span> emission inventory for India covering December 2018 to November 2023 based on the Tropospheric Monitoring Instrument (TROPOMI) Level-2 COBRA SO<span class="inline-formula">₂</span> dataset, using an improved flux-divergence method and estimated local SO<span class="inline-formula">₂</span> lifetime, which includes both its chemical loss and dry deposition. …”
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Alterations in physicochemical parameters of water and the growth performance of juvenile beluga Huso huso in earthen ponds by Hashem Noferesti, Hojatollah Jafaryan, Rahman Patimar, Hossein Adineh

“…However, the highest condition factor (0.94 ± 1.11) was measured during the second sampling period (p<0.05).Conclusion: The results indicated that precise water quality management and continuous monitoring of its parameters, especially in sturgeon farming, are essential and can help improve growth conditions and reduce mortality rates. …”
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Transurethral Water Vapor Ablation: Potential for a Novel Prostate Cancer Management Strategy by Warlick CA, Spilseth BD, Dixon CM

“…Currently, many men with low-risk disease are offered active surveillance, during which the prostate cancer is closely monitored for any changes, whereas men with intermediate or high-risk localized cancers are more often considered for surgical removal of the prostate or treatment with radiation. …”
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Adapting a Mobile Health App for Smoking Cessation in Black Adults With Anxiety Through an Analysis of the Mobile Anxiety Sensitivity Program Proof-of-Concept Trial: Qualitative St... by Marshall K Cheney, Adam C Alexander, Lorra Garey, Matthew W Gallagher, Emily T Hébert, Anka A Vujanovic, Krista M Kezbers, Cameron T Matoska, Michael J Zvolensky, Michael S Businelle

“…Suggested improvements included opportunities to engage with other participants, more control over app functions, and additional self-monitoring functions. ConclusionsAdding culturally tailored material to an evidence-based mobile health (mHealth) intervention could increase the use of smoking cessation interventions among Black adults who want to quit smoking. …”
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A FAIR and open geographic data collection for the Massaciuccoli Lake basin wetland in ItalyZenodoZenodo by Gian Luca Vannini, Pasquale Bove, Gianpaolo Coro

“…Future projections are available under the Representative Concentration Pathways (RPC) 2.6, 4.5, and 8.5 to simulate low, medium, and high greenhouse gas concentration scenarios respectively.The present geodata collection is particularly useful for wetland monitoring, management and planning. It can easily be integrated with ecological models and predictive studies to analyse the effects of climate change and anthropogenic pressures on wetlands. …”
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Functional cognitive disorder: Beyond pseudodementia by D.S. Marín-Medina, P.A. Arenas-Vargas, M. del Pilar Velásquez-Duque, P.M. Bagnati

“…We also explore the mechanisms that could explain this condition, which include metacognitive errors, excessive self-monitoring, and abnormal emotional processing, among others. …”
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An Arctic sea ice concentration data record on a 6.25&thinsp;km polar stereographic grid from 3 years of Landsat-8 imagery by H.-S. Jung, S.-M. Lee, S.-M. Lee, J.-H. Kim, K. Lee

“…The coverage of Arctic sea ice (i.e. sea ice concentration (SIC)) has been monitored since 1972 using satellite passive microwave (PMW) measurements because of their extensive coverage and all-weather capability. …”
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Preoperative ultrasound risk factors for peripartum hysterectomy among PAS suspected pregnancies by Lulu Wang, Tianjiao Liu, Yang Yang, Yalan Li, Li Xiao, Xin Li, Sumei Wei

“…Cesarean deliveries, placental positioning on the anterior uterine wall, GHD, types of PAS, and ultrasound PAS score higher than 10 predicts peripartum hysterectomy, highlighting the importance of early, timely, and consistent monitoring of the placenta using obstetric ultrasound in pregnancies with suspected PAS. …”
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The influence of exercise modality and intensity on ventricular arrhythmia burden and perception of effort in patients with Arrhythmogenic Right Ventricular Cardiomyopathy with pla... by Fernando G. Beltrami, Kyle G. P. J. M. Boyle, Guan Fu, Corinna Brunckhorst, Firat Duru, Christina M. Spengler, Ardan M. Saguner

“…Methods Twenty ARVC patients (8 f/12 m, age 48 ± 15 years, BMI 24 ± 3 kg/m2, resting PVC burden 4 ± 4%) with a heterozygous pathogenic/likely pathogenic plakophilin-2 (PKP-2) variant prospectively performed different exercises while monitored via 12-lead ECG. The order of modalities was randomized and participants were instructed to stop when surpassing perceived exertion of 15 (6-20 Borg scale). …”
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Convolutional neural networks for sea surface data assimilation in operational ocean models: test case in the Gulf of Mexico by O. Zavala-Romero, O. Zavala-Romero, A. Bozec, E. P. Chassignet, J. R. Miranda, J. R. Miranda

“…These insights pave the way for faster, more reliable ocean models, benefiting environmental monitoring and maritime operations.</p>…”
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Incidence, Risk Factors, and Outcomes of Perioperative Atrial Fibrillation following Noncardiothoracic Surgery: A Systematic Review and Meta-Regression Analysis of Observational St... by Yamini Subramani, Omar El Tohamy, Daniil Jalali, Mahesh Nagappa, Homer Yang, Ashraf Fayad

“…The atrial fibrillation group was at increased odds for postoperative cardiac complications, stroke, and higher mortality, emphasizing the need for risk stratification and close monitoring.…”
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Multi-spatial urban function modeling: A multi-modal deep network approach for transfer and multi-task learning by Zhaoya Gong, Chenglong Wang, Bin Liu, Binbo Li, Wei Tu, Yuting Chen, Zhicheng Deng, Pengjun Zhao

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Population structure, floral diversity, habitat geography, and conservation status of Himalayan horse chestnut (Aesculus indica) in western Himalayan moist temperate forest ecosyst... by Urwa Irfan, Hamayun Shaheen, Muhammad Manzoor, Muhammad Manzoor, Sidra Nasar, Raja Waqar Ahmed Khan, Syed Waseem Gillani, Syed Waseem Gillani, Abdulwahed Fahad Alrefaei, Arbaz Attique, Asif Kamal, Sarah Abdul Razak, Malik Talha Riaz

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Examining the impact of a community-based exercise intervention on cardiorespiratory fitness, cardiovascular health, strength, flexibility and physical activity among adults living... by Kelly K O'Brien, Aileen M Davis, Soo Chan Carusone, Lisa Avery, Ada Tang, Patricia Solomon, Rachel Aubry, Mehdi Zobeiry, Ivan Ilic, Zoran Pandovski, Ahmed M Bayoumi

“…Phase 1 included baseline monitoring (8 months); Phase 2 included the CBE Intervention (6 months): participants were asked to exercise (aerobic, strength, balance and flexibility training) for 90 minutes, 3 times/week, with weekly supervised coaching at a community-based fitness centre; and Phase 3 included follow-up (8 months) where participants were expected to continue with thrice weekly exercise independently. …”
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A comprehensive, population level evaluation of previously reported drug triggers of pemphigus highlights immunomodulatory capacity as a common characteristic by Justin Baroukhian, Kristina Seiffert-Sinha, Animesh A. Sinha

“…FindingsIn this series of observational, retrospective, case-control, pharmacovigilance analyses of the FDA Adverse Event Reporting System, the odds of reporting the adverse event pemphigus were significantly elevated among individuals exposed to 11/36 previously reported trigger drugs namely, gold sodium thiomalate, penicillamine, piroxicam, rifampin, hydroxychloroquine, imiquimod, hydrochlorothiazide, irbesartan, lisinopril, nivolumab, and nifedipine.MeaningEnvironmental exposures such as drugs are relevant players in the pathogenesis of autoimmune diseases and clinicians who treat patients with autoimmune blistering diseases such as pemphigus should consider performing a detailed medication history leveraging this information regarding deleterious drug-disease interactions at initial evaluation as well as longitudinal monitoring of patients to better inform clinical care decisions.ImportancePemphigus vulgaris (PV) is a rare, potentially fatal autoimmune disease with pathogenic contributions from both genetic as well as environmental factors, notably drug exposures. …”
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Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes by Kazuhiro Kakimi, Hirokazu Matsushita, Masaaki Komatsu, Eiryo Kawakami, Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa, Keita Koseki, Eiji Warabi, Tomoyuki Ohue, Katsuyuki Shiroguchi, Heiichiro Udono

“…In addition, conditional knockout mice for Nrf2 and p62 were used to detect these markers, together with the monitoring of in vivo tumor growth. RNA sequencing was performed for CD8TILs and tumor cells. …”
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Identification and Classification of Factors Influencing the Regulation of Priority Goods Markets Based on Network Governance with an Interpretive Structural Modeling Approach by sadegh Dadashi, Fattah Sharifzadeh, Reza Vaezi, Hossein Aslipour

“…Policy cycles within the market regulation network should facilitate a clear division of labor, implementation, and rigorous monitoring at both national and provincial levels. Lastly, network management should focus on transparency and accountability among all actors. …”
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BCL-2 overexpression exosomes promote the proliferation and migration of mesenchymal stem cells in hypoxic environment for skin injury in rats by Ying Wang, Guang Li, Guofeng Li, Yutao Pan, Zhongmin Liu

“…Cell proliferation ability was monitored by cell proliferation test. Cell migration test was used to check the migration capacity of MSCs. …”
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Determining nutritional indices of Dori bleak, Alburnus doriae and Brond Snout, Chondrostoma regium in Zayandehroud River, Central Iran by Omidvar Farhadian, JAVAD BAGHERI, Nasrollah Mahboobi Soofiani, Safiollah Heidari, Eisa Ebrahimi

“…Conclusion: The results demonstrated that A. doriae and C. regium are carnivorous and omnivorous, respectively. A. doriae prefers insects, but C. regium consumes mostly insects and filamentous algae as the preferred food. …”
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