Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOk... by Narayanaswamy Venketasubramanian, Deidre Anne De Silva, Christopher P L H Chen, Cyrus G Escabillas, John Harold Hiyadan, Johnny K Lokin, Romulo U Esagunde, Joel M Advincula, Christian Oliver C Co, Maria Epifania V Collantes, Annabelle Y Lao, Yeow-Hoay Koh, Carol Huilian Tham

“…An independent Data Monitoring Committee oversees patient safety.Outcomes The primary outcome is mean change from baseline in FMA total score at 24 weeks. …”
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The Wayqecha Amazon Cloud Curtain Ecosystem Experiment: A new experimental method to manipulate fog water inputs in terrestrial systems by Daniel B. Metcalfe, Darcy F. Galiano Cabrera, Luis Miguel Alvarez Mayorga, Roxana Sacatuma Cruz, Daniela Corrales Alvarez, Blanca Rosa Espinoza Otazu, Walter Huaraca Huasco, Jimmy R. Chambi, Maria E. Ezquerra, Beisit L. Puma Vilca, Mark Mulligan, Matthew A. Vadeboncoeur, Heidi Asbjornsen, Paulo R. L. Bittencourt, Aline B. Horwath, David C. Bartholomew

“…The curtains divert and intercept airborne water droplets in fog moving upslope, thereby depriving a ~420 m2 patch of forest immediately behind the curtains of this water source. We monitored inside the treatment and a nearby unmodified control plot various metrics of water availability (air humidity, vapour pressure deficit, leaf wetness and soil moisture) and other potentially confounding variables (radiation, air and soil temperature) above and below the forest canopy. …”
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The Efficacy and Safety of the Chinese Herbal Formula, JTTZ, for the Treatment of Type 2 Diabetes with Obesity and Hyperlipidemia: A Multicenter Randomized, Positive-Controlled, Op... by Xiaotong Yu, Lipeng Xu, Qiang Zhou, Shengping Wu, Jiaxing Tian, Chunli Piao, Hailong Guo, Jun Zhang, Liping Li, Shentao Wu, Meizhen Guo, Yuzhi Hong, Weirong Pu, Xiyan Zhao, Yang Liu, Bing Pang, Zhiping Peng, Song Wang, Fengmei Lian, Xiaolin Tong

“…Adverse reactions and hypoglycemia were monitored. Results. HbA1c decreased by 0.75 ± 1.32% and 0.71 ± 1.2% in the JTTZ and MET groups, respectively, after 12 weeks of treatment. …”
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Study protocol of a pilot randomised controlled trial assessing the feasibility and acceptability of RecoverEsupport: a digital health intervention to enhance recovery in women und... by Christopher Oldmeadow, Mitch J Duncan, Penny Reeves, Priscilla Viana da Silva, Rebecca Wyse, Helen Moore, Alison Zucca, Sancha Robinson, Stephen Ridley Smith, Emma Sansalone, Owen Morris, Rebecca Chenery, Lara Riley, Anna Palazzi-Parsons

“…The DHI incorporates the following evidence-based behaviour change strategies: education, self-monitoring and feedback and prompts and cues. The primary trial aims are to assess the feasibility of the trial and the acceptability of the RecoverEsupport intervention. …”
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Peri‐ictal yawning: A potential lateralizing sign in temporal lobe epilepsy by Xiaoping Du, Yi Yao, Jiani Chen, Xiaoping Yang, Lei Zhang, Yingying Tang, Xiaoting Hao, Dong Zhou, Shizhong Lian, Fengpeng Wang, Xiaobin Zhang, Meizhen Sun, Junhong Guo

“…Methods Among 236 consecutive TLE patients admitted for video‐EEG monitoring, we analyzed the clinical characteristics, along with scalp video‐EEG, magnetic resonance imaging (MRI), fluorodeoxyglucose‐positron emission tomography (FDG‐PET), Wada test, and stereo EEG (SEEG) in patients with PY. …”
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High-dependency unit care after carotid endarterectomy for asymptomatic stenosis by Beatriz Guimarães, Andreia Coelho, Marina Dias-Neto, Ricardo Castro-Ferreira, João Peixoto, Luís Fernandes, Roberto Boal, Marta Machado, Francisco Basílio, Patrícia Carvalho, Armando Mansilha, Alexandra Canedo

“… INTRODUCTION: Asymptomatic patients benefit from 3 to 6 hours of neurological and invasive blood pressure (BP) monitoring following carotid endarterectomy (CEA). Only a minority of patients will benefit from a prolonged stay in a high-dependency unit (HDU). …”
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Qualitative evaluation of the Rehabilitation Exercise and psycholoGical support After COVID-19 InfectioN (REGAIN) randomised controlled trial (RCT): ‘you are not alone’ by Gordon McGregor, Susanne Finnegan, Martin Underwood, Joyce Yeung, James Mason, Peter Heine, Nigel Edwards, Julie Bruce, Kate Seers, Harbinder Kaur Sandhu, Helen Atherton, Sharisse Alleyne, Katie Booth, Ranjit Lall, Vivien P Nichols, Stuart Ennis, Scott McGuire, Rachel Potter, Jessica Smith, Chen Ji, Shilpa Patel, Henry Nwankwo, Kate Evans, Susie Hennings, Alastair Canaway, Grace Lobley, David Mcwilliams, Christina Jones, Emma Padfield, David Montgomery, Beatriz Lara, Becky Haley, Francesca Denton, Bartholomew Sheehan, Mariam Ratna, Elaine Fairbrother, Zoe Noakes, Bogdan Zutic, Lee Austin, Tom Forsyth, Anne Bush, Alan Bush, Patrick Sawdon, Jonathon Prosser, Lee Tompkins, Jonathon Guck, Danielle Hale, Juwairia Said, Georgie Ray, Rowena Williams, Gail Evans, Thillini Hettiarachchi, Abeesh Panicker

“…The themes from group exercise were: (1) monitoring and modification of the online exercise; (2) catering for differing abilities; (3) feeling safe and confident to exercise; (4) progression of fitness; (5) optimal timing in the recovery trajectory; (6) group effect; (7) initial apprehension about exercise group; (8) gauging exercise capabilities; (9) translating exercises into life; and (10) on-demand supplementary videos. …”
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The first application of flush probe arrays on HL-3 tokamak by Z.H. Huang, L.W. Yan, K.Y. Yi, Na Wu, W.J. Chen, W.C. Wang, Yu He, J. Chen, J. Cheng, W. Zhao, J.M. Gao, L. Nie, Z.B. Shi, X.Q. Ji, W.L. Zhong

“…Moreover, the discharge monitoring and mode conversion between the triple and single probes could be freely performed via a remote-control workstation. …”
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Antimicrobial Resistance and Biofilm-Forming Ability in ESBL-Producing and Non-ESBL-Producing <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> Isolated from Canine Urinary... by Alessia Facchin, Joel Filipe, Irene Mauri, Filippo Tagliasacchi, Guido Grilli, Tiziana Vitiello, Gabriele Ratti, Laura Musa, Martina Penati, Paola Scarpa, Stefania Lauzi

“…The association of moderate biofilm production with MDR highlights the need for monitoring and surveillance of bacterial prevalence and resistance patterns of urinary isolates in dogs.…”
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Tear glucose is associated with the presence and severity of diabetic retinopathy by Ningyao Cao, Lili Feng, Wei Xu, Fanglin He, Caiwen Xiao, Yan Liu, Weirong Xu, Jingjing Cui, Yuqian Guo, Lianqing Yao, Wenwen Xia, Fei Chen, Yong Li, Chuandi Zhou, Xiaofang Xu

“…TG might be an easy-to-use, non-invasive parameter to the screening and monitoring of DR among patients with diabetes.…”
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Antiganglioside Antibodies and Inflammatory Response in Cutaneous Melanoma by Corina Daniela Ene, Mircea Tampa, Ilinca Nicolae, Cristina Iulia Mitran, Madalina Irina Mitran, Clara Matei, Ana Caruntu, Constantin Caruntu, Simona Roxana Georgescu

“…Antiganglioside antibodies associated with inflammation markers could be used as diagnostic, monitoring, and treatment tools in patients with cutaneous melanoma.…”
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Nucleotide receptor P2X7/STAT6 pathway regulates macrophage M2 polarization and its application in CAR-T immunotherapy by Qin Si, Lu Yang, Jie Liu, Hui Liu, Ruifang Bu, Na Cui

“…Additionally, the phosphorylation level of STAT6 was monitored by western blot. We engineered CAR-T cells targeting the non-functional P2X7 (nfP2X7) receptor, and co-cultured them with macrophages silencing P2X7 receptor along with OC cells. …”
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Ecological impacts of single-axis photovoltaic solar energy with periodic mowing on microclimate and vegetation by Yudi Li, Yudi Li, Alona Armstrong, Alona Armstrong, Christopher Simmons, Noah Z. Krasner, Noah Z. Krasner, Rebecca R. Hernandez, Rebecca R. Hernandez, Rebecca R. Hernandez, Rebecca R. Hernandez

“…Over a 12-month period, we monitored nine above- and belowground microclimate variables and 16 plant ecology metrics across these micro-patches. …”
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Estimation Model for Cotton Canopy Structure Parameters Based on Spectral Vegetation Index by Yaqin Qi, Xi Chen, Zhengchao Chen, Xin Zhang, Congju Shen, Yan Chen, Yuanying Peng, Bing Chen, Qiong Wang, Taijie Liu, Hao Zhang

“…By integrating spectral analysis techniques with remote sensing, this research offers valuable insights for precision cotton planting and field management, enabling optimized agricultural practices and enhanced vegetation health monitoring.…”
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Assessment of photoreceptor recovery and visual function utilizing adaptive optics and microperimetry in patients with surgically closed macular holes by Yuanyuan Liu, Xueli Yang, Wei Zhou, Jinguo Yu, Song Chen, Tiangeng He, Caiyun You, Xiangda Meng, Mengyu Liao, Yi Lei, Hua Yan

“…Visual and structural outcomes were monitored 3 months to 2 years postoperatively: best-corrected visual acuity (BCVA), MH diameter and duration, optical coherence tomography (OCT) images, 4° retinal mean sensitivity (RMS), fixation rates, 68.2 % BCEA (binary contour ellipse area) of microperimetry, and cone density as measured by AOSLO. …”
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Computational pathology assessments of cardiac stromal remodeling: Clinical correlates and prognostic implications in heart transplantation by Eliot G. Peyster, MD, MSc, Cai Yuan, PhD, Sara Arabyarmohammadi, PhD, Priti Lal, MD, Michael D. Feldman, MD, PhD, Pingfu Fu, PhD, Kenneth B. Margulies, MD, MS, Anant Madabhushi, PhD, FAIMBE, FIEEE, FNAI

“…Both overt and indolent inflammatory insults propel this remodeling, but there is a paucity of tools for monitoring the speed and severity of remodeling over time. …”
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Retrospective, Non-Interventional, Multicenter Study on the Effectiveness and Safety of Intravesical Bacillus Calmette–Guerin in Patients with Non-Muscle-Invasive Bladder Cancer: R... by Panagiotis Angelopoulos, Titos Markopoulos, Lazaros Lazarou, Andreas Skolarikos, Panagiotis Stamatakos, Georgios I. Papadopoulos, Charalampos Fragkoulis, Konstantinos Ntoumas, Napoleon Moulavasilis, Panagiotis Levis, Dimitrios Papanikolaou, Ioannis Sokolakis, Konstantinos Hatzimouratidis, Charalampos Tzanetakos, Marina Psarra, George Mavridoglou, Konstantinos Skriapas, Dimitra Akrivou, Dimitrios Karagiannis, Christos Noutsos, Andreas Georgiou, Konstantinos Hastazeris, George Gourzoulidis, Dionysios Mitropoulos

“…Tumor recurrence and progression were monitored at scheduled time intervals. Primary outcomes included recurrence-free survival (RFS) and progression-free survival (PFS), while adverse events (AEs) constituted secondary outcomes. …”
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Chronic kidney disease progression in patients with previous type 2 diabetes and/or hypertension: a population-based cohort study from primary care in Spain by David Vizcaya, Betlem Salvador-González, Oriol Cunillera-Puértolas, Sílvia Cobo-Guerrero, José Romano-Sánchez, Daniel Bundó-Luque, Ariadna Arbiol-Roca

“…Efforts to slow CKD progression should target both patients with hypertension and T2D, focusing on the identification, close monitoring and effective management of albuminuria and reduced eGFR.…”
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High prevalence of multidrug resistant and extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolated from urinary tract infections in the West reg... by Solomon Bayaba, Raspail Carrel Founou, Flaurant Thibau Tchouangueu, Brice Davy Dimani, Lethicia Danaëlle Mafo, Omer Aurelle Nkengkana, Luria Leslie Founou, Michel Noubom

“…The study emphasizes the necessity of routine screening and monitoring of antimicrobial resistance in healthcare facilities and community settings. …”
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Open-label dose-extending placebos for opioid use disorder: a protocol for a randomised controlled clinical trial with methadone treatment by Annabelle M Belcher, Thomas O Cole, Aaron D Greenblatt, Stephen W Hoag, David H Epstein, Michael Wagner, Amy S Billing, Ebonie Massey, Kristen R Hamilton, Zofia K Kozak, Christopher J Welsh, Eric Weintraub, Emerson M Wickwire, Eric D Wish, Ted J Kaptchuk, Luana Colloca

“…Additionally, the study protocol is reviewed annually by an independent Data and Safety Monitoring Board. Study results will be disseminated via research conference presentations and peer-reviewed publications.Trial registration number NCT02941809.…”
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