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    Unveiling lives: A glimpse into the daily routines of individuals affected by leprosy in Malaysia using the walk-and-talk technique by Norana Abdul Rahman, Vaikunthan Rajaratnam, Ruth M. H. Peters, Mohamed Rusli Abdullah, Karen Morgan

    Published 2025-12-01
    “…Visual, auditory, and field data were transcribed and thematically analysed using NVivo 12, revealing key themes, including resilience and perseverance, employment and economic sustenance, stigma, family support, and community engagement. …”
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    HRS-4642 combined with nimotuzumab in the treatment of recurrent or metastatic pancreatic ductal adenocarcinoma: study protocol of a single-arm, prospective phase Ib/II trial by Qingqing Leng, Jitao Zhou, Xin Wang, Pei Zhang, Huanji Xu, Dan Cao

    Published 2025-07-01
    “…Combining KRAS and EGFR inhibitors has shown clinical efficacy in select solid tumors.ObjectivesTo assess the safety and efficacy of HRS-4642 (KRAS G12D inhibitor) plus nimotuzumab (EGFR inhibitor) in patients harboring the KRAS G12D mutation, recurrent/metastatic PDAC refractory to standard systemic therapy.DesignThis is an open-label, single-center, exploratory clinical trial.MethodsThis study will enroll patients with histologically or cytologically confirmed recurrent or metastatic PDAC harboring the KRAS G12D mutation, who have documented disease progression or intolerance to first-line systemic therapy. …”
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