Divergent alkynylative difunctionalization of amide bonds through C–O deoxygenation versus C–N deamination by Feng Liu, Xueyuan Yan, Fangfang Cai, Wenjuan Hou, Jianyu Dong, Shuang-Feng Yin, Genping Huang, Tieqiao Chen, Michal Szostak, Yongbo Zhou

“…Abstract The transformation and utilization of amides are significant in organic synthesis and drug discovery. Here we demonstrate a divergent alkynylative difunctionalization of amides in a single transformation. …”
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Extensive paralogism in the environmental pangenome: a key factor in the ecological success of natural SAR11 populations by Carmen Molina-Pardines, Jose M. Haro-Moreno, Francisco Rodriguez-Valera, Mario López-Pérez

“…Each variable region was associated with a specific set of genes that, despite exhibiting some divergence, maintained equivalent biological functionality within the population. …”
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Within-species variation in the gut microbiome of medaka (Oryzias latipes) is driven by the interaction of light intensity and genetic background by Evangelista, Charlotte, Kamenova, Stefaniya, Diaz Pauli, Beatriz, Sandkjenn, Joakim, Vøllestad, Leif Asbjørn, Edeline, Eric, Trosvik, Pål, de Muinck, Eric Jacques

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Hybrid azole-based conjugates as upcoming anticancer and antimicrobial agents by Luís M. T. Frija, Bruno E. C. Guerreiro, Inês C. C. Costa, Vera M. S. Isca, Lucília Saraiva, Beatriz G. Neves, Mariana Magalhães, Célia Cabral, Maria L. S. Cristiano, Patrícia Rijo

“…Aim: This study discloses the synthesis and the antimicrobial and anticancer activities of four molecules of structural basis saccharin-thiadiazolyl (4), saccharin-pyridyl (6, 8), and tetrazole-thiadiazolyl (11). …”
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