Promoting Osteogenic Differentiation of Human Adipose-Derived Stem Cells by Altering the Expression of Exosomal miRNA by Shude Yang, Shu Guo, Shuang Tong, Xu Sun

“…Human adipose-derived stem cells (ADSCs) can release exosomes; however, their specific functions remain elusive. …”
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Identification of biomarkers associated with proliferation and differentiation of mesenchymal stem cells in pulmonary adenocarcinoma and establishment of prognostic models by Xin-Xin Zeng, Ke-Xin Xian, Jie-Lun Wen, Qi-Zhe Wang, Xin-Yu Wang, Li-Yue Sun

“…Conclusion In this study, four key biomarkers closely related to mesenchymal stem cell proliferation/differentiation (MSCPD) were identified in lung adenocarcinoma (LUAD), namely MS4A2, IGSF10, NTRK3, and MFAP3L. …”
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Research progress on the effects and mechanisms of traditional Chinese medicine on the proliferation, differentiation, and migration of neural stem cells by WAN Feng, SI Yinchu

“…Traditional Chinese medicine regulates and improves the microenvironment of nerve regeneration by promoting the proliferation and differentiation of neural stem cells, thus promoting the regeneration, repair, and reconstruction functions after nerve injury. …”
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Chlorinated perfluoroalkyl ether sulfonate impairs proliferation and differentiation of neural stem cells via oxidative stress by Yaxin HAN, Longfei FENG, Zhijun ZHOU, Xiuli CHANG

“…Furthermore, the mRNA expression levels of PINK1 and Par after the F-53B exposure were notably reduced (P<0.05).ConclusionF-53B may induce oxidative stress, thereby disrupting mitochondrial morphology and function while inhibiting the PINK1/Parkin-mediated mitophagy pathway, ultimately leading to impaired neural stem cell proliferation and abnormal differentiation. …”
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Long Noncoding RNA H19 Participates in the Regulation of Adipose-Derived Stem Cells Cartilage Differentiation by Hai-lin Pang, Qian-qian Zhao, Yu Ma, Yong-li Song, Jie Min, Jian-rong Lu, Hang Li, Da-qing Zhao

“…ADSCs and bone marrow mesenchymal stem cells (BMSCs) can differentiate into many cell lineages. …”
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Recent Advance in Source, Property, Differentiation, and Applications of Infrapatellar Fat Pad Adipose-Derived Stem Cells by Yu-chen Zhong, Shi-chun Wang, Yin-he Han, Yu Wen

“…This article reviews the anatomy and function of IPFP, as well as the discovery, amplification, multipotential capacity, and application of IPFP-ASCs in order to explain why IPFP-ASC is a superior stem cell source in regenerative medicine.…”
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Atlas of multilineage stem cell differentiation reveals TMEM88 as a developmental regulator of blood pressure by Sophie Shen, Tessa Werner, Samuel W. Lukowski, Stacey Andersen, Yuliangzi Sun, Woo Jun Shim, Dalia Mizikovsky, Sakurako Kobayashi, Jennifer Outhwaite, Han Sheng Chiu, Xiaoli Chen, Gavin Chapman, Ella M. M. A. Martin, Di Xia, Duy Pham, Zezhuo Su, Daniel Kim, Pengyi Yang, Men Chee Tan, Enakshi Sinniah, Qiongyi Zhao, Sumedha Negi, Meredith A. Redd, Joseph E. Powell, Sally L. Dunwoodie, Patrick P. L. Tam, Mikael Bodén, Joshua W. K. Ho, Quan Nguyen, Nathan J. Palpant

“…Abstract Pluripotent stem cells provide a scalable approach to analyse molecular regulation of cell differentiation across developmental lineages. …”
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TRIM32 regulates skeletal muscle stem cell differentiation and is necessary for normal adult muscle regeneration. by Sarah Nicklas, Anthony Otto, Xiaoli Wu, Pamela Miller, Sandra Stelzer, Yefei Wen, Shihuan Kuang, Klaus Wrogemann, Ketan Patel, Hao Ding, Jens C Schwamborn

“…Here we demonstrate for the first time that TRIM32 is expressed in the skeletal muscle stem cell lineage of adult mice, and that in the absence of TRIM32, myogenic differentiation is disrupted. …”
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DNA methylation patterns expose variations in enhancer-chromatin modifications during embryonic stem cell differentiation. by Adi Alajem, Hava Roth, Sofia Ratgauzer, Danny Bavli, Alex Motzik, Shlomtzion Lahav, Itay Peled, Oren Ram

“…By collecting data from the same genomic region, we identified enhancers differentially methylated between these two marks. We observed a global gain of CpG methylation primarily in H3K4me1-marked nucleosomes during mouse embryonic stem cell differentiation. …”
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miRNA changes associated with differentiation of human embryonic stem cells into human retinal ganglion cells by Maryam Esmaeili, Daniel A. Smith, Ben Mead

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Combination of dasatinib and quercetin promotes osteogenic differentiation and stemness maintenance of hPDLSCs via YAP/TAZ by Yunge Qiu, Yajun Zhao, Linglu Jia, Han Xiao, Shaoqing Sun, Weiting Gu, Yong Wen

“…Enhancing the stemness maintenance and osteogenic differentiation potential of hPDLSCs is conducive to their role in periodontal tissue regeneration. …”
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Dynamic and differential regulation of stem cell factor FoxD3 in the neural crest is Encrypted in the genome. by Marcos S Simões-Costa, Sonja J McKeown, Joanne Tan-Cabugao, Tatjana Sauka-Spengler, Marianne E Bronner

“…The critical stem cell transcription factor FoxD3 is expressed by the premigratory and migrating neural crest, an embryonic stem cell population that forms diverse derivatives. …”
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Type-1 (CB1) cannabinoid receptor promotes neuronal differentiation and maturation of neural stem cells. by Claudia Compagnucci, Sara Di Siena, Maria Blaire Bustamante, Daniele Di Giacomo, Monia Di Tommaso, Mauro Maccarrone, Paola Grimaldi, Claudio Sette

“…Neural stem cells (NSCs) are self-renewing cells that can differentiate into multiple neural lineages and repopulate regions of the brain after injury. …”
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Transcriptomic and epigenomic profiling of young and aged spermatogonial stem cells reveals molecular targets regulating differentiation. by Jinyue Liao, Hoi Ching Suen, Alfred Chun Shui Luk, Lele Yang, Annie Wing Tung Lee, Huayu Qi, Tin-Lap Lee

“…Aging leads to the decline in stem cell function and increased risk of paternal age-related genetic diseases. …”
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Retinoic and ascorbic acids induce osteoblast differentiation from human dental pulp mesenchymal stem cells by Lina M. Escobar, José Daniel Escobar, Zita Bendahan, Jaime E. Castellanos

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Modulation of mouse embryonic stem cell proliferation and neural differentiation by the P2X7 receptor. by Talita Glaser, Sophia La Banca de Oliveira, Arquimedes Cheffer, Renata Beco, Patrícia Martins, Maynara Fornazari, Claudiana Lameu, Helio Miranda Costa Junior, Robson Coutinho-Silva, Henning Ulrich

“…<h4>Background</h4>Novel developmental functions have been attributed to the P2X7 receptor (P2X7R) including proliferation stimulation and neural differentiation. …”
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MicroRNA-150 Modulates Adipogenic Differentiation of Adipose-Derived Stem Cells by Targeting Notch3 by Xiang Li, Yu Zhao, Xiuquan Li, Qiao Wang, Qiang Ao, Xiaohong Wang, Xiaohong Tian, Hao Tong, Deyu Kong, Shijie Chang, Shuling Bai, Jun Fan

“…MicroRNAs (miRNAs) influence stem cell functions, including mobilization, proliferation, and differentiation. miR-150 is abundantly expressed in monocytes. …”
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Paving the way to a neural fate – RNA signatures in naive and trans-differentiating mesenchymal stem cells by Caroline Diener, Konstantin Thüre, Annika Engel, Martin Hart, Andreas Keller, Eckart Meese, Ulrike Fischer

“…Neural stem cell marker NES and neuron differentiation marker, including TUBB3 and ENO1, were highly expressed in mesenchymal stem cells and remained so during trans-differentiation. …”
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Functional analysis of human hematopoietic stem cell gene expression using zebrafish. by Craig E Eckfeldt, Eric M Mendenhall, Catherine M Flynn, Tzu-Fei Wang, Michael A Pickart, Suzanne M Grindle, Stephen C Ekker, Catherine M Verfaillie

“…Further characterization of the spry4-deficient zebrafish embryos demonstrated that hematopoietic defects were not due to more widespread defects in the mesodermal development, and therefore represented primary defects in HSC specification, proliferation, and/or differentiation. Overall, this high-throughput screen for the functional validation of differentially expressed genes using a zebrafish model of hematopoiesis represents a major step toward obtaining meaningful information from global gene profiling of HSCs.…”
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Regulatory Functions of microRNAs in Cancer Stem Cells: Mechanism, Facts, and Perspectives by Xingmei Mao, Sixue Peng, Yan Lu, Linjiang Song

“…In recent years, the ongoing investigation and comprehension of tumors have led to significant attention towards cancer stem cells (CSCs). CSCs can facilitate tumor progression via self-renewal, differentiation capabilities, and multidrug resistance. …”
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