EDA1 variants inhibit the odontogenic differentiation and proliferation of human dental pulp stem cells by Yulin Ding, Genqi Lu, Ya Zhao, Yi Zhang, Jing Zhang, Jingle Ma, Yunyun Yuan, Boyu Liu, Wei Liu, Wenjing Shen

“…Further study of these variants could reveal the mechanism by which EDA1 induces tooth development. Methods The following groups of hDPSCs were studied: those expressing wild-type (Wt) EDA1, those expressing EDA1 non-syndromic tooth agenesis (NSTA) variants (NSTA-A259E, NSTA-S374R), those expressing a syndrome type (STA) variant of EDA1 (STA-H252L), and those transformed with the empty vector (NC, negative control). hDPSCs proliferation was assessed using Cell Counting kit 8 assays. …”
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Cluster analysis of Model for End-stage Liver Disease and European System for Cardiac Operative Risk Evaluation for predicting operative mortality after concomitant tricuspid valve... by Kevin Lim, FRCS (Ed), Antony Chin Ching Au, MB ChB, Matthew Ming Hon Hui, MRCS (Ed), Ivan Chi Hin Siu, MRCS (Ed), Simon Chi Ying Chow, FRCS (Ed), Jacky Yan Kit Ho, FRCS (Ed), Song Wan, FRCS (Ed), FACC, Randolph Hung Leung Wong, FRCS (Ed)

“…The models were compared by measuring c-statistic using the Hanley-McNeil method. This was further evaluated with category-free net reclassification improvement index. …”
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Piloting a team-based telemedicine care for hypertension focused on Black patients by Srista Manandhar, Sunit Chhetri, Danielle Sutton, Animita C. Saha, Suneet Kaur, Josh Brown, Jeff Williamson, Kathryn E. Callahan, Justin B. Moore, Yhenneko J. Taylor, Hayden B. Bosworth, Yashashwi Pokharel

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Cerebral microvascular density, blood-brain barrier permeability, and support for neuroinflammation indicate early aging in a Marfan syndrome mouse model by Tala Curry-Koski, Tala Curry-Koski, Liam P. Curtin, Mitra Esfandiarei, Mitra Esfandiarei, Mitra Esfandiarei, Theresa Currier Thomas, Theresa Currier Thomas, Theresa Currier Thomas, Theresa Currier Thomas

“…IntroductionMarfan Syndrome (MFS) is a connective tissue disorder due to mutations in fibrillin-1 (Fbn1), where a Fbn1 missense mutation (Fbn1C1039G/+) can result in systemic increases in the bioavailability and signaling of transforming growth factor-β (TGF-β). In a well-established mouse model of MFS (Fbn1C1041G/+), pre-mature aging of the aortic wall and the progression of aortic root aneurysm are observed by 6-month-of-age. …”
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Impact of Helicobacter pylori infection on iron deficiency anemia in children: a systematic review and meta-analysis with early intervention implications by Ziteng Wang, Wentao Tan, Huanhuan Xiong, Jiali Huang, Herui Wei, Mengqi Li, Jing Luo, Wen An, Lingling He, Jiali Ma, Fan Xiao, Fan Xiao, Fan Xiao, Fan Xiao, Hongshan Wei

“…Odds ratios (ORs) and 95% confidence intervals (CIs) were extracted from the studies, and data were transformed for meta-analysis. Heterogeneity was evaluated using the I2statistic, and homogeneity was tested with the chi-square test. …”
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Risk factors for new-onset diabetes after transplantation in kidney transplant recipients: own data and meta-analysis by Maria S. Novikova, Larisa O. Minushkina, Oleg N. Kotenko, Dmitry A. Zateyshchikov, Olga I. Boeva, Sona S. Allazova, Eugene M. Shilov, Olga M. Koteshkova, Mikhail B. Antsiferov

“…To compare risk factors for new-onset diabetes after transplantation (NODAT) among renal transplant recipients (RTRs) from 1989 to 2018 in the City Clinical Hospital №52, with a systematic analysis of published studies on this topic. Materials and methods. In a 30-year (1989–2018) retrospective study, we found statistically significant differences in age, gender, polycystic kidney disease, cadaveric kidney, cyclosporine, i-mTOR, and steroids between two groups of recipients with and without NODAT. …”
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Uncovering abnormal gray and white matter connectivity patterns in Alzheimer’s disease spectrum: a dynamic graph theory analysis for early detection by Juanjuan Jiang, Tao Kang, Ronghua Ling, Yingqian Liu, Jiuai Sun, Yiming Li, Xiaoou Li, Hui Yang, Bingcang Huang, the Alzheimer’s Disease Neuroimaging Initiative

“…DFC metrics (standard deviation of Fisher z-transformed correlations) were used to identify group differences and classify AD spectrum stages. …”
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Association between psychiatric symptoms with multiple peripheral blood sample test: a 10-year retrospective study by Jianqing Qiu, Cheng Yu, Yalan Kuang, Yao Hu, Ting Zhu, Ting Zhu, Ke Qin, Wei Zhang, Wei Zhang, Wei Zhang, Wei Zhang

“…In this study, we investigated the associations between peripheral blood test indexes with various symptom levels of major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SCZ) to explore the availability of peripheral blood test indexes.MethodsWe extracted cases diagnosed with MDD, BD, and SCZ at West China Hospital from 2009 to 2021, translated their main complaints into Research Domain Criteria (RDoC) symptom severity scores using nature language processing (NLP), and collected their detailed psychiatric symptoms and peripheral blood test results. …”
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Efficacy of traditional Chinese medicine injections for treating idiopathic pulmonary fibrosis: A systematic review and network meta-analysis. by Shuai-Yang Huang, Hong-Sheng Cui, Ming-Sheng Lyu, Gui-Rui Huang, Dan Hou, Ming-Xia Yu

“…However, there were limitations to the conclusions of this study due to quality control differences in the included trials.…”
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Representation Learning of Multi-Spectral Earth Observation Time Series and Evaluation for Crop Type Classification by Andrea González-Ramírez, Clement Atzberger, Deni Torres-Roman, Josué López

“…Our method uses only <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mn>6.8</mn><mi>k</mi></mrow></semantics></math></inline-formula> parameters, i.e., <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>∼</mo><mspace width="-3.0pt"></mspace><mn>400</mn><mi>x</mi></mrow></semantics></math></inline-formula> fewer than OmnicsCNN and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>∼</mo><mspace width="-3.0pt"></mspace><mn>27</mn><mi>x</mi></mrow></semantics></math></inline-formula> fewer than Transformer. …”
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Clinical application value of intracavitary PRP infusion combined with IVF-FET in patients with chronic endometritis by ZHANG Xiaotong, HAO Xiaoyuan, FANG Rui, HU Shuyao, MA Linkun, ZHAO Yaqi, HAN Wei

“…[Results] No significant differences in endometrial thickness were observed among the three groups during the transformation phase (P>0.05). …”
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Developing a Model of Wisdom Based on Successful Intelligence and Psychological Well-Being in Students: The Mediating Role of Creativity by Rasool Kordnoghabi, Saeed Veisi

“…Transformative creativity be directed inward (self-interest), outward (common good and public interest) or both, which greatly contributes to the wisdom of the individual. …”
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Nucleus accumbens functional connectivity changes underlying alcohol expectancies in bipolar disorder and prospective alcohol outcomes: a within-subject randomized placebo-controll... by Elizabeth T. C. Lippard, Elizabeth T. C. Lippard, Elizabeth T. C. Lippard, Elizabeth T. C. Lippard, Elizabeth T. C. Lippard, Dylan E. Kirsch, Dylan E. Kirsch, Dylan E. Kirsch, Dylan E. Kirsch, Vanessa Le, Vanessa Le, Skyler Lee, Nadia Bibb, Kaitlyn Meek, Raquel Kosted, Ansley Huffman, J. R. C. Almeida, Kim Fromme, Kim Fromme, Stephen M. Strakowski, Stephen M. Strakowski, Stephen M. Strakowski

“…Fisher-transformed correlation coefficients between ROIs and seed-to-clusters showing a significant group-by-condition (placebo, pre-beverage rsfMRI) interaction were calculated. …”
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Performance of popular large language models in glaucoma patient education: A randomized controlled study by Yuyu Cao, Wei Lu, Runhan Shi, Fuying Liu, Steven Liu, Xinwei Xu, Jin Yang, Guangyu Rong, Changchang Xin, Xujiao Zhou, Xinghuai Sun, Jiaxu Hong

“…Purpose: The advent of chatbots based on large language models (LLMs), such as ChatGPT, has significantly transformed knowledge acquisition. However, the application of LLMs in glaucoma patient education remains elusive. …”
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Theranostic Potential of the iPSMA-Bombesin Radioligand in Patients with Metastatic Prostate Cancer: A Pilot Study by Sofía González-Rueda, Osvaldo García-Pérez, Myrna Luna-Gutiérrez, Blanca Ocampo-García, Clara Santos-Cuevas, Gerardo Ramírez-Nava, Joel Vargas-Ahumada, Erika Azorín-Vega, Guillermina Ferro-Flores, Laura Meléndez-Alafort

“…[^99mTc]Tc-iPSMA-BN appears to have better lesion detection in patients with aggressive histologic transformation. Two-way ANOVA analysis revealed a significant difference in TBR values between patients with mCRPC and mCSPC (<i>p</i> < 0.05) but no difference between [¹⁸F]-PSMA-1007 and [^99mTc]Tc-iPSMA-BN (<i>p</i> > 0.05). …”
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Challenges Caused by Using New Technologies in Holding Public Hearings of Iranian Criminal Courts by Mozhgan Nemati, Nasrin Mehra, Morteza Rasteh

“…Due to the lack of necessary infrastructure and the lack of feeling the need to implement this sample of digital transformation in the judicial system of the country, the implementation of this regulation was practically delayed until the end of 2019. …”

Assessment of antibiotic utilization patterns in an Indian Level-1 Trauma Center: a pilot study exploring days of antibiotic spectrum coverage and defined daily doses using WHO AWa... by M Nizam Ahmed, Arpan Kumar Thakur, Smriti Srivastava, Aparna Ningombam, Madhavi Kirti, Sushma Sagar, Keshav Goyal, Subodh Kumar, Ashish Bindra, Gyaninder Pal Singh, Navdeep Sokhal, Richa Aggarwal, Vijay Sharma, Samarth Mittal, Kamran Farooque, Purva Mathur

“…However, DASC’s novel, spectrum-focused approach offers a transformative tool for antibiotic stewardship, supporting targeted de-escalation and improved benchmarking. …”
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Supporting antiretroviral therapy uptake and adherence: the SUPA research programme and RCT by Rob Horne, Caroline Sabin, Trudie Chalder, Vanessa Cooper, Lucy Campbell, Elizabeth Glendinning, Iris Mosweu, Paul McCrone

“…Background Antiretroviral therapy has transformed human immunodeficiency virus infection intoa chronic condition associated with normal life expectancy. …”
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Modeling and finite element simulation of temperature field in rail abrasive belt grinding by Haipeng WANG, Jianyong LI, Chaoyue ZHAO, Yueming LIU

“…Based on the transient point heat transfer model in heat conduction theory, the multiple discrete moving point heat source set is transformed into a moving surface heat source model according to the generation and conduction mechanism of grinding heat. …”
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Presenting the model of social entrepreneurship in the development of rural tourism in the target villages of Gilan province by Fatemeh Doozandeh Ziabari, hamed fallah tafti, Mir Mohammad Asadi, Mahdi Basouli

“…The results of the qualitative questionnaire and open interview with the sample members, after taking notes and transferring to the system, were analyzed using coding and the data-based method and Maxqda software, and the output and the final model were reported. …”
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