Suggested Topics within your search.
Suggested Topics within your search.
-
6361
Research on the Economic Loss Model of Invasive Alien Species Based on Multidimensional Data Spatialization—A Case Study of Economic Losses Caused by <i>Hyphantria cunea</i> in Jia...
Published 2025-05-01“…To address these limitations, we innovatively integrated three models: (1) Difference-in-Differences (DID) quantified causal economic impacts through spatiotemporal comparison of infested/non-infested areas; (2) GeoDetector identified key spatial drivers via stratified heterogeneity analysis; (3) MaxEnt projected ecological suitability under climate scenarios. …”
Get full text
Article -
6362
Protective effect of erythropoietin preconditioning on kidney ischemia-reperfusion injury
Published 2017-01-01“…Objective To explore the protective effect of erythropoietin(EPO)on renal ischemia-reperfusion injury(IRI)in rats.Methods Thirty male SD rats were randomly divided into sham operation group(Sham),renal IRI group(IRI)and EPO pretreatment group(EPO),10 rats in each group.The renal IRI model was constructed by clamping the left renal pedicle for 1h,removing the right kidney,and reperfusion for 24 h.In EPO group,EPO(1 000U/kg)was intraperitoneally injected at 1hbefore operation,while Sham group and IRI group were intraperitoneally injected with equal volume of normal saline.The left renal pedicle was clamped for 45 min in EPO and IRI groups,but not in Sham group.Renal perfusion was restored for 24 h,and then kidneys and serum were obtained.Enzyme linked immunosorbent assay(ELISA)was used to detect serum creatinine(SCr),blood urea nitrogen(BUN),pro-inflammatory cytokines [interleukin-6(IL-6);interferon gamma(IFN-γ)and tumor necrosis factor alpha(TNF-α)]and anti-inflammatory cytokine(IL-10 and TGF-β).The reverse transcriptase polymerase chain reaction(RT-PCR)was used to detect renal pro-inflammatory cytokines(IL-6,IFN-γand TNF-α)and anti-inflammatory cytokines[IL-10 and transforming growth factor beta(TGF-β)]mRNA expression levels.Western blotting was used to detect EPO receptor(EPOR),phosphorylated EPOR(p-EPOR),tyrosine kinase-2(JAK2),signal transducer and activator of transcription 3(STAT3),phosphorylated JAK2(p-JAK2),phosphorylated STAT3(pSTAT3)protein expression levels.Periodic acid Schiff staining(PAS)was used to examine the pathological changes of renal tissues.Results As compared with Sham group,the expression levels of pEPOR,p-JAK2,p-STAT3,SCr,BUN,IL-6,TNF-αand IFN-γwere significantly increased,pathological changes of renal tissues obviously alleviated,and expression levels of IL-10 and TGF-βwere markedly reduced in IRI group.There was no significant difference in EPOR,JAK2 and STAT3levels between Sham group and IRI group.As compared with IRI group,the expression levels of p-EPOR,p-JAK2,p-STAT3,IL-10 and TGF-βwere significantly increased,the levels of SCr,BUN,IL-6,TNF-αand IFN-γwere significantly reduced,and the pathological changes of renal tissues were significantly alleviated in EPO group,but there was no significant difference in EPOR,JAK2 and STAT3expression between IRI group and EPO group.Conclusions EPO preconditioning can alleviate inflammation by inhibiting renal IRI,which may be related with the activation of EPOR/JAK2/STAT3 signaling pathway.…”
Get full text
Article -
6363
The effect of autologous platelet-rich plasma intrauterine perfusion on pregnancy outcomes of frozen-thawed embryo transfer in patients with chronic endometritis
Published 2025-08-01“…Endometrial thickness on the day before transformation was significantly higher in the PRP group compared to the control group (10.58 ± 1.78 mm vs. 9.79 ± 1.58 mm, P = 0.001). …”
Get full text
Article -
6364
Outcomes of Noninvasive Positive Pressure Ventilation in Acute Respiratory Distress Syndrome and Their Predictors: A National Cohort
Published 2019-01-01“…Linear regression of log-transformed LOS and logistic regression of binary outcomes were used to test for associations. …”
Get full text
Article -
6365
Compositional associations of 24-h physical activities, sedentary time and sleep with depressive symptoms in urban and rural residents: a cross-sectional study
Published 2025-04-01“…Methods The study population consisted of 4295 adults, aged 46 years, from the Northern Finland Birth Cohort 1966. …”
Get full text
Article -
6366
Research on pricing zone division strategy based on natural gas tariff affordability
Published 2024-10-01“…This proposed method results in closer tariff affordability within each pricing zone, thereby facilitating the transformation of the approach to dividing natural gas pricing zones.…”
Get full text
Article -
6367
Urolithiasis complicated by chronic obstructive pyelonephritis in patients with concomitant diseases of the cardiovascular system
Published 2021-12-01“…To study the features of chronic obstructive pyelonephritis in patients with recurrent nephrolithiasis and concomitant diseases of the cardiovascular system.Materials and methods. The study included a total of 618 patients suffering from recurrent nephrolithiasis complicated by ChOP. …”
Get full text
Article -
6368
-
6369
Unlocking ecological insights from sub‐seasonal visible‐to‐shortwave infrared imaging spectroscopy: The SHIFT campaign
Published 2025-03-01“…Abstract We stand at the threshold of a transformative era in Earth observation, marked by space‐borne visible‐to‐shortwave infrared (VSWIR) imaging spectrometers that promise consistent global observations of ecosystem function, phenology, and inter‐ and intra‐annual change. …”
Get full text
Article -
6370
Tripartite Motif-Containing 1 Influences the Prognosis of Cervical Cancer
Published 2025-05-01“…Notably, within the context of human papillomavirus (HPV) infection, the GSE67522 dataset highlighted the pivotal role of TRIM11 during malignant transformation, show a significant difference in expression between HPV-positive cancer tissues and matched normal cervical epithelia (p < 0.001). …”
Get full text
Article -
6371
Mental health status of the European population and its determinants: A cross-national comparison study
Published 2025-01-01“…Exploratory unadjusted bivariate correlations between KPIs-transformed scores were run. Results Based on the KPIs-transformed scores, Slovakia (8.3), Cyprus (7.8), and Greece (7.1) had the best MH status, while Sweden (3.1), UK (2.6), and The Netherlands (2.1) had the poorest MH status. …”
Get full text
Article -
6372
-
6373
Development and Validation of the Digital Sensitivity Scale for Adults: Cross-Sectional Observational Study
Published 2025-01-01“… BackgroundThe COVID-19 pandemic has accelerated the digitalization of modern society, extending digital transformation to daily life and psychological evaluation and treatment. …”
Get full text
Article -
6374
-
6375
Triple cardiovascular disease detection with an artificial intelligence-enabled stethoscope (TRICORDER): design and rationale for a decentralised, real-world cluster-randomised con...
Published 2025-05-01“…Introduction Early detection of cardiovascular disease in primary care is a public health priority, for which the clinical and cost-effectiveness of an artificial intelligence-enabled stethoscope that detects left ventricular systolic dysfunction, atrial fibrillation and cardiac murmurs is unproven but potentially transformative.Methods and analysis TRICORDER is a pragmatic, two-arm, multi-centre (decentralised), cluster-randomised controlled trial and implementation study. …”
Get full text
Article -
6376
Pre-Pregnancy Weight and Weight Gain During Pregnancy and Their Effect on Child Birth Weight in Gaza Governorate: Cross-Sectional Study
Published 2023-08-01“…However, most dietary assessment methods are impractical for use in maternal care. …”
Get full text
Article -
6377
Evaluating the role of active TGF-β1 as inflammatory biomarker in Kashmiri (North-Indian) patients with systemic sclerosis: a case-control study
Published 2024-12-01“…Abstract Background As a master immune system regulator, transforming growth factor β1 (TGF-β1) is closely linked to the complicated pathophysiology and development of systemic sclerosis (SSc), a multisystem fibrotic disease. …”
Get full text
Article -
6378
A Study of Mixed Non-Motorized Traffic Flow Characteristics and Capacity Based on Multi-Source Video Data
Published 2024-10-01“…The fitted parametric models are analyzed by transforming them from the time domain to the frequency domain, and the power spectrum estimation model is then calculated. …”
Get full text
Article -
6379
-
6380