Cerebral microvascular density, blood-brain barrier permeability, and support for neuroinflammation indicate early aging in a Marfan syndrome mouse model by Tala Curry-Koski, Tala Curry-Koski, Liam P. Curtin, Mitra Esfandiarei, Mitra Esfandiarei, Mitra Esfandiarei, Theresa Currier Thomas, Theresa Currier Thomas, Theresa Currier Thomas, Theresa Currier Thomas

“…IntroductionMarfan Syndrome (MFS) is a connective tissue disorder due to mutations in fibrillin-1 (Fbn1), where a Fbn1 missense mutation (Fbn1C1039G/+) can result in systemic increases in the bioavailability and signaling of transforming growth factor-β (TGF-β). In a well-established mouse model of MFS (Fbn1C1041G/+), pre-mature aging of the aortic wall and the progression of aortic root aneurysm are observed by 6-month-of-age. …”
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Impact of Helicobacter pylori infection on iron deficiency anemia in children: a systematic review and meta-analysis with early intervention implications by Ziteng Wang, Wentao Tan, Huanhuan Xiong, Jiali Huang, Herui Wei, Mengqi Li, Jing Luo, Wen An, Lingling He, Jiali Ma, Fan Xiao, Fan Xiao, Fan Xiao, Fan Xiao, Hongshan Wei

“…Odds ratios (ORs) and 95% confidence intervals (CIs) were extracted from the studies, and data were transformed for meta-analysis. Heterogeneity was evaluated using the I2statistic, and homogeneity was tested with the chi-square test. …”
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Caractérisation d'une modification éventuelle de la relation pluie-débit en Afrique de l'Ouest : cas du bassin versant du N'zi (Bandama) en Côte d'Ivoire, Thèse de Doctorat, Univer... by Amani Michel Kouassi

“…L'objectif de ce travail est d'identifier des tendances au sein de la relation pluie-débit et d'étudier ses impacts sur les ressources en eau du bassin versant du N'zi (Bandama) dans un contexte de variabilité hydroclimatique et de modification de l'occupation du sol. Les résultats des différentes méthodes statistiques appliquées aux séries chronologiques de variables caractéristiques du régime pluviométrique et hydrométrique montrent que globalement sur le bassin versant du N'zi (Bandama), ces variables sont en baisse depuis les années 1970. …”
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Risk factors for new-onset diabetes after transplantation in kidney transplant recipients: own data and meta-analysis by Maria S. Novikova, Larisa O. Minushkina, Oleg N. Kotenko, Dmitry A. Zateyshchikov, Olga I. Boeva, Sona S. Allazova, Eugene M. Shilov, Olga M. Koteshkova, Mikhail B. Antsiferov

“…To compare risk factors for new-onset diabetes after transplantation (NODAT) among renal transplant recipients (RTRs) from 1989 to 2018 in the City Clinical Hospital №52, with a systematic analysis of published studies on this topic. Materials and methods. In a 30-year (1989–2018) retrospective study, we found statistically significant differences in age, gender, polycystic kidney disease, cadaveric kidney, cyclosporine, i-mTOR, and steroids between two groups of recipients with and without NODAT. …”
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Uncovering abnormal gray and white matter connectivity patterns in Alzheimer’s disease spectrum: a dynamic graph theory analysis for early detection by Juanjuan Jiang, Tao Kang, Ronghua Ling, Yingqian Liu, Jiuai Sun, Yiming Li, Xiaoou Li, Hui Yang, Bingcang Huang, the Alzheimer’s Disease Neuroimaging Initiative

“…DFC metrics (standard deviation of Fisher z-transformed correlations) were used to identify group differences and classify AD spectrum stages. …”
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Association between psychiatric symptoms with multiple peripheral blood sample test: a 10-year retrospective study by Jianqing Qiu, Cheng Yu, Yalan Kuang, Yao Hu, Ting Zhu, Ting Zhu, Ke Qin, Wei Zhang, Wei Zhang, Wei Zhang, Wei Zhang

“…In this study, we investigated the associations between peripheral blood test indexes with various symptom levels of major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SCZ) to explore the availability of peripheral blood test indexes.MethodsWe extracted cases diagnosed with MDD, BD, and SCZ at West China Hospital from 2009 to 2021, translated their main complaints into Research Domain Criteria (RDoC) symptom severity scores using nature language processing (NLP), and collected their detailed psychiatric symptoms and peripheral blood test results. …”
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Efficacy of traditional Chinese medicine injections for treating idiopathic pulmonary fibrosis: A systematic review and network meta-analysis. by Shuai-Yang Huang, Hong-Sheng Cui, Ming-Sheng Lyu, Gui-Rui Huang, Dan Hou, Ming-Xia Yu

“…However, there were limitations to the conclusions of this study due to quality control differences in the included trials.…”
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Real-world use of complement inhibitors for haemolytic uraemic syndrome: an analysis of the European Rare Kidney Disease Registry cohortResearch in context by Aleksandra Vujović, Anne-Laure Sellier-Leclerc, Maria Cristina Mancuso, Olivia Boyer, Atif Awan, Antonio Gargiulo, Sebastian Loos, Marc Fila, Augustina Jankauskiene, Gema Ariceta, Nele Kanzelmeyer, Enrico Vidal, Maria Van Dyck, Tanja Kersnik Levart, Naděžda Šimánková, Stephane Decramer, Jonas Hofstetter, Marina Vivarelli, Savino Sciascia, Nicole C.A.J. van de Kar, Franz Schaefer, Nicole C.A.J. van de Kar, Marina Vivarelli, Savino Sciascia, David Kavanagh, René Andersen, Mia Faerch, Soren Rittig, Miquel Blasco, Pedro Arango Sancho, Alvaro Madrid, Gema Ariceta, Loreto Gesualdo, Camillo Carrara, Piero Ruggenenti, Kai-Uwe Eckardt, Jan Halbritter, Dominik Müller, Adrian Schreiber, Evelyn Seelow, Yahsou Delmas, Jerome Harambat, Brigitte Llanas, Nathalie Godefroid, Eric Goffin, Johann Morelle, Adrian Catalin Lungu, George Reusz, Péter Sallay, Attila Szabo, Kalman Tory, Jan Ulrich Becker, Kathrin Burgmaier, Volker Burst, Sandra Habbig, Max Liebau, Roman-Ulrich Mueller, Lutz Weber, Mette Damholt, Anne-Lise Kamper, Karl Emil Nelveg-Kristensen, Hanne Nørgaard, Ida Maria Schmidt, Soeren Soerensen, Wladimir Szpirt, Agnieszka Jaskólska, Monika Miklaszewska, Anna Moczulska, Elżbieta Szczęsny-Choruz, Katarzyna Zachwieja, Peter Conlon, Atif Awan, Michael Wiesener, Anja Büscher, Rainer Büscher, Lars Pape, Francesca Becherucci, Paola Romagnani, Ann Raes, Thomas Renson, Evelien Snauwaert, Johan Vande Walle, Jill Vanmassenhove, Mark Eijgelsheim, Casper Franssen, Coen Stegeman, Florian Grahammer, Thomas Henne, Tobias Huber, Christian Krebs, Sebastian Loos, Anne Mühlig, Jun Oh, Ulf Panzer, Raphael Schild, Jessica Kaufeld, Stefanie Haeberle, Franz Schaefer, Tanja Wlodkowski, Juuso Tainio, Elisa Ylinen, Obbo Bredewold, Wieneke Michels, Dorien Peters, Antonius Rabelink, Arghya Ray, Joris Rotmans, Siebe Spijker, Y.K. Onno Teng, Kathleen Claes, Noel Knops, Tanja Kersnik Levart, Anamarija Meglič, Gregor Novljan, Agnieszka Gach, Monika Pawlak-Bratkowska, Małgorzata Stańczyk, Marcin Tkaczyk, Pierre Cochat, Anne-Laure Sellier-Leclerc, Teresa Cavero, Eduardo Guiterrez, Joaquin Martinez, Enrique Morales, Hernando Trujillo, Gianluigi Ardissino, Valentina Capone, Sara Testa, Denis Morin, Martin Konrad, Ilaria Luongo, Gabriele Malgieri, Luigi Annicchiarico Petruzzelli, Wilbert van der Meijden, Jack Wetzels, Mattia Parolin, Enrico Vidal, Thérésa Kwon, Olivia Boyer, Aude Servais, Laurent Mesnard, Alena Parikova, Silvie Rajnochova-Bloudickova, Janka Slatinska, Ondrej Viklicky, Martin Bezdicka, Nadezda Simankova, Dana Thomasova, Jakub Zieg, Francesco Emma, Rocco Baccaro, Giuseppe Grandaliano, Alessandro Naticchia, Francesco Pesce, Margherita Baldassarri, Andrea Guarnieri, Anna Maria Pinto, Alessandra Renieri, Stephane Decramer, Stanislas Faguer, David Ribes, Thomas Simon, Stephanie Tellier, Daniel Gale, Christoph Licht, Michal Malina, Candice Roufosse, Neil Sheerin, Susana Carvajal Arjona, Renée de Wildt, Uwe Korst, Christiane Mockenhaupt, Francisco Monfort, Mireya Vicenta Rios Carratala

“…Summary: Background: Although terminal complement inhibitors transformed the prognosis of atypical haemolytic uraemic syndrome (aHUS) from dismal to favourable, treatment approaches vary due to the intermittent disease nature and high costs. …”
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Gas exchange efficiency slopes to assess exercise tolerance in chronic obstructive pulmonary disease by Hiromi Yanagi, Keisuke Miki, Kazumi Koyama, Satoshi Miyamoto, Yasuhiro Mihashi, Yuka Nagata, Kazuki Hashimoto, Hisako Hashimoto, Mari Fukai, Tomonori Maekura, Rika Yonezawa, Shizuka Sakaguchi, Takuro Nii, Takanori Matsuki, Kazuyuki Tsujino, Hiroshi Kida

“…., the slope of oxygen uptake ( $$\rm{\dot V}$$ O2) versus the logarithmically transformed $$\rm{\dot V}$$ E, has rarely been reported. …”
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Structural and functional changes of the heart in patients with chronic ischemic heart failure, associated with renal dysfunction by D. A. Lashkul

“…Thus, the progressive decrease GFR in patients with ischemic chronic heart failure accompanied geometric and hemodynamic transformation that leads to severe diastolic dysfunction.…”
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Weighted Family History Density of Substance Use: Influence on Participant Substance Use Onset, Duration, and Escalation by Litteral CA, Martel MM, Mattingly DT, Moore JX

“…Substance preference concordance and sex-specific links between affected family members and participants were also assessed.Methods: A cross-sectional analysis of the National Epidemiological Survey on Alcohol and Related Conditions III (NESARC-III) included 36,309 adults. …”
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Efficacy and Safety of Afatinib Plus Bevacizumab as First‐Line Treatment for Advanced NSCLC Patients With Epidermal Growth Factor Receptor (EGFR) Mutations: A Multicenter, Phase II... by Huiyang Shi, Miaohan Wang, Junling Li, Shi Jin, Minglei Zhuo, Jun Zhao, Hongxia Zhang, Meng Yang, Qingfang Shi, Haifeng Qin, Guilan Dong, Dongmei Lan, Zhong Dai, Yu Feng, Haohua Zhu, Jingyu Lu, Kai Zhu, Yuankai Shi, Xingsheng Hu

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Rural Landscape Characters and Spatial Correlation Mechanism in the Tiaoxi River – Canal Basin in Zhejiang Province by Lin ZHANG, You ZUO, Binyi LIU

“…And significant region − basin differences are explored from the perspectives of spatial proportion, layout pattern, and coupling relationship. …”
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The Effectiveness of Psychological Well-Being Training based on the PERMA Model for 14 to 16-Year-Old Girls with Anxiety Symptoms Zahra Daneshian: M.A. Student of Child and Adoles... by zahra danesian, Shahriar Shahidi, Saeed Ghanbari

“…However, no significant differences were found for positive emotion, positive relationships, meaning, or achievement. …”
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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…Scientists have explored xenotransplantation methods for decades, but research with vital organ xenotransplants has been in largely haphazard and non-controlled studies, which demonstrated only short-duration survival for recipients.…”
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