Re-Infection Outcomes Following One- And Two-Stage Surgical Revision of Infected Knee Prosthesis: A Systematic Review and Meta-Analysis. by Setor K Kunutsor, Michael R Whitehouse, Erik Lenguerrand, Ashley W Blom, Andrew D Beswick, INFORM Team

“…We therefore sought to ask if there was a difference in re-infection rates and other clinical outcomes when comparing the one-stage to the two-stage revision strategy.…”
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Effects of Yunnan Baiyao retention enema combined with mesalazine enteric-coated tablets and bifidobacterium triple viable capsules for treating ulcerative colitis by Liu Junjie, Gao Jian, Li Shuling

“…[Objectives] To determine the effects of Yunnan Baiyao retention enema combined with mesalazine enteric-coated tablets and bifidobacterium triple viable capsules for treating ulcerative colitis (UC). [Methods] Sixty patients with UC treated at our hospital between January 2020 and June 2021 were randomly divided into the treatment group (n=30) and the control group (n=30). …”
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Ex vivo biotransformation of lady’s mantle extracts via the human gut microbiota: the formation of phenolic metabolites and their impact on human normal and colon cancer cell lines... by Katarzyna Jakimiuk, Aleksandra Kruk, Marta Kinga Lemieszek, Jakub W. Strawa, Sebastian Granica, Adrian Wiater, Michał Tomczyk

“…The non-transformed AV extract affected neither normal nor cancer colon cells, indicating the beneficial effect of the biotransformation procedure on the anticancer properties of the evaluated extracts. …”
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Prenatal exposure to phthalates and preschool children’s intellectual scores: Effect modification by child sex by Carly V. Goodman, Christine Till, Sietske Berghuis, Joseph M. Braun, Gina Muckle, Aimin Chen, Youssef Oulhote, Bruce Lanphear, Jillian Ashley-Martin, Tye E. Arbuckle

“…Associations between ΣDiDPm and VIQ and MMP and PIQ differed by child sex (negative for boys and positive for girls, respectively). …”
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Role of CDH1 gene variants and E-cadherin localization in gastric mucosal cancerization by Yunbo Wu, Yunzhan Zhang, Yunkai Dai, Qi Luo, Shaoyang Lan, Xu Chen, Weijing Chen, Ruliu Li, Ling Hu

“…The loss and ectopic expression of E-cadherin may be significant risk factors for malignant transformation in the gastric mucosa.…”
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Modeling and finite element simulation of temperature field in rail abrasive belt grinding by Haipeng WANG, Jianyong LI, Chaoyue ZHAO, Yueming LIU

“…Based on the transient point heat transfer model in heat conduction theory, the multiple discrete moving point heat source set is transformed into a moving surface heat source model according to the generation and conduction mechanism of grinding heat. …”
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In Vitro Anthelmintic Activities of Khaya anthotheca and Faidherbia albida Extracts Used in Chad by Traditional Healers for the Treatment of Helminthiasis and In Silico Study of Ph... by Baigomen Christalin, Masoud Besati, Noumedem Anangmo Christelle Nadia, Mahdi Yaghoobi, Yamssi Cédric, Claire Ciancia, Mounvera Abdel Azizi, Gamago Nkadeu Guy-Armand, Vincent Khan Payne, Haibo Hu

“…Examining the ADME properties of these compounds also supports the potential of these ligands to be transformed into pharmaceutical forms.…”
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Urinary Metabolic Profiling During Epileptogenesis in Rat Model of Lithium–Pilocarpine-Induced Temporal Lobe Epilepsy by Fatma Merve Antmen, Emir Matpan, Ekin Dongel Dayanc, Eylem Ozge Savas, Yunus Eken, Dilan Acar, Alara Ak, Begum Ozefe, Damla Sakar, Ufuk Canozer, Sehla Nurefsan Sancak, Ozkan Ozdemir, Osman Ugur Sezerman, Ahmet Tarık Baykal, Mustafa Serteser, Guldal Suyen

“…<b>Background/Objectives</b>: Temporal lobe epilepsy (TLE) often develops following an initial brain injury, where specific triggers lead to epileptogenesis—a process transforming a healthy brain into one prone to spontaneous, recurrent seizures. …”
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Interventions designed to promote the consumption of locally produced foods: a scoping review by Emily Haynes, Catherine R. Brown, Cassandra Halliday, Lutgardo Alcantara, Cristobal Cayetano, Lota Creencia, Lea Janine Gajardo, Amanda Goodwin, Cornelia Guell, Christina Howitt, Viliamu Iese, Alison Karley, John Roderick Madarcos, Karen Madarcos, Karyn Morrissey, Khadija Patel, Natasha Sobers, Filipe Veisa, Madhuvanti M. Murphy, Nigel Unwin, Nigel Unwin

“…IntroductionFood system transformation is required for planetary health. Localizing food systems and applying agroecological principles to food production and supply have been suggested to support a resilient and sustainable food system. …”
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Depletion of regulatory T cells enhances the T cell response induced by the neoantigen vaccine with weak immunogenicity by Ruichen Huang, Qiao Zhou, Jiajun Liu, Yang Xia, Yang Jiao, Bi Zhao, Tangtao Feng, Haosu Zhou, Xiuyan Song, Hao Qin, Jun Wang, Lan Cheng, Yunye Ning, Qinying Sun, Yanfang Liu, Xiaoping Su, Yuchao Dong, Wei Zhang

“…Conclusion: Our research first revealed that inhibiting the normal function of Tregs transformed “weaker” neoantigens into “stronger” ones, while also contributing to the proliferation of NRT cells. …”
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Novel potential biomarkers for predicting childhood caries via metagenomic analysis by Hui Zhang, Hui Zhang, Xiao Zheng, Xiao Zheng, Xiao Zheng, Yongmao Huang, Yongmao Huang, Yuanqiang Zou, Tao Zhang, Maria Alice Repo, Maria Alice Repo, Meixiang Yin, Yang You, Zhuye Jie, Wen-an Xu, Wen-an Xu

“…The predictive capacity of the identified biomarkers warrants further investigation for early caries detection and intervention.Clinical SignificanceThe identification of novel biomarkers through metagenomic analysis enables early detection and targeted intervention for childhood caries, potentially transforming children dental care and significantly improving long-term oral health outcomes.…”
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Exploring the predictive “psycho-biomarkers” for checkpoint immunotherapy in cancer by Qian Zuo, Jieting Chen, Jieting Chen, Xi Xiao, Yan Dai, Liushan Chen, Liushan Chen, Yuqi Liang, Yingchao Wu, Junfeng Huang, Rutao Cui, Rui Xu, Qianjun Chen, Qianjun Chen, Qianjun Chen, Qianjun Chen

“…BackgroundIn recent decades, cancer immunotherapy has transformed the treatment landscape, offering significant advantages over traditional therapies by improving progression-free survival (PFS) and overall survival (OS). …”
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Beliefs and perceptions of genetic testing by clinical, demographic, and health characteristics: A U.S.-based study utilizing the health information national trends (HINTS) survey by Pranali G. Patel, Marvin E. Langston, Justin X. Moore, Yunan Han, Marquita W. Lewis-Thames, Lindsay Fuzzell, Saira Khan

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Accuracy of a novel calibratable real-time continuous glucose monitoring device based on FreeStyle libre in- and out-of-hospital by Zhenghao Wu, Zhenghao Wu, Zhaoxiang Liu, Wenhui Zhao, Shaocheng Wang, Liangbiao Gu, Jianzhong Xiao

“…This study aim to validate the consistency and clinical accuracy of the product by comparing the capillary blood glucose (CBG) with CGM data in both in-hospital and outpatient scenarios.MethodsResults of CGM devices were compared with random capillary glucose values from users in both in-hospital and outpatient settings. …”
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CILO-CLOP Trial: Cilostazol Versus Clopidogrel in Acute Moderate and Moderate-to-Severe Ischemic Stroke: A Randomized Controlled Multicenter Trial by Mohamed G. Zeinhom, Mohamed Ismaiel, Mohamed Fouad Elsayed Khalil, Mohamed Ahmed Almoataz, Tarek Youssif Omar, Ahmed Mohamed Ali Daabis, Hossam Mohamed Refat, Ahmed Ahmed Mohamed Kamal Ebied, Noha Abdelwahed, Ahmed Zaki Omar Akl, Emad Labib Abdelhamid Mahmoud, Salah Ibrahim Ahmed, Sherihan Rezk Ahmed

“…There were no significant differences between the two groups regarding the modified Rankin scale (mRS) score after 3 months or in the non-hemorrhagic side effects. …”
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The Palatability Dance—SNPs and Genetic Taste Scores of Umami, Sweet, and Bitter Taste Receptors (TAS1R and TAS2R Genes) by Jean Leite, Jaqueline Pereira, Marcelo Rogero, Regina Fisberg, Flávia Sarti

“…Unraveling associations between SNPs and food intake might help guide public policies towards healthier food behavior considering genetic differences, i.e., personalized nutrition.…”
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Abstract 229: Recanalization Rate in Mechanical Thrombectomy in Patients With Elevated LDL‐C Levels by Xiaoyi Gao, Kara Christopher, Wilson Rodriguez, Weston Gordon, Guillermo Linares

“…We also aim to investigate whether LDL‐C levels affect MT recanalization rate. Methods We reviewed the records of 223 patients who received MT at our institution from 2018‐2023. …”
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Multicentre assessment of transperineal targeted prostate biopsy performed as part of a targeted and systematic biopsy diagnostic strategy in men without previous prostate biopsies by Mohammed Sheweita, Liam Blaney, Jon Oxley, Douglas Kopcke, Stefanos Bolomytis, Paul Burn, Adrian Andreou, Jon Heron, Raj Persad, Nick Burns‐Cox, Jonathan Aning, the South West Prostate Dashboard collaborative

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Giving justice to listening: exploring the impact of a novel dialogical approach to mental wellbeing on healthcare staff by Isaac Nsiah, Cornelia Junghans, Cornelia Junghans, Henock B. Taddese, Anna Dentschuk, Amanda Bueno de Mesquita, Matthew Ball

“…We used self-determination theory and transformational learning theory as guiding conceptual frameworks. …”
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evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomat... by Jeffrey L. Cummings, Alireza Atri, Howard H. Feldman, Oskar Hansson, Mary Sano, Filip K. Knop, Peter Johannsen, Teresa León, Philip Scheltens

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