Impact of COVID-19 on the epidemiological situation of cervical cancer in Irkutsk region and Irkutsk city (2010–2020) by L. D. Zhuykova, O. A. Ananina, L. V. Pikalova, G. A. Kononova, A. A. Kalichkin

“…The effectiveness of early diagnosis (active and early detection) increased significantly from 2010 to 2019; however, it became lower in 2020, due to transformation of many inpatient settings into COVID-19 hospitals and restrictive measures for preventive medical examination. …”
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Adaptation Relationship Between Water Resource Utilization and Economic Development in Jiangxi Province by Wang Fei, Mu Yaqing, Tian Pei, Hao Fanghua, Chen Shu, Wu Yijin

“…[Methods] Industrial water consumption and industrial GDP data were used with the Tapio model in this study. …”
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Bridging the Gap: Improving Acute Ischemic Stroke Outcomes with Intravenous Thrombolysis Prior to Mechanical Thrombectomy by Jessica Seetge, Balázs Cséke, Zsófia Nozomi Karádi, Edit Bosnyák, László Szapáry

“…Multivariate analysis revealed that IVT was independently associated with favorable functional outcomes (<i>p</i> = 0.011) and reduced mortality (<i>p</i> = 0.021). No significant differences were observed in terms of clinical improvement at 72 h, successful recanalization, thrombus migration, or hemorrhagic transformation between the groups. …”
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Surgeons Knowledge, Attitude, and Practice Toward Preoperative Inflammatory Bowel Disease Medications and Post-Operative Complications by Alhassan N, Alnwdel AN, Beyari MB, Aldeligan SH, Alhassan R, Abdulla MH, Bin Traiki T

“…Noura Alhassan,1 Abdullah Nasser Alnwdel,2 Mohammed Basem Beyari,3 Saleh Husam Aldeligan,3 Reem Alhassan,4 Maha Hamadien Abdulla,1 Thamer Bin Traiki1 1Colorectal Research Chair, Department of Surgery, College of Medicine, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia; 2Colorectal Surgery, Department of Surgery, King Fahad Specialist Hospital, Buraydah, Saudi Arabia; 3College of Medicine, King Saud University, Riyadh, Saudi Arabia; 4Pharmacy Department, Prince Sultan Military Medical City, Riyadh, Saudi ArabiaCorrespondence: Mohammed Basem Beyari, Email Mohammedbeyari44@gmail.comBackground: Biologics, particularly anti-TNF agents, have transformed the management of inflammatory bowel disease (IBD), but concerns about their perioperative safety persist.Objective: This study evaluates the knowledge, attitudes, and practices of surgeons in Saudi Arabia regarding the preoperative management of IBD patients undergoing surgery while on biological treatments.Methods: A cross-sectional survey was conducted among 115 surgeons. …”
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Prognosis of Patients with Hepatocellular Carcinoma Treated with TACE: A New Score Combining Alpha-Fetoprotein and Des-&gamma;-Carboxy Prothrombin by Lu SY, Sun HY, Zhou Y, Luo X, Liu S, Zhou WZ, Shi HB, Yang W, Tian W

“…Serum AFP and DCP levels were log-transformed to construct the AD score. Multivariate Cox regression analysis on cirrhosis subgroups validated the objectivity of the model. …”
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Assessment of the attitude and fears of the physicians of Pakistan regarding artificial intelligence: a cross-sectional survey in 2024 by Abdur Rehman Khalid, Farooq Ahmad, Smak Ahmed, Muhammad Ahrar Bin Naeem, Noor ul Ain, Hassan Mehmood, Aasma Sajawal, Muhammad Umar, Aiman Atta, Hassaan Amin, Shahid Mahmood

“…Abstract Background and aim Artificial intelligence has emerged as a transformative tool in healthcare, enhancing diagnostic accuracy, advancing genetic studies, and improving personalized medicine by reducing human error. …”
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Effect of probiotic strains, L-arginine and carvedilol on myocardial infarction size in systemic inflammation in rats by Yu. Yu. Borshchev, S. M. Minasyan, I. Yu. Burovenko, E. S. Protsak, V. Yu. Borshchev, O. V. Borshcheva, M. M. Galagudza

“…Hemodynamic parameters in isolated heart did not differ between the groups. The concentration of proinflammatory cytokines and transforming growth factor-β in plasma was significantly higher in the SIRS group than in the control. …”
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ERADICATION OF HCV INFECTION IN PATIENTS WITH LIVER CIRRHOSIS: FACTOR OF CANCER PREVENTION OR CARCINOGENESIS? by N. A. Malinina, N. V. Mazurchik, O. I. Tarasova, P. P. Ogurtsov

“…However, the risk of transformation of liver cirrhosis into hepatocellular carcinoma is still high even after complete eradication of the virus. …”
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A possible role for immunogenetic factors in myositis developing after vaccination in the pre-covid-19 era by Eaman Alhassan, Anna Patnaik, Anna Patnaik, Ejaz A. Shamim, Ejaz A. Shamim, Ejaz A. Shamim, Janardan P. Pandey, Lisa G. Rider, Frederick W. Miller, Frederick W. Miller

“…IntroductionVaccinations have had a transformative impact on public health, reducing the incidence of many infectious diseases and increasing survival. …”
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INTERNATIONAL FORUM “OLD AND NEW MEDIA: ALONG THE PATH TOWARDS A NEW AESTHETICS” / МЕЖДУНАРОДНЫЙ ФОРУМ «СТАРЫЕ И НОВЫЕ МЕДИА: ПУТИ К НОВОЙ ЭСТЕТИКЕ»... by BOGATYRYOVA ELENA A.

“…Notice was made of alarming tendencies of transforming consciousness into that of “gamers,” reacting in correlations with certain algorithms, and a transference from discourse and substantiations towards reactions and evaluations. …”
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Risk factors of human papillomavirus-related cervical lesions in postmenopausal women: a cross-sectional study by Hongmin Zeng, Qianling Dai, Jieru Peng, Juan Li, Jing Chen, Zhipeng Lan, Xia Wu, Ting Shu, Liu Yang, Wenyi Lin, Mulan Li, Xiao Yang, Yonghong Lin

“…Multivariate analysis revealed that factors showing significant differences between two categories included co-infection with types 16 and 18 (adjusted odds ratio [aOR] = 0.348, 95% confidence interval [CI] = 0.138–0.881, p = 0.026), mixed infections involving other types, HPV 16/18 (aOR = 0.514, 95% CI = 0.336–0.785, p = 0.002), transformation zone (TZ) 3 (aOR = 1.604, 95% CI = 1.018–2.528, p = 0.041), and colposcopy impressions indicating high-grade features and worse (aOR = 11.846, 95% CI = 2.132–65.807, p = 0.005). …”
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Key events in the process of sex determination and differentiation in early chicken embryos by Xiaoqian Lv, Changhua Sun, Xin Liu, Guanzheng Liu, Wei Gong, Hongwu Qian, Zeyu Li, Jun Wu, Xilin Zhu, Jiuzhou Song, Yingjie Niu, Hongyan Sun, Wei Han, Guo hong Chen, Kai Jin, Bichun Li, Qisheng Zuo

“…This approach aims to unravel key regulatory mechanisms and advance developmental biology insights. Methods We analyzed molecular mechanisms of chicken sex determination at key stages (E0 blastocysts, E3.5-E6.5 genital ridges, E18.5 gonads) using RNA sequencing. …”
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Phytotea “ATINE” enhances the immunomodulatory effect of adaptogenic factors of the Truskavets’ Spa in patients after radical treatment of oncological pathology by Igor Bombushkar, Mykhaylo Korda, Anatoliy Gozhenko, Ivan Savytskyi, Oleksandr Chebanenko, Nataliya Badiuk, Walery Zukow, Anatoliy Anchev, Viktor Duzhar, Dariya Popovych, Igor Popovych

“…The state of cellular, humoral and phagocytic links of immunity was assessed using routine methods, and two equal groups were formed on this basis. …”
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Hypovitaminosis D in patients with oral leukoplakia: insights from a cross-sectional study by Andrea Maturana-Ramirez, Andrea Maturana-Ramirez, Juan Aitken-Saavedra, Dante Mora-Ferraro, Gabriel Rojas-Zúñiga, Iris Espinoza-Santander, Gonzalo Rojas-Alcayaga, Ana Ortega-Pinto, Montserrat Reyes, Diego Lazo, Egardo Caamanão

“…The present study aims to compare serum vitamin D levels between patients with and without oral leukoplakia, by smoking habit.MethodsThis cross-sectional study involved a group of 45 cases with oral leukoplakia and a control group with 45 individuals. …”
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Experience in the use of neutralizing monoclonal antibodies in kidney transplant recipients with COVID-19 by I. G. Kim, M. A. Lysenko, N. F. Frolova, L. Yu. Artyukhina, T. A. Buruleva, A. M. Nikitina, V. E. Vinogradov, E. V. Volodina, V. I. Chervinko, E. V. Kryukov, M. L. Zubkin

“…In group 1, after the use of mAb, progression of pulmonary process was observed less frequently than in the control group with CT1-2 transformation to CT3-4 (9.1% vs. 30.3%, respectively, p &lt; 0.01). …”
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Single-cell sequencing unveils the transcriptomic landscape of castration-resistant prostate cancer-associated fibroblasts and their association with prognosis and immunotherapy re... by Yifeng Qiu, Yuhan Wang, Jiahe Liu, Kai Sun, Baohua Liu, Qi Hou

“…Abstract Background The tumor microenvironment (TME) is increasingly acknowledged as a determinant in the malignant transformation and progression of castration-resistant prostate cancer (CRPC). …”
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In vitro investigation of flower-like micro-nano topography modifications to improve titanium implant surface properties by Nadia Kartikasari, Ratri Maya Sitalaksmi, Karina Mundiratri, Salsabila Eliya Andaru, Aisyah Rachmadani Putri Gofur, Harry Laksono

“…Results: The MN group significantly transformed titanium surfaces into a micro-nano flower-like topography with hydroxyl and sodium titanate structures. …”
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Marked mucosal lipid shifts in treatment refractory inflammatory bowel disease: a lipidomic study by Øystein K. Moe, Qian Gao, Dawei Geng, Einar Jensen, Rasmus Goll, Oddmund Nestegard, Mona D. Gundersen, Jon R. Florholmen, T. Moritz

“…Lipidomics data were log2-transformed and auto-scaled before analysis. P-values were adjusted using Benjamini- Hochberg procedure to control the false discovery rate (FDR). …”
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Independent and joint associations of neighbourhood greenness and walkability with transportational and recreational physical activity among youth and adults in Canada by Natalie Doan, Sebastian A. Srugo, Stephanie A. Prince, Rachel C. Colley, Daniel G. Rainham, Taru Manyanga, Gregory P. Butler, Richard Larouche, Sarah E. Turner, Justin J. Lang

“…To derive an indicator of neighbourhood greenness, for each survey year, we aggregated mean Normalized Difference Vegetation Index (NDVI) values within 2016 dissemination areas. …”
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TCR and BCR repertoire analysis reveals distinct signatures between benign and malignant ovarian tumors by Zhonghuang Wang, Zhonghuang Wang, Zhe Zhang, Dongli Zhao, Dongli Zhao, Zhenglin Du, Bixia Tang, Enhui Jin, Hailong Kang, Wenming Zhao, Yuanguang Meng

“…Among them, the adaptive immune system is a crucial component of the immune system, as it is responsible for generating and modulating the immune repertoire, which is vital for immune responses.MethodsWe conducted a comprehensive analysis of T cell receptor (TCR) and B cell receptor (BCR) clonotypes in the peripheral blood immune repertoire of 20 patients with benign and malignant ovarian tumors. …”
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