Peripheral Blood T‐Cell Receptor Repertoire Diversity as a Potential Biomarker in the Diagnosis and Treatment Evaluation of Colorectal and Lung Cancers: A Prospective Observational... by Jilong Ma, Yuanbiao Wang, Zhixin Zhang, Xinyi Cai, Xudong Xiang, Yan Chen, Fengqiong Sun, Jian Dong

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Focus on reflective competence: A triangulation to examine youth soccer coaches' reflective competence by Max Danner, Mareike Ahns, Günter Amesberger

“…Against this background, our study asks: What (breadth) and how (depth) do youth coaches reflect on their knowledge and coaching practice? Method Seven coaches from DFB selection centers in Bavaria participated in the study. …”
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Comparative efficacy and complication rates after local treatment for cervical intraepithelial neoplasia and stage 1a1 cervical cancer: protocol for a systematic review and network... by Orestis Efthimiou, Georgia Salanti, Huseyin Naci, Philip Bennett, Antonios Athanasiou, Areti Angeliki Veroniki, Ilkka Kalliala, Sarah Bowden, Maria Paraskevaidi, Pierre Martin-Hirsch, Evangelos Paraskevaidis, Maria Kyrgiou

“…We hereby describe a protocol of a systematic review and network meta-analysis that will update the evidence and compare all relevant treatments in terms of efficacy and complications.Methods and analysis Literature searches in electronic databases (CENTRAL, MEDLINE, EMBASE) or trial registries will identify published and unpublished randomised controlled trials (RCTs) and cohort studies comparing the efficacy and complications among different excisional and ablative techniques. …”
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Implementing large language model and retrieval augmented generation to extract geographic locations of illicit transnational kidney trade by Zifu Wang, Meng-Hao Li, Patrick Baxter, Olzhas Zhorayev, Jiaxin Wei, Valerie Kovacs, Qiuhan Zhao, Chaowei Yang, Naoru Koizumi

“…., offering buyer, seller, broker and/or surgery) that each country played. Methods This study employed state-of-the-art technologies, including Bidirectional Encoder Representations from Transformers (BERT) and Generative Pre-Trained Transformers (GPT) model Llama3.3 from Meta in developing a kidney trade country database. …”
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Prediction of PD-L1 tumor positive score in lung squamous cell carcinoma with H&E staining images and deep learning by Qiushi Wang, Xixiang Deng, Pan Huang, Qiang Ma, Lianhua Zhao, Yangyang Feng, Yiying Wang, Yuan Zhao, Yan Chen, Peng Zhong, Peng He, Mingrui Ma, Peng Feng, Hualiang Xiao

“…BackgroundDetecting programmed death ligand 1 (PD-L1) expression based on immunohistochemical (IHC) staining is an important guide for the treatment of lung cancer with immune checkpoint inhibitors. However, this method has problems such as high staining costs, tumor heterogeneity, and subjective differences among pathologists. …”
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Technological Education and Engineering Pedagogy by D. P. Danilaev, N. N. Malivanov

“…The authors believe that the present research could be useful for the development of alternative methods and forms of training of vocational and pedagogical personnel.…”
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Characterising the outcomes, impacts and implementation challenges of advanced clinical practice roles in the UK: a scoping review by Catrin Evans, Jeanette Eldridge, Roger Knaggs, Paul Hendrick, Peter Harris, Brenda Poku, Ruth Pearce, John McLuskey, Philippa Tomczak, Ruaridh Thow, Joy Conway, Richard Collier, Gowsika Yogeswaran

“…Objectives In response to demographic and health system pressures, the development of non-medical advanced clinical practice (ACP) roles is a key component of National Health Service workforce transformation policy in the UK. This review was undertaken to establish a baseline of evidence on ACP roles and their outcomes, impacts and implementation challenges across the UK.Design A scoping review was undertaken following JBI methodological guidance.Methods 13 online databases (Medline, CINAHL, ASSIA, Embase, HMIC, AMED, Amber, OT seeker, PsycINFO, PEDro, SportDiscus, Osteopathic Research and PenNutrition) and grey literature sources were searched from 2005 to 2020. …”
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Application of Multidisciplinary Diagnosis and Treatment (MDT) clinical teaching model in the clinical teaching of some undergraduates of breast diseases in surgery by Nan Wang, Lin Li, Luhong Han, Shan Jiang, Youyi Xiong, Fang Wang, Yuanting Gu, Xinxing Wang

“…Contemporary clinical teaching faces challenges with traditional methods unable to address students' theoretical strength and practical limitations. …”
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Effects of an urban cable car intervention on quality of life: an observational, quasi-experimental study in Bogotá, Colombia (TrUST)Research in context by Laura Baldovino-Chiquillo, Olga L. Sarmiento, Donny S. Pasos, Leonardo Palencia-Pérez, Gary O'Donovan, Victor Cantillo-Garcia, Lina Martínez, Julian Arellana, Luis A. Guzman

“…The aim was to assess the effects of the TransMiCable cable car intervention on quality of life in males and females in a low-income settlement in Bogotá, Colombia. Methods: The Urban Transformations and Health (TrUST) natural experiment was conducted between 2018 and 2020 in intervention and control neighbourhoods. …”
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Neuropsychiatric manifestations following chimeric antigen receptor T cell therapy for cancer: a systematic review of clinical outcomes and management strategies by Max Topp, Michael Hudecek, Hermann Einsele, Imad Maatouk, Leo Rasche, Johannes Duell, Anna Fleischer, Sophia Kurth, Patrick-Pascal Strunz, Julia Mersi, Carmen Sanges

“…Background Chimeric antigen receptor (CAR)-T cell therapy has emerged as a transformative modality in the treatment of patients with cancer. …”
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Association of atherogenic index of plasma with kidney dysfunction in diabetic individuals: findings from two national population-based studies by Lingling Zhu, Tiansu Lv, Siyuan Song, Ying Tan, Yun She, Xiqiao Zhou, Jiangyi Yu, Qianhua Yan

“…This study aims to clarify the association of AIP with kidney dysfunction in diabetic individuals. Methods This cross-sectional study analyzed a representative sample of participants aged 20 years and older from the United States (n = 2,386, NHANES 2007–2018) and Korea (n = 698, KNHANES 2012). …”
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THE LEXICON OF CONTEMPORARY WAR TIME: COMPRESSIVE PROFESSIONAL SLANG UNITS IN THE UKRAINIAN LANGUAGE by Oleksandr S. Ivko, Natalia V. Diachok

“…We have utilized the dis- tributive analysis approach to determine the types of nominative units’ transformation. Military discourse is the field of language functioning that fosters the production of neologisms emerging as a result of different types of compression. …”
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Immune regulatory genes impact the hot/cold tumor microenvironment, affecting cancer treatment and patient outcomes by Mengmeng Sang, Jia Ge, Juan Ge, Juan Ge, Gu Tang, Qiwen Wang, Jiarun Wu, Liming Mao, Liming Mao, Xiaoling Ding, Xiaorong Zhou

“…Nevertheless, as yet there is no consensus regarding the clinically relevant definition of hot/cold tumors, and the influence of immune genes on the formation of hot/cold tumors remains poorly understood.MethodsData for 33 different types of cancer were obtained from The Cancer Genome Atlas database, and their immune composition was assessed using the CIBERSORT algorithm. …”
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Effects of Recreational Football on Bone Mineral Density and Isokinetic Muscle Strength in Elderly Men: A Study of Turkish Older Men by Cemal Polat, Alparslan Unveren, Hayri Ertan, Gian Mario Migliaccio, Zarife Pancar, Luca Russo

“…<i>Material and Methods</i>: A total of 57 elderly men (65.5 ± 2.7 years) were randomly divided into a football group (FG; <i>n</i> = 28) and a control group (CG; <i>n</i> = 29). …”
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Fertility intention and its correlates with reproductive-aged married women in Ethiopia: an adapted theory of planned behavior (TPB) by Fitsum Tariku Fantaye, Solomon Abrha Damtew, Kelemua Menegesha Sene

“…Abstract Background In Ethiopia, despite different attempts to manage rapid population growth and reduce the average number of births per woman, the expected changes outlined in the National Health Sector Transformation Plan (HSTP II) and Reproductive health (RH 2015 2020) strategies have not been fully realized over the past decade. …”
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Evaluating and comparing the effects of paracetamol and ibuprofen on wound healing, MMP-9, and TGF-β1 levels in patients following upper third molar tooth extraction by Sumatee Yuthavong, Piyanart Chatiketu, Onsaya Keadto, Pattaranee Srichairatanakool, Somdet Srichairatanakool, Vuttinun Chatupos

“…Salivary matrix metalloproteinase 9 (MMP-9) and transforming growth factor beta1 (TGF-β1) concentrations were used as proinflammatory indicators. …”
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An analytical approach towards attaining leave no one behind using patterns and distributions of inequalities in antenatal and facility delivery coverage in Uttar Pradesh, India by Vasanthakumar Namasivayam, Ravi Prakash, Bidyadhar Dehury, Shajy Isac, Fernando C. Wehrmeister, Marissa Becker, James Blanchard, Ties Boerma

“…Abstract Background Leave No One Behind (LNOB) is a central, transformative promise of the 2030 Agenda for Sustainable Development Goals. …”
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The Effect of Hydrogen Peroxide on Biogas and Methane Produced from Batch Mesophilic Anaerobic Digestion of Spent Coffee Grounds by Siham Sayoud, Kerroum Derbal, Antonio Panico, Ludovico Pontoni, Massimiliano Fabbricino, Francesco Pirozzi, Abderrezzaq Benalia

“…This paper aims to explore both experimental and modeling anaerobic digestion (AD) processes as innovative methods for managing the substantial quantities of spent coffee grounds (SCG) generated in Algeria, transforming them into valuable renewable energy sources (biogas/methane). …”
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Serum TGF-β1 and CD14 Predicts Response to Anti-TNF-α Therapy in IBD by Stepan Coufal, Miloslav Kverka, Jakub Kreisinger, Tomas Thon, Filip Rob, Martin Kolar, Zuzana Reiss, Dagmar Schierova, Klara Kostovcikova, Radka Roubalova, Lukas Bajer, Zuzana Jackova, Martin Mihula, Pavel Drastich, Jana Tresnak Hercogova, Michaela Novakova, Martin Vasatko, Milan Lukas, Helena Tlaskalova-Hogenova, Zuzana Jiraskova Zakostelska

“…However, approximately every third IBD patient does not respond to this therapy in the long term, which delays efficient control of the intestinal inflammation. Methods. We analyzed the power of serum biomarkers to predict the failure of anti-TNF-α. …”
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The interaction network and potential clinical effectiveness of dimensional psychopathology phenotyping based on EMR: a Bayesian network approach by Jianqing Qiu, Ting Zhu, Ke Qin, Wei Zhang

“…The Research Domain Criteria (RDoC) framework serves as a recognized approach to addressing this heterogeneity, and several assessment and translation techniques have been proposed. Among these methods, transforming RDoC scores from electronic medical records (EMR) using Natural Language Processing (NLP) has emerged as a suitable technique, demonstrating clinical effectiveness. …”
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