Decoding Digital Discourse Through Multimodal Text and Image Machine Learning Models to Classify Sentiment and Detect Hate Speech in Race- and Lesbian, Gay, Bisexual, Transgender,... by Thu T Nguyen, Xiaohe Yue, Heran Mane, Kyle Seelman, Penchala Sai Priya Mullaputi, Elizabeth Dennard, Amrutha S Alibilli, Junaid S Merchant, Shaniece Criss, Yulin Hswen, Quynh C Nguyen

“…ResultsOur findings highlighted key differences in model performance. Among unimodal models, Bidirectional Encoder Representations from Transformer outperformed Visual Geometry Group 16, achieving higher accuracy and macro–F1-scores across all tasks. …”
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Prenatal exposure to phthalates and preschool children’s intellectual scores: Effect modification by child sex by Carly V. Goodman, Christine Till, Sietske Berghuis, Joseph M. Braun, Gina Muckle, Aimin Chen, Youssef Oulhote, Bruce Lanphear, Jillian Ashley-Martin, Tye E. Arbuckle

“…Objectives: We examined associations between gestational phthalate metabolites and intelligence at ages 3–4 and investigated effect modification by child sex. Methods: We analyzed data from 511 mother–child pairs enrolled in the Maternal-Infant Research on Environmental Chemicals study. …”
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Role of CDH1 gene variants and E-cadherin localization in gastric mucosal cancerization by Yunbo Wu, Yunzhan Zhang, Yunkai Dai, Qi Luo, Shaoyang Lan, Xu Chen, Weijing Chen, Ruliu Li, Ling Hu

“…BackgroundThis study investigates the role of CDH1 gene single nucleotide polymorphisms (SNPs), mRNA transcription levels, and E-cadherin protein localization in Helicobacter pylori (Hp)-associated gastric diseases and their contribution to gastric mucosal carcinogenesis.MethodsGastric mucosal samples were analyzed for histopathology (Hematoxylin-Eosin staining) and Hp detection (rapid urease test, Giemsa staining). …”
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Guidelines and variations in patterns of GnRH analogue use in castration-resistant prostate cancer across six countries by G. George, D. Enting, H. Garmo, P. Stattin, I.F. Lissbrant, M. Monroy-Iglesias, L.-M. Scailteux, F. Balusson, C. Van Praet, N. Lumen, G. Marvaso, G. Corrao, B.A. Jereczek-Fossa, L. Chehade, A. Shamseddine, M. Charafeddine, M. Van Hemelrijck

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Beliefs and perceptions of genetic testing by clinical, demographic, and health characteristics: A U.S.-based study utilizing the health information national trends (HINTS) survey by Pranali G. Patel, Marvin E. Langston, Justin X. Moore, Yunan Han, Marquita W. Lewis-Thames, Lindsay Fuzzell, Saira Khan

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Impact of a multi-component implementation strategy to increase outdoor free play opportunities in early childhood education and care (ECEC) services: the get outside get active (G... by Sze Lin Yoong, Nicole Pearson, Luke Giles, Hannah Lamont, Luke Wolfenden, Jannah Jones, Christophe Lecathelinais, Patti-Jean Naylor, Anthony Okely, Nicole Nathan, Kathryn Reilly, Rebecca Lorch, John Wiggers, Jacklyn Jackson, Melanie Lum, Karen Gillham, Alice Grady

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Accuracy of a novel calibratable real-time continuous glucose monitoring device based on FreeStyle libre in- and out-of-hospital by Zhenghao Wu, Zhenghao Wu, Zhaoxiang Liu, Wenhui Zhao, Shaocheng Wang, Liangbiao Gu, Jianzhong Xiao

“…This study aim to validate the consistency and clinical accuracy of the product by comparing the capillary blood glucose (CBG) with CGM data in both in-hospital and outpatient scenarios.MethodsResults of CGM devices were compared with random capillary glucose values from users in both in-hospital and outpatient settings. …”
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CILO-CLOP Trial: Cilostazol Versus Clopidogrel in Acute Moderate and Moderate-to-Severe Ischemic Stroke: A Randomized Controlled Multicenter Trial by Mohamed G. Zeinhom, Mohamed Ismaiel, Mohamed Fouad Elsayed Khalil, Mohamed Ahmed Almoataz, Tarek Youssif Omar, Ahmed Mohamed Ali Daabis, Hossam Mohamed Refat, Ahmed Ahmed Mohamed Kamal Ebied, Noha Abdelwahed, Ahmed Zaki Omar Akl, Emad Labib Abdelhamid Mahmoud, Salah Ibrahim Ahmed, Sherihan Rezk Ahmed

“…Accordingly, in this study we assess the role of cilostazol as an alternative to clopidogrel in Egyptian patients with first-ever non-cardioembolic moderate or moderate-to-severe ischemic stroke. Methods A total of 870 patients with moderate and moderate-to-severe acute ischemic stroke (AIS) were randomly assigned to administration of loading and maintenance doses of cilostazol or clopidogrel. …”
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Meta-analyses of the effects of high-intensity interval training in elite athletes — part II: relationships between the mean effects on various performance measures by Hans-Peter Wiesinger, Hans-Peter Wiesinger, Hans-Peter Wiesinger, Will G. Hopkins, Nils Haller, Nils Haller, Julia Blumkaitis, Tilmann Strepp, Thomas Leonhard Stöggl, Thomas Leonhard Stöggl

“…Here, we extend the analyses to relationships between mean changes of these measures and consider implications for understanding and improving HIIT that were not apparent in the previous analyses.MethodsThe data were mean changes from HIIT with highly trained endurance and elite other (mainly team sport) athletes in studies where two or more measures or predictors of performance were available. …”
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Identification of patient endotypes and adalimumab treatment responders in axial spondyloarthritis using blood-derived extracellular matrix biomarkers by Anne Gitte Loft, Inge Juul Sørensen, Mikkel Østergaard, Susanne J Pedersen, Morten Asser Karsdal, Ole Rintek Madsen, Anne-C Bay-Jensen, Peder Frederiksen, Signe Holm Nielsen, Helena Port, Frederik Christiansen, Sengul Seven

“…Objective To explore the potential of a panel of ECM remodelling markers as endotyping tools for axial spondyloarthritis (axSpA) by separating patients into subtypes and investigate how they differ among each other in disease activity scores and response to treatment with adalimumab.Methods In three axSpA studies, a panel of 14 blood-based ECM biomarkers related to formation of collagen (PRO-C2, PRO-C3, PRO-C6), degradation of collagen by metalloproteinases (C1M, C2M, T2CM, C3M, C4M, C6M, C10C), matrix metalloproteinase (MMP)-degraded prolargin (PROM), MMP-degraded and citrullinated vimentin (VICM), basement membrane turnover (PRO-C4) and neutrophil activity (CPa9-HNE) were assessed to enable patient clustering (endotyping). …”
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The Palatability Dance—SNPs and Genetic Taste Scores of Umami, Sweet, and Bitter Taste Receptors (TAS1R and TAS2R Genes) by Jean Leite, Jaqueline Pereira, Marcelo Rogero, Regina Fisberg, Flávia Sarti

“…Considering the limited knowledge of these associations in the context of admixed groups, like the Brazilian population, we aimed to investigate associations of SNPs in the TAS1R and TAS2R taste receptor gene families with diet quality. Methods: A sample of 901 individuals ≥ 12 years old from the general population, categorized into age groups (adolescents, adults, and elderly), was interviewed in the Health Survey of Sao Paulo (ISA-Capital). …”
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Abstract 229: Recanalization Rate in Mechanical Thrombectomy in Patients With Elevated LDL‐C Levels by Xiaoyi Gao, Kara Christopher, Wilson Rodriguez, Weston Gordon, Guillermo Linares

“…We also aim to investigate whether LDL‐C levels affect MT recanalization rate. Methods We reviewed the records of 223 patients who received MT at our institution from 2018‐2023. …”
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Multicentre assessment of transperineal targeted prostate biopsy performed as part of a targeted and systematic biopsy diagnostic strategy in men without previous prostate biopsies by Mohammed Sheweita, Liam Blaney, Jon Oxley, Douglas Kopcke, Stefanos Bolomytis, Paul Burn, Adrian Andreou, Jon Heron, Raj Persad, Nick Burns‐Cox, Jonathan Aning, the South West Prostate Dashboard collaborative

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Giving justice to listening: exploring the impact of a novel dialogical approach to mental wellbeing on healthcare staff by Isaac Nsiah, Cornelia Junghans, Cornelia Junghans, Henock B. Taddese, Anna Dentschuk, Amanda Bueno de Mesquita, Matthew Ball

“…We used self-determination theory and transformational learning theory as guiding conceptual frameworks. …”
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evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomat... by Jeffrey L. Cummings, Alireza Atri, Howard H. Feldman, Oskar Hansson, Mary Sano, Filip K. Knop, Peter Johannsen, Teresa León, Philip Scheltens

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Ultra-processed food consumption in the central division of Fiji by Aliyah Palu, Joseph Alvin Santos, Daisy Coyle, Maria Shahid, Juliette Crowther, Gade Waqa, Colin Bell, Jacqui Webster, Briar McKenzie

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Patient-Reported Outcomes by Baseline Body Surface Area Involvement Among Individuals Initiating Biologic Therapy: Results from the CorEvitas Psoriasis Registry by April W. Armstrong, Steven R. Feldman, Timothy Fitzgerald, Theodore Alkousakis, Adam Sima, Alvin Li, Hyung-Joo Kang, Sandra I. Main, Saakshi Khattri, Linda Stein Gold

“…Overlap between BSA groups for each outcome was calculated via non-parametric Mann–Whitney statistic transformation (range 0.0–1.0; 0.5 indicates complete similarity [i.e., for a comparison between low and high BSA groups, overlap of 0.5 means there is 50% probability that a randomly selected patient with low BSA would have the same or greater PRO burden as one with high BSA]; 0 or 1 indicates complete dissimilarity) to determine whether each measure differed in randomly selected patients with low or medium versus high BSA. …”
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The interlinked trajectories of interpersonal attachment and maladaptive behaviors among Chinese adolescents—a latent growth modeling approach by He Xiao, Pei Chen, Huiyi Xiao, Peizhi Zhong, Jiajie He, Yangang Nie

“…Specifically, latent growth curve modeling was conducted to estimate the trajectories of the seven key constructs, with Wald tests assessing differences in growth factors across constructs. Slope correlations between attachment and maladaptive behaviors were examined, and Fisher’s z-transformation was applied to compare the strength of these slope-level associations. …”
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The Influence of Ming Dynasty Buddhism’s Chan Jing He Yi (Integration of Zen and Pure Land Buddhism 禪淨合一) on Buddhist Thought in <i>Journey to the West</i> by Ran Wei

“…The Buddhist ideas in these four works went through a transformation from advocating yoga theory 瑜伽論 to advocating belief in Vaisravana 毗沙門天王信仰 and then to focusing on the “mind nature 心性” theory of Zen Buddhism. …”
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Comparison of photodynamic therapy and LEEP in women of reproductive age with cervical squamous intraepithelial neoplasia 2 (CIN2): A prospective observational study in China by Cheng Li, Xuanhui Wang, Qiulin Cui, Mian He, Ming Chen

“…To compare the effectiveness of 5-ALA-PDT and loop electrosurgical excision procedure (LEEP) in patients with CIN2, we conducted this prospective cohort study in Chinese patients with CIN2. Methods: 229 patients with CIN2 were enrolled. They were divided into the PDT Group (n=94) and LEEP Group (n=135) according to the patient's willingness. …”
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