Cost-effectiveness of universal genetic screening for familial hypercholesterolemia in young adults aged 18–40 years in China by Rui Meng, Fenghao Shi, Baoming Zhang, Chao Li, Jinyan Wang, Lingqin Song, Lei Zhang, Mingwang Shen

“…This study aims to evaluate the cost-effectiveness of universal genetic screening of young adults aged 18–40 years compared to universal cholesterol screening or current passive screening strategies (opportunistic cholesterol screening and genetic cascade testing) for FH in China. Methods A decision-analytic Markov model was constructed to simulate the lifetime (until 100 years old or 99% of patients died) coronary heart disease (CHD) events, discounted costs, gains in quality-adjusted life years (QALYs), and incremental cost-effectiveness ratios (ICERs) of different screening strategies. …”
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Predicting IDH and 1p/19q molecular status of gliomas with multi-b values DWI by Shanshan Zhao, Peipei Wang, Eryuan Gao, Mengzhu Wang, Guang Yang, Shouhui Niu, Mengjiao Pan, Kai Zhao, Jingliang Cheng, Xiaoyue Ma

“…For predicting IDH status, CTRW_α exhibited the largest effect size and best diagnostic performance with an AUC of 0.761. At a threshold of 0.855, the sensitivity was 0.651, the specificity was 0.846, and the accuracy was 0.758. …”
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Performance of OncoE6TM Cervical Test in detecting cervical precancer lesions in HIV-positive women attending an HIV clinic in Bujumbura, Burundi: a cross-sectional study by Zacharie Ndizeye, Sonia Menon, Jean-Pierre Van Geertruyden, Catherine Sauvaget, Y Jacquemyn, John-Paul Bogers, Ina Benoy, Davy Vanden Broeck

“…OncoE6 sensitivity varied from poor to low with increasing disease severity (42.1%, 95% CI 19.9% to 64.3% at CIN2+ threshold; and 58.3%, 95% CI 30.4% to 86.2% at CIN3+ threshold). …”
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Association between lactate-to-albumin ratio and mortality in hepatic failure: a retrospective cohort study by Huan Wu, Long Wu, Li Luo, Hai-yang Li, Bao-fang Zhang

“…A smooth curve fitting approach and threshold effect analysis were employed to detect the potentially non-linear relationship between the LAR and the risk of all-cause mortality in patients with hepatic failure. …”
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Reallocating 24-hour movement behaviors and its impact on mental health in preschool children: a compositional data and dose-response analysis by Tian Wang, Junyu Wang, Xuelin Lu, Xuhui Chen, Lanzhi Chen, Yixin Liang, DongQing Yang, Yanmei Shi, Rui Li, Yong Yang, Beibei Luo, Jie Zhuang

“…Methods In this cross-sectional study, 828 Chinese preschool children aged 3 to 6 years were assessed. …”
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Scraping Therapy Improved Muscle Regeneration through Regulating GLUT4/Glycolytic and AMPK/mTOR/4EBP1 Pathways in Rats with Lumbar Multifidus Injury by Bin Zou, Juan Du, Qiwen Xuan, Yajing Wang, Zixiao Wang, Wen Zhang, Lianghua Wang, Wei Gu

“…We then performed scraping therapy on the rats that had been randomly chosen and compared treatment effects at different time points. In vitro data including skin temperature and tactile allodynia threshold were collected and histological sections were analyzed. mRNA sequencing was applied to distinguish the genes or signaling pathways that had been altered due to scraping therapy, and the results were further verified through reverse transcription polymerase chain reaction and Western blot analysis. …”
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Adaptive Deeping Siamese Residual Network: A Novel Model for Few-Shot Bearing Fault Diagnosis by Yonghua Jiang, Maoli Lu, Zhilin Dong, Zhichao Jiang, Weidong Jiao, Chao Tang, Jianfeng Sun, Zhongyi Xuan

“…A novel Dynamic Time Warping (DTW) technique is applied to non-linearly adjust the sequence information, allowing for the precise calculation of the optimal match between two sequences by detecting subtle differences. Additionally, inspired by the concept of dynamic soft-hard threshold matching in unsupervised learning, an innovative strategy for dynamically adjusting the adaptive threshold has been developed to enhance the generalization capability of the proposed ADSRN. …”
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The effect of transcranial direct current stimulation on the treatment of patients with cervical myofascial pain syndrome by Farid Rezaei Moghaddam, Zohre Rozati, Afsane Dadarkhah, Kamran Azma, Siroos Azizi

“…Further investigation regarding comparison of tDCS and other methods is highly recommended on the treatment of myofascial pain syndrome.…”
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A monitoring and warning system for expressway slopes using FBG sensing technology by Yongqiang Hu, Chengyu Hong, Yifan Zhang, Guowei Li

“…The maximum magnitudes of cumulative strain and displacement in the present monitored expressway slope were 198 με and 5.06 mm, respectively. Critical threshold values of different warning levels for expressway slopes have been proposed using statistical analysis method based on comparative analysis of history monitored data from slopes in the same region. …”
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The Non-Orthogonal Multiple Access (NOMA) Dynamic Power Allocation in 5G Networks by Noor Alzubaidi, Ismael Sharhan Hubri

“… Abstract The thought of non-orthogonal multiple access (NOMA) are given as a potential radio access method for versatile correspondence networks past the fourth era (4G). …”
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The Experimental Investigation of the Development Potential of Low-Permeability Reservoirs in the Daqing Oilfield by Yazhou Zhou, Daiyin Yin

“…The throat radius distributions of the different low-permeability cores were determined by the constant velocity mercury injection method, the movable fluid distribution characteristics were determined by nuclear magnetic resonance, and the nonlinear fluid flow characteristics were analyzed via fluid flow experimentation. …”
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Cost-effectiveness analysis of influenza vaccination among the elderly in Qingdao city by Jinru LI, Jing JIA, Chunhui WANG, Zhaohai MENG, Xuezhao LU, Yu GAO, Kunzheng LYU

“…MethodsA Markov model was constructed to evaluate the cost-effectiveness of different influenza vaccination rates for influenza prevention. …”
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Optimal Cutoff Value of 1-Hour Postload Glucose to Identify Insulin Resistance in Women with Polycystic Ovary Syndrome by Sungwook Chun, Sihoon Lee

“…Categorization of patients based on the 1-h PG threshold showed significant differences for all laboratory variables related to insulin sensitivity/resistance, other than fasting insulin. …”
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Implementation of the 2022 AAP guidelines for neonatal hyperbilirubinemia could reduce the need for phototherapy in Italy by Carlo Dani, Monica Fusco, Marco Andreini, Giuseppe Pepe, Simone Pratesi

“…Total serum bilirubin (TSB) at the start of phototherapy, which was decided based on the guidelines of the Italian Society of Neonatology, was compared with the TSB thresholds recommended by AAP 2022 guidelines. Results Seven hundred and thirteen (82%) infants had TSB at the start of phototherapy lower than AAP 2022 threshold (16.2 ± 3.0 vs. 17.7 ± 3.4 mg/dL; P < 0.001) with a mean difference of 1.8 (0.7–2.6) mg/dL. …”
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Rat retinal function attenuation with IOP elevation is impacted by both blood pressure and intracranial pressure by Sera N. Ganearachchi, Anna K. van Koeverden, Christine T. O. Nguyen, Zheng He, Vickie H. Y. Wong, Bang V. Bui, Da Zhao

“…At each IOP level, ganglion retinal function was assessed using the electroretinogram.ResultsCompared with normal blood pressure groups, animals with high blood pressure had significantly smaller baseline ganglion cell-mediated scotopic threshold responses (STR). Animals with high ICP had larger scotopic threshold response (STR) amplitudes than the normal and low ICP groups. …”
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Towards high-quality development: The complex role of environmental regulation. by Jie Li, Xuguang Wang

“…Notably, the positive influence of environmental regulation on high-quality economic development is already evident at lower intensities, yet becomes markedly more pronounced when the regulatory intensity reaches or exceeds a certain threshold. Additionally, the paper delves into the heterogeneous impacts of environmental regulation on high-quality economic development across regions with differing pollution levels. …”
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The spectral features of EEG responses to transcranial magnetic stimulation of the primary motor cortex depend on the amplitude of the motor evoked potentials. by Matteo Fecchio, Andrea Pigorini, Angela Comanducci, Simone Sarasso, Silvia Casarotto, Isabella Premoli, Chiara-Camilla Derchi, Alice Mazza, Simone Russo, Federico Resta, Fabio Ferrarelli, Maurizio Mariotti, Ulf Ziemann, Marcello Massimini, Mario Rosanova

“…In experiment 2 we stimulated M1 at resting motor threshold in order to elicit MEPs characterized by a wide range of amplitudes. …”
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Temperature influences mood: evidence from 11 years of Baidu index data in Chinese provincial capitals by Mengjiao Yin, Mengmeng Zhu

“…Conversely, a 1°C increase in DTR led to decreases of 30.35%, 31.19%, and 15.41% in these indices (p &lt; 0.05). Threshold regression analysis revealed that the adverse effect of high temperatures on loneliness became insignificant when DTR exceeded 14°C. …”
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Unique environmental effects on physical activity participation: a twin study. by Glen E Duncan, Jack Goldberg, Carolyn Noonan, Anne Vernez Moudon, Philip Hurvitz, Dedra Buchwald

“…<h4>Methods</h4>Data were obtained from 1,389 twin pairs from the community-based University of Washington Twin Registry. …”
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Distance Measurement and Error Compensation of High-Speed Coaxial Rotor Blades Based on Coded Ultrasonic Ranging by Yaohuan Lu, Shan Zhang, Wenchuan Hu, Zhen Qiu, Zurong Qiu, Yongqiang Qiu

“…The time of flight (<i>Tof</i>) of coded ultrasonic ranging is calculated by the amplitude threshold improvement method and cross-correlation method, and the sound velocity is compensated by a proposed multi-factor compensation method. …”
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