Kappa Free Light Chains in Multiple Sclerosis as a Marker of Intrathecal Humoral Response: A Sex-Disaggregated Study by Raffaella Candeloro, Maila Galloppa, Laura Lombardo, Michele Laudisi, Sara Ghisellini, Giovanna Negri, Caterina Ferri, Carla Marcialis, Tiziana Bellini, Maura Pugliatti, Massimiliano Castellazzi

“…Conclusions: This study highlights the potential of KFLCs as a biomarker for MS but emphasises the need for sex-specific thresholds to improve diagnostic accuracy.…”
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Does the Relationship of the Autonomic Symptoms Questionnaire COMPASS 31 with Cardiovascular Autonomic Tests Differ between Type 1 and Type 2 Diabetes Mellitus? by Ilenia D’Ippolito, Marika Menduni, Cinzia D’Amato, Aikaterini Andreadi, Davide Lauro, Vincenza Spallone

“…Methods Seventy-nine participants with T1DM and 140 with T2DM completed COMPASS 31 before cardiovascular reflex tests (CARTs) for CAN, and assessment of symptoms, signs, vibration, and thermal perception thresholds for diabetic polyneuropathy (DPN) diagnosis. …”
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Longitudinal Model Shifts of Machine Learning–Based Clinical Risk Prediction Models: Evaluation Study of Multiple Use Cases Across Different Hospitals by Patricia Cabanillas Silva, Hong Sun, Mohamed Rezk, Diana M Roccaro-Waldmeyer, Janis Fliegenschmidt, Nikolai Hulde, Vera von Dossow, Laurent Meesseman, Kristof Depraetere, Joerg Stieg, Ralph Szymanowsky, Fried-Michael Dahlweid

“…Additionally, to investigate the clinical utility of our models, we performed decision curve analysis (DCA) and compared the results across the different years. A pairwise nonparametric statistical comparison showed no differences in the net benefit at the probability thresholds of interest (P>.05). …”
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High-Accuracy Robot Indoor Localization Scheme Based on Robot Operating System Using Visible Light Positioning by Weipeng Guan, Shihuan Chen, Shangsheng Wen, Zequn Tan, Hongzhan Song, Wenyuan Hou

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A novel method for measuring heat injury in leaves provides insights into the sequence of processes of heat injury development by Clara Bertel, Gilbert Neuner

“…The advantage of the DCS method is the precise, rapid and easy detection of heat thresholds. …”
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Mechanically deboned poultry meat and its role in rational and efficient use of raw materials by V. V. Gushchin

“…Nevertheless, the performed studies create conditions for improvement of the approach to classification of different MDPM types by the production method and maximum allowable threshold values of the main standardized parameters, assessment methods, detection of their characteristics and substantiation of terminology.…”
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Fixed-Time Distributed Event-Triggered Cooperative Guidance Methods for Multiple Vehicles with Limited Communications to Achieve Simultaneous Arrival by Zhenzhen Gu, Xugang Wang, Zhongyuan Wang

“…Aiming at the salvo-attack problem of multiple missiles, a distributed cooperative guidance law based on the event-triggered mechanism is proposed, which enables missiles with large differences in spatial location and velocity to achieve simultaneous attacks with only a few dozen information exchanges. …”
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Quality Control Technique for Ground-Based Lightning Detection Data Based on Multi-Source Data over China by Yongfang Xu, Yan Shen, Xiaowei Jiang, Fengyun Tian, Lei Cao, Nan Wang

“…Through experimental analysis of convective processes over different time periods, QC thresholds are established based on the CREF, TBB, and area ratio. …”
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Severe interstitial lung disease risk prediction in anti-melanoma differentiation-associated protein 5 positive dermatomyositis: the STRAD-Ro52 model by Fei Xiao, Feilong Chen, DongSheng Li, Songyuan Zheng, Xiao Liang, Juan Wu, JunYuan Zhong, Xiangliang Tan, Rui Chen, Junqing Zhu, Shixian Chen, Juan Li

“…This study quantitatively analysed chest high-resolution computed tomography (HRCT) images to assess MDA5+DM-ILD and establish a risk prediction model for severe ILD within six months.Methods We developed a ‘Standardized Threshold Ratio Analysis & Distribution’ (STRAD) to analyse lung HRCT images. …”
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Large inter-stock differences in catch size-at-age of mature Atlantic salmon observed by using genetic individual origin assignment from catch data. by Marja-Liisa Koljonen, Michele Masuda, Irma Kallio-Nyberg, Jarmo Koskiniemi, Irma Saloniemi

“…The Bayesian mixture model yielded slightly more conservative estimates than the direct probability method, threshold method, or the modified probability method. …”
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Evaluation of the effect of new generation denture base materials aged in artificial saliva at different pH levels on surface roughness and Candida albicans adhesion by Ezgi Arslan, Canan Akay, Demet Erdönmez, Esra Nur Avukat

“…Abstract Purpose The aim of this in vitro study was to evaluate the surface roughness and Candida albicans (C. albicans) biofilm formation of conventional heat-cured and different CAD/CAM milling denture base materials, after immersion in different pH levels of artificial saliva. …”
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Stability and Global Sensitivity Analysis for an Agree-Disagree Model: Partial Rank Correlation Coefficient and Latin Hypercube Sampling Methods by Sara Bidah, Omar Zakary, Mostafa Rachik

“…We first present the model and its different compartments. Then, we use the next-generation matrix method to compute thresholds of equilibrium stability. …”
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Multi-arm Cost-Effectiveness Analysis (CEA) comparing different durations of adjuvant trastuzumab in early breast cancer, from the English NHS payer perspective. by Caroline S Clarke, Rachael M Hunter, Ian Shemilt, Victoria Serra-Sastre

“…We present here a multi-arm joint analysis examining the relative cost-effectiveness of different durations of adjuvant trastuzumab.<h4>Methods and findings</h4>Network meta-analysis (NMA) was used to examine which trials' data to include in the cost-effectiveness analysis (CEA). …”
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Association of gestational diabetes mellitus diagnosed at different time points in oral glucose tolerance test with adverse pregnancy outcomes: a retrospective cohort study by Ruipeng Lin, Yulong Zhang, Yuxin Lin, Lili Yang, Jiayi Chen, Qingxiu Li, Haibo Li, Qian Zhang

“…BackgroundThis study aims to explore the association between gestational diabetes mellitus (GDM) diagnosed at different time points in the oral glucose tolerance test (OGTT) and adverse pregnancy outcomes (APO).MethodsA retrospective cohort study based on the 75g OGTT conducted in Fujian Maternity and Child Health Hospital. …”
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Association between the triglyceride glucose-waist circumference index and cardiovascular disease across different glycemic statuses among middle-aged and older Chinese adults by Yuyu Cui, Zhening Xu, Lijuan Ding, Yanju Li, Xiaoyan Zhou, Lingxia Li

“…IntroductionThis study aims to systematically investigate the association between the triglyceride-glucose index multiplied by waist circumference (TyG-WC) and the risk of cardiovascular disease (CVD) and further explore how this relationship varies across different glycemic statuses, including normal glucose regulation (NGR), prediabetes (Pre-DM), and diabetes mellitus (DM).MethodsData were obtained from the China Health and Retirement Longitudinal Study (CHARLS), including a total of 7,812 middle-aged and older adults. …”
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Evaluation of coronary perfusion pressure and diastolic blood pressure calculation methods in a swine model of pediatric cardiopulmonary resuscitation by Jeremy C. Zuckerberg, Tiffany Ko, M. Katie Weeks, Nicholas J. Widmann, Martha F. Kienzle, Hunter A. Gaudio, Luiz Eduardo V. Silva, Ron W. Reeder, Robert M. Sutton, Robert A. Berg, Todd J. Kilbaugh, Ryan W. Morgan

“…However, agreement between different calculation methods and their relative performance as outcome discriminators are not well established. …”
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Study of Physicochemical and Microbiological Quality of Fresh Camel Meat from Southern Algeria Stored at Different Temperatures Compared to Dried and Salted Camel Meat (Kadid) by Elhassan Benyagoub, Miaad K Alkhudhairy, Chahira Bessadet

“…As the most consumed source of animal protein in Southern Algeria, this study focused on monitoring the quality of fresh camel meat stored at different temperatures by analyzing some physicochemical and microbiological parameters according to national standards. …”
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A novel image segmentation method based on spatial autocorrelation identifies A-type potassium channel clusters in the thalamus by Csaba Dávid, Kristóf Giber, Katalin Kerti-Szigeti, Mihály Köllő, Zoltan Nusser, Laszlo Acsady

“…The method, originally described for geoinformatics, does not require a predefined intensity threshold or teaching algorithm for image segmentation and allows quantitative comparison of samples obtained in different conditions. …”
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Minimal Clinically Important Difference for Worsening of the University of California San Diego Shortness of Breath Questionnaire in Patients With Idiopathic Pulmonary Fibrosis Wit... by Kerri I. Aronson, MD, Ganesh Raghu, MD, Sachin Gupta, MD, Jinnie Ko, PhD, Jacob Devine, MA, Jeffrey Swigris, DO

“…Research Question: What is the MCID threshold for UCSD-SOBQ worsening in patients with IPF and less physiologic impairment? …”
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Heart Rate Variability Analysis in Congestive Heart Failure: The Need for Standardized Assessment Protocols by Monika Míková, David Pospíšil, Jan Řehoř, Marek Malik

“…Reduced HRV has consistently been found to be associated with all-cause mortality in CHF patients. However, different thresholds of long-term HRV indices have been proposed as mortality predictors; meanwhile, findings related to the prediction of other cardiac events, including sudden cardiac death, remain inconsistent. …”
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