Analysis of the circadian rhythm of intraocular pressure in stable and progressive forms of primary open-angle glaucoma by T. N. Malishevskaya, D. G. Gubin, I. V. Nemcova, A. S. Vlasova, Ju. E. Filippova, E. E. Farikova, D. S. Bogdanova

“…IOP daily dynamics was distributed differently in the different groups. In S-POAG, the peak values were mainly reached in the morning hours, while the minimum values were observed at night. …”
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The nonlinear correlation of neutrophil-lymphocyte ratio on 1-year mortality risk in patients with severe acute heart failure by Yunchao Deng, Jian Lin, Chuang Li, Rong Tian, Bo Liu

“…Kaplan-Meier survival analysis further confirmed the correctness of the threshold. The ROC was used to evaluate the diagnostic accuracy of the NLR for long-term outcomes. …”
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C1q Levels: A Reliable Biomarker for Differentiating Active and Latent Tuberculosis Infection by Sepideh Darougar, Afshin Moniri, Parvaneh Baghaei, Esmaeil Mortaz, Makan Sadr, Arad Moniri, Majid Marjani, Payam Tabarsi

“…The area under the receiver operating characteristic curve for C1q in distinguishing active from latent TB was 0.74 (95% confidence interval, 0.63–0.85), with sensitivity varying between 61% and 82% at different threshold values. Conclusions: C1q shows potential as a reliable and easily obtainable biomarker for differentiating active TB from latent infection, demonstrating high sensitivity. …”
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CN2VF-Net: A Hybrid Convolutional Neural Network and Vision Transformer Framework for Multi-Scale Fire Detection in Complex Environments by Naveed Ahmad, Mariam Akbar, Eman H. Alkhammash, Mona M. Jamjoom

“…These results outperform existing methods by 1.6% in precision, 0.3% in recall, and 3.4% in F1-score. …”
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Association of neutrophil-percentage-to-albumin ratio with mortality in older stroke survivors by Jie Huang, Xiaowei Zhang, Luyao Ding, Jiaxiang Yu, Mingshen Lin

“…RCS analysis revealed a non-linear threshold effect at NPAR = 14.5, beyond which the risk of all-cause mortality increased sharply. …”
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Clinical Characteristics and Outcomes for Neonates with Respiratory Failure Referred for Extracorporeal Membrane Oxygenator (ECMO) Support by Pooja Musuku, Keith Meyer, Felipe E. Pedroso, Fuad Alkhoury, Balagangadhar R. Totapally

“…Youden’s index was used for optimal threshold values. Chi-square, Mann–Whitney U, and binary logistic regression were used for comparative analyses. …”
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Jointly designed quasi-cyclic LDPC-coded cooperation with diversity combining at receiver by Muhammad Asif, Wuyang Zhou, Qingping Yu, Saifullah Adnan, Md Sadek Ali, Muhammad Shahid Iqbal

“…Existing methods put some limitations in terms of code length and rate in order to provide high error-correction performance. …”
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Blood-Based Prognostic Prediction Model for Glioblastoma: Construction and Validation by Gao S, Liu Y, Kong J, Huangfu L, Yang Y, Cui H, Sun X, Shi S, Yang D

“…The clinical decision curve showed that when the threshold probability exceeded 20%, the model’s prediction provided the greatest net benefit for GBM patients receiving the Stupp regimen. …”
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Belowground Biomass Carbon Density in Xinjiang Grasslands: Spatiotemporal Variability and Dominant Drivers by Ping Dong, Changqing Jing, Gongxin Wang, Yuqing Shao

“…Using extensive field sampling, multi-source remote sensing data, and machine learning methods, the spatial distribution of BGB carbon density across Xinjiang grasslands was estimated, and its environmental drivers across different geomorphological regions were revealed. …”
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Motivation for physical activity among university students residing in areas of military conflict in Ukraine by Tetiana Yermakova, Vasyl Lutskyi, Daria Piatnytska

“…Conclusions. Students living in different regions of Ukraine have varying motivations for physical activity in the context of the military conflict. …”
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A Study on Cough Sensitivity and Airway Inflammation in Patients with Sinobronchial Syndrome by Shengyuan Wang, Shanshan Niu, Siwan Wen, Mengru Zhang, Cuiqin Shi, Zhongmin Qiu, Li Yu, Xianghuai Xu

“…However, there was no difference of these threshold between SBS patients and patients with sinusitis without cough and HCs. …”
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The link between adherence to antihypertensive medications and mortality rates in patients with hypertension: a systematic review and meta-analysis of cohort studies by Xuemei Peng, Lihong Wan, Benkai Yu, Jianhui Zhang

“…This systematic review and meta-analysis specifically investigates how different levels of adherence to antihypertensive therapy (AHT) affect mortality rates in HTN patients. …”
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Association of Body Mass Index with Echocardiographic Parameters and Incidence of Left Atrial Thrombus or Spontaneous Echo Contrast in Patients with Nonvalvular Atrial Fibrillation... by Yi Qiu, Shu Jiang

“…Only a few articles have investigated the relationship between BMI and the incidence of left atrial thrombus (LAT) or spontaneous echo contrast (SEC) in cases with NVAF. Methods: This single-center retrospective study was conducted at The First People's Hospital of Changzhou. …”
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Needleless graft preparation for anterior cruciate ligament reconstruction with 4-strand semitendinosus autograft: a biomechanical in vitro study using a porcine model by Peter Melcher, Stefan Schleifenbaum, Yasmin Youssef, Philipp Rolzhäuser, Pierre Hepp, Jan Theopold

“…The aim of this study was to evaluate if a 4-strand semitendinosus autograft preparation technique is non-inferior to conventional preparation techniques with regard to maximum tensile strength threshold. Methods Fresh porcine flexor tendons were used as specimens in this study. …”
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Factors related to Hb-Var in maintenance hemodialysis patients by XIAO Xiao-fen, HUANG Hai-ming, WANG Xiao-qin

“…Objective To investigation and analysis the hemoglobin variability(Hb-Var) of maintenance hemodialysis(MHD) patients in the Hubei Provincial Hospital of Traditional Chinese Medicine and explore the factors related to Hb-Var.Methods The study enrolled 56 MHD patients in the Blood Purification Center,Hubei Provincial Hospital of Traditional Chinese Medicine between December 2013 and June 2014.Demographics and characteristics at baseline were collected.The doses of erythropoietin stimulating agents(ESAs) and intravenous doses of iron,and the number of adjusting ESAs,hemodiafiltration(HDF) and hemoperfusion(HP) were recorded during a follow-up period of 6months.The laboratory parameters including hemoglobin(Hb),calcium(Ca),phosphorus(P),immunoreactive parathyroid hormone(iPTH),serum ferritin(SF),and albumin(Alb) were determined at least three times during the follow-up period of 6 months.The Hb-Var was described by Hb coefficient of variation(Hb-CV) and fluctuation across threshold of the Hb level.The factors related to HbVar were analyzed.Results(1)There were 43 patients in the groups of Hb amplitude,accounting for76.79%;(2)Hb-CV was significantly different in gender,age,age of hemodialysis,vascular access for hemodialysis,dose of intravenous iron,and the number of adjusting ESAs(P<0.05);(3)Pearson correlation analysis revealed that Hb-CV was positively correlated with dose of the number of adjusting ESAs(r=0.757,P<0.05) and dose of intravenous iron(r= 0.757,P<0.05),but negatively with age of hemodialysis(r=-0.323,P<0.05),serum ferritin(r=-0.390,P<0.05) and albumin(r =-0.418,P<0.05),but not with age,calcium,phosphorus and immunoreactive parathyroid hormone;(4) Multiple regression analysis revealed that gender,vascular access for hemodialysis,the number of adjusting ESAs,dose of intravenous iron,and SF were independently associated with HbCV.Conclusions Hb-Var occurs commonly in maintenance hemodialysis patients,and it may be more obvious in the older.Fluctuation of Hb levels is closely associated with gender,vascular access for hemodialysis,and dose of intravenous iron.However,the relationship between Hb-Var and prognosis of CKD is still controversial,which needs more studies.…”
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Presentation of the content network of HSE systematic management components and operational plan in the Arbaeen procession by Minoo Safipour, Mojgan Zaeimdar, Manouchehr Omidvari, Razi Naserifar

“…Data were analyzed using SPSS V25, and descriptive statistics (mean, SD) were calculated. The threshold for statistical significance was set at P < 0.05. …”
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Association Between Serum Methylmalonic Acid (A Marker of Mitochondrial Dysfunction) and Serum Neurofilament Light Chains in a U.S. Population: a Cross‐Sectional Analysis From NHAN... by Jun Wei, Yang Liu, Ya Li

“…This study aimed to investigate the relationship between MMA and sNfL. Methods Data were obtained from the 2013–2014 National Health and Nutrition Examination Survey (NHANES). …”
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Higher relative fat mass was associated with a higher prevalence of gallstones in US adults by Shangfen Xie, Shanni Ma, Xiaofeng Chen, Libiao Fang, Dongen Li

“…Abstract Aims Our study aimed to investigate the association between the relative fat mass (RFM) and gallstones in adults. Methods Information obtained from the National Health and Nutrition Examination Survey (NHANES) 2017–2023 was utilized to examine the correlation between RFM and gallstones based on weighted multivariable regression analysis, smoothing curve fitting, and threshold effect analyses. …”
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Key drivers for market penetration of biosimilars in Europe by Cécile Rémuzat, Julie Dorey, Olivier Cristeau, Dan Ionescu, Guerric Radière, Mondher Toumi

“…The study objective was to conduct a quantitative analysis and identify drivers of biosimilar uptake of all available biosimilars in the European Union (EU). Methods: A three-step process was established to identify key drivers for the uptake of biosimilars in the top 10 EU member states (MS) pharmaceutical markets (Belgium, France, Germany, Greece, Hungary, Italy, Poland, Spain, Sweden, and the UK): (1) literature review to identify incentive policies in place to enhance biosimilars adoption; (2) assessment of biosimilar market dynamics based on database analysis; (3) regression model analysis on price using the following explicative variables: incentive policies; price difference between the biosimilar and the originator product; distribution channel; generic uptake and generic price cut; pharmaceutical expenditure per capita; and market competition. …”
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Comprehensive study of heart rate recovery and altered ventilatory response to exercise in patients with obstructive sleep apnea by Layla Abdelhaleem Banawan, Rasha Galal Daabis, Hend Ramadan Atia Abdehaleim, Heba Ahmed Eshmawey

“…OSA patients had a reduced maximal exercise capacity expressed as lower VO2 peak, decreased BR and VO2 at anaerobic threshold compared to control group (p < 0.001, F ¼ 22.597, 68.773, and 82.90, respectively). …”
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