Towards Meaningful Interpretation of Molecular Data: Insights Gained from HMMD Challenges in <i>Salmonella</i> Detection for Future NGS Integration in Clinical Microbiology by Hyunji Kim, Soo Hyun Seo, Jae-Seok Kim, Kwang Jun Lee, Kyoung Un Park

“…<b>Methods:</b> A retrospective review of <i>Salmonella</i>-positive cases detected via the Luminex xTAG GPP was conducted from June 2016 to November 2023. …”
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The potential utility of synovial C-reactive protein, interleukin-6, and presepsin in diagnostics of periprosthetic joint infection by Lyudmila V. Lyubimova, Svetlana I. Pavlova, Nikolay S. Nikolaev, Evgeniy A. Lyubimov, Nadezhda N. Pchelova, Vladimir Y. Emelianov

“…ROC analysis, sensitivity, specificity, accuracy, and threshold values were determined for laboratory data. …”
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Long-term prognosis of left ventricular re-remodeling after surgery of ischemic cardiomyopathy: the potential of tomographic radionuclide ventriculography by V. V. Shipulin, A. I. Mishkina, M. O. Gulya, Yu. V. Varlamova, S. L. Andreev, A. S. Pryakhin, V. M. Shipulin, K. V. Zavadovsky

“…According to the ROC-analysis, the sensitivity, specificity, and AUC were 87%, 64% and 0,727 for ΔLVPSD (threshold &gt;-1); 84%, 46% and 0,691 for coronary stenosis &gt;75% &gt;75% (threshold &gt;2); 65%, 82% and 0,674 for ΔLVEF (threshold ≤4), respectively. …”
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Predicting Suicide or Self-Harm Crises Based on Decision Tree Analysis of Life Events and Coping Style: A Population-Based Study in China by Shumeng Ma, Ping Li, Liwen Ren, Ning Jia

“…While the impact of negative life events and coping styles on suicide crises showed cross-sex consistency, sex differences were observed for self-harm crises. Among male students, only interpersonal relationships exceeded the 10% threshold in importance, whereas a wider range of events surpassed this threshold for female students. …”
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Development of a droplet digital PCR assay for the detection of BK polyomavirus by Lu Ai, Yating Zhao, Chianru Tan, Lu Bai, Gang Huang, Ruizhi Wang, Hao Huang, Xuegao Yu, Yong Guo, Peisong Chen

“…Pairwise comparison (Delong test) of the ROC curves of the two systems showed a significant difference in the area under the curve, with a difference of 0.207 and a P-value <0.01. …”
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Associations of the Neutrophil-to-Lymphocyte Ratio(NLR), Triglyceride-Glucose Index (TyG), and TyG-derived indices with vitality decline in older adults in China: a study within th... by Jiaxiu Zhao, Xueying Ji, Yixin Chen, Jiaofeng Wang, Jie Chen, Yiqin Huang, Zhijun Bao

“…Restricted cubic spline (RCS) analyses explored potential nonlinear relationships and threshold effects. Receiver Operating Characteristic (ROC) curve analysis was used to assess the discriminative capacity of different models. …”
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Factors Affecting the Elevation of Inflammatory Markers Before Primary Total Hip Arthroplasty by Byung-Chan Choi, MD, PhD, Byung-Woo Min, MD, PhD, Kyung-Jae Lee, MD, PhD

“…Although the distribution of inflammatory markers was different, only CRP level was different based on normal range. …”
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1,5-anhydroglucitol in diabetes: its role in diagnostics, screening, glycemic status assessment, and the prediction of complications by V. V. Klimontov, M. V. Dashkin

“…Chromatography and enzymatic methods are used to determine 1,5-AG in blood, urine and other biological fluids. …”
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Epidemiological and health economic implications of symptom propagation in respiratory pathogens: A mathematical modelling investigation. by Phoebe Asplin, Matt J Keeling, Rebecca Mancy, Edward M Hill

“…Although this effect could be harnessed to amplify the impact of interventions that reduce symptom severity, the mechanistic representation of symptom propagation within mathematical and health economic modelling of respiratory diseases is understudied.<h4>Methods and findings</h4>We propose a novel framework for incorporating different levels of symptom propagation into models of infectious disease transmission via a single parameter, α. …”
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Research and application of image recognition-based identification for flesh browning of loquat fruits by CHEN Yujia, DENG Chaojun, ZHANG Tingting, WANG Xiuping, CHEN Xiuping, ZHAO Jianing, MA Cuilan, JIANG Jimou

“…In the evaluation of the loquat flesh browning, the browning index and browning area of the MATLAB algorithm indicated the browning situation from different dimensions, and the combination of the two methods could maximize the characterization of the browning resistance of the loquat resources. …”
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Associations of maternal PM2.5 exposure with preterm birth and miscarriage in women undergoing in vitro fertilization: a retrospective cohort study by Miaoxin Chen, Qiaoyu Chen, Gengze Liao, Chunyan Sun, Cong Liu, Xia Meng, Wentao Li, Andong Qiu, Orhan Bukulmez, Haidong Kan, Feng Wang, Lap Ah Tse, Xiaoming Teng

“…The objective of this study was to investigate the potential associations between ambient PM2.5 exposure during different periods and negative pregnancy outcomes, such as miscarriage and preterm birth, in patients who underwent assisted reproductive technology (ART).MethodsThis retrospective cohort study examined the outcomes of 2,839 infertile women aged ≤ 45 years who underwent their first fresh or frozen-thawed embryo transfer at the Shanghai First Maternity and Infant Hospital between April 2016 and December 2019. …”
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Delayed muscle fatigue during electrical stimulation of the proximal nerve using asymmetric random high-frequency carrier pulse cluster by Rui Yuan, Yang Zheng, Henry Shin, Guanghua Xu, Shengnuo Fan, Zhanhong Du

“…In addition, the simulation results showed that the delay for different fibers to reach the threshold was increased by the aSymR mode. …”
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The transfusion of prematures early school age follow-up (TOP 5): protocol for a longitudinal cohort study by Amy L. Conrad, Sara B. DeMauro, Haresh Kirpalani, Kristina Ziolkowski, Susan R. Hintz, Betty R. Vohr, Victoria Watson, Tarah T. Colaizy, Edward F. Bell, Jane E. Brumbaugh, Carla M. Bann, Sylvia M. Tan, Jamie E. Newman, Abhik Das

“…It aims to assess longer-term cognitive and functional effects of differing transfusion thresholds in the newborn period for anemia in this large, multicenter cohort. …”
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Optimal Cutoff Value of 1-Hour Postload Glucose to Identify Insulin Resistance in Women with Polycystic Ovary Syndrome by Sungwook Chun, Sihoon Lee

“…Categorization of patients based on the 1-h PG threshold showed significant differences for all laboratory variables related to insulin sensitivity/resistance, other than fasting insulin. …”
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Implementation of the 2022 AAP guidelines for neonatal hyperbilirubinemia could reduce the need for phototherapy in Italy by Carlo Dani, Monica Fusco, Marco Andreini, Giuseppe Pepe, Simone Pratesi

“…Total serum bilirubin (TSB) at the start of phototherapy, which was decided based on the guidelines of the Italian Society of Neonatology, was compared with the TSB thresholds recommended by AAP 2022 guidelines. Results Seven hundred and thirteen (82%) infants had TSB at the start of phototherapy lower than AAP 2022 threshold (16.2 ± 3.0 vs. 17.7 ± 3.4 mg/dL; P < 0.001) with a mean difference of 1.8 (0.7–2.6) mg/dL. …”
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Rat retinal function attenuation with IOP elevation is impacted by both blood pressure and intracranial pressure by Sera N. Ganearachchi, Anna K. van Koeverden, Christine T. O. Nguyen, Zheng He, Vickie H. Y. Wong, Bang V. Bui, Da Zhao

“…IntroductionTo consider how blood pressure and intracranial pressure modify the way that retinal function responds to intraocular pressure elevation in rats.MethodsSix groups of adult Long–Evans rats (n = 7–11 eyes/group, total animals 25) were anesthetized and underwent acute pressure modification. …”
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The spectral features of EEG responses to transcranial magnetic stimulation of the primary motor cortex depend on the amplitude of the motor evoked potentials. by Matteo Fecchio, Andrea Pigorini, Angela Comanducci, Simone Sarasso, Silvia Casarotto, Isabella Premoli, Chiara-Camilla Derchi, Alice Mazza, Simone Russo, Federico Resta, Fabio Ferrarelli, Maurizio Mariotti, Ulf Ziemann, Marcello Massimini, Mario Rosanova

“…In experiment 2 we stimulated M1 at resting motor threshold in order to elicit MEPs characterized by a wide range of amplitudes. …”
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Temperature influences mood: evidence from 11 years of Baidu index data in Chinese provincial capitals by Mengjiao Yin, Mengmeng Zhu

“…It introduces an innovative approach by integrating climate data with digital behavior metrics to provide objective insights into how environmental factors may influence mental health.MethodsA dataset combining daily meteorological records and Baidu search indices from 31 provincial capital cities in China (2013–2023) was used. …”
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Unique environmental effects on physical activity participation: a twin study. by Glen E Duncan, Jack Goldberg, Carolyn Noonan, Anne Vernez Moudon, Philip Hurvitz, Dedra Buchwald

“…<h4>Methods</h4>Data were obtained from 1,389 twin pairs from the community-based University of Washington Twin Registry. …”
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Comparative Cost-Effectiveness of Two Artificial Liver Therapies in Early-Stage Hepatitis B Virus-Related Acute-on-Chronic Liver Failure: A Retrospective Cohort Study by Chen J, Luo Q, Wang L, Zheng L, Zhang Y, Liu Y, Peng L, Xu W

“…Univariate and probabilistic sensitivity analyses (Bootstrap method) were used to assess parameter uncertainty.Results: Over the 90-day follow-up period, the DPMAS+LPE group had numerically higher survival rates compared to the PE group, but this difference was not statistically significant (91.04% vs 83.07%, Logrank: P=0.094). …”
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