Prediction model of axillary lymph node status using an automated breast volume ultrasound radiomics nomogram in early breast cancer with negative axillary ultrasound by Qianqing Ma, Qianqing Ma, Junli Wang, Zhengzheng Tu, Jingwen She, Jianhui Zhu, Feng Jiang, Chaoxue Zhang

“…BackgroundConstruction and validation of an automated breast volume ultrasound (ABVS)-based nomogram for assessing axillary lymph node (ALNs) metastasis in axillary ultrasound (AUS)-negative early breast cancer.MethodsA retrospective study of 174 patients with AUS-negative early-stage breast cancer was divided into a training and test with a ratio of 7:3. …”
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Empirical assessment of functional somatic disorder (FSD): frequency, applicability, and diagnostic refinement in a population-based sample by Abigail Smakowski, Judith Rosmalen, Bernd Löwe, Christopher Burton, Anne Toussaint

“…Current symptom severity and frequency thresholds need adjustment to better identify those needing treatment. …”
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P300 event-related potentials as diagnostic biomarkers for attention deficit hyperactivity disorder in children by Chuanxue Tan, Chuanxue Tan, Huimin Zhou, Anqi Zheng, Miao Yang, Chunyang Li, Ting Yang, Tingyu Li, Jie Zhang

“…ObjectivesThis study aimed to evaluate the utility of P300 event-related potentials (ERPs) as neurophysiological biomarkers for diagnosing attention deficit hyperactivity disorder (ADHD) and to establish preliminary diagnostic thresholds for their use.MethodsA total of 106 children diagnosed with ADHD and 66 healthy controls were enrolled. …”
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Statistical inference and effect measures in abstracts of major HIV and AIDS journals, 1987–2022: A systematic review by Andreas Stang, Henning Schäfer, Ahmad Idrissi-Yaghir, Christoph M. Friedrich, Matthew P. Fox

“…The aim of this study was to describe time trends of statistical inference and effect measure reporting of major HIV/AIDS journals Methods: We included 10 major HIV/AIDS journals and analyzed all available PubMed entries for the period 1987 through 2022. …”
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Effects of Apnea-Induced Hypoxia on Hypoalgesia in Healthy Subjects by Cristian Mendoza-Arranz, Omar López-Rebenaque, Carlos Donato Cabrera-López, Alejandro López-Mejías, José Fierro-Marrero, Francisco DeAsís-Fernández

“…Hypoalgesia was tested with pressure pain thresholds (PPTs) and CPM. Oxygen saturation (SpO₂) and HR were also tested. …”
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Cost-Effectiveness of Introducing Nuvaxovid to COVID-19 Vaccination in the United Kingdom: A Dynamic Transmission Model by Clive Pritchard, Lucie Kutikova, Richard Pitman, Kira Zhi Hua Lai, Hadi Beyhaghi, IIana Gibbons, Amanda Erbe, Marija Živković-Gojović, Catherine Cosgrove, Mark Sculpher, David Salisbury

“…Cost savings were driven by reduced cold chain-related operational costs and vaccine wastage, while QALY gains were driven by potential differences in vaccine tolerability. Probabilistic sensitivity analysis indicated an approximately 70% probability of cost-effectiveness with Nuvaxovid-only versus mRNA-only vaccination across most cost-effectiveness thresholds (up to GBP 300,000/QALY gained). …”
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A Comparative Study of Liver and Kidney Function Indicators in Patients with Beta-thalassemia Major and Beta-thalassemia Trait by Enaam AL-Dagestani, Mohammad Hamza, Nabaa Yusif

“…Further research is needed to clarify ferritin thresholds for toxicity versus protection.…”
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Nocturnal urine 6-hydroxy sulfate melatonin is associated with the outcome of subjects with sepsis by Wenjie Li, Jiameng Chen, Shuming Pan, Chengjin Gao

“…This study investigated the relationship between melatonin secretion and outcome of sepsis after 28-day admission. Methods. Patients with sepsis were randomly divided into an eye mask group and a control group. …”
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Validity and reliability of healthy food knowledge and healthy food preferences scale for preschool children by Aklilu Abrham Roba, Aklilu Abrham Roba, Öznur Başdaş

“…CFA confirmed the model fit, with all indices meeting the recommended thresholds. The HFK_PS and HFP_PS scales demonstrated good internal consistency, with Cronbach's alpha values of 0.80 and 0.78, respectively. …”
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Rates of achieving meaningful outcomes after undergoing minimally-invasive far lateral tubular decompression by Ameen Barghi, Anirudh Gowd, Edward Beck, Marcel Brown, Evan M. Miller, Ziyad Knio, Matthew Jamison, Tadhg O’gara

“…The study calculated thresholds for achieving minimal clinically important difference (MCID) on each PRO and performed logistic regression analysis to identify predictors of achieving meaningful clinical outcomes and clinical failure. …”
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Differential diagnosis of aortic aneurysms: pathomorphological criteria of various etiological forms by Bokhodir A. Magrupov, Abdusalom A. Abdurakhmanov, Khamidulla A. Abdumajidov, Odilbek S. Sultanov

“…Objective: To identify morphological features of aortic wall structure in various pathologies that could serve as differential diagnostic criteria. Methods: The study was conducted at the Pathology Department of the Republican Research Center for Emergency Medicine (Tashkent, Uzbekistan) from January 2024 to May 2025. …”
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A TARGET database-driven nomogram for pediatric osteosarcoma prognosis by Jianfeng Li, Jiayi Li, Jianjun Wang, Bingquan Li

“…Decision curve analysis indicated that the model has substantial net benefit across a wide range of mortality risk thresholds. Kaplan-Meier survival analysis showed significant differences in prognosis between high-risk and low-risk groups. …”
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Evaluation of diastole by echocardiography for detecting early cardiac dysfunction: an outcome study by Tatiana Kuznetsova, Nicholas Cauwenberghs, František Sabovčik, Yukari Kobayashi, Francois Haddad

“…Conclusions Our study underscored the importance of considering age‐ and population‐derived thresholds in LVDDF grading in subjects at high cardiovascular risk which led to a better risk stratification and outcome prediction.…”
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Improving patient understanding of GEP test results (IMPARTER4): an RCT by Valerie Jenkins, Lesley Fallowfield, Lucy Matthews, Ivonne Solis-Trapala, Rachel Starkings, Shirley May

“…The total knowledge score was higher in Group B (estimated between groups mean difference of 2.5 (95% CI:1.7 to 3.4) p<0.001). Most treatment decisions adhered to recommended risk of recurrence thresholds, although patients with higher trait anxiety were more likely to make less apparently rational decisions OR=0.93 (95%CI 0.88 to 0.97) p=0.002 (163/230; 70.8% received ET alone; 65/230; 28% ET plus chemotherapy, and two sought second opinions). …”
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Recommendations on phenylketonuria in Turkey by Turgay Coşkun, Mahmut Çoker, Neslihan Önenli Mungan, Hülya Gökmen Özel, H Serap Sivri

“…PKU follow-up is a dynamic process with uncertainties and differences in clinical practice. …”
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Validation and adaptation of the Arabic version of health-related quality of life with six domains (HRQ-6D): A factor and Rasch analyses study. by Walid Al-Qerem, Anan Jarab, Abdel Qader Al Bawab, Judith Eberhardt, Fawaz Alasmari, Alaa Hammad, Lujain Al-Sa'di, Raghd Obidat, Sarah Abu Hour, Taha Al-Hayali

“…Additionally, all items of the Ar-HRQ-6D fell within the acceptable infit and outfit ranges. All thresholds were appropriately ordered, ranging from -5.27 to 2.86. …”
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Combined evaluation of geriatric nutritional risk index and modified creatinine index for predicting functional dependence in patients on Hemodialysis by Rong Ni, Peng Qian, Ci Sun, Yusheng Xu, Kai Song, Weiwei Li

“…Logistic regression highlighted significant differences in the risk of functional dependence among the four groups based on GNRI and mCI thresholds (P < 0.05). …”
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Comparing Out-of-Pocket Costs and Health-Related Quality of Life Between Sodium-Glucose Cotransporter 2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists in Patients with Ty... by Hu S, Zanwar PP, Jenkins T, Sevak RJ, Jasti BR

“…No significant difference existed between the two treatments for total prescription expenditures (median: &dollar;9831.53vs. …”
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Dynamic Anterior Shoulder Stabilization Using a Long Head of the Biceps Transfer and Bankart Repair Improves Clinical Outcomes in Patients With Subcritical Bone Loss: A Systematic... by Neil Jain, M.D., Jonathan McKeeman, M.D., M.B.A., Margaret Higgins, M.D., Alexander Johnson, M.D., Tyler Smith, D.O., Brian Waterman, M.D.

“…Rowe scores showed improvements ranging from 54.5 to 74.0 points, with 87.9% to 100% of patients meeting minimal clinically important difference thresholds. Changes in forward flexion and external rotation ranged from 3° to 23° and –2.3° to 8.3°, respectively. …”
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Neurofilament Light Chain in Cerebrospinal Fluid and Blood in Multiple System Atrophy: A Systematic Review and Meta-Analysis by Silvia Demiri, Dimitra Veltsista, Vasileios Siokas, Kanellos C. Spiliopoulos, Antonia Tsika, Polyxeni Stamati, Elisabeth Chroni, Efthimios Dardiotis, Ioannis Liampas

“…Standardized mean differences (SMDs) were calculated separately for CSF and blood NfL per comparison. …”
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