Eradication of Helicobacter pylori for prevention of aspirin-associated peptic ulcer bleeding in adults over 65 years: the HEAT RCT by CJ Hawkey, Anthony J Avery, Carol AC Coupland, Colin J Crooks, Jennifer S Dumbleton, FD Richard Hobbs, Denise Kendrick, Michael Moore, Clive Morris, Gregory Rubin, Murray Smith, Diane Stevenson

“…We investigated whether H. pylori eradication would protect against aspirin-associated ulcer bleeding. Methods The Helicobacter Eradication Aspirin Trial was a randomised placebo-controlled trial (European Union Drug Regulating Authorities Clinical Trials 2011-003425-96), conducted in United Kingdom primary care using routinely collected clinical data. …”
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Climate Change and Outdoor Workers: A Narrative Review by Mehdi Asghari, Mohammad Javad Ghanadzadeh, Razieh Soltani Gerdfaramarzi

“…Adapting to climate change: Thresholds, values, governance. 2009:181-96. Tirgar A, Shirouye A, Hajiahmadi M, Hoseini S. …”
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Impact of Language Barriers and Age on English Hearing Test App Accuracy for Polish Users by Małgorzata Pastucha, Elżbieta Gos, Henryk Skarżyński, W. Wiktor Jedrzejczak

“…They were divided into 3 groups based on their proficiency in English: no knowledge (Group 1), basic (Group 2), and advanced (Group 3). The mean differences between hearing thresholds determined using the app and the reference tests were measured for each group. …”
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Quantitative somatosensory assessments in patients with persistent pain following groin hernia repair: A systematic review with a meta-analytical approach. by Akhmedkhan Dubayev, Elisabeth Kjær Jensen, Kenneth Geving Andersen, Martin F Bjurström, Mads U Werner

“…Compared with the contralateral side or controls, there were significant alterations in somatosensory function of the surgical site in PPSP-patients. Following thresholds were significantly increased: mechanical detection thresholds for punctate stimuli (mean difference (95% CI) 3.3 (1.6, 6.9) mN (P = 0.002)), warmth detection thresholds (3.2 (1.6, 4.7) °C (P = 0.0001)), cool detection thresholds (-3.2 (-4.9, -1.6) °C (P = 0.0001)), and heat pain thresholds (1.9 (1.1, 2.7) °C (P = 0.00001)). …”
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Cervical ripening at home or in hospital during induction of labour: the CHOICE prospective cohort study, process evaluation and economic analysis by Mairead Black, Cassandra Yuill, Mairi Harkness, Sayem Ahmed, Linda Williams, Kathleen A Boyd, Maggie Reid, Amar Bhide, Neelam Heera, Jane Huddleston, Neena Modi, John Norrie, Dharmintra Pasupathy, Julia Sanders, Gordon C S Smith, Rosemary Townsend, Helen Cheyne, Christine McCourt, Sarah Stock

“…Impact of COVID-19 Of responding sites, 23% reported a change in the method used for cervical ripening and 28% reported a change in criteria for offering home cervical ripening. …”
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Effects of Acitretin Treatment on Hearing in Patients with Psoriasis Vulgaris by Başak Mutlu, Merve Torun Topçu, Ayşe Serap Karadağ, Yasemin Gündüz, Mahmut Tayyar Kalcıoğlu

“…Results: During the acitretin treatment for the PV group, the hearing thresholds of 4,000 Hz (right ear, p=0.004) presented a significant difference that did not have a worsening effect. …”
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Is Gentamicin-Induced Ototoxicity Reversible with Delayed Administration of Nigella Sativa Oil? An Experimental Study by Bilge Tuna, Gökhan Tüzemen

“…However, a significant increase in ABR thresholds was observed only in Group 3. A significant difference was found in post-treatment hearing thresholds (p<0.001) between Group 3 and the other two groups. …”
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Visualization of Critical Limits and Critical Values Facilitates Interpretation by Ania Shah, Jenna Dohner, Kaifeng Cheng, Maria Garcia, Gerald J. Kost

“…<b>Background/Objectives:</b> This study aimed to analyze critical limit and critical value test lists from major US medical centers, identify changes in quantitative critical limit thresholds since 1990, document notification priorities for qualitative and new listings, and visualize information alongside clinical thresholds and pathophysiological trends. …”
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Patient Outcomes of Thumb Arthroplasty Using a Hybrid Technique for Severe Osteoarthritis by Shiny Chih-Hsuan Wu, MD, Chen-Heng Hsu, MD, Chieh-An Chuang, MD, Sheu Huan, MD, You-Hung Cheng, MD, Cheng-Pang Yang, MD, Joe Chih-Hao Chiu, MD, PhD, Chun-Ying Cheng, MD, Yi-Shen Chan, MD, Alvin Chao-Yu Chen, MD

“…Receiver operating characteristic curves derived clinically significant outcome (CSO) thresholds of minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient acceptable symptom state (PASS). …”
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Comparative analysis of sensory-motor function and its correlation with gait biomechanics in patients with unilateral chronic ankle instability by QiLong Gao, Jiao Li, Qi Wang, Dan Liu, Lei Guo

“…Postural stability was quantified by jump-landing test for stabilization time in the anterior-posterior direction; proprioception was quantified by bilateral thresholds for ankle plantarflexion, dorsiflexion, inversion, and eversion; and plantar sensation was determined by measuring the minimum thresholds of sensation in the five plantar regions. …”
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Proprioceptive Control of Muscle Activation in Aging: Implications for Balance and Fall Risk by Łukasz Oleksy, Anna Mika, Martyna Sopa, Artur Stolarczyk, Olga Adamska, Joanna Zyznawska, Rafał Buryta, Paulina Ciepiela, Jarosław Witkowski, Renata Kielnar

“…In each of the three thresholds, it did not exceed 10% MVC and significantly differed only between the 15% and 60% MVC thresholds. …”
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Comparison of dose calculation approaches and clinical dose–response in image-guided head&neck brachytherapy of the oral cavity by Sabrina Schaller, Vratislav Strnad, Claudia Schweizer, Dorota Lubgan, Ricarda Merten, Rainer Fietkau, Christoph Bert, Andre Karius

“…Target volumes ≥ 10.2–11.8ccm were associated with increased rates of soft tissue necrosis and mucositis. Dosimetric thresholds and correlations differed between TG-43 and MBDCA. …”
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Efficacy of a Low-Cost Weight-Bearing Sensitivity Incentivator After Lower Limb Surgery: A Pilot Randomised Controlled Trial by Alessandro Manelli, Isella Carola, Fabrizio Mancini, Schiavone Nicola, Rathlef Daniel, Marina Protasoni, Andrea Brambilla, Piero Antonio Zecca

“…Background: Accurate partial weight-bearing (PWB) is essential for postoperative recovery after lower limb surgery, yet patients often fail to maintain load within clinically meaningful thresholds. Methods: In this pilot randomised controlled trial with 1:1 concealed allocation, 34 inpatients aged 18–85 who underwent femoral fracture fixation, hip arthroplasty, or knee arthroplasty were enrolled and followed for 14 days. …”
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Evaluating the Effect of High‐Translucent Zirconia Thickness and Substrate Shade on the Final Color of the Restoration by Mahnaz Hatami, Elham Jalali, Mohamad Hossein Lotfi Kamran, Alireza Danesh Kazemi, Amirhossein Fathi

“…They were placed on composite substrates with A2, A3.5, and C3 colors (n = 10). The color differences (ΔE) of the ceramic disks on the A3.5 and C3 substrate compared to the control group (A2) were calculated and compared with acceptable thresholds (ΔE = 5.5) and perceptible thresholds (ΔE = 2/6). …”
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Worldwide practices in pulmonary function test reporting after lung transplantation by Jens Gottlieb, MD, Erika Lease, MD, Merel Hellemons, MD, PhD, Kieran Halloran, MD, Tereza Martinu, MD, MHSc

“…Methods: In April 2025, a 10-question online survey was conducted among International Society of Heart and Lung Transplantation-members to determine the reference values and normal thresholds used worldwide for post-transplant spirometry interpretation. …”
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Digital hand‐held arthrometry is a reliable and accurate adjunct for diagnosing acute anterior cruciate ligament tears by Richard Norris, Alan Price, Thomas W. Maddox, William Boswell, Cronan Kerin, Rachel A. Oldershaw

“…Abstract Purpose To evaluate the intrarater reliability and predictive validity of Lachmeter® measurements for diagnosing acute anterior cruciate ligament (ACL) tears, and to propose diagnostic thresholds. Methods Lachmeter® measurements were recorded during the stabilised Lachman test for consecutive participants presenting to an acute knee injury clinic within 21‐days of injury. …”
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Industrial noise: impacts on workers’ health and performance below permissible limits by Özge Gedik Toker, Nida Tas Elibol, Elif Kuru, Zeynep Görmezoğlu, Ali Görener, Kerem Toker

“…Participants' air conduction hearing thresholds (0.5–8 kHz) were measured using an Interacoustics AS608 audiometer. …”
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Scaling of vagus nerve stimulation parameters does not achieve equivalent nerve responses across species by Eric D. Musselman, Ishani Raha, Nicole A. Pelot, Warren M. Grill

“…We defined “K” as the ratio of activation thresholds between a pair of individuals. We used a mixed model ANOVA on the natural logarithm of K to test for differences in inter-species Ks across fiber types and pulse widths. …”
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Evaluation of the Vestibulocochlear System in Patients with Pseudoexfoliation Syndrome by Mustafa Değer Bilgeç, Nagehan Erdoğmuş Küçükcan, Leman Birdane, Armağan İncesulu, Nilgün Yıldırım

“…A statistically significant difference was found between the study group and the control group (p<0.05).Conclusion:Patients with PES showed elevation in pure-tone thresholds and a decrease in superior and inferior vestibular nerve function, demonstrating that the vestibular system as well as the auditory system are affected in PES.…”
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The clinical analysis and indications for exchange transfusion in 158 children with pertussis characterized by marked leukocytosis by Gaihuan Zheng, Qing Liu, Chuan Gan

“…Abstract Background Hyperleukocytosis (WBC ≥ 30 × 10⁹/L) strongly associated with fatal outcomes; evidence-based thresholds for initiating exchange transfusion (ET) remain undefined. …”
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