Post-craniotomy intracranial pressure monitoring: a novel approach combining optic nerve sheath diameter ultrasonography and cervical-cerebral arterial ultrasound by Zunfeng Fu, Lin Peng, Laicai Guo, Naixia Hu, Yamin Zhu, Shouxin Tang, Hongliang Lou, Jiajun Zhang, Chongqiang Wang

“…Finally, receiver operator characteristic curves (ROC) were also analyzed for different indexes and their combinations (using logistic model).ResultsSignificant differences were observed between the normal and elevated ICP groups with respect to ONSD, PI-ratio, MCAPI and MCAFVd (diastolic flow velocity of MCA) (p < 0.05). …”
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Influence of temperature and humidity on contrail formation regions in the general circulation model EMAC: a spring case study by P. Peter, P. Peter, S. Matthes, C. Frömming, P. Jöckel, L. Bugliaro, A. Giez, M. Krämer, M. Krämer, V. Grewe, V. Grewe

“…Sensitivity experiments with varying thresholds of relative humidity over ice illustrate trade-offs between achieving high hit rates and minimising false alarms in contrail detection. …”
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Olympic combat sports and mental health in children and adolescents with disability: a systematic review of controlled trials by Youngjun Lee, Flavia Guidotti, Flavia Guidotti, Laura Capranica, Caterina Pesce, Valentin Benzing, Janet Hauck, Simone Ciaccioni, Simone Ciaccioni

“…Family involvement and age emerged as potential moderators, with older children and adolescents with engaged carers likely to benefit even more.DiscussionsDespite different study protocols, outcomes, and risk-of-bias thresholds, OCS interventions overwhelmingly seem to enhance mental health in children and adolescents with disabilities. …”
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Screening for Depression and Anxiety Using a Nonverbal Working Memory Task in a Sample of Older Brazilians: Observational Study of Preliminary Artificial Intelligence Model Transfe... by Alexandra Livia Georgescu, Nicholas Cummins, Emilia Molimpakis, Eduardo Giacomazzi, Joana Rodrigues Marczyk, Stefano Goria

“…We seek to validate the models’ performance by applying it to a new dataset comprising older Brazilian adults, thereby exploring its transferability and generalizability across different demographics and cultures. MethodsA total of 69 Brazilian participants aged 51-92 years old were recruited with the help of Laços Saúde, a company specializing in nurse-led, holistic home care. …”
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A Non-Surgical Wearable Option for Bone Conduction Hearing Implants: A Comparative Study with Conventional Bone Conduction Hearing Aids Mounted on Eyeglasses by Federica Di Berardino, Giovanni Ciavarro, Giulia Fumagalli, Claudia Albanese, Enrico Pasanisi, Diego Zanetti, Vincenzo Vincenti

“…Unaided and aided pure-tone air conduction (AC) and bone conduction (BC) thresholds, as well as speech tests in quiet and noise, were recorded at baseline and in two different settings: with a BCHI mounted on SoundArc^® and with their own BCHAs mounted on eyeglasses using two couplers. …”
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Cost-effectiveness of Evolocumab in Cardiovascular Disease: A Systematic Review by Nashmil Ghadimi, Rajabali Daroudi, Hosein Shabaninejad, Mahshad Goharimehr, Davoud Khodamorzideh, Sara Kaveh

“…Sensitivity analyses revealed factors influencing cost-effectiveness outcomes, including Low-Density Lipoprotein Cholesterol (LDL-C) levels, Evolocumab costs, and disease type, while several studies reported accepted thresholds for cost-effectiveness analysis. Conclusions: Our systematic review concludes that Evolocumab could be a cost-effective treatment, particularly for high-risk patient groups, but this varies by disease category, risk level, and evaluation methods. …”
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Finite element analysis of short-segment fixation combined with expandable polyetheretherketone vertebral body replacement in osteoporotic vertebrae by Long Chen, Xiaozhen Wang, Markus Kröber, Elhassan Abdelmonem, Xuan Wan

“…Four fixation models were developed using SolidWorks based on different posterior fixation methods and VBR materials. …”
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Cost-effectiveness analysis of proactive home visits compared with site-based community health worker care on antenatal care outcomes in Mali: a cluster-randomised trial by Osondu Ogbuoji, Caroline Whidden, Emily Treleaven, Youssouf Keita, Kassoum Kayentao, Ari Johnson, Jenny X Liu, Minahil Shahid, Mohamed Berthé, Armand Zimmerman, David Charles Boettiger, Coumba Traoré, Mahamadou Sogoba, Saibou Doumbia, Amadou Beydi Cissé

“…We estimated programme costs, incremental cost-effectiveness ratios (ICERs) and probabilities of the intervention being more cost-effective than the control at different willingness-to-pay (WTP) thresholds.Results Proactive home visits were cost-saving from the CHW programme’s perspective (ICERs: −$21.39 to −$79.20 per ANC utilisation outcome) and from the Full ANC programme perspective (ICERs: −$1.70 to −$6.30 per ANC utilisation outcome) compared with the fixed-site CHW care. …”
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Preclinical gout is common in the patient with stage 3–5 chronic kidney disease. Relevance of musculoskeletal ultrasound by Enrique Calvo-Aranda, Laura Barrio Nogal, Boris Anthony Blanco Caceres, Diana Peiteado, Marta Novella-Navarro, Eugenio De Miguel, Jaime Arroyo Palomo, Roberto Alcázar Arroyo, Juan Antonio Martín Navarro, Milagros Fernandez Lucas, Martha Elizabeth Diaz Dominguez, Marco Antonio Vaca Gallardo, Elda Besada Estevez, Leticia Lojo Oliveira

“…Objectives: To assess the prevalence of urate deposit in stages 3–5 CKD detected by US, and to investigate if there are differences between AH and NU patients. Methods: Multicenter cross-sectional study, recruiting patients aged ≥18 years with AH and stages 3–5 CKD in 4 hospitals. …”
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Identification of Novel Gene-Specific Markers for Differentiating Various Pathogenic <i>Campylobacter</i> Species Using a Pangenome Analysis Approach by Emmanuel Kuufire, Kingsley E. Bentum, Rejoice Nyarku, Viona Osei, Asmaa Elrefaey, Tyric James, Yilkal Woube, Raphael Folitse, Temesgen Samuel, Woubit Abebe

“…The results revealed substantial genomic diversity within the genus, with core gene counts varying across different nucleotide identity thresholds. Ribosomal genes such as <i>rpsL</i>, <i>rpsJ</i>, <i>rpsS</i>, <i>rpmA</i>, <i>rpsK</i>, <i>rpsU</i>, <i>rpsG</i>, <i>rpmH</i>, and <i>rpsZ</i> were consistently identified in the core genome, whereas accessory genes exhibited marked variability. …”
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Association of urinary metal elements with sarcopenia and glucose metabolism abnormalities: Insights from NHANES data using machine learning approaches by Xinmin Jin, Lei Li, Xiaoyan Hu, Pengfei Bi, Song Zhang, Qian Wang, Zhongwei Xiao, Hua Yang, Tongtong Liu, Lifang Feng, Jinhuan Wang

“…Methods: Data from the 2011–2014 National Health and Nutrition Examination Survey (NHANES) were used, involving 2390 participants with complete data on urinary metal elements, diabetes, and sarcopenia. …”
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Development of an artificial intelligence-based application for the diagnosis of sarcopenia: a retrospective cohort study using the health examination dataset by Chang-Won Jeong, Dong-Wook Lim, Si-Hyeong Noh, Sung Hyun Lee, Chul Park

“…The T-Score-based analysis provided reliable diagnostic thresholds for sarcopenia, facilitating consistent and accurate assessments. …”
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Four-Year Analysis of a Five-Year Prospective Multicenter Study Assessing Radiographic Recurrence and Patient Outcomes Following Triplanar Tarsometatarsal Arthrodesis with Early We... by Daniel C. Farber MD, Dane K. Wukich MD, Robert D. Santrock MD, Abdi Raissi MD, Avneesh Chhabra MD, Jennifer Koay MD, Paul Dayton DPM, Jody P. McAleer DPM, Robert Taylor DPM, Dan Hatch DPM, Deidre Kile BS

“…The primary endpoint of this study is radiographic recurrence of HV, with recurrence reported at two different thresholds commonly utilized in the literature: post-operative HVA > 15° and HVA > 20°. …”
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Association between tinnitus and hearing impairment among older adults with age-related hearing loss: a multi-center cross-sectional study by Zhifeng Chen, Zhifeng Chen, Zhifeng Chen, Yan Lu, Yan Lu, Chenyu Chen, Chenyu Chen, Shaolian Lin, Shaolian Lin, Ting Xie, Xiaoyang Luo, Xiaoyang Luo, Yanchun Lin, Yanchun Lin, Yuqing Chen, Yuqing Chen, Yong Feng, Guanxia Xiong, Xiulan Ma, Chaojun Zeng, Chaojun Zeng, Chaojun Zeng, Chang Lin, Chang Lin, Chang Lin

“…This study aimed to reveal the association between tinnitus and hearing impairment among older adults with age-related hearing loss (ARHL).MethodsThis cross-sectional study was conducted among a population of outpatients diagnosed with ARHL at four medical centers in different regions of China, from June 2020 to June 2023. …”
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The burden of rare cancers among adults in the Canton of Geneva, Switzerland, from 2011 to 2020 by Nathalie Bot, Evelyne Fournier, Marie-Laure Amram, Laura Botta, Alice Bernasconi, Elisabetta Rapiti

“…Five-year survival rates were estimated using the Kaplan–Meier method. Survival differences between rare and common cancers were assessed using log-rank tests and Cox proportional hazards models adjusted for age and gender. …”
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Left bundle branch area pacing in patients with severe interventricular septal hypertrophy: A multicenter study assessing feasibility, safety, and outcomes of lumenless and stylet-... by Sanjai Pattu Valappil, MD, DM, Abhinav B. Anand, MD, DM, Anindya Ghosh, MD, DM, Krishnaswamy Subramanyan, MD, DM, Pramod Jaiswal, MD, DM, Krishnan Jayanthi, MD, DNB, Golla N. Prasad, MD, DNB, Tirupattur S. Srinath, MD, DNB, Shilpa Menon, MD, DM, Sharan Shreedhar, MD, Karthikeyan D, DMRD, DNB, Radiology, Velayudhan Bashi, MS, MCH, Justin Paul, MD, DNB, DM, Elangovan Elavarasi Manimegalai, MD, DM, Immanuel Sathiakumar Arunkumar, MD (General Medicine), DM (Cardiology), Sriram Veeraraghavan, MD, DM, Saran G. Kumar, BSc, Soli Rajaram Ramkumar, MD, DM, Raniya Palliyedath, MBBS, Shaima Hafeez, MBBS, Ulhas M. Pandurangi, MD, DM

“…Objective: This study assesses the feasibility, safety, and outcome of LBBAP in patients with severe IVSH. Methods: 19 adult patients with severe IVSH who underwent LBBAP were enrolled. …”
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Integrative radiomics of intra- and peri-tumoral features for enhanced risk prediction in thymic tumors: a multimodal analysis of tumor microenvironment contributions by Liang zhu, Jiamin Li, Xuefeng Wang, Yan He, Siyuan Li, Shuyan He, Biao Deng

“…To further evaluate the effectiveness of these models, various statistical methods were applied, including DeLong’s test, NRI, and IDI, to compare predictive differences among models. …”
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Validating the pathogenic mechanism of chronic obstructive pulmonary disease induced by negative emotions via Mendelian randomization and traditional Chinese medicine theory of emo... by Zhiying Wang, Yun Li, Zhixian Zhong, Ling Xu, Yi Zhong, Jian Chen

“…Weak instrument bias was mitigated via F-statistic thresholds (> 10). All analyses were conducted in RStudio. …”
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Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1 by Andres Rosende, Cesar Romero, Donald J. DiPette, Jeffrey Brettler, Patrick Van der Stuyft, Gautam Satheesh, Pablo Perel, Niamh Chapman, Andrew E. Moran, Aletta E. Schutte, James E. Sharman, Vilma Irazola, Mark D. Huffman, Norm R. C. Campbell, Abdul Salam, Fernando Lanas, Antonio Coca, Sebastian Garcia-Zamora, Alejandro Ferreiro, Patricio Lopez-Jaramillo, Jorge Rico-Fontalvo, Emily Ridley, Dean Picone, David Flood, Daniel José Piñeiro, Carolina Neira Ojeda, Gonzalo Rodriguez, Irmgardt A. Wellmann, Marcelo Orias, Marcela Rivera, Matías Villatoro Reyes, Oyere Onuma, Shaun Ramroop, Taskeen Khan, Yamile Valdes Gonzalez, Weimar Kunz Sebba Barroso, Frida L. Plavnik, Eric Zuniga, Ana María Grassani, Carlos Tajer, Ezequiel Zaidel, Marcos J. Marin, Shana Cyr-Philbert, Ignacio Amorin, Miguel Angel Diaz Aguilera, Luiz Bortolotto, Alvaro Avezum, Antonio Luiz P. Ribeiro, Sheldon Tobe, Teresa Aumala, Sonia Angell, Pablo Lavados, Sheila Ouriques Martins, Ana Munera Echeverri, Marc G. Jaffe, Dorairaj Prabhakaran, Gianfranco Parati, Xin Hua Zhang, Anthony Rodgers, Salim Yusuf, Paul K. Whelton, Pedro Ordunez

“…Second, international experts from different disciplines proposed interventions to enhance the HEARTS Clinical Pathway. …”
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Association of non-optimum temperature, heatwaves and cold spells with chronic obstructive pulmonary disease mortality: A nationwide time-stratified case-crossover study by Kexin Yu, Shuo Jiang, Su Shi, Xia Meng, Renjie Chen, Haidong Kan, Peng Yin, Maigeng Zhou, Feng Tan, Cong Liu, Xunliang Tong

“…The findings on vulnerable populations and differential risks in different regions may contribute to the targeted prevention and alarming system.…”
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