The association of visceral and subcutaneous fat areas with phenotypic age in non-elderly adults, mediated by HOMA-IR and HDL-C by Yuanhong Liu, Min Xu, Liqing Wang, Linyun Meng, Mengran Li, Shumin Mu

“…Conclusion In this study, the nonlinear relationships among abdominal SFA, VFA, and PhenoAgeAccel were elucidated, while characteristic thresholds across different age groups were identified. …”
Get full text

QUANTITATIVE ANALYSIS OF LIVER IRON DEPOSITION BASED ON DUAL-ENERGY CT IN THALASSEMIA PATIENTS by Fengming Xu, Cheng Tang, Yiling Huang, Linlin Liang, Fuling Huang, Gaohui Yang, Peng Peng

“… Objective: To explore the feasibility and accuracy of liver iron deposition based on dual-energy CT in thalassemia patients. Materials and methods: 105 thalassemia patients were examined with dual-energy CT and MR liver scanning. …”
Get full text

Optimized Production of Virus-like Particles in a High-CHO-Cell-Density Transient Gene Expression System for Foot-and-Mouth Disease Vaccine Development by Ana Clara Mignaqui, Alejandra Ferella, Cintia Sánchez, Matthew Stuible, Romina Scian, Jorge Filippi, Sabrina Beatriz Cardillo, Yves Durocher, Andrés Wigdorovitz

“…Titers remained above protective thresholds up to 60 dpv with a single dose. A booster at 28 dpv further elevated titers to levels comparable to those induced by the inactivated vaccine. …”
Get full text

Variability in performance of genetic-enhanced DXA-BMD prediction models across diverse ethnic and geographic populations: A risk prediction study. by Yong Liu, Xiang-He Meng, Chong Wu, Kuan-Jui Su, Anqi Liu, Qing Tian, Lan-Juan Zhao, Chuan Qiu, Zhe Luo, Martha I Gonzalez-Ramirez, Hui Shen, Hong-Mei Xiao, Hong-Wen Deng

“…This study aims to develop BMD prediction models using data from the UK Biobank (UKBB) and test their performance across different ethnic and geographical populations.<h4>Methods and findings</h4>We developed BMD prediction models for the femoral neck (FNK) and lumbar spine (SPN) using both genetic variants and clinical factors (such as sex, age, height, and weight), within 17,964 British white individuals from UKBB. …”
Get full text

Ergotamine enhances circadian amplitude and diurnally mitigates nitroglycerin-induced mechanical hypersensitivity by Chorong Han, Hwayoung Baek, Ji Ye Lim, Eunju Kim, Celia K. Tran, Emma Freeman, Zheng Chen, Seung-Hee Yoo, Mark J. Burish

“…Ergotamine’s peak effect on hindpaw thresholds at ZT4 suggests that ergotamine may be more effective at certain times of day.…”
Get full text

Supporting self-management with an internet intervention for low back pain in primary care: a RCT (SupportBack 2) by Adam W A Geraghty, Taeko Becque, Lisa C Roberts, Jonathan Hill, Nadine E Foster, Lucy Yardley, Beth Stuart, David A Turner, Gareth Griffiths, Frances Webley, Lorraine Durcan, Alannah Morgan, Stephanie Hughes, Sarah Bathers, Stephanie Butler-Walley, Simon Wathall, Gemma Mansell, Malcolm White, Firoza Davies, Paul Little

“…Methods The study design was a three parallel-arm, multicentre randomised controlled trial with a nested mixed-methods process evaluation. …”
Get full text

Cost-effectiveness of tenofovir disoproxil fumarate prophylaxis for perinatal hepatitis B virus prevention in Ethiopia: a decision analytical modeling by Abdi Gari Negasa, Firew Tekle Bobo, Desalegn Feleke Falta, Temesgen Kabeta Chala, Negalign Berhanu Bayou

“…We aimed to identify a cost-effective strategy for using TDF to prevent perinatal HBV transmission in Ethiopia. Methods A decision tree combined with a Markov model was used to determine the cost-effectiveness of different strategies for preventing perinatal transmission of HBV in a cohort of 10,000 hepatitis B surface antigen (HBsAg)-positive pregnant women. …”
Get full text

Interim Analysis of a Prospective Multicenter Study Assessing Radiographic and Patient Outcomes Following a Mini-Open Triplanar Tarsometatarsal Arthrodesis with Early Weightbearing by Justin L. Daigre MD, Robert D. Santrock MD, Avneesh Chhabra MD, Jeffrey McAlister DPM, Robert Taylor DPM, Daniel C. Farber MD, Abdi Raissi MD, Paul Steinke DPM, Marque Allen DPM, Amber Shane DPM, Deidre Kile BS, Jody P. McAleer DPM

“…The primary endpoint of this study is radiographic recurrence of HV, with recurrence reported using two different thresholds commonly utilized in the literature: post-operative HVA >15° and HVA >20°. …”
Get full text

Deep Learning-Based Differentiation of Vertebral Body Lesions on Magnetic Resonance Imaging by Hüseyin Er, Murat Tören, Berkutay Asan, Esat Kaba, Mehmet Beyazal

“…In this study, we aim to detect and classify vertebral body lesions using the YOLO-v8 (You Only Look Once, version 8) deep learning architecture. <b>Materials and Methods:</b> This study included MRI data from 235 patients with vertebral body lesions. …”
Get full text

Effectiveness of ballistic exercises for increasing upper body explosive power in physical education lessons for university students by George Mocanu, Carmen Parvu, Gabriel Murariu, Dan Szabo

“…These tests were scheduled at three different times during the academic year: October, December, and May. …”
Get full text

Study of the psychometric properties of the HLS-EU-12 questionnaire in rural Bangladesh. by Fakir M Amirul Islam

“…All items were found to have ordered thresholds, suggesting that respondents had no difficulty differentiating between response options on the 4-point Likert-type scale. …”
Get full text

Association between urinary albumin-to-creatinine ratio and all-cause and cardiovascular-cause mortality among MASLD: NHANES 2001–2018 by Zhengjin Wang, Zhangxin Chen, Zhangxin Chen, Hanxu Zhuang

“…The study population was divided into three different risk categories based on urinary UACR: low level (&lt;4.67 mg/g), intermediate level (4.67–7.67 mg/g), and high level (7.68–30 mg/g). …”
Get full text

Adverse birth outcome research case definitions associated with maternal HIV and antiretroviral drug use in pregnancy: a scoping review by Kopano R. Dube, Shani T. de Beer, Kathleen M. Powis, Michael McCaul, Amy L. Slogrove

“…The variations included the use of different thresholds and the addition of new terminology. …”
Get full text

Household-scale anaerobic digestion of food waste—a community case study from Bozeman, Montana by Roland Ebel, Jed Eberly, Bruna Irene Grimberg, Tim Seipel, Fabian D. Menalled

“…Digestate C and N content did not differ between digester models, while different pH (p &lt; 0.05) was observed with a final pH of 6.1 in the commercial small-scale digester and a pH of 5.3 in the custom-built prototype. …”
Get full text

Propionyl Carnitine Metabolic Profile: Optimizing the Newborn Screening Strategy Through Customized Cut-Offs by Maria Lucia Tommolini, Maria Concetta Cufaro, Silvia Valentinuzzi, Ilaria Cicalini, Mirco Zucchelli, Alberto Frisco, Simonetta Simonetti, Michela Perrone Donnorso, Sara Moccia, Ines Bucci, Maurizio Aricò, Vincenzo De Laurenzi, Luca Federici, Damiana Pieragostino, Claudia Rossi

“…Statistical analysis was used to create alarm thresholds for NBS-positive samples. Statistically significant differences were found in both neonatal and maternal conditions based on the 2-TTs carried out. …”
Get full text

Multi-locus transcranial magnetic stimulation with pulse-width modulation by Heikki Sinisalo, Mikael Laine, Jaakko O. Nieminen, Victor H. Souza, Renan H. Matsuda, Ana M. Soto, Elena Ukharova, Tuomas Mutanen, Ilkka Rissanen, Matti Stenroos, Lari M. Koponen, Risto J. Ilmoniemi

“…Objective: To investigate whether multi-coil TMS combined with pulse-width modulation (PWM) in the microsecond scale could be used to overcome the issue of rapid pulse delivery to different cortical targets. Methods: We devised a methodology to generate and drive PWM approximations of given reference pulses. …”
Get full text

Costs-effectiveness and cost components of pharmaceutical and non-pharmaceutical interventions affecting antibiotic resistance outcomes in hospital patients: a systematic literatur... by Hassan Haghparast-Bidgoli, Gerard Joseph Abou Jaoude, Koen B Pouwels, Laith Yakob, Nichola R Naylor, María José Hernández-Leal, Kasim Allel, Eduardo A. Undurraga, Priyanka Bhandari, Ellen Flanagan

“…Country willingness-to-pay (WTP) thresholds from Woods et al 2016 guided cost-effectiveness assessments. …”
Get full text

Analysis of climate variability and its linkage with large-scale climate oscillations: implications to pastoral and agropastoral livelihood resilience in Siti Zone, Somali Region,... by Esayas Nigatu Gebremeskel, Degefa Tolossa, Getachew Gebru

“…Spatiotemporal sea surface temperature was established using the Pearson correlation method. Mann–Kendal and Sen’s slope estimator trend test were also used for trend analysis. …”
Get full text

Supporting antiretroviral therapy uptake and adherence: the SUPA research programme and RCT by Rob Horne, Caroline Sabin, Trudie Chalder, Vanessa Cooper, Lucy Campbell, Elizabeth Glendinning, Iris Mosweu, Paul McCrone

“…The ICER was £9143 per QALY. At a threshold of £20,000 per QALY, there was more than a 90% likelihood that CBT would be more cost-effective than CAU. …”
Get full text

Effectiveness of resistance training of masticatory muscles for patients with temporomandibular disorders: protocol for a systematic review by Deborah Falla, Filippo Maselli, Giacomo Asquini, Andrea Giusti, Giulia Pisacane, Giovanni Galeoto, Firas Mourad, Paolo Bizzarri, Edoardo Balli, Cecilia Bagnoli, Anna Manzari, Marco Pernici

“…This systematic review will evaluate the effectiveness of RT on pain and temporomandibular joint range of motion in people with TMDs.Methods and analysis The report of this protocol aligns with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols. …”
Get full text