Mechanism of Inflammation Regulation of α7nAChR in Spleen and Spinal Dorsal Horn of Mice with Paclitaxel-induced Neuropathic Pain by Electroacupuncture on Zusanli Acupoint by PANG Lina, LAN Yanyan, WANG Zhifu, CHEN Xiaomei, YU Xiangmei

“…The changes of mechanical paw withdrawal threshold (PWT) and paw withdrawal latency (PWL) of mice at day 0, 7 and 14 were measured by Von Frey painometer and a plantar algesia meter, respectively. …”
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Characteristics of Cerebral Cortical Structural Alterations in Female Patients with Systemic Lupus Erythematosus Without Major Neuropsychiatric Manifestations Accompanied by Anxiet... by Zhicheng Liu, Yifan Yang, Shuang Liu, Guofang Zhang, Ru Bai, Shu Li, Ruotong Zhao, Yuqi Cheng, Jian Xu

“…We also further examined the correlation between these morphological alterations and clinical characteristics. Methods: Employing advanced structural MRI (sMRI) techniques, we implemented a dual analytical approach combining voxel-based morphometry (VBM) and surface-based morphometry (SBM) to assess structural differences across three cohorts comprising 59 SLE patients with anxiety and/or depression (SLE-AD), 35 SLE patients with no anxiety and/or depression (SLE-NAD), and 48 age-matched healthy controls (HCs). …”
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Diabetes-related distress and psychological burden in patients with type 1 and type 2 diabetes – the role of child maltreatment, personality functioning, and epistemic trust: findi... by Sandra Zara, Imogen Carla Ullrich, Anna Maria Leveling, Friederike Gisela Genoveva Saretzki, Jana Schmitz, Michael Eckhard, Johannes Kruse, Johannes Kruse, Johannes Kruse, Hanna Kampling, Hanna Kampling

“…Epistemic mistrust and credulity were significantly higher (mistrust: t(111)=3.677, p<.001, d=.692; credulity: t(111)=5.000, p<.001, d=.941), with medium and large effect sizes. No differences regarding epistemic trust were found (t(111)=.409, p=.683, d=.077), with the effect size below the threshold for small effects. …”
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Evidence from high‐income countries on the effectiveness of psychosocial interventions to improve mental health, wellbeing and quality of life for adults living with HIV: a systema... by Ada R. Miltz, Janey Sewell, Fumiyo Nakagawa, Sophia M. Rein, Lorraine Sherr, Alison Rodger, Andrew N. Phillips, Sanne vanLuenen, Nadia Garnefski, Vivian Kraaij, Colette J. Smith, Valentina Cambiano, Fiona C. Lampe

“…A systematic review and meta‐analysis was conducted to address this research gap. Methods Medline, Embase, Psychinfo and Web of science were searched (from 2008 to December 2023). …”
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Bariatric surgery for patients with type 2 diabetes mellitus requiring insulin: Clinical outcome and cost-effectiveness analyses. by Emma Rose McGlone, Iain Carey, Vladica Veličković, Prem Chana, Kamal Mahawar, Rachel L Batterham, James Hopkins, Peter Walton, Robin Kinsman, James Byrne, Shaw Somers, David Kerrigan, Vinod Menon, Cynthia Borg, Ahmed Ahmed, Bruno Sgromo, Chandra Cheruvu, Gul Bano, Catherine Leonard, Howard Thom, Carel W le Roux, Marcus Reddy, Richard Welbourn, Peter Small, Omar A Khan

“…Over 5 years, bariatric surgery was cost saving compared to BMT (total cost GBP£22,057 versus GBP£26,286 respectively, incremental difference GBP£4,229). This was due to lower treatment costs as well as reduced diabetes-related complications costs and increased health benefits. …”
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Accuracy of a 2-minute eye-tracking assessment to differentiate young children with and without autism by Kristelle Hudry, Lacey Chetcuti, Diana Weiting Tan, Alena Clark, Alexandra Aulich, Catherine A. Bent, Cherie C. Green, Jodie Smith, Kathryn Fordyce, Masaru Ninomiya, Atsushi Saito, Shuji Hakoshima, Andrew J. O. Whitehouse

“…Limitations Our groups differed on socio-demographic characteristics and overall tracking (included within the Classification Algorithm). …”
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Classification of Metallic Powder Morphology Using Traditional and Automated Static Image Analysis: A Comparative Study by Cindy Charbonneau, Fabrice Bernier, Étienne Perrault, Roger Pelletier, Louis-Philippe Lefebvre

“…This paper compares results from a particle classification approach using two software programs that work with metallographic images with those from an automated static particle analyzer. While traditional methods offer higher resolution and precision, this study shows that automated systems can achieve similar particle shape classification using different shape descriptors and thresholds.…”
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Pain profiling in migraine: a systematic review of Quantitative Sensory Testing (QST), Conditioned Pain Modulation (CPM), and Corneal Confocal Microscopy (CCM) by Floor Clarissa van Welie, Albert Dahan, Monique van Velzen, Gisela Marie Terwindt

“…A previous meta-analysis reported lower heat pain thresholds (HPT). CPM studies suggest a (mild) inhibitory or absent response in migraine patients, not different from controls. …”
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Preliminary Investigation concerning Metals Bioavailability in Waters of Aries River Catchment by Using the Diffusive Gradients in Thin Films Technique by Marin Senila, Erika Andrea Levei, Lacrimioara Ramona Senila, Marius Roman

“…However, where the metals concentration is near the thresholds values the determination method is very important.…”
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Plasma Epstein-Barr Virus DNA load for diagnostic and prognostic assessment in intestinal Epstein-Barr Virus infection by Chunxiang Ma, Chunxiang Ma, Chunxiang Ma, Mingshan Jiang, Mingshan Jiang, Mingshan Jiang, Jiaxin Li, Jiaxin Li, Jiaxin Li, Zhen Zeng, Zhen Zeng, Zhen Zeng, Yushan Wu, Yushan Wu, Yushan Wu, Rui Cheng, Rui Cheng, Rui Cheng, Hao Lin, Hao Lin, Hao Lin, Jiangmei Pang, Jiangmei Pang, Jiangmei Pang, Fang Yin, Fang Yin, Fang Yin, Yongbin Jia, Yongbin Jia, Yongbin Jia, Lili Li, Lili Li, Lili Li, Hu Zhang, Hu Zhang, Hu Zhang

“…This study aims to identify ideal threshold levels for plasma EBV DNA loads in the diagnosis and outcome prediction of intestinal EBV infection, particularly in cases of primary intestinal lymphoproliferative diseases and inflammatory bowel disease (IBD).MethodsReceiver operating characteristic (ROC) curves were examined to determine suitable thresholds for plasma EBV DNA load in diagnosing intestinal EBV infection and predicting its prognosis.Results108 patients were retrospectively assigned to the test group, while 56 patients were included in the validation group. …”
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Association Between Serum Uric Acid Levels and Skin Cancer: Results from NHANES Data and Mendelian Randomization Analysis by Niu Y, Shi S, Chen Y, Yang S, Yan P, Kou J

“…Risk trends vary at different SUA thresholds, and elevated levels are tied to other negative health outcomes. …”
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Pilot project to study the association of troponin I with cardiovascular events in the population of Russian region by S. A. Shalnova, O. M. Drapkina, A. V. Kontsevaya, E. B. Yarovaya, V. A. Kutsenko, V. A. Metelskaya, A. V. Kapustina, Yu. A. Balanova, O. A. Litinskaya, M. S. Pokrovskaya

“…As part of a pilot study, to investigate the potential significance of cardiac troponin I (cTnI) in assessing the risk of cardiovascular diseases (CVD) in general population aged 35-64 years of one of the regions from the ESSE-RF study.Material and methods. The study is based on the ESSE-RF observational prospective study using a sample from one Russian region. …”
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Growth, physical, and cognitive function in children who are born HIV-free: School-age follow-up of a cluster-randomised trial in rural Zimbabwe. by Joe D Piper, Clever Mazhanga, Marian Mwapaura, Gloria Mapako, Idah Mapurisa, Tsitsi Mashedze, Eunice Munyama, Maria Kuona, Thombizodwa Mashiri, Kundai Sibanda, Dzidzai Matemavi, Monica Tichagwa, Soneni Nyoni, Asinje Saidi, Manasa Mangwende, Dzivaidzo Chidhanguro, Eddington Mpofu, Joice Tome, Gabriel Mbewe, Batsirai Mutasa, Bernard Chasekwa, Handrea Njovo, Chandiwana Nyachowe, Mary Muchekeza, Kuda Mutasa, Virginia Sauramba, Ceri Evans, Melissa J Gladstone, Jonathan C Wells, Elizabeth Allen, Melanie Smuk, Jean H Humphrey, Lisa F Langhaug, Naume V Tavengwa, Robert Ntozini, Andrew J Prendergast

“…The school achievement test score was 39.0 (SD 26.0) in CBHF and 45.7 (27.8) in CHU (mean difference 7.3 points [95% CI 3.6, 10.9]; p < 0.001); differences remained significant in adjusted analyses. …”
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Kidney Beam-A Cost-Effective Digital Intervention to Improve Mental Health by Sharlene A. Greenwood, Juliet Briggs, Christy Walklin, Emmanuel Mangahis, Hannah M.L. Young, Ellen M. Castle, Roseanne E. Billany, Elham Asgari, Sunil Bhandari, Nicolette Bishop, Kate Bramham, James O. Burton, Jackie Campbell, Joseph Chilcot, Nicola Cooper, Vashist Deelchand, Matthew P.M. Graham-Brown, Lynda Haggis, Alexander Hamilton, Mark Jesky, Philip A. Kalra, Pelagia Koufaki, Kieran McCafferty, Andrew C. Nixon, Helen Noble, Zoe L. Saynor, Maarten W. Taal, James Tollitt, David C. Wheeler, Thomas J. Wilkinson, Hannah Worboys, Jamie Macdonald

“…Results: At 6-months, there was a significant difference in mean adjusted change in KDQoL MCS score between Kidney BEAM and waitlist control (intention-to-treat adjusted mean: 5.9 [95% confidence interval, CI: 4.4–7.5] arbitrary units [AU], P < 0.0001), and a 93% and 98% chance of the intervention being cost-effective at a willingness-to-pay threshold of £20,000 and £30,000 per quality-adjusted life year gained. …”
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Sensibilidade vibratória: valor semiótico em algumas afecções do sistema nervoso by Horacio Martins Canelas

“…The average vibration perception thresholds of the left side of the body were lesser than those of the right side, although only in the great toes the difference was statistically significant. 9. …”
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Diagnostic Principles of Peri-Implantitis: a Systematic Review and Guidelines for Peri-Implantitis Diagnosis Proposal by Ausra Ramanauskaite, Gintaras Juodzbalys

“…In all of the papers, different definitions of peri-implantitis or implant success, as well as different thresholds for the above mentioned clinical and radiographical parameters, were used. …”
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Baseline pulmonary hypertension in heart transplant recipients: 9 years of experience at Almazov National Medical Research Centre by M. A. Simonenko, G. V. Nikolayev, K. N. Malikov, P. A. Fedotov, Y. V. Sazonova, M. A. Bortsova, V. E. Rubinchik, A. O. Marichev, A. E. Bautin, M. Y. Sitnikova, M. L. Gordeev, M. A. Karpenko

“…Objective: to assess the impact of baseline pulmonary hypertension (PH) on early and long-term outcomes following heart transplantation (HT). Materials and methods. From January 2010 to December 2018, 112 HTs were carried out. …”
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Agreement between a photogrammetry-derived five-compartment body-composition model and a three-compartment criterion among adult athletes by Kworweinski Lafontant, Claudia Gonzalez, Michelle Da Silva Barbera, Susan Kampiyil, Linh Nguyen, Sofea Smith, Jack Livingston, Jeffrey R. Stout, David H. Fukuda

“…All statistical analyses were conducted using the “blandr” package within jamovi, and the threshold for statistical significance was set at p < 0.05.Results Body volume from the BodPod (74.4 ± 15.1 L) significantly differed from the Fit3D®’s estimate (72.6 ± 14.7 L; bias = 1.81 L; 95% CI = 1.28, 2.34 L; LoA = −1.91,5.53 L p < 0.001). …”
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A study of relationship between cardiac exposure dose-volume and cardiovascular autonomic dysfunction in radiotherapy by CHEN Hongyu, SU Pengyu, LUO Wenzi, PANG Dequan, WANG Feiran

“…However, there are currently few relevant studies on the effect of radiotherapy on cardiac autonomic function, and the specific injury effects and dose threshold of injury occurrence remain unclear. This study aimed to explore the impact of thoracic radiotherapy on the cardiac autonomic function of patients with malignant tumors by comparing the differences in heart rate variability (HRV) analysis parameters before and after radiotherapy, and to explore the dosimetric risk factors for the occurrence of AD by comparing the dosimetry between the case group and the control group, providing a theoretical basis for optimizing the dose distribution of radiotherapy regimens in order to improve patient prognosis and reduce the occurrence of complications. …”
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Cirrus formation regimes – data-driven identification and quantification of mineral dust effect by K. Jeggle, D. Neubauer, H. Binder, U. Lohmann

“…</p> <p>Our results provide an observational line of evidence that the climate intervention method of seeding cirrus clouds with potent INPs may potentially result in an undesired positive cloud radiative effect (CRE), i.e., a warming effect. …”
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