Absolute risk-based versus individualized benefit approaches for determining statin eligibility in primary prevention of cardiovascular diseases in Chinese populations: A modeling... by Qiuping Liu, Chao Gong, Tianjing Zhou, Minglu Zhang, Xiaofei Liu, Xun Tang, Pei Gao

“…We estimated eligible populations, CVD events averted, and number needed to treat (NNT) both at population and individual level (iNNT) over 10 years versus no treatment, assessed discordance, and primarily calibrated the benefit threshold to match event prevention by the risk-based approach for comparison. …”
Get full text

Environmental pollution and human fertility: investigating the relationship between PM2.5 exposure and assisted reproductive technology outcomes by Fei Li, Xiaoyan Duan, Mingming Li, Yumei Gao, Yuejuan Kang, WenJun Zheng, XueYan Guo, Ying Chen

“…GAM analysis further identified a nonlinear, threshold-like association between pregnancy outcomes and predictive factors, with significantly higher live birth rates observed in spring, summer, and autumn compared to winter. …”
Get full text

Obesity indicators mediate the association between the aggregate index of systemic inflammation (AISI) and type 2 diabetes mellitus (T2DM) by Ziying Su, Lei Cao, Hailong Chen, Peng Zhang, Chunwei Wu, Jing Lu, Ze He

“…Furthermore, it evaluates the mediating effect of obesity indicators on this association. Methods This study included 9,947 individuals from NHANES and applied appropriate weighting techniques. …”
Get full text

N-terminal propeptide of type III procollagen for predicting diastolic dysfunction in patients with myocardial infarction and preserved ejection fraction by A. V. Osokina, V. N. Karetnikova, O. M. Polikutina, A. V. Ivanova, O. E. Avramenko, O, V. Gruzdeva, O. L. Barbarash

“…To study changes in the level of fibrotic scarring marker — the N-terminal propeptide type III procollagen (PIIINP) and structural and functional parameters with the assessment of diastolic function in patients a year after ST segment elevation myocardial infarction (STEMI) and preserved left ventricle (LV) contractility.Material and methods. At first, the study included 120 (100%) STEMI patients. …”
Get full text

Building a risk prediction model for anastomotic leakage postoperative low rectal cancer based on Lasso-Logistic regression by Zhenhao Quan, Lin Lin, Renwei Huang, Kaiyu Sun, Feipeng Xu

“…H-L goodness of fit test showed that there was no significant difference between the predicted value of the model and the actual observed value (χ 2  = 6.438, P = 0.598). …”
Get full text

Predictive symptoms for COVID-19 in the community: REACT-1 study of over 1 million people. by Joshua Elliott, Matthew Whitaker, Barbara Bodinier, Oliver Eales, Steven Riley, Helen Ward, Graham Cooke, Ara Darzi, Marc Chadeau-Hyam, Paul Elliott

“…Viral genome sequencing was carried out for PCR-positive samples with N-gene cycle threshold value < 34 (N = 1,079) in round 8 (January 2021). …”
Get full text

Skin/Muscle Incision and Retraction Induces Evoked and Spontaneous Pain in Mice by Juan Yang, Fei Yuan, Gang Ye, Yong-Jie Wang, Cheng Wu, Jinghua Wang, Xiang-Yao Li, Zhiying Feng

“…The paw withdrawal threshold (PWT) to mechanical stimuli and the paw withdrawal latency to heat stimuli were measured before and after SMIR. …”
Get full text

Performance of PREVENT and pooled cohort equations for predicting 10-Year ASCVD risk in the UK Biobank by Matthew Ambrosio, Pamela L. Alebna, Terence Lee, Alec Friedman, Nicholas WS Chew, Carolyn Burns, Phillip Duncan, W. Gregory Hundley, Le Kang, Anurag Mehta

“…Conclusions: There is no significant difference in 10-year ASCVD risk discrimination between PCE and PREVENT equations. …”
Get full text

Clinical outcomes of limited open reduction and intramedullary nailing with steel cable cerclage in Seinsheimer III femoral subtrochanteric fractures by Hongru Cai, Hongru Cai, Hongru Cai, Hongru Cai, Hongru Cai, XueYi He, XueYi He, XueYi He, XueYi He, XueYi He, Zhengchao Zhang, Zhengchao Zhang, Zhengchao Zhang, Zhengchao Zhang, Zhengchao Zhang, Pinhua Chen, Pinhua Chen, Pinhua Chen, Pinhua Chen, Pinhua Chen, Ruoli Wang, Ruoli Wang, Ruoli Wang, Ruoli Wang, Ruoli Wang, Qi Fang, Qi Fang, Qi Fang, Qi Fang, Qi Fang, Zhixian Xu, Zhixian Xu, Zhixian Xu, Zhixian Xu, Zhixian Xu, Wubing He, Wubing He, Wubing He, Wubing He, Wubing He

“…Statistical analyses were performed using SPSS 26.0, with a significance threshold of p &lt; 0.05.ResultsThe observation group experienced significantly less intraoperative blood loss (p &lt; 0.001) and shorter hospital stays (p &lt; 0.001), with no difference in operation time (p = 0.996). …”
Get full text

All-Suture Anchor Techniques for Biceps Tenodesis Are Noninferior in End-Cycle Stiffness to an Interference Screw Technique; However, Secondary Outcomes, Such as Ultimate Failure L... by Kendal Carter, M.D., Emily Rogers, B.S., Nicholas J. Peterman, B.S., Vincent Wang, Ph.D., John R. Tuttle, M.D.

“…End-cycle stiffness difference-of-means testing was conducted with a minimal clinically important difference threshold of –15 N/mm (–1.5 kg/mm). …”
Get full text

Perception of illusory vowels by Persian speakers in several consonant clusters of French loanwords by Saghar Javidpour, Aliyeh Kord Zafaranlu kambuziya, Mandana Nourbakhsh

“…Since this is below the conventional threshold of 0.05, it can be inferred that there is a statistically significant difference in the frequency of heard vowels among initial, medial, and final consonant clusters. …”
Get full text

Evaluation of intestinal tissue safety during the compression process of circular end-to-end anastomosis stapler based on finite element simulation by Yuanda Zhou, Yuanda Zhou, Yuanda Zhou, Yuanda Zhou, Zhen Tan, Peishi Jiang, Yi Sun, Yi Sun, Yi Sun, Yi Sun, Dewang Wu

“…ObjectiveCurrently, there is no standardized finite element analysis method for investigating the safe compression range of circular end-to-end anastomosis stapler. …”
Get full text

Can Synthetic Data Allow for Smaller Sample Sizes in Chronic Urticaria Research? by Annika Gutsche, Pascale Salameh, Samad S. Jahandideh, Mehran Roodsaz, Serkan Kutan, Ali Salehzadeh‐Yazdi, Emek Kocatürk, Stamatios Gregoriou, Simon F. Thomsen, Kanokvalai Kulthanan, Papapit Tuchinda, Joachim Dissemond, Alicja Kasperska‐Zajac, Magdalena Zajac, Mateusz Zamłyński, Martijn vanDoorn, Claudio A. S. Parisi, Jonny G. Peter, Cascia Day, Cathryn McDougall, Michael Makris, Daria Fomina, Elena Kovalkova, Nikolai Streliaev, Gerelma Andrenova, Marina Lebedkina, Maryam Khoskhkui, Mehraneh M. Aliabadi, Andrea Bauer, Lea Kiefer, Melba Muñoz, Karsten Weller, Pavel Kolkhir, Martin Metz

“…Known associations and correlations between disease‐specific factors (disease control) and risk factors (age) yielded similar results, with no significant difference (p > 0.05). The lowest threshold at which synthetic data could be generated while maintaining high accuracy in RWD was identified to be 25%, enabling a fourfold increase in the synthetic population. …”
Get full text

CLINICAL SIGNIFICANCE OF DETERMINING THE LEVEL OF THE BRAIN NATRIURETIC PEPTIDE FOR THE DIAGNOSIS OF HEART FAILURE OF COMORBID PATIENTS WITH CORONARY HEART DISEASE AND THYROTOXICOS... by E. V. Pashchenko, A. I. Chesnikova, V. I. Kudinov, V. P. Terent’ev

“…The following research methods were used in the work: the clinical state assessment scale (CSAS), the 6-minute walk test (6MWT), echocardiography. …”
Get full text

Detection of Body Packs in Abdominal CT scans Through Artificial Intelligence; Developing a Machine Learning-based Model by Sayed Masoud Hosseini, Seyed Ali Mohtarami, Shahin Shadnia, Mitra Rahimi, Peyman Erfan Talab Evini, Babak Mostafazadeh, Azadeh Memarian, Elmira Heidarli

“…Our proposed Body Packs Detection (BPD) model achieved a mean average precision (mAP) value of 86.6% when the intersection over union (IoU) was 0.5, and a mAP value of 45.6% at different IoU thresholds (from 0.5 to 0.95 in steps of 0.05). …”
Get full text

Research Framework and Anticipated Outcomes of Flash Flood Disasters Due to the Combined Effects of Extreme Rainfall and Intense Human Activities by Xiekang WANG

“…This involves establishing simulation methods for meteorological, hydrological, and sediment dynamic processes, identifying the risks of flash flood erosion, deposition, and inundation in mountainous areas, and developing methods to identify prone areas for different types of flash floods. …”
Get full text

Prevalence of Active and Latent Yaws in the Solomon Islands 18 Months after Azithromycin Mass Drug Administration for Trachoma. by Michael Marks, Oliver Sokana, Eli Nachamkin, Elliot Puiahi, Georgina Kilua, Allan Pillay, Christian Bottomley, Anthony W Solomon, David C Mabey

“…The TPPA seroprevalence amongst this age group did not differ significantly from either our pre-mass treatment survey or our initial follow-up survey. …”
Get full text

Customized e-nose sensor array configuration and VOCs pattern analysis for Cabernet Sauvignon grape post-harvest quality monitoring by Quansheng Dou, Yuchen Ning, Bingxi Chen, Guangfen Wei, Jing Liu

“…Traditional quality assessment methods, which rely on expert sensory evaluation, are inherently subjective and impractical for large-scale operations. …”
Get full text

Curvatura vertical de vertentes em microbacias pela análise de modelos digitais de elevação Curvature slope profile in watersheds through analysis of digital elevation models by Márcio de M. Valeriano

“…Contour-based kriged DEM of six watersheds from different terrain types and with varied data specifications were used for the tests. …”
Get full text

Improved Soybean Mapping with Spectral Gaussian Mixture Modeling by Guilong Xiao, Kaiqi Du, Shuangxi Miao, Xuecao Li, Anne Gobin, Tiecheng Bai, Miao Zhang, Bingfang Wu, Jianxi Huang

“…Moreover, it identifies an accurate soybean mapping timeframe, named the optimal time window, to refine spectral feature extraction across varying environmental conditions and crop calendars. Unlike previous methods that rely on fixed thresholds or a limited set of spectral indices, our SGMM offers a probabilistic mapping framework that dynamically adapts to regional variations in soybean growth. …”
Get full text