Biological Variation of Corrected QT and QRS Electrocardiogram Intervals: Interpreting Results of Drug-induced Prolongation by Alan Wu, Kayla Kendric, Caitlin Roake, Emily Kelly

“…Introduction: Toxicologists use a universal threshold to determine QRS and QTc prolongation in poisoned patients. …”
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Advection-Free Convolutional Neural Network for Convective Rainfall Nowcasting by Jenna Ritvanen, Bent Harnist, Miguel Aldana, Terhi Makinen, Seppo Pulkkinen

“…However, current precipitation nowcasting methods based on the extrapolation of radar echoes have a limited ability to predict the growth and decay of rainfall. …”
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Impact of ultraviolet radiation on filtering facepiece respirators and SARS-CoV-2 detection by Khaled Al-Hadyan, Najla Al-Harbi, Sara Bin Judia, Maha Al-Ghamdi, Ibtihaj Alsharif, Layla Alharbi, Maha Al-Mozaini, Belal Moftah, Belal Moftah, Salem Al-Ghamdi, Ghazi Alsbeih, Ghazi Alsbeih

“…This study aims to evaluate the impact of UV-C irradiation on the filtration efficiency (FE) of various FFR types and SARS-CoV-2 RNA degradation.MethodWe evaluated the effect of UV-C irradiation (60–900 mJ/cm2) on the FE using various particle sizes (PSs, 0.3–5 μm) representing seven common FFR types (3M-8210, 3M-1860, Gerson 1730, Medline, Benehal, KN95 “duck shape,” and KN95 “molded shape”) and the stability of the SARS-CoV-2 RNA genes (E, RdRp2, RdRp4, and N) using reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR).ResultsFollowing UV-C exposure, the FE of the FFRs at all PSs was >98%, with no significant differences among them (p > 0.05). …”
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A retrospective cross-sectional study of association between triglyceride-glucose index and carotid atherosclerosis by Congfang Guo, Mingming Li, Lili Wang, Yuting Bai, Yudong Rong, Minying Zhang, Fenghua Guo, Xiang Guo, Jie Guo, Li Zhang, Yiyan Zhao

“…Linear relationships between TyG index and CA were showed in different subgroups stratified by age, gender and different metabolic conditions and overweight/obesity individals.ConclusionThe TyG index is a significantly association of CA, particularly in high-risk subgroups. …”
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The burden of acute respiratory infection attributable to fine particulate matter brought by dust storms among children under 5 years of age in low- and middle-income countries by Hong Lu, Mingkun Tong, Ruohan Wang, Ning Kang, Xueqiu Ni, Jianyu Deng, Jiajianghui Li, Pengfei Li, Tianjia Guan, Tong Zhu, Tao Xue

“…We also used the spline method to develop a dust-specific ERF. Based on the function, we estimated the burden of dust-associated U5-ARI across 100 LMICs and compared it with the results from two well-established functions of total PM2.5 mass. …”
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Cropping system is a key determinant of soil health after accounting for environmental and edaphic variability by Franky Celestin, Gabriel Maltais-Landry, Jose C.B. Dubeux, Rao S. Mylavarapu, Yang Lin

“…The effects of cropping system on soil health indicators remained statistically meaningful after propensity score weighting using the same significance threshold (α = 0.05). Soil organic matter and carbon-related indicators were consistently higher in grazed pastures than in row crop systems, indicating that differences in disturbance and management intensity across cropping systems regulated soil health. …”
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Expression and clinical significance of S100A8/9 in adults with secondary phagocytic lymphohistiocytosis by Ziwei Fang, Xin Gao, Limin Duan, Jujuan Wang, Tian Tian, Ji Xu, Yongqian Shu, Guangli Yin, Hongxia Qiu

“…The optimal classification threshold for S100A8/9 was determined to be 2.44 µg/mL by restricted cubic spline (RCS) curve analysis. …”
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Efficacy and cost-effectiveness analysis of 10-day versus 14-day eradication of Helicobacter pylori infection with vonoprazan amoxicillin: a prospective, multicenter, randomized co... by Yunfan Dong, Zhaotao Duan, Min Liu, Yanbing Ding, Guangxia Chen, Ruifang Wang, Xiaodan Xu, Lixia Ding, Qiang Zhan, Chengyu Pan, Hui Li, Faming Yang, Xiaorong Dai, Xiangsu Li, Xudong Wu, Peng Peng, Jianrong Wang, Kewei Hu, Duanmin Hu, Qiong Jie, Zhenyu Zhang

“…ObjectivesTo evaluate the efficacy and cost-effectiveness of 10-day vonoprazan-amoxicillin (VA) dual therapy compared to 14-day VA therapy.MethodsA non-inferiority trial was carried out at 10 clinical centers to recruit patients with H. pylori infection. …”
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Albumin: a novel biomarker for predicting intraoperative hypothermia in HSCR by Xiaohui Huang, Mobai Ren, Junrong Pan, Ene Huang, Yanhong Li, Donghao Guo, Junjie Wang

“…ROC analysis was applied to determine the optimal threshold for ALB.Results In this retrospective study, 71 patients had intraoperative non-hypothermia and 14 patients had intraoperative hypothermia (83.5% versus 16.5%). …”
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The effect of post-exercise heat exposure (passive heat acclimation) on endurance exercise performance: a systematic review and meta-analysis by Thomas P. J. Solomon, Matthew J. Laye

“…Therefore, we synthesised a systematic review and meta-analysis to answer whether post-exercise heat exposure improves exercise performance. Methods Five databases were searched to identify studies including: (i) healthy adults; (ii) an exercise training intervention with post-exercise heat exposure via sauna or hot water immersion (treatment group); (iii) a non-heat exposure control group completing the same training; and (iv) outcomes measuring exercise performance in the heat (primary outcome), or performance in thermoneutral conditions, V̇O2max, lactate threshold, economy, heart rate, RPE, core temperature, sweat rate, and thermal sensations. …”
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Influence of systemic immunoinflammatory index on major adverse cardiovascular events in patients with coronary heart disease with heart failure as assessed by propensity score mat... by ZhiRong Ren, JinWen Liu

“…The ROC curve showed that the area under the curve (AUC) of SII after PSM was 0.788 (95% CI 0.714–0.860, P < 0.001), with an optimal threshold of 589.31 (sensitivity 81.58%, specificity 65.79%). …”
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Objective Tools for Assessing the Probability of Acute Appendicitis in Domestic Practice by P. A. Kotkov, B. V. Sigua, S. V. Petrov, A. A. Kozobin, I. L. Esayan, A. A. Chekirov, V. P. Zemlyanoy

“…The final diagnostic accuracy for all analyzed classifiers did not differ statistically significantly and was at acceptable levels of 78.8%, 76.7%, 76.7%, and 75.7% for the AIRS, Ripasa, AAS, and Alvarado scales, respectively (p=0.115). …”
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R&D Expenditure and Innovation in the EU and Selected Member States by Radka MacGregor Pelikánová

“…This generates a set of original suggestions, such as that the differences between EU member states regarding innovations do not vanish and that although the Europe 2020 3% threshold is not met, the number of patented inventions and the practical digitalization can still grow across the EU. …”
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The predictive value of endplate morphology and pedicle screw bone quality score on screw loosening after single-level lumbar spinal fusion surgery by Jinxiang Zhan, Qipeng Wei, Weijun Guo, Zihao Liu, Shiji Chen, Qingyan Huang, Dongling Cai

“…The AUC for the PBQ score was 0.791 (95% CI: 0.729–0.844), with an optimal threshold of 3.198 (sensitivity: 91.2%, specificity: 61.8%). …”
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Uncovering the link between cardiometabolic index and depression in diabetes: a large-scale population study by Nuo Ma, Jiasuer. Alifu, Guilin Meng, Jiangping Ma, Haichao Wang, Xiulin Meng, Xueyuan Liu

“…Depression risk increased significantly below this threshold but plateaued beyond it, suggesting a threshold effect primarily within the moderate to high CMI range. …”
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Hyperuricaemia elevates risk of short-term readmission and mortality in patients with heart failure by Haibo Chen, Wei Wen, Jiahuan Rao, Ruihui Lai, Lingyan Jiang

“…Participants with HF were categorised into normouricaemia group (NUA) and hyperuricaemia group (HUA) based on a SUA threshold of 420 µmol/L. The association between SUA and primary endpoint was evaluated using Kaplan-Meier survival curves and Cox regression analysis.Results Baseline characteristics revealed significant differences between NUA and HUA groups, with the latter exhibiting a higher prevalence of males, chronic kidney disease (CKD) and elevated levels of various biomarkers. …”
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Estimation of lifetime survival and predictors of mortality among TB with HIV co-infected children after test and treat strategies launched in Northwest, Ethiopia, 2021; a multicen... by Ermias Sisay Chanie, Getnet Asmare Gelaye, Tesfaye Yimer Tadesse, Dejen Getaneh Feleke, Wubet Taklual Admas, Eshetie Molla Alemu, Melkalem Mamoye Azanaw, Sofonyas Abebaw Tiruneh, Alemayehu Digssie Gebremariam, Binyam Minuye Birhane, Wubet Alebachew Bayih, Getachew Aragie

“…The risk of mortality among TB and HIV co-infected children was associated with treatment failure, CD4 count below the threshold, and cotrimoxazole preventive therapy non-users. …”
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Effects of a Low-Dose Cardiac Rehabilitation Program on Cardiovascular Conditioning Parameters in Patients with Heart Disease by Pablo Reyes, Quirino Mejía Melara, José Onan Saldívar Ramírez, José Solís, Fernando Tienda López, Ramiro Flores Ramírez

“…AIM: To evaluate the effects of low-dose cardiac rehabilitation on cardiovascular performance parameters in patients with heart disease. METHODS: A longitudinal, retrospective, observational, and analytical study was conducted. …”
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Performance of the early warning system score in predicting postoperative complications in older versus younger patients by Annick Stolze, Lisette Vernooij, Dianne de Korte-de Boer, Markus W. Hollmann, Wolfgang F. F. A. Buhre, Christa Boer, Peter G. Noordzij, the TRACE Study Investigators Group

“…Missed event rates (proportion of events not detected by the EWS threshold) and nonevent rates (proportion of EWS values above the threshold without an adverse event) were calculated. …”
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Effect of Simple Myopic Astigmatism and Its Axis on Near Visual Performance for Thai Alphabet in Pseudophakic Eyes by Pakviwat P, Moollaong C, Borvonshivabhumi S, Roongpoovapatr V

“…This study investigated the effect of astigmatism and its axis on distance and near visual acuity (VA), and near visual performance for the Thai alphabet using the Thai MNREAD chart.Design: Investigational simulation.Methods: Distance (6.0 m) VA, near (40 cm) VA and near visual performance (maximum reading speed [MRS], threshold print size [TPS] and reading acuity [RA]), were assessed by the Thai MNREAD chart monocularly in 31 pseudophakic eyes (62.8 ± 8.55 years). …”
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