Investigation of the impact of commonly used medications on the oral microbiome of individuals living without major chronic conditions. by Vanessa DeClercq, Jacob T Nearing, Morgan G I Langille

“…Alpha diversity indices of Shannon diversity, Evenness, Richness, and Faith's phylogenetic diversity were similar among groups, likewise beta diversity as measured by Bray-Curtis dissimilarity (R2 = 0.0029, P = 0.053) and weighted UniFrac distances (R2 = 0.0028, P = 0.161) were non-significant although close to our alpha value threshold (P = 0.05). After controlling for covariates (sex, age, BMI), six genera (Saprospiraceae uncultured, Bacillus, Johnsonella, Actinobacillus, Stenotrophomonas, and Mycoplasma) were significantly different from non-medication users. …”
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Glycaemic control, low levels of high-density lipoprotein, and high cardiovascular risk are associated with cardiovascular autonomic neuropathy by Tina Okdahl, Anne-Marie Wegeberg, Marie Møller Jensen, Jonas Salling Quist, Christina Brock

“…The purpose of this study was to compare CAN status in people with and without diabetes and to investigate which factors contributed the most to the presence and severity of CAN. Methods We included 240 participants from three different cohorts: non-diabetic people (n = 40), people with overweight or obesity with or without prediabetes (n = 100), and people with type 2 diabetes (n = 100). …”
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Changes in left ventricular systolic and diastolic function after chemotherapy for breast cancer with doxorubicin by I. A. Karput, V. A. Snezhitskii, M. N. Kurbat, V. A. Gorustovich, Yu. I. Karpovich, A. Yu. Rubinskii, T. A. Smirnova, A. S. Babenka

“…Depending on the choice of the threshold level of relative reduction in global longitudinal strain (GLS) in %, different median values were recorded in the subgroups with and without CT (before and after chemotherapy). …”
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Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE) by Sarah Mendorf, Sarah Mendorf, Konstantin G. Heimrich, Hannah M. Mühlhammer, Hannah M. Mühlhammer, Tino Prell, Tino Prell, Aline Schönenberg

“…Clinically relevant changes were defined via the minimal clinically important difference (MCID). We applied linear regression and linear mixed models (LMM) to explore predictors of QoL trajectories.ResultsDescriptive analyses showed that 2481 PoA (19.7%) experienced stable QoL between waves, based on changes below the MCID threshold of 3.18 points. …”
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Mitochondrial DNA in day 3 culture medium as a molecular biomarker of human embryo fragmentation, aneuploidy, and implantation competency by Shymaa F. A. Abdellatif, Asmaa A. A. Hussein, Ahmed A. Youssef

“…Abstract Aim This study aims to use the mitochondrial DNA (mtDNA) in day 3 culture medium (D3CM) as a molecular biomarker of intracytoplasmic sperm injection (ICSI) and preimplantation genetic testing outcome. Methods This prospective observational study was performed using 49 embryos from 9 patients, which were individually cultured after ICSI. …”
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The questions on violence (FOV) tool for interpersonal violence inquiry in Swedish healthcare settings – evaluation of content validity, face validity and test-retest reliability by Solveig Lövestad, Karin Sjöström, Josefin Björk, Karin Örmon

“…The average content validity index of included items was 0.88, which is slightly below the recommended threshold for excellent content validity. The results based on the cognitive interviews revealed that participants found the seven items to be relevant and easy to understand. …”
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Comparison of Ultrasound-Based Techniques and Magnetic Resonance Imaging Proton Density Fat Fraction in Measuring the Amount of Hepatic Fat in Children with Hepatosteatosis by Sabriye Gulcin BOZBEYOGLU, Murat ASIK

“…Methods: The study group consisted of pediatric patients under 18 years of age without known liver disease who volunteered to participate. …”
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Common obesity-related anthropometric indices and the risk of gestational diabetes mellitus in a Chinese population: a prospective cohort study by Hong Wang, Lun Sui, Qian Xu, Minyu Li, Yuhan Xing, Guoju Li

“…Pregnant women with VAT above the optimal threshold (27.05 mm) might benefit from targeted GDM monitoring.…”
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The association between dietary mineral intake and bone mineral density: a cross-sectional study by Muyou Wei, Junjiang Wei, Shengsheng Huang

“…Smooth curve fitting and threshold effect analyses further demonstrated nonlinear relationships between mineral intakes and BMD. …”
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Inflammatory Activity in Patients with Obstructive and Non-obstructive Coronary Artery Disease by N. N. Pakhtusov, A. O. Yusupova, A. S. Lishuta, O. A. Slepova, E. V. Privalova, Yu. N. Belenkov

“…To study the levels of pro-inflammatory biomarkers  in patients with obstructive  and non-obstructive coronary  artery disease (CAD), to identify possible differences  for diagnosing the degree of coronary  obstruction.Material and methods. …”
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Pathogenetic and substitution correction of anemia in patients with malignant neoplasms by N. A. Romanenko, A. E. Alborov, S. S. Bessmeltsev, E. R. Shilova, S. V. Voloshin, A. V. Chechetkin

“…This datum suggests presence of tissue hypoxia and gives approval to expand the threshold for red blood cells transfusions…”
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Spontaneous Adverse Drug Reaction Reporting of Congenital Malformations: A Danish National Register Study by Ulrik Lausten-Thomsen, Rasmus Huan Olsen, Michael Christiansen, Paula L. Hedley, Ida Marie Heerfordt, Jon Trærup Andersen, Christina Gade

“…Given the potential underreporting, we encourage a low threshold for reporting ADRs based on suspicion alone, with final causality assessments made by health authorities.…”
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Unilateral remote temperature monitoring to predict future ulceration for the diabetic foot in remission by David G Armstrong, Lawrence A Lavery, Brian J Petersen, David R Linders, Jonathan D Bloom, Gary M Rothenberg

“…The purpose of this study was to assess the sensitivity, specificity, and lead time associated with unilateral diabetic foot temperature monitoring.Research design and methods We used comparisons among ipsilateral foot temperatures and between foot temperatures and ambient temperature as a marker of inflammation. …”
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Removal of calcium hydroxide from simulated internal root resorption defects: a comparative evaluation of EDDY, iVac, Pulp sucker, passive ultrasonic irigation, and conventional te... by Burçin Arıcan, Nihan Berkdemir, Ayşe Tuba Özalp Koca, Utku Can Kemeç, Taha Özyürek

“…However, no significant difference was found between PS and CSI (p > 0.05). …”
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Changes in motor cortex excitability associated with muscle fatigue in patients with Parkinson's disease by Milanović Slađan, Filipović Saša R., Radovanović Saša, Blesić Suzana, Ilić Nela V., Kostić Vladimir S., Ljubisavljević Miloš R.

“…The aim of this study was to examine changes in responses to TMS in patients suffering from Parkinson’s disease (PD) during sustained submaximal isometric voluntary contraction [60% of maximal voluntary contraction (MVC)] of the adductor pollicis muscle, as well as during a subsequent recovery period. Methods. Cortical excitability was tested by single TMS pulses of twice of the motor threshold intensity applied over the vertex. …”
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Cardiopulmonary exercise testing in aortic stenosis patients before and after aortic valve replacement by Kristofer Hedman, Eva Nylander, Éva Tamás, Carl Bellander, Henric Nilsson

“…Mean peak oxygen uptake (peakVO2) was not significantly different between PRE and POST; 1871±441 vs 1937±404 mL/min (p=0.08). …”
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Comparison of ultrasound and dynamic MRI for the measurement of diaphragmatic excursion: A prospective single-center study. by Clara Delplancke, Etienne Charpentier, François Grolleau, Anne Hernigou, Hélène Nougué, Françoise Le Pimpec-Barthes, Bernard Cholley, Matthieu Daniel

“…<h4>Methods</h4>Prospective single-center study in which consecutive outpatients referred for a dynamic thoracic MRI were included. …”
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CD4 enumeration technologies: a systematic review of test performance for determining eligibility for antiretroviral therapy. by Rosanna W Peeling, Kimberly A Sollis, Sarah Glover, Suzanne M Crowe, Alan L Landay, Ben Cheng, David Barnett, Thomas N Denny, Thomas J Spira, Wendy S Stevens, Siobhan Crowley, Shaffiq Essajee, Marco Vitoria, Nathan Ford

“…We conducted a systematic review of the performance of technologies for CD4 enumeration.<h4>Methods and findings</h4>Studies were identified by searching electronic databases MEDLINE and EMBASE using a pre-defined search strategy. …”
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Enhancing yield and nutritional quality of sweet potato through genotype selection and selenium application by Qing Liao, Ying Xing, Li-Ping Pan, Jin-Ping Chen, Yong-Xian Liu, Dong-Liang Huang

“…In addition, the effects of different Se application methods and dosages, soil application (10 L/hm2 and 20 L/hm2), foliar spraying (1.5 L/hm2 and 3.0 L/hm2), and combined soil and foliar application, were investigated on yield and quality parameters in two representative varieties: Guiziweishu 1 (high Se accumulator) and Fushu 404 (low Se accumulator). …”
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Effectiveness of maximum, explosive and combined strength training on endurance runners performance indicators: a systematic review and meta-analysis by PABLO PRIETO GONZALEZ, Fatma H. Yagin, Jorge Sánchez-Infante, Luca Paolo Ardigò

“…Methods: A systematic review (Scopus, Web of Science, Sports Discuss, PubMed) with meta-analysis was conducted following PRISMA standards. …”
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