Behaviour-based movement cut-off points in 3-year old children comparing wrist- with hip-worn actigraphs MW8 and GT3X. by Daniel Jansson, Rikard Westlander, Jonas Sandlund, Christina E West, Magnus Domellöf, Katharina Wulff

“…This study aimed at (i) calibrating activity counts of motor behaviour measured simultaneously with MotionWatch 8 (MW8) and ActiGraph (GT3X) in 3-year-old children, (ii) documenting movement intensities in 30s-epochs at wrist/hip positions, and (iii) evaluating the accuracy of cut-off agreements between different behavioural activities.<h4>Methods</h4>Thirty 3-year-old children of the NorthPop cohort performed six directed behavioural activities individually, each for 8-10 minutes while wearing two pairs of devices at hip and wrist position. …”
Get full text

Muscle matters: Skeletal muscle index and body mass index impact on complications and survival in renal cancer by Alexander Hintze Hillers, Signe Wang Bach, Atena Saito, Nessn Azawi

“…Abstract Objective The objective of this study is to independently assess skeletal muscle index (SMI) and body mass index (BMI) as prognostic determinants for renal cell carcinoma (RCC) and investigate their correlation with surgical outcomes. Patients and methods A retrospective cohort study of 524 RCC patients diagnosed between August 2010 and July 2018 was conducted using data from the Zealand University Hospital Renal Cancer Database in Denmark. …”
Get full text

The effects of transitioning from SITA-Standard to SITA-Fast or SITA-Faster on sensitivities below the measurement floor by Chris Bradley, Alex Pham, Jithin Yohannan

“…Design: Retrospective descriptive study Participants: A total of 21,468 24-2 SITA-Standard, 4872 SITA-Fast and 3468 SITA-Faster VFs from 7917 glaucoma and glaucoma suspect eyes with at least 5 VFs between 1997 and 2023 at the Wilmer Eye Institute. Methods: At each test location of the 24-2 test pattern, we measured the probability that <0 dB at a given test location on two baseline SITA-Standard VFs was M dB or higher on the first SITA-Fast or SITA-Faster post-baseline VF for different values of M > 0. …”
Get full text

Integrating Drone Truthing and Functional Classification of Remote Sensing Time Series for Supervised Vegetation Mapping by Giacomo Quattrini, Simone Pesaresi, Nicole Hofmann, Adriano Mancini, Simona Casavecchia

“…These datasets improved classification accuracy by ensuring a comprehensive representation of vegetation spectral variability, enabling the classifier to identify the key phenological patterns that best characterize and distinguish different vegetation types across the landscape. The proposed methodology achieves a classification accuracy of 92.59%, significantly exceeding the commonly reported thresholds for habitat mapping. …”
Get full text

A clear distinction and presence of Acropora aff. divaricata within Acropora cf. solitaryensis species complex along their biogeographic distribution in East Asia by Savanna Wenhua Chow, Chih-Hsun Chen, Du-Yang Tsai, Takuma Mezaki, Satoshi Kubota, Hernyi Justin Hsieh, Shashank Keshavmurthy, Chaolun Allen Chen

“…Abstract In the Anthropocene, scleractinian corals face unprecedented threats from synergistic stressors, including rising seawater temperatures that surpass critical thresholds that lead to global coral reef degradation. …”
Get full text

Abstract 078: Managing Clopidogrel Resistance in Neurointervention: Surveying Current Approaches by Hyun Woo Kim, Ivo Bach, Juan Carlos Martinez‐Gutierrez, Adam Dmytriw, Hussein Zeineddine, Salvatore D'Amato, Sunil Sheth

“…Respondents reported 25 different therapeutic thresholds, with the P2Y12 Reaction Units range between 60 and 180 most commonly used (16.4%). 61% reported they would switch to ticagrelor in the case of persistent resistance. …”
Get full text

Performance with an additional load: formula-based predictions for controlling the load intensity when carrying backpacks by Saskia Klughardt, Bettina Schaar

“…Conclusion The formulas can predict the adaptation of running speeds and heart rates at the ventilatory thresholds with different additional loads. This is useful for controlling optimal load intensities in endurance performance with additional loads, to prevent overstraining. …”
Get full text

Automated note annotation after bioacoustic classification: Unsupervised clustering of extracted acoustic features improves detection of a cryptic owl by Callan Alexander, Robert Clemens, Paul Roe, Susan Fuller

“…The pipeline helps to address two key challenges in bioacoustic monitoring: the need for manual validation of automated detections and the difficulty of obtaining accurate note-level annotations in noisy field recordings. Adaptation of these methods to other species and vocalisations may facilitate improved detection and investigation of vocal characteristics across different populations or regions.…”
Get full text

The Influence of Insertion Torque on Stress Distribution in Peri-Implant Bones Around Ultra-Short Implants: An FEA Study by Mario Ceddia, Lorenzo Montesani, Luca Comuzzi, Alessandro Cipollina, Douglas A. Deporter, Natalia Di Pietro, Bartolomeo Trentadue

“…However, the amount of insertion torque (IT) applied during implant placement significantly influences stress distribution in the peri-implant bone, which affects implant stability and long-term success. Materials and Methods: This study used finite element analysis (FEA) to examine how different insertion torques (35 N·cm and 75 N·cm) affect stress distribution in cortical and trabecular bone types D2 and D4 surrounding ultra-short implants. …”
Get full text

De novo genome hybrid assembly and annotation of the endangered and euryhaline fish Aphanius iberus (Valenciennes, 1846) with identification of genes potentially involved in salini... by Alfonso López-Solano, Ignacio Doadrio, Tessa Lynn Nester, Silvia Perea

“…In addition to the assembly, an extensive functional annotation of the genome is provided by using AUGUSTUS, and two different approaches (InterProScan and Sma3s). The genome size (1.15 Gb) is consistent with that of the most closely related species, and its quality and completeness, as assessed with various methods, exceeded the suggested minimum thresholds, thus confirming the robustness of the assembly. …”
Get full text

Establishing the best step-up treatments for children with uncontrolled asthma despite inhaled corticosteroids: the EINSTEIN systematic review, network meta-analysis and cost-effec... by Sofia Cividini, Ian Sinha, Giovanna Culeddu, Sarah Donegan, Michelle Maden, Katie Rose, Olivia Fulton, Dyfrig Hughes, Stephen Turner, Catrin Tudur Smith

“…A cost-effectiveness curve was generated to depict the probability of each intervention being cost-effective at different willingness-to-pay thresholds. Results We identified and screened 4708 publications from the search and retrieved 508 full-text articles for eligibility assessment. …”
Get full text

Integrative radiomics of intra- and peri-tumoral features for enhanced risk prediction in thymic tumors: a multimodal analysis of tumor microenvironment contributions by Liang zhu, Jiamin Li, Xuefeng Wang, Yan He, Siyuan Li, Shuyan He, Biao Deng

“…To further evaluate the effectiveness of these models, various statistical methods were applied, including DeLong’s test, NRI, and IDI, to compare predictive differences among models. …”
Get full text

Validating the pathogenic mechanism of chronic obstructive pulmonary disease induced by negative emotions via Mendelian randomization and traditional Chinese medicine theory of emo... by Zhiying Wang, Yun Li, Zhixian Zhong, Ling Xu, Yi Zhong, Jian Chen

“…Objective: We employed Mendelian randomization (MR) to test the traditional Chinese medicine (TCM) theory of emotional pathogenesis concept and explore the causal relationship between negative emotions and chronic obstructive pulmonary disease (COPD). Methods: Data of negative emotions, bronchitis, emphysema, and C-reactive protein (CRP) levels were downloaded from genome-wide association study (GWAS) public database for a two-sample MR analysis. …”
Get full text

Sensibilidade vibratória: valor semiótico em algumas afecções do sistema nervoso by Horacio Martins Canelas

“…The average vibration perception thresholds of the left side of the body were lesser than those of the right side, although only in the great toes the difference was statistically significant. 9. …”
Get full text

An echo state network based on enhanced intersecting cortical model for discrete chaotic system prediction by Xubin Wang, Pei Ma, Jing Lian, Jizhao Liu, Yide Ma

“…The model incorporates a neuron model with internal dynamics, including adaptive thresholds and inter-neuron feedback, into the reservoir structure. …”
Get full text

Epicardial Adipose Tissue and Heterogeneity Parameters Combined with Inflammatory Cells to Predict the Value of Heart Failure with Preserved Ejection Fraction Patients Post Myocard... by Yu-jiao Song, Xiao-ying Zhao, Lu-jing Wang, Ting Ning, Ming-tian Chen, Pei Liu, Si-wen Chen, Xin-xiang Zhao

“…The optimal cut-off values were identified using time-dependent ROC curves in R software, and Kaplan–Meier event-survival curves were plotted to illustrate the event-free rates based on these optimal thresholds.The median follow-up time was calculated using the reverse Kaplan–Meier method. …”
Get full text

Exploring voluntary sector specialist services for victim-survivors of sexual violence in England: the PROSPER co-production study by Caroline Bradbury-Jones, Sarah Damery, Kirsten Fruin, Clare Gunby, Jenny Harlock, Lucy Hebberts, Louise Isham, Anne-Marie Jones, Fay Maxted, Amelia Mighty, Priti Parmar, Laura Patterson, Jason Schaub, Fee Scott, Harriet Smailes, Debs Smith, Julie Taylor

“…Explore the usefulness of different approaches to service delivery and different therapy models. …”
Get full text

Identification and Cross-Platform Validation of Sparse Molecular Classifiers for Antibody-Mediated and T-Cell–Mediated Rejection After Kidney Transplantation by Jasper Callemeyn, Josué Manik Nava-Sedeño, Dany Anglicheau, Jack Beadle, Jan Hinrich Bräsen, Marian C. Clahsen-van Groningen, Iacopo Cristoferi, Henriette de Loor, Andreas Deutsch, Marie Essig, Wilfried Gwinner, Philip F. Halloran, Dennis A. Hesselink, Priyanka Koshy, Dirk Kuypers, Evelyne Lerut, Pierre Marquet, Robert C. Minnee, Candice Roufosse, Ben Sprangers, Amaryllis H. Van Craenenbroeck, Haralampos Hatzikirou, Maarten Naesens

“…Herein, we aimed to develop and validate sparse molecular classifiers for ABMR and TCMR using allograft tissue. Methods: In a discovery cohort of 224 kidney transplant biopsies, lasso regression was applied on microarray gene expression data to derive a molecular classifier for ABMR and TCMR, respectively. …”
Get full text

The relationship between glucose patterns in OGTT and adverse pregnancy outcomes in twin pregnancies by Wei‐Zhen Tang, Qin‐Yu Cai, Yi‐Fan Zhao, Hao‐wen Chen, Xia Lan, Xia Li, Li Wen, Ying‐Xiong Wang, Tai‐Hang Liu, Lan Wang

“…Abstract Background Traditional fixed thresholds for oral glucose tolerance test (OGTT) results may inadequately prevent adverse pregnancy outcomes in twin pregnancies. …”
Get full text

Imaging modalities for characterising T1 renal tumours: A systematic review and meta‐analysis of diagnostic accuracy by Hannah Warren, Jack B. Fanshawe, Valerie Mok, Priyanka Iyer, Vinson Wai‐Shun Chan, Richard Hesketh, Eleanor Zimmermann, Veeru Kasivisvanathan, Mark Emberton, Maxine G. B. Tran, Kurinchi Gurusamy

“…Meta‐analysis was not performed for other imaging due to different thresholds for test positivity. Conclusion The optimal imaging strategy for T1 renal masses is not clear. [99mTc]Tc‐sestamibi SPECT/CT is an emerging tool, but further studies are required to inform its role in clinical practice. …”
Get full text