Study Protocol: Potential Role of β-Carotene to Improve Reprogramming of Cardiac Fuel Preferences in Premature Newborns by Olupathage C Dinesh

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Androgens drive SLC1A5-dependent metabolic reprogramming in polycystic ovary syndrome by Yishu Wang, Jiaying Wu, Gaochen Zhang, Yan Shi, Yicong Meng, Pingping Lv, Weiwei Huang, Yunfei Su, Zhiyang Zhou, Bo Wang, Xiaojun Chen, Chengliang Zhou, Jiexue Pan, Li Jin, Xiaotao Wang, Yanting Wu, Jianzhong Sheng, Xinmei Liu, Yu Zhang, Guolian Ding, Chuanjin Yu, Hefeng Huang

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Bisphenol A causes melatonin biosynthesis epigenetic reprogramming of melatonin biosynthesis genes in arabidopsis thaliana by Yu Zheng, Chun Bao, Jingxian Fang, Bolei Chen, Xiaoxi Yang, Jianbo Shi, Meiling Su, Zhenting Li, Yun Yin, Changli Zeng, Yong Liang

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Metabolic Reprograming of Macrophages: A New Direction in Traditional Chinese Medicine for Treating Liver Failure by Junli Zhang, Na Li, Xiaoyu Hu

“…Macrophages play a crucial role in the initiation, development, and recovery of ALF. Targeting macrophages through immunotherapy holds significant promise as a therapeutic strategy. …”
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Epigenetic Reprogramming of Cell Identity in the Rat Primary Neuron–Glia Cultures Involves Histone Serotonylation by Anastasia A. Borodinova, Yulia A. Leontovich, Alexander P. Beletskiy, Alexander V. Revishchin, Galina V. Pavlova, Pavel M. Balaban

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Crosstalk between the tumor immune microenvironment and metabolic reprogramming in pancreatic cancer: new frontiers in immunotherapy by Taijin Shi, Xiaoyan Cui, Junlin Wang, Guangqia Liu, Jiayin Meng, Yingjie Zhang

“…In the future, targeting specific mechanisms of metabolic reprogramming will provide a solid theoretical basis for the development of combination therapies for PC.…”
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Metabolic reprogramming of peritoneal mesothelial cells in peritoneal dialysis–associated fibrosis: therapeutic targets and strategies by Fang Yu, Jia Chen, Xiaoyue Wang, Shihui Hou, Hong Li, Yaru Yao, Yani He, Kehong Chen

“…However, prolonged PD use can lead to the development of peritoneal fibrosis (PF), diminishing its efficacy. …”
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Metabolic Reprogramming in Autosomal Dominant Polycystic Kidney Disease: Role in Cystogenesis and Novel Therapeutic Approaches by Jingyuan Gao, Xiaoyong Yu

“…A comprehensive understanding of these mechanisms may contribute to the development of innovative treatment methods aiming to slow the disease progression of patients with ADPKD.…”
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Convergent and divergent transcriptional reprogramming of motor and sensory neurons underlying response to peripheral nerve injury by Jian Yang, Shuqiang Zhang, Xiaodi Li, Zhifeng Chen, Jie Xu, Jing Chen, Ya Tan, Guicai Li, Bin Yu, Xiaosong Gu, Lian Xu

“…It also identified some novel regeneration-associated candidates that may facilitate the development of strategies for axon regeneration.…”
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Characterization of Metabolic Reprogramming in Head and Neck Squamous Cell Carcinoma and Application Prospects for Targeted Therapy by Ruilin WANG, Yuxiu MA, Xuelin LIU, Qi ZHANG, Guoyin WANG, Hongling LI

“…Thus, discovering more effective diagnostic and therapeutic approaches is an urgent need. The metabolic reprogramming of tumor cells is a key feature in the development of HNSCC, which widely exhibits alterations in glycolytic metabolism, lipid metabolism, and amino acid metabolism compared with normal cells. …”
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Hypoxia-induced metabolic reprogramming in mesenchymal stem cells: unlocking the regenerative potential of secreted factors by Wendy V. Jaraba-Álvarez, Ashanti C. Uscanga-Palomeque, Vanesa Sanchez-Giraldo, Claudia Madrid, Hector Ortega-Arellano, Karolynn Halpert, Karolynn Halpert, Carolina Quintero-Gil

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Mechanochemically reprogrammed porous tantalum with synergistic antibacterial and osteogenic properties for the treatment of infectious bone defects by Yan Sun, Yu Zhang, Kai Zhang, Jiangyu Nan, Zixuan Xiong, Wenbin Liu, Yihe Hu, Pengfei Lei

“…In this study, we employed magnetron sputtering technology to modify ZnO particles on the surface of tantalum nanotubes (TaNTs) in porous tantalum, which were mechanochemically reprogrammed to enhance their properties. This approach enabled functionalization without altering the surface microstructure, resulting in the development of a ZnO-modified tantalum nanotube array coating (TaNTs@ZnO) designed to address infection. …”
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Baicalin mitigates alcoholic-associated liver disease via SOCS1-driven reprogramming of macrophages by Sha Huang, Yuhua Wang, Jinjie Wen, Wenjuan Ji, Qiuxiang Zeng, Kaili Deng, Min Li, Shanshan Kuang, Wen Zhang, Mo Chan, Chuying Zhou, Zhiping Lv, Shaohui Huang

“…Conclusion In conclusion, our findings suggest that BA attenuates ALD via the modulation of SOCS1-mediated macrophage reprogramming.…”
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EGFR‐TKIs Induced DPP4 Drives Metabolic Reprogramming of Persister Cells in Lung Cancer by Yuanzhou Zhang, Xiaojun Zhang, Xupeng Yang, Xingshi Chen, Yuehong Wang, Jingying Hu, Rui Liu, Xiaoying Luo

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Mitochondrial dysfunction and metabolic reprogramming in acute kidney injury: mechanisms, therapeutic advances, and clinical challenges by Meiling Cao, Xueqi Zhao, Fang Xia, Mingyue Shi, Danyang Zhao, Lei Li, Hongkun Jiang

“…This adaptive metabolic reprogramming is frequently associated with the activation of the pentose phosphate pathway and the suppression of gluconeogenesis. …”
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Metabolomic reprogramming of the tumor microenvironment by dual arginase inhibitor OATD-02 boosts anticancer immunity by Marcin Mikołaj Grzybowski, Yasemin Uçal, Angelika Muchowicz, Tomasz Rejczak, Agnieszka Kikulska, Katarzyna Maria Głuchowska, Małgorzata Szostakowska-Rodzoś, Agnieszka Zagożdżon, Tobias Bausbacher, Agnieszka Tkaczyk, Magdalena Kulma, Paulina Pomper, Michał Mlącki, Adam Konrad Jagielski, Roman Błaszczyk, Carsten Hopf, Zbigniew Zasłona

“…The observed metabolic reprogramming, coupled with enhanced immune activation and prolonged survival, supports the clinical development of OATD-02 as a promising strategy for enhancing cancer immunotherapy efficacy. …”
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Tumor-colonizing Pseudoalteromonas elyakovii metabolically reprograms the tumor microenvironment and promotes breast ductal carcinoma by Shuyan Liu, Youpeng Pan, Chaopeng Zheng, Qinghui Zheng, Yaoqiang Du, Yajuan Zheng, Hongchao Tang, Xiaozhen Liu, Jiancheng Mou, Xin Zeng, Zhuotao Yang, Wenjuan Gui, Yuning Tang, Mingxing Xu, Zhihao Ye, Haotian Su, Qiuran Xu, Xuli Meng

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Histone modifications and metabolic reprogramming in tumor-associated macrophages: a potential target of tumor immunotherapy by Yiting Xu, Han Zhang, Dengyun Nie

“…This review explores the role of histone modifications in TAM biology, their interplay with metabolic reprogramming, and the opportunities and challenges in developing epigenetic-based therapies to advance cancer immunotherapy.…”
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Sequential Release HydroLipo System for STING Gene Epigenetic Reprogramming and Immune Activation in Glioblastoma by Hao Yu, Wenjing Liu, Kaikai Ding, Jiangjie Wu, Cheng Wang, Siyuan Wang, Lingyun Wu, Qiuying Tang, Xin Yin, Kan Jiang, Danfang Yan, Xu Wang, Si Chen, Senxiang Yan

“…To overcome this clinical limitation, a Sequential Release HydroLipo System (SRHLS) is developed, in which hydrogels and nanoparticles are combined for controlled drug release. …”
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Aging affects reprogramming of pulmonary capillary endothelial cells after lung injury in male mice by Marin Truchi, Marine Gautier-Isola, Grégoire Savary, Célia Scribe, Arun Lingampally, Hugo Cadis, Alberto Baeri, Virginie Magnone, Cédric Girard-Riboulleau, Marie-Jeanne Arguel, Clémentine de Schutter, Julien Fassy, Nihad Boukrout, Romain Larrue, Nathalie Martin, Roger Rezzonico, Olivier Pluquet, Michael Perrais, Véronique Hofman, Charles-Hugo Marquette, Paul Hofman, Andreas Günther, Nicolas Ricard, Pascal Barbry, Sylvie Leroy, Kevin Lebrigand, Saverio Bellusci, Christelle Cauffiez, Georges Vassaux, Nicolas Pottier, Bernard Mari

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