Immune signaling mediates stromal changes to support epithelial reprogramming in celiac duodenum by Dylan Richards, Klebea Sohn, Shrikanth Chomanahalli Basavarajappa, Daniel Horowitz, Joshua Rusbuldt, Lynn Tomsho, Kate Paget, Ivan Chavez, Koen Van den Berge, Brad McRae, Heather Loughnane, Seamus Hussey, Patrick Walsh, Darren Ruane

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Cardiac Niche Influences the Direct Reprogramming of Canine Fibroblasts into Cardiomyocyte-Like Cells by Giacomo Palazzolo, Mattia Quattrocelli, Jaan Toelen, Roberto Dominici, Luigi Anastasia, Guido Tettamenti, Inès Barthelemy, Stephane Blot, Rik Gijsbers, Marco Cassano, Maurilio Sampaolesi

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Intermittent Fasting Improves Aging Immunity by Reprogramming Systemic Myeloid Lineage and Tissue Inflammation by Hye Won Han, Zheng Shen, Da Mi Kim, Hongying Wang, Zeyu Liu, Yuxiang Sun

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The glucose metabolism reprogramming of yak Sertoli cells under hypoxia is regulated by autophagy by Rui MA, Yan CUI, Si-Jiu YU, Yang-Yang PAN, Jun-feng HE, Ya-ying WANG, Jing-lei WANG, Xiao-yan WANG, Xue-feng BAI, Hui ZHANG, Shan-shan YANG, Qian ZHANG

“…Glucose metabolic reprogramming is an important way for cells to respond to stressful environments, especially the metabolite lactate, which is the energy basis for the development and differentiation of germ cells. …”
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Calcium Channel Blocker Lacidipine Promotes Antitumor Immunity by Reprogramming Tryptophan Metabolism by Yuwen Sheng, Chong Qiao, Zhonghui Zhang, Xiaoke Shi, Linhan Yang, Ruiying Xi, Jialing Yu, Wanli Liu, Guolin Zhang, Fei Wang

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COUP-TFII-mediated reprogramming of the vascular endothelium counteracts tumor immune evasion by Yu Zhu, Kevin F. Brulois, Thanh T. Dinh, Junliang Pan, Eugene C. Butcher

“…We show that ectopic pan-endothelial expression of COUP-TFII, a master transcription factor for venous development, induces molecular programs of post-capillary venules in tumor endothelium. …”
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Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia. by Nicolas Bonadies, Samuel D Foster, Wai-In Chan, Brynn T Kvinlaug, Dominik Spensberger, Mark A Dawson, Elaine Spooncer, Anthony D Whetton, Andrew J Bannister, Brian J Huntly, Berthold Göttgens

“…In particular, downregulation of Gata2 expression was mirrored by abundant GATA motifs in regions of reduced histone acetylation suggesting an important role in leukaemogenic transcriptional reprogramming. Forced re-expression of Gata2 was not compatible with sustained growth of leukaemic cells thus suggesting a previously unrecognised role for Gata2 in downregulation during the development of AML. …”
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A super versatile flexizyme system with phenol esters for genetic code reprogramming by Yun-Kyu Choi, Takayuki Katoh, Adam Beattie, Hiroaki Suga

“…Abstract Genetic code reprogramming enables ribosomal incorporation of multiple nonproteinogenic amino acids (npAAs), supporting bioactive peptide development. …”
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UHRF2 mediates resistance to DNA methylation reprogramming in primordial germ cells by Ambre Bender, Marion Morel, Michael Dumas, Muriel Klopfenstein, Naël Osmani, Maxim V. C. Greenberg, Déborah Bourc’his, Norbert B. Ghyselinck, Michael Weber

“…Here we report that resistance to DNA methylation reprogramming in PGCs requires UHRF2, the paralog of the DNMT1 cofactor UHRF1. …”
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Mitochondrial morphology and energy metabolism in reprogrammed porcine expanded potential stem cells by Yun Ju Lee, Jae Hoon Song, Je Woo Lee, Tae Kyung Hong, Sang Jun Uhm, Kwonho Hong, Jeong Tae Do

“…In this study, we successfully generated porcine EPSCs (pEPSCs). Methods We reprogrammed porcine fetal fibroblasts (PFFs) using an integration-free method with Sendai virus vectors. …”
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Chemical reprogramming culture for the expansion of salivary gland epithelial basal progenitor cells by Ye Jin Jeong, Yongpyo Hong, Yeo-Jun Yoon, Nam Suk Sim, Seung-Min Hong, Jae-Yol Lim

“…This advancement holds significant promise for the development of SG epithelial progenitor-based therapies to treat SG hypofunction.…”
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Indole-3-lactic acid suppresses colorectal cancer via metabolic reprogramming by Shizhen Zhou, Kai Wang, Jiandong Huang, Zhen Xu, Qinggang Yuan, Lixiang Liu, Zhifeng Wang, Ji Miao, Hao Wang, Tingting Wang, Wenxian Guan, Chao Ding

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Metabolic reprogramming and prognostic insights in molecular landscapes driven by glycolysis in ovarian cancer by Mingwei Wang, Qiaohui Ying, Yuncan Xing, Shuchang Dai, Jue Wang, Zhong Liu

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Metabolic reprogramming by PRDM16 drives cytarabine resistance in acute myeloid leukemia by Junji Ikeda, Hiroyoshi Kunimoto, Yusuke Saito, Shin-Ichi Tsujimoto, Masanobu Takeuchi, Ayaka Miura, Takayuki Kurosawa, Koichi Murakami, Ikuma Kato, Megumi Funakoshi-Tago, Akihiko Yokoyama, Norio Shiba, Souichi Adachi, Daisuke Tomizawa, Tomohiko Tamura, Shuichi Ito, Hideaki Nakajima

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Epigenetic dysregulation-induced metabolic reprogramming fuels tumor progression in bladder cancer by Jian Zhang, Xiaosong Fan, Xu Xu, Yichao Han, Weixing Yu, Bicheng Yang, Yanling Chen, Shaolin Zhang

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Parkinson's disease motor symptoms rescue by CRISPRa‐reprogramming astrocytes into GABAergic neurons by Jessica Giehrl‐Schwab, Florian Giesert, Benedict Rauser, Chu Lan Lao, Sina Hembach, Sandrine Lefort, Ignacio L Ibarra, Christina Koupourtidou, Malte Daniel Luecken, Dong‐Jiunn Jeffery Truong, Judith Fischer‐Sternjak, Giacomo Masserdotti, Nilima Prakash, Jovica Ninkovic, Sabine M Hölter, Daniela M Vogt Weisenhorn, Fabian J Theis, Magdalena Götz, Wolfgang Wurst

“…Abstract Direct reprogramming based on genetic factors resembles a promising strategy to replace lost cells in degenerative diseases such as Parkinson's disease. …”
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Reprogramming tumor-associated macrophages in gastric cancer: a pathway to enhanced immunotherapy by Yibo He, Qianran Hong, Shiliang Chen, Jiayi Zhou, Shengliang Qiu

“…Innovations in nanotechnology, metabolic reprogramming, and targeting key pathways such as interleukin-6 and C-C motif ligand 2/C-C motif chemokine receptor 2 further enhance these strategies. …”
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The Emerging Roles of Metabolic Reprogramming in Non-Small Cell Lung Cancer Progression by Beatriz P. Peixoto, Rebecca A. Clague, Joshua P. Reddy, Hiromi I. Wettersten

“…This review explores recent advances in understanding metabolic reprogramming in non-small cell lung cancer (NSCLC), focusing on its critical role in cancer progression. …”
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Tumorigenic Cell Reprogramming and Cancer Plasticity: Interplay between Signaling, Microenvironment, and Epigenetics by Vittoria Poli, Luca Fagnocchi, Alessio Zippo

“…CSCs can originate from normal committed cells which undergo tumor-reprogramming processes and reacquire a stem cell-like phenotype. …”
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The Role of Pattern Recognition Receptors in Epigenetic and Metabolic Reprogramming: Insights into Trained Immunity by Li Y, Chen M, Li J, Hu J

“…By elucidating these processes, our analysis establishes a conceptual framework for developing immunomodulatory therapies and leveraging trained immunity in precision medicine applications.Keywords: pattern recognition receptors, epigenetic, metabolic reprogramming, trained immunity, immunocyte…”
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