Formation of friable embryogenic callus in cassava is enhanced under conditions of reduced nitrate, potassium and phosphate. by Yoshinori Utsumi, Chikako Utsumi, Maho Tanaka, Vu The Ha, Akihiro Matsui, Satoshi Takahashi, Motoaki Seki

“…It might contribute to development of an efficient transformation strategy in cassava.…”
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Synergy of oncolytic adenovirus and immune checkpoint inhibitors: transforming cancer immunotherapy paradigms by Chong Cheng, Qingzhe Wang, Shuang Zhang

“…We propose a strategic framework for optimizing the development and clinical trial design of these combination therapies to advance precision immunotherapy.…”
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ARM-X: an adaptable mesenchymal stromal cell-based vaccination platform suitable for solid tumors by Jean Pierre Bikorimana, Nehme El-Hachem, Gabrielle A. Mandl, Daniela Stanga, Jamilah Abusarah, Roudy Farah, Marina P. Gonçalves, Perla Matar, Malak Lahrichi, Sebastien Talbot, Moutih Rafei

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mSphere of Influence: The integral art of resolving host-virus interactions by Elliott D. SoRelle

“…He incorporates themes from music and visual arts into a discussion of how three publications entitled “The cybernetics of development” by C. H. Waddington (The Strategy of the Genes, chapter 2, https://doi.org/10.4324/9781315765471), “Epstein-Barr viral productive amplification reprograms nuclear architecture, DNA replication, and histone deposition” by Y.…”
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The RNA revolution in medicine: from gene regulation to clinical therapeutics by Jiwon Jeong, Sunjoo Jeong

“…Technological innovations and deeper insights into RNA regulation have transformed the field, positioning RNA as a powerful tool for therapeutic development. Recent advances in RNA technologies have revolutionized medicine by enabling the precise targeting of specific mRNAs to modulate aberrant transcripts, correct genetic defects, and reprogram cellular behavior. …”
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Castilian and Others: The Language Situation in Today’s Spain by A. N. Kozhanovsky

“…According to critics, local authorities promote these policies to eliminate Spanish from schooling in order to «linguistically reprogram» the local population and isolate it from the Spanish cultural and historical heritage. …”
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SLC25A42 promotes gastric cancer growth by conferring ferroptosis resistance through enhancing CPT2-mediated fatty acid oxidation by Haoying Wang, Weijia Dou, Mengxiao Liu, Weifang Wang, Ying Yang, Jibin Li, Zhenxiong Liu, Nan Wang

“…Abstract Accumulating evidence has shown that the dysfunction of mitochondria, the multifunctional organelles in various cellular processes, is a pivotal event in the development of various diseases, including human cancers. …”
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Nuclear accumulation of host transcripts during Zika Virus Infection. by Kristoffer E Leon, Mir M Khalid, Ryan A Flynn, Krystal A Fontaine, Thong T Nguyen, G Renuka Kumar, Camille R Simoneau, Sakshi Tomar, David Jimenez-Morales, Mariah Dunlap, Julia Kaye, Priya S Shah, Steven Finkbeiner, Nevan J Krogan, Carolyn Bertozzi, Jan E Carette, Melanie Ott

“…Multiple pathways involved in normal brain development are dysfunctional in infected NPCs but how ZIKV centrally reprograms these pathways remains unknown. …”
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STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy by Laura Gehrcken, Christophe Deben, Evelien Smits, Jonas R.M. Van Audenaerde

“…This resistance has driven the development of several drug candidates, including stimulators of interferon genes (STING) agonists to reprogram the immune system to fight off tumors. …”
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Mechanical cues orchestrate monocyte behavior in immune regulation and disease by Yifan Lin, Hardik Makkar, Shuchen Zhang, Bingling Chen, Chaoning Zhan, Kyle Vining

“…Additionally, future directions toward developing mechanotherapy for immune modulation are discussed. …”
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PARP1-NFATc1-PD1 pathway of maturation and stability of CD8+T cells is beneficial against chronic Trypanosoma cruzi infection by Imran H. Chowdhury, Nandadeva Lokugamage, Nisha J. Garg

“…Parp1−/− enhanced the maturation and stability of metabolically reprogrammed CD8+ effector and memory T cells with increased cytotoxic effects against the parasite. …”
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BMAL1 in Astrocytes: A Protective Role in Alzheimer’s and Parkinson’s Disease by David Brash-Arias, Luis I. García, Gonzalo Aranda-Abreu, Rebeca Toledo-Cárdenas, César Pérez-Estudillo, Donaji Chi-Castañeda

“…Bmal1 deletion in astrocytes reprograms endolysosomal transcriptional pathways, inducing endocytosis, lysosomal degradation, and autophagic activity. …”
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Targeting myeloid cells to improve cancer immune therapy by Hui Chen, Hui Chen, Zihan Xu, Judith Varner, Judith Varner

“…We examine preclinical and clinical findings that support targeting these pathways to reprogram the TME and enhance anti-tumor immunity. …”
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Neurobehavioral plasticity in the rodent gustatory system induced by regular consumption of a low-calorie sweetener during adolescence by Clare M. Mathes, Sarah J. Terrill, Juan P. Taborda-Bejarano, Sandrine Chometton, Mallory J. Witt, Gaurikka Mendiratta, Emily G. Gilman, Delenn R. Hartswick, Bo M. Anderson, Lindsey A. Schier

“…Here, we investigated if exposure to the LCS Acesulfame Potassium (Ace-K) during this critical period of development reprograms the taste system in a way that would alter hedonic responding for common dietary compounds. …”
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High-resolution transcriptome atlas of bladder cancer highlights the functional myeloid subsets in modulating immune microenvironmentResearch in context by Jiachen Liu, Zhen Shi, Yajian Li, Jie Ma, Jiaying Yao, Zan Yuan, Yuanhao Wang, Chunyuan Yang, Xiao Li, Nianzeng Xing, Yunping Zhu, Jianhong Zhang, Li Wu

“…Funding: National Natural Science Foundation of China (31991174); the National Key Research and Development Program of China (2021YFA1301603 and 2023YFC2507000); the National Basic Science Center Program of China (82388101); the National Key Research and Development Program of China (2019YFA0508502 and 2022YFC2505001).…”
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Injury-induced KIF4A neural expression and its role in Schwann cell proliferation suggest a dual function for this kinesin in neural regeneration by Patrícia D. Correia, Bárbara M. de Sousa, Jesús Chato-Astrain, Joana Paes de Faria, Veronica Estrada, João B. Relvas, Hans W. Müller, Víctor Carriel, Frank Bosse, Sandra I. Vieira

“…Our study further demonstrates that KIF4A levels are greatly increased in Schwann cells from injured distal nerve stumps, particularly at a time when they are reprogrammed into an essential proliferative repair phenotype. …”
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Emerging Multifunctional Biomaterials for Addressing Drug Resistance in Cancer by Mohamed El-Tanani, Syed Arman Rabbani, Rasha Babiker, Yahia El-Tanani, Shakta Mani Satyam, Thantrira Porntaveetus

“…Catalytic biomaterials generate reactive oxygen species (ROS), activate prodrugs, reprogram hypoxic and acidic TME, and degrade the extracellular matrix (ECM) to improve drug penetration. …”
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Metabolomic profiles impacted by brief mindfulness intervention with contributions to improved health by Yi-Yuan Tang, Jeffrey S. Patterson, Rongxiang Tang, Jinhua Chi, Ngoc Bao Phuong Ho, Dorothy D. Sears, Haiwei Gu

“…These findings may guide the development of future mindfulness-based health promotion strategies.…”
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Exosomes in hypoxia: generation, secretion, and physiological roles in cancer progression by Yufeng Mu, Mengrui Yang, Jingyang Liu, Yan Yao, Huimin Sun, Jing Zhuang, Jing Zhuang

“…Acting as nanoscale molecular envoys, exosomes transport oncogenic cargoes (including non-coding RNAs, mutated proteins, and metabolites) to reprogram stromal cells, prime pre-metastatic niches, and establish tumor-host metabolic symbiosis. …”
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MARCO expression on myeloid-derived suppressor cells is essential for their differentiation and immunosuppression by Sijia Liu, Binle Tian, Na Wang, Zhilong Wang, Wen Zhang, Qi Li, JianFei Wang, Guo-Huang Fan, Caicun Zhou

“…In vivo, MARCO down-regulating antibody suppressed tumor growth and reprogrammed the TME by diminishing immunosuppressive MDSCs and TAMs and revitalizing CD8+ T cells and NK cells. …”
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