Use of Sentinel-2 images for the detection of sandbars along the Lower Vistula by Klaudia Oktawia Kryniecka, Artur Magnuszewski

“…Aim of the study: The aim of this paper was to develop and test detection methods of sandbars for a selected section of the Lower Vistula river with the use of Sentinel-2 Level 2A optical images. …”
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Interplay between bile acids, gut microbiota, and the tumor immune microenvironment: mechanistic insights and therapeutic strategies by Yan Tong, Xiaojun Lou

“…Future directions highlighted include tackling heterogeneity, employing advanced multi-omics, and developing robust biomarkers for precision immuno-oncology. …”
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Harnessing beta-cell replication: advancing molecular insights to regenerative therapies in diabetes by Rupangi C. Vasavada, Sangeeta Dhawan

“…There has been tremendous progress in developing approaches that simultaneously promote beta-cell expansion and function. …”
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Bioengineering a Human Dermal Equivalent Using Induced Pluripotent Stem Cell-Derived Fibroblasts to Support the Formation of a Full-Thickness Skin Construct by Lucy Smith, David Bunton, Michael Finch, Stefan Przyborski

“…Pluripotent stem cell-derived populations offer a consistent supply, as well as the ability to model disease phenotypes through cell reprogramming using patient-derived cells. In this study, we have used an induced pluripotent stem cell-derived fibroblast population to develop a dermal equivalent model. …”
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Generation of patient-derived induced pluripotent stem cell line UJSi004-A from ultra-treatment-resistant schizophrenia by Siyu Xi, Bing Xue, Yupeng Wang, Zhenghua Shan, Tianchi Song, Jing Sun, Shengying Qin

“…This iPSC cell line carries the genetic information of the patient and is a good model for studying disease mechanisms and developing new therapies.…”
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Commercial Hoverboard Reverse Engineering and Repurposing for a Stabilized Platform: A Recyclable Solution for Modular Robotic Bases by Antoine Leblanc, Lùka Tricot, Duncan Briquet, Mohamed Aziz Slama, Christophe Delebarre

“…Our methodology involves disassembling and reprogramming the hoverboard’s motor controllers and sensors to maintain horizontal stability. …”
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The role and potential mechanisms of exosomes in the progression of hepatocellular carcinoma by Tianhao Tong, Wenhui Gao, Huiying Jian, Renyi Yang, Jingting Zhang, Kexiong Li, Puhua Zeng

“…Future research should prioritize elucidating the functional implications of exosome-mediated signaling pathways, developing reproducible methodologies, and conducting large-scale clinical trials. …”
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Ghrelin-induced neuronal NPY promotes brain metastasis in lung cancer patients with low BMI by Abhishek Tyagi, Shih-Ying Wu, Jee-Won Kim, Ravindra Pramod Deshpande, Kerui Wu, Eleanor C. Smith, Giuseppe L. Banna, Kounosuke Watabe

“…These findings provide a strong rationale for developing targeted interventions to treat or prevent brain metastasis in lung cancer patients with low BMI.…”
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Nanoparticle-mediated targeting of PGC-1α reveals critical metabolic pathways in bladder cancer metastasis by Zhenghua Liu, Peng Xin, Weiwei Wu, Mingyue Jin, Yang Du, Yuanjun Jiang, Tao Liu, Hao Zhang

“…These findings highlight PGC-1α as a key regulator of metabolic reprogramming in metastatic bladder cancer and suggest that its inhibition could serve as a promising therapeutic strategy. …”
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Metabolomics’ Change Under β-Cypermethrin Stress and Detoxification Role of <i>CYP5011A1</i> in <i>Tetrahymena thermophila</i> by Wenyong Zhang, Wenliang Lei, Tao Bo, Jing Xu, Wei Wang

“…Conclusions: These findings confirmed that <i>T. thermophila</i> develops β-CYP tolerance by carbohydrate metabolism reprogramming and Cyp5011A1 improves cellular adaptations by influencing amino acid metabolisms. …”
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Fatty acid synthase inhibitor cerulenin hinders liver cancer stem cell properties through FASN/APP axis as novel therapeutic strategies by Liang-Yun Chen, Dao-Sian Wu, Yao-An Shen

“…Therefore, to address the therapeutic conundrum, this study focused on rewinding metabolic reprogramming of CSCs as a novel therapeutic strategy. …”
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Recent advances in dermal fibroblast senescence and skin aging: unraveling mechanisms and pioneering therapeutic strategies by Li Nan, Pengchao Guo, Wang Hui, Fang Xia, Chenggang Yi

“…This review delves into the molecular and cellular dynamics of dermal fibroblast aging, emphasizing their relevance for developing novel anti-aging interventions.…”
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Different fibroblast subtypes propel spatially defined ileal inflammation through TNFR1 signalling in murine ileitis by Lida Iliopoulou, Christos Tzaferis, Alejandro Prados, Fani Roumelioti, Vasiliki Koliaraki, George Kollias

“…The Tnf ΔΑRE mice, which spontaneously develop CD-like ileitis due to TNF overexpression, represent a faithful model of the human disease. …”
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Epithelial-mesenchymal transition in colorectal cancer metastasis and progression: molecular mechanisms and therapeutic strategies by Fangfang Nie, Xue Sun, Jizhuo Sun, Jingdong Zhang, Yuanhe Wang

“…Beyond metastasis, EMT facilitates cancer cells’ adaptation to diverse microenvironments, gain of stem cell-like characteristics, metabolic reprogramming, and evasion of therapeutic interventions. …”
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In vivo structure profiling reveals human cytosolic and mitochondrial tRNA structurome and interactome in response to stress by Noah Peña, Yichen Hou, Christopher P. Watkins, Sihao Huang, Wen Zhang, Christopher D. Katanski, Tao Pan

“…We also identify cytosolic and mitochondrial tRNA structure and interaction changes upon arsenite treatment, a type of oxidative stress that induces translational reprogramming, which is consistent with global translation repression in both compartments. …”
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Serum metabolite levels identify incipient metastatic progression of rectal cancer by Kine M. Bakke, Paula A. Bousquet, Sebastian Meltzer, Tonje Bjørnetrø, Frode Rise, Alistair L. Wilkins, Kathrine Røe Redalen, Anne Hansen Ree

“…Abstract Background The cellular metabolism undergoes reprogramming during the metastatic process. We hypothesised that serum metabolites at the time of primary tumour diagnosis might identify rectal cancer patients prone to metastatic progression. …”
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Harnessing EVs-ncRNA for Lung Cancer: From Oncogenic Pathways to Novel Diagnostic and Therapeutic Strategies by Shi Y, Chen H, Li W, An S, Li L, Gao H

“…This synthesis provides a molecular foundation and translational framework for developing innovative diagnostic and therapeutic strategies in lung cancer management.Keywords: EVs, exosome, ncRNA, lung cancer, NSCLC, TME…”
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Pooled PPIseq: Screening the SARS-CoV-2 and human interface with a scalable multiplexed protein-protein interaction assay platform. by Darach Miller, Adam Dziulko, Sasha Levy

“…Protein-Protein Interactions (PPIs) are a key interface between virus and host, and these interactions are important to both viral reprogramming of the host and to host restriction of viral infection. …”
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Computational modeling of the hematopoietic erythroid-myeloid switch reveals insights into cooperativity, priming, and irreversibility. by Vijay Chickarmane, Tariq Enver, Carsten Peterson

“…Understanding the underlying molecular circuitry in terms of how it governs both a primed state and, at the other extreme, a committed state is of relevance not only to hematopoiesis but also to developmental systems in general. We develop a computational model for the hematopoietic erythroid-myeloid lineage decision, which is determined by a genetic switch involving the genes PU.1 and GATA-1. …”
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Learning and cognition in highspeed decision making by Martin Krause, Wolfram Schulze, Stefan Schuster

“…We discovered that, surprisingly, adult fish could reprogram their highspeed decision to the new rule. …”
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