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Construction and Influence of Induced Pluripotent Stem Cells on Early Embryo Development in Black Bone Sheep
Published 2025-04-01“…When used in conjunction with somatic cell nuclear transfer experiments, it can precisely and effectively reveal the intrinsic mechanisms of early biological development. This study successfully reprogrammed black-boned sheep fibroblasts (SFs) into induced pluripotent stem cells (iPSCs) using the piggyBac+TET-on transposon system and investigated their impact on early embryonic development. …”
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Predictive genetic circuit design for phenotype reprogramming in plants
Published 2025-01-01“…A predictive model is developed to predict the designed circuits’ behavior accurately. …”
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Modeling the Effect of Cannabinoid Exposure During Human Neurodevelopment Using Bidimensional and Tridimensional Cultures
Published 2025-01-01Subjects: Get full text
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Translational reprogramming under heat stress: a plant’s perspective
Published 2025-07-01“…To maximize fitness and chances of survival, plants continuously adjust their growth, development and physiology to their temperature environment. …”
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Metabolic reprogramming in polycystic kidney disease and other renal ciliopathies
Published 2025-04-01“…The past decade has seen a surge of studies highlighting metabolic reprogramming as a major feature of PKD, with a distinct involvement of mitochondrial dysfunction. …”
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Targeting metabolic reprogramming to overcome immune tolerance in melanoma immunotherapy
Published 2025-06-01“…This review also examines how metabolic reprogramming supports tumor proliferation and immune evasion, it highlights the impact of extracellular acidification and angiogenic processes on resistance development. …”
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Unlocking the secrets of glucose metabolism reprogramming: the role in pulmonary diseases
Published 2025-08-01“…Metabolic reprogramming is the process by which cells adapt to different patterns of energy metabolism in response to the demands of the microenvironment for energy and biological macromolecules. …”
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Lactate and lactylation: emerging roles in autoimmune diseases and metabolic reprogramming
Published 2025-06-01“…While current treatments can somewhat control disease progression, their long-term effectiveness remains limited, necessitating the development of more effective therapeutic approaches. …”
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Genetic modifiers of chromatin acetylation antagonize the reprogramming of epi-polymorphisms.
Published 2012-09-01“…Our observations provide a basis for the development of population epigenetics.…”
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Two factor reprogramming of human neural stem cells into pluripotency.
Published 2009-09-01“…<h4>Background</h4>Reprogramming human somatic cells to pluripotency represents a valuable resource for the development of in vitro based models for human disease and holds tremendous potential for deriving patient-specific pluripotent stem cells. …”
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Lipid metabolic reprogramming in colorectal cancer: mechanisms and therapeutic strategies
Published 2025-07-01“…Moreover, the lipid metabolic reprogramming of tumor cells is closely related to various cells within the TME, and these interactions promote, to some extent, the remodeling of the tumor microenvironment, further driving tumor development. …”
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Metabolic reprogramming and immunosenescence in colorectal cancer: mechanisms and therapeutic implications
Published 2025-08-01“…In recent years, metabolic reprogramming and immunosenescence have received extensive attention as key mechanisms for tumorigenesis, development and treatment resistance. …”
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Interactions between the metabolic reprogramming of liver cancer and tumor microenvironment
Published 2025-02-01“…Metabolic reprogramming is one of the major biological features of malignant tumors, playing a crucial role in the initiation and progression of cancer. …”
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Nanotechnology-Based Cardiac Targeting and Direct Cardiac Reprogramming: The Betrothed
Published 2017-01-01“…First developed for cancer treatment, nanotechnology-based approaches have opened new perspectives in many fields of medical research, including cardiovascular research. …”
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Comparative analysis of mouse strains for in vivo induction of reprogramming factors
Published 2025-07-01“…In addition, we develop reprogrammable mouse strains by avoiding OSKM expression in specific organs or implementing expression approaches within specific cells, thereby offering safer strategies to induce in vivo reprogramming. …”
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Optimization of Adversarial Reprogramming for Transfer Learning on Closed Box Models
Published 2025-01-01“…We use the Black Box Adversarial Reprogramming (BAR) algorithm to process target domain data in a source domain model through adversarial reprogramming. …”
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Direct fibroblast reprogramming: an emerging strategy for treating organic fibrosis
Published 2025-02-01“…Understanding the link between reprogramming and fibrosis could help develop effective strategies to treat damaged tissue with a potential risk of fibrosis. …”
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Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer
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Promoting practices of sufficiency: reprogramming resource-intensive material arrangements
Published 2024-11-01“…This paper explores theoretically the possible pathways for sufficiency-based everyday practices within existing, slightly modified materialities. It develops the concept of ‘reprogramming’, i.e. to promote sufficiency through performing practices in different ways within existing or slightly modified material arrangements, and it explores how changes in institutional arrangements further can promote such resource-light practices. …”
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