The Overlapping Biology of Sepsis and Cancer and Therapeutic Implications by Amit Kumar Tripathi, Yogesh Srivastava

“…Both conditions exhibit metabolic reprogramming, such as the Warburg effect in cancer and glycolysis-driven immune cell activation in sepsis, which fuels disease progression and complicates treatment. …”
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TRIM21: a multifaceted regulator in cancer by Aizhuo Li, Jiannan Wang, Yi Qu

“…By specifically recognizing and ubiquitinating various substrate proteins, it plays a pivotal regulatory role in tumorigenesis and development. Moreover, TRIM21 has been found to play a multi-faceted role in cellular autophagy, metabolic reprogramming, immune escape, tumor proliferation, metastasis and resistance to cell death by regulating the stability and function of key proteins. …”
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Nanomedicines Targeting Metabolic Pathways in the Tumor Microenvironment: Future Perspectives and the Role of AI by Shuai Fan, Wenyu Wang, Wenbo Che, Yicheng Xu, Chuan Jin, Lei Dong, Qin Xia

“…<b>Methods:</b> We have conducted a detailed review of key papers from databases, such as ScienceDirect, Scopus, Wiley, Web of Science, and PubMed, focusing on tumor metabolic reprogramming, the mechanisms of action of nanomedicines, the development of nanomedicines targeting tumor metabolism, and the application of AI in empowering nanomedicines. …”
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A Review of Advances in Mitochondrial Research in Cancer by Zhiru Li BS, Wu Zhang BS, Shaowei Guo MS, Guoyan Qi MD, Jiandi Huang BS, Jin Gao MS, Jing Zhao MD, Lin Kang MS, Qingxia Li PhD, MD

“…Background Abnormalities in mitochondrial structure or function are closely related to the development of malignant tumors. Mitochondrial metabolic reprogramming provides precursor substances and energy for the vital activities of tumor cells, so that cancer cells can rapidly adapt to the unfavorable environment of hypoxia and nutrient deficiency. …”
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Neural differentiation in perspective: mitochondria as early programmers by Ramin M. Farahani, Ramin M. Farahani

“…Neural differentiation during development of the nervous system has been extensively studied for decades. …”
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Lactylation in tumor: mechanisms and therapeutic potentials by Dandan Wang, Hao Rong, Ke Ma, Jun Peng

“…Lactate, a central product of glucose metabolism, plays a vital role in energy supply and signal transduction, and it also participates in gene transcription regulation through lactylation. Metabolic reprogramming is a key feature of tumor cells and highlights the important role of lactylation in cancer development. …”
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Lipid metabolism in multiple myeloma: pathogenesis, therapeutic opportunities, and future directions by Huiquan Wang, Jiafeng Zhang, Hefei Ren, Lei Chen, Jigang Ren, Chang Liu, Hongkun Wu, Lin Zhou

“…In this review, we will discuss the alterations in lipid metabolism during the development of MM, and their reciprocal interactions with the tumor microenvironment.…”
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Advances in the regulation of macrophage polarization by the tumor microenvironment by Minzhi Peng, Yuan Zhu, Yi Hu, Jianping Wen, Weiguo Huang

“…Moreover, the metabolic reprogramming of tumorassociated macrophage (TAM) is a core mechanism for their functional shift, and intervening in metabolic pathways holds promise for reprogramming TAMs to inhibit tumor progression (Jin et al. in Nat Cancer 6:239–252, 2025). …”
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Knockout of the sulfide: quinone oxidoreductase SQR reduces growth of HCT116 tumor xenograft by Ting Lu, Qingda Wang, Yuping Xin, Xiaohua Wu, Yang Wang, Yongzhen Xia, Luying Xun, Huaiwei Liu

“…These insights lay a foundation for the development of SQR-targeted therapies for CRC.…”
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SLC25A35 enhances fatty acid oxidation and mitochondrial biogenesis to promote the carcinogenesis and progression of hepatocellular carcinoma by upregulating PGC-1α by Heng-Chao Yu, Lu Bai, Liang Jin, Yu-Jia Zhang, Zi-Han Xi, De-Sheng Wang

“…However, the role of SLC25A35 in mitochondrial metabolism reprogramming, development and progression in human cancers remains unclear. …”
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On Application-Customized Common Platform for Wireless Vehicular Sensor Networks by Hongchao Wang, Zhen Han, Dong Yang

“…Developing, deploying, or reprogramming an application in a short time and at a low cost is necessary in wireless vehicular sensor and vehicular ad hoc networks. …”
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Tumor-Associated Macrophages: Polarization, Immunoregulation, and Immunotherapy by Abdullah Farhan Saeed

“…Tumor-associated macrophages’ (TAMs) origin, polarization, and dynamic interaction in the tumor microenvironment (TME) influence cancer development. They are essential for homeostasis, monitoring, and immune protection. …”
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Research progress of zebrafish heart regeneration models by ZHANG Weijia, LIANG Jinxiu, HAN Peidong

“…In addition, we also explored the essential mechanisms underlying heart regeneration, including the spatiotemporal activation of multiple signaling pathways in different cell types, epigenetic reprogramming, coronary revascularization, activation of key development-related transcription factors, and the disassembly and reassembly of cardiomyocyte sarcomeric structure. …”
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Schwann cells in regeneration and cancer: an epithelial–mesenchymal transition perspective by Francisco Gracia, Berta Sanchez-Laorden, Jose A. Gomez-Sanchez

“…In various injury contexts, SCs undergo a reprogramming process that generates specialized cells to promote tissue regeneration and repair. …”
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Exploring Stressors: Impact on Cellular Organelles and Implications for Cellular Functions by Zoofa Zayani, Arash Matinahmadi, Alireza Tavakolpournegari, Seyed Hesamoddin Bidooki

“…A comprehensive understanding of the mechanisms by which organelles respond to stress can offer valuable insights into the development of therapeutic strategies aimed at mitigating cellular damage.…”
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Gastric cancer adapts high lipid microenvironment via suppressing PPARG-FABP1 axis after arriving in the lymph node by Yinan Liu, Liang Tang, Baifu Peng, Shaoji Zhao, Ziling Shao, Kaiyu Sun, Jinning Ye, Wei Chen, Jianbo Xu

“…Therefore, understanding the mechanism underlying metabolic reprogramming in lymph node (LN) metastasis is crucial for the development of targeted therapies for advanced gastric cancer. …”
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DNA methylation mechanisms in the maturing and ageing oocyte by Carla Caniçais, Sara Vasconcelos, Fátima Santos, Sofia Dória, C. Joana Marques

“…Here we highlight epigenetic reprogramming events occurring during oocyte development and ageing, focusing on the establishment of gamete-specific epigenetic marks, including DNA modifications at imprinted regions, and age-related epigenetic changes. …”
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DualNetM: an adaptive dual network framework for inferring functional-oriented markers by Bingjie Dai, Hanshuang Li, Peizhuo Wang, Pengwei Hu, Jixiang Xing, Yanan Hu, Qilemuge Xi, Yongchun Zuo

“…Additionally, DualNetM identified stage-specific functional markers and clarified their specific roles in mouse embryonic fibroblast reprogramming. DualNetM’s marker inference function demonstrated stronger biological relevance during primed reprogramming. …”
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Reconfigurable Soft Actuators Constructed via Layer‐by‐layer Assembly by Qing Chen, Loghman Jamilpanah, Tina Künniger, Roman Furrer, Qun Song, Kai Zhang, Andrei Chumakov, Constantin Harder, Yusuf Bulut, Peter Müller‐Buschbaum, Stephan V. Roth, Artur Braun

“…Abstract Stimuli‐responsive actuators are candidates for the development of soft robots due to their shape deformation and environmental adaptation capabilities. …”
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The role and research progress of serine metabolism in tumor cells by Hanning Lyu, Shuchang Bao, Lingyun Cai, Mengke Wang, Yuxin Liu, Yang Sun, Xiaoyang Hu

“…This paper reviews serine metabolic pathways and their roles in tumor development. It summarizes the influencing factors of serine metabolism. …”
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