Showing 21 - 40 results of 1,014 for search 'development reprogramming', query time: 0.09s Refine Results
  1. 21

    Direct Cardiac Reprogramming: Progress and Promise by James L. Engel, Reza Ardehali

    Published 2018-01-01
    “…Finally, we discuss the development of safer reprogramming approaches for future clinical application.…”
    Get full text
    Article
  2. 22

    Trajectories of macrophage ontogeny and reprogramming in cancer by Florent Duval, Joao Lourenco, Mehdi Hicham, Gaël Boivin, Alan Guichard, Celine Wyser-Rmili, Nadine Fournier, Nahal Mansouri, Michele De Palma

    Published 2025-05-01
    “…Dicer1 inactivation interfered with this trajectory and stalled TAMs at an intermediate state, impeding immunosuppressive and M2-like TAM development. This reprogramming translated into enhanced response to antiangiogenic immunotherapy in an orthotopic lung cancer model. …”
    Get full text
    Article
  3. 23

    Advances in the Study of Metabolic Reprogramming in Gastric Cancer by Yu Rong, Yuanyin Teng, Xiaoying Zhou

    Published 2025-05-01
    “…Methods Recent research has demonstrated that metabolic reprogramming—including alterations in glucose, lipid, and amino‐acid metabolism—plays a critical role in both the development and progression of this disease. …”
    Get full text
    Article
  4. 24

    Advances in MicroRNA-Mediated Reprogramming Technology by Chih-Hao Kuo, Shao-Yao Ying

    Published 2012-01-01
    “…Several approaches for ESC-specific miRNA-mediated reprogramming have been developed using cancer and somatic cells to generate ESC-like cells with similarity to iPSCs and/or hESCs. …”
    Get full text
    Article
  5. 25

    Post-translational modifications and the reprogramming of tumor metabolism by Yuqing Hu, Wenxia Xu, Lin Chen

    Published 2025-05-01
    “…Abstract Metabolic reprogramming occurs alongside tumor development. As cancers advance from precancerous lesions to locally invasive tumors and then to metastatic tumors, metabolic patterns exhibit distinct changes, including mutations in metabolic enzymes and modifications in the activity of metabolic regulatory proteins. …”
    Get full text
    Article
  6. 26
  7. 27

    The role of macrophage metabolic reprogramming in myocardial infarction by ZOU Zicong, GU Muyang, CHENG Xiang

    Published 2024-11-01
    “…This review summarizes the phenomenon of metabolic reprogramming in macrophages after MI and its impact on the regulation of inflammation and tissue repair after MI, providing more perspectives and scientific evidence for the development of macrophage-targeted therapeutic strategies.…”
    Get full text
    Article
  8. 28

    Metabolic Reprogramming in Melanoma: An Epigenetic Point of View by Stefano Giuliani, Celeste Accetta, Simona di Martino, Claudia De Vitis, Elena Messina, Edoardo Pescarmona, Maurizio Fanciulli, Gennaro Ciliberto, Rita Mancini, Italia Falcone

    Published 2025-06-01
    “…Metabolic reprogramming and epigenetic alterations are fundamental hallmarks of cancer cells, contributing to adaptation, progression, and resistance. …”
    Get full text
    Article
  9. 29

    Somatic cell reprogramming for Parkinson's disease treatment by Xiaozhuo Li, Kevin Fang, Fengping Wang

    Published 2025-03-01
    “…In recent years, novel therapeutic strategies have been developed, such as cell reprogramming, trying to generate more DA in PD treatment. …”
    Get full text
    Article
  10. 30
  11. 31

    CRISPR/Cas9-based genetic screen of SCNT-reprogramming resistant genes identifies critical genes for male germ cell development in mice by Most Sumona Akter, Masashi Hada, Daiki Shikata, Gen Watanabe, Atsuo Ogura, Shogo Matoba

    Published 2021-07-01
    “…We have previously identified somatic cell nuclear transfer-reprogramming resistant genes (SRRGs) that are highly enriched for genes essential for spermatogenesis, although many of them remain uncharacterized in knockout (KO) mice. …”
    Get full text
    Article
  12. 32

    Epigenetic reprogramming in mouse and human primordial germ cells by Sun-Min Lee, M. Azim Surani

    Published 2024-12-01
    “…Recent findings related to these processes provide a comprehensive overview of germline epigenetic reprogramming and its importance in mouse and human PGC development. …”
    Get full text
    Article
  13. 33

    Metabolic reprogramming in lung cancer and its clinical implication by Qingqiu Huang, Lisha Fan, Mingjing Gong, Juntong Ren, Chen Chen, Shenglong Xie

    Published 2024-12-01
    “…This article focuses on metabolic reprogramming of lung cancer cells, a process to adapt to energy demands and biosynthetic needs, supporting the proliferation and development of tumor cells. …”
    Get full text
    Article
  14. 34
  15. 35

    Hypoxia-driven angiogenesis and metabolic reprogramming in vascular tumors by Lu Liu, Lu Liu, Lu Liu, Lu Liu, Lu Liu, Jiayun Yu, Yang Liu, Yang Liu, Yang Liu, Yang Liu, Yang Liu, Liang Xie, Liang Xie, Liang Xie, Liang Xie, Liang Xie, Fan Hu, Fan Hu, Hanmin Liu, Hanmin Liu, Hanmin Liu, Hanmin Liu, Hanmin Liu, Hanmin Liu

    Published 2025-05-01
    “…This review discusses the molecular mechanisms by which hypoxia regulates angiogenesis and metabolic reprogramming in vascular tumors, highlighting the intricate link between these processes, and explores potential therapeutic strategies to target these pathways in order to develop effective treatment strategies for patients.…”
    Get full text
    Article
  16. 36

    Macrophage polarization and metabolic reprogramming in abdominal aortic aneurysm by Ningxin Hou, Hongmin Zhou, Jun Li, Xiaoxing Xiong, Hongping Deng, Sizheng Xiong

    Published 2024-11-01
    “…The limitation of the current management is that most patients can only be followed up until the AAA diameter increases to a threshold, and surgical intervention is recommended. The development of preventive and curative drugs for AAA is urgently needed. …”
    Get full text
    Article
  17. 37
  18. 38

    PKM2-mediated metabolic reprogramming of microglia in neuroinflammation by Qi Zhang, Sha-Sha Wang, Zhao Zhang, Shi-Feng Chu

    Published 2025-04-01
    “…Abstract Microglia, the resident immune cells of the central nervous system, undergo metabolic reprogramming during neuroinflammation, playing a crucial role in the pathogenesis of neurological disorders such as Parkinson’s disease. …”
    Get full text
    Article
  19. 39

    Cellular Reprogramming Using Defined Factors and MicroRNAs by Takanori Eguchi, Takuo Kuboki

    Published 2016-01-01
    “…Induced pluripotent stem (iPS) cells have been recently developed using defined reprogramming factors such as Nanog, Klf5, Oct3/4 (Pou5f1), Sox2, and Myc. …”
    Get full text
    Article
  20. 40

    Metabolic reprogramming of macrophages in the context of type 2 diabetes by Leonel Witcoski Junior, Jordana Dinorá de Lima, Amanda Girardi Somensi, Lucas Brito de Souza Santos, Giulia Leonel Paschoal, Thalita Suemy Uada, Thais Sibioni Berti Bastos, André Guilherme Portela de Paula, Rebeca Bosso Dos Santos Luz, Andressa Pacheco Czaikovski, Mariana Rodrigues Davanso, Tarcio Teodoro Braga

    Published 2024-10-01
    “…Macrophages play a crucial role in this context, influencing both the development and progression of insulin resistance. These innate immune cells respond to inflammatory stimuli and reprogram their metabolism, directly impacting the pathophysiology of T2D. …”
    Get full text
    Article