Methylome profile of medaka eggs and sperm by Xuegeng Wang, Ramji K. Bhandari

“…Following the epigenetic reprogramming of the embryo, core epigenetic information present in the sperm and eggs is transmitted to offspring somatic cells prior to the blastula stage, which specifically influences gene expression in the cells. …”
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Mechanistic insights into promotion of non-small cell lung cancer by BAG5 using integrative multi-omics approaches by Jing-Shan Huang, Jing-Shan Huang, Jing-Shan Huang, Jia-Mei Wang, Ye Yuan, Ting Zhang, Bai-Qiang Li, Fu-Ying Zhao, Liang Hao, Zhan-Wu Yu, Hua-Qin Wang

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Reprogrammer la smart city : le quotidien des habitants de Songdo en Corée du Sud by Suzanne Peyrard

“…However, these technologies are sometimes repurposed or even reprogrammed by "expert" residents, highlighting a form of appropriation that diverges from the designers’ original intentions.…”
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Sepsis therapies: learning from 30 years of failure of translational research to propose new leads by Jean‐Marc Cavaillon, Mervyn Singer, Tomasz Skirecki

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Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis by Li Lu, Jiewen Liao, Chao Xu, Yuan Xiong, Juan Zhou, Guangji Wang, Ze Lin, Kangkang Zha, Chuanlu Lin, Ruiyin Zeng, Guandong Dai, Qian Feng, Bobin Mi, Guohui Liu

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Aerobic exercise preconditioning suppresses subcutaneous tumorigenesis via PI3K/AKT-driven metabolic epigenetic reprogramming and immune microenvironment remodeling by Xue Zhang, Yixue Xia, Lingbing Zheng, Lu Cao, Zhengtang Qi, Shuzhe Ding

“…It has been widely recognized that aerobic exercise inhibits tumors, and aerobic glycolysis is closely related to tumor development. Whether exercise preconditioning inhibits subcutaneous tumor growth remains unclear. …”
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Targeting HVEM-GPT2 axis: a novel approach to T cell activation and metabolic reprogramming in non-small cell lung cancer therapy by Yuanshan Yao, Chunji Chen, Bin Li, Wen Gao

“…Abstract Background The modulation of tumor microenvironments through immune checkpoint pathways is pivotal for the development of effective cancer immunotherapies. This study aims to explore the role of HVEM in non-small cell lung cancer (NSCLC) microenvironment. …”
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The Macrophage Activator GcMAF-RF Enhances the Antitumor Effect of Karanahan Technology through Induction of M2–M1 Macrophage Reprogramming by Vera S. Ruzanova, Svetlana S. Kirikovich, Evgeniy V. Levites, Anastasia S. Proskurina, Evgeniya V. Dolgova, Genrikh S. Ritter, Yaroslav R. Efremov, Tatyana D. Dubatolova, Alexander V. Sysoev, Danil I. Koleno, Alexandr A. Ostanin, Elena R. Chernykh, Sergey S. Bogachev

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A Systems Hypothesis of Lipopolysaccharide-Induced Vitamin Transport Suppression and Metabolic Reprogramming in Autism Spectrum Disorders: An Open Call for Validation and Therapeut... by Albion Dervishi

“…<b>Background:</b> Autism spectrum disorder (ASD) is increasingly linked to systemic metabolic dysfunction, potentially influenced by gut–brain axis dysregulation, but the underlying mechanisms remain unclear. <b>Methods:</b> We developed Personalized Metabolic Margin Mapping (PM³), a computational systems biology framework, to analyze RNA-seq data from 12 ASD and 12 control postmortem brain samples. …”
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Syndecan-4 promotes gastric cancer progression through activating TGF-β1 induced lipid reprogramming and contributes positive loop circuits by Guangjie Liu, Ru Jia, Heng Deng, Xiaoshan Wang

“…However, the regulatory mechanism of SDC4 in lipid reprogramming has not yet been elucidated. Therefore, it is important to investigate underlying mechanisms and develop novel therapeutic targets for gastric cancer (GC). …”
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Differential Transcriptome Reprogramming Induced by the Soybean Cyst Nematode Type 0 and Type 1.2.5.7 During Resistant and Susceptible Interactions by Mst Shamira Sultana, Daniel Niyikiza, Tracy E. Hawk, Nicole Coffey, Valéria Lopes-Caitar, Alexander C. Pfotenhauer, Hana El-Messidi, Chris Wyman, Vince Pantalone, Tarek Hewezi

“…However, the impacts of various SCN Hg types on host transcriptome reprogramming remain largely unknown. Here, we developed and used two recombinant inbred lines (RIL; RIL-72 and RIL-137) to profile transcriptome reprogramming in the infection sites during the resistant and susceptible interactions with SCN Hg Type 1.2.5.7 and Type 0. …”
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Novel cancer stem cell-targeted retinoid ZSH-512 impedes colorectal cancer progress via KDM3A-mediated epigenetic reprogramming by Suyao Li, Wenrui Zhao, Quanlin An, Lei Wang, Mengxuan Zhu, Junjie Ni, Xuan Huang, Yudong Jiang, Min Li, Jiayun Hou, Yiyi Yu, Shan Yu, Lai Wei, Heng Jiao, Tianshu Liu, Xin Cao

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Acetylated Dendrobium huoshanense polysaccharide: a novel inducer of apoptosis in colon cancer cells via Fas–FasL pathway activation and metabolic reprogramming by Liang Yao, Liang Yao, Liang Yao, Chen Gu, Chen Gu, Chen Gu, Ruipeng Ge, Ruipeng Ge, Ruipeng Ge, Xiaoqian Zhang, Xiaoqian Zhang, Xinqian Meng, Xinqian Meng, Lei Wang, Lei Wang, Lei Wang, Lei Wang, Daiyin Peng, Daiyin Peng, Daiyin Peng, Daiyin Peng, Guozhuan Li, Guozhuan Li

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CRSP8-driven fatty acid metabolism reprogramming enhances hepatocellular carcinoma progression by inhibiting RAN-mediated PPARα nucleus-cytoplasm shuttling by Yuxi Lin, Zhixing Liang, Zhiyan Weng, Xiaofang Liu, Feng Zhang, Yutian Chong

“…Abstract Background In-depth exploration into the dysregulation of lipid metabolism in hepatocellular carcinoma (HCC) has contributed to the development of advanced antitumor strategies. CRSP8 is a critical component of mediator multiprotein complex involved in transcriptional recruiting. …”
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Interleukin-16 enhances anti-tumor immune responses by establishing a Th1 cell-macrophage crosstalk through reprogramming glutamine metabolism in mice by Zhenzhen Wen, Tong Liu, Xutao Xu, Nandini Acharya, Zhida Shen, Yunkun Lu, Junjie Xu, Ke Guo, Shuying Shen, Yuening Zhao, Pinli Wang, Shumin Li, Weiyu Chen, Hui Li, Yimin Ding, Min Shang, Hongshan Guo, Yu Hou, Bijun Cui, Manlu Shen, Youling Huang, Ting Pan, Wang Qingqing, Qian Cao, Kai Wang, Peng Xiao

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Role of Tumor Microenvironment in Prostate Cancer Immunometabolism by Yutao Wang, Yiming Chen, Jianfeng Wang

“…This review examines the dynamic interactions between tumor cells and immune cells within the prostate cancer TME, focusing on how metabolic reprogramming of both tumor and immune cells drives immunosuppression. …”
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Partial Cell Fate Transitions to Promote Cardiac Regeneration by Jianchang Yang

“…Heart disease, including myocardial infarction (MI), remains a leading cause of morbidity and mortality worldwide, necessitating the development of more effective regenerative therapies. …”
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Glutamine’s double-edged sword: fueling tumor growth and offering therapeutic hope by Liguang Fang, Dandan Gao, Zuomin Jiang, Guoliang Li, Ming Li, Ming Li

“…Therefore, further exploration of glutamine metabolism in tumors is essential for understanding the pathogenesis of cancer and for developing new metabolically targeted therapies. We systematically review the latest research on the reprogramming of glutamine metabolism and its role of tumor growth, spread, and immune system regulation. …”
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Targeting KRAS: from metabolic regulation to cancer treatment by Yanyan Shi, Huiling Zheng, Tianzhen Wang, Shengpu Zhou, Shiqing Zhao, Mo Li, Baoshan Cao

“…Here, we review the metabolic reprogramming of glucose, glutamine, and lipids regulated by oncogenic KRAS, with an emphasis on recent insights into the relationship between changes in metabolic mechanisms driven by KRAS mutant and related advances in targeted therapy. …”
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Analyzing research trends in glioblastoma metabolism: a bibliometric review by Jiaxin Dai, Jiaxin Dai, Siyun Song, Pengyu Chen, Pengyu Chen, Qixuan Huang, Qixuan Huang, Hubin Duan, Hubin Duan

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