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1861
Development of interactive learning media based on socio-scientific issues using Smart Apps Creator in the role of viruses for tenth graders
Published 2025-07-01“…The research design used Research and Development (R&D), approach ADDIE development model. …”
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1862
Development of the composition and research of the equivalence of suppositories with diclofenac sodium by in vitro method using “Dissolution” test for lipophilic solid dosage forms...
Published 2019-04-01“…Materials and methods: The development of the suppository composition was carried out with the use of the substance of diclofenac sodium and the excipient of solid fat of various grades. …”
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1863
Psychological and Pedagogical Foundations of Teacher Training for Development of Primary School Student’s Initial Representations (Based on The Course Material Natural Science)
Published 2022-12-01“…In 2021, a working group of the Moscow State University of Psychology and Education developed a technique for developing student’s initial representations to scientific concepts based on the material of mathematics and natural sciences in primary school. …”
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1864
Association between positive youth development and family functioning in the Chinese context: a four-wave longitudinal survey in mainland China
Published 2024-12-01“…IntroductionThere is a notable scarcity of research examining the developmental trajectories of positive youth development (PYD) attributes among Chinese preadolescents and adolescents and the predictive effect of family functioning on these trajectories over time.MethodsUsing four waves of data, this longitudinal study investigated preadolescents and adolescents in China in January 2020 (T1), June 2020 (T2), June 2021 (T3), and June 2022 (T4). …”
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1865
ARTICLE RETRACTED DUE TO PLAGIARISM BY THE AUTHOR Development of motor skills of children aged 9-10 years with visual analyzer impairment
Published 2024-05-01“…Conclusion: The results obtained allow us to conclude that our proposed method of using general developmental exercises with objects as a means of developing coordination abilities in children 9-10 years old diagnosed with myopia is effective, which is achieved through regular use of exercises in physical education lessons, as well as by stabilizing the course of myopia during the school day. …”
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1866
Prognostic and Therapeutic Implications of Alamandine Receptor MrgD Expression in Clear Cell Renal Cell Carcinoma with Development of Metastatic Disease
Published 2025-03-01“…High MrgD expression in primary tumors was significantly associated with larger size, advanced stage, higher histological grade, and worse overall survival. Among 81 patients with metachronous metastases, high MrgD expression independently predicted shorter disease-free survival. …”
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1867
Epigenetic influence of long non-coding RNAs on the development of insulin resistance in metabolically associated fatty liver disease (part 2)
Published 2025-05-01“…The leading triggers that cause the development of IR in adipocytes are lipotoxicity and low-grade inflammation of adipose tissue. …”
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1868
Ultrasound-detected osteophytes predict the development of radiographic and clinical features of hand osteoarthritis in the same finger joints 5 years later
Published 2017-08-01“…Our aim was to explore whether ultrasound-detected osteophytes (in radiographically and clinically normal finger joints) predicted the development of radiographic and clinical hand OA 5 years later.Methods We included finger joints without radiographic OA (Kellgren-Lawrence grade (KLG)=0; n=301) or no clinical bony enlargements (n=717) at baseline and examined whether ultrasound-detected osteophytes predicted incident radiographic OA (KLG ≥1, osteophytes or joint space narrowing (JSN)) or incident clinical bony enlargement (dependent variables) in the same joints 5 years later. …”
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1869
Development and design validation of a novel network meta-analysis presentation tool for multiple outcomes: a qualitative descriptive study
Published 2022-06-01“…Objective The Grades of Recommendations, Assessment, Development and Evaluation working group recently developed an innovative approach to interpreting results from network meta-analyses (NMA) through minimally and partially contextualised methods; however, the optimal method for presenting results for multiple outcomes using this approach remains uncertain. …”
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1870
Outcomes associated with older patients who present or develop delirium in the emergency department: protocol for a systematic review and meta-analysis
Published 2025-05-01“…This systematic review aims to examine associations between older patients who present or develop delirium in the ED and adverse outcomes within the hospital and after discharge.Methods and analysis Searches will be conducted in MEDLINE, Embase, Web of Science, Cumulative Index to Nursing and Allied Health Literature, and the Cochrane Library. …”
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1871
Development and validation of a stability-indicating HPLC method for the simultaneous determination of anticoccidial drugs in veterinary formulations: greenness and whiteness asses...
Published 2025-02-01“…A Supelcosil C18 column was used as the stationary phase, and 0.05 M KH2PO4 and acetonitrile were mixed in a ratio of 80:20 (v/v) as the developing system with a flow rate of 2.0 mL min−1. …”
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1872
Ultrasound characteristics comparison and development of a predictive nomogram for intraductal papilloma and ductal carcinoma in situ: a retrospective cohort study
Published 2025-04-01“…IDP was classified into Grades 3, 4, and 5, whereas DCIS presented with a mass-like morphology. …”
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1873
A novel teaching model using a massive online open course for soft skills development in the veterinary medicine curriculum
Published 2025-04-01“…Likewise, the invested time (6.41, 5.09, and 4.19 h respectively) and the global participation 94.16%, as well as the conformity of the students with respect to the learning process with grades from 7.85 before the introduction of the pedagogical model to 8.59 after it.DiscussionInnovative methodologies centered on technology are valuable for developing soft skills as evidenced by the implementation of the MOOC “Learning How to Learn” within the context of Parasitic Diseases. …”
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1874
Development and validation of risk prediction models for acute kidney disease in gout patients: a retrospective study using machine learning
Published 2025-07-01“…SHAP visualizations revealed that the key predictors of AKI in gout patients were diuretics, serum sodium, and urate lowering; therapy agents, while predictors for AKD included age, diuretics, and AKI grade. SHAP force plots and LIME analyses provided individualized predictions. …”
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1875
Genetic polymorphisms of matrix metalloproteinase-9, tissue inhibitor of matrix metalloproteinase-1 and development of postoperative atrial fibrillation in elderly patients
Published 2018-11-01“…According to results of multivariate regression analysis the odds ratio of POAF development in patients with stable angina grade III was 1,8 (95% CI 0,5-75, p=0,4), NYHA III — 0,85 (95% CI 0,2-3,5, p=0,55), history of CAD more than 20 months — 1,8 (95% CI 1,2-8,1, p=0,03), LA diameter more than 39 mm — 4,2 (95% CI 1,6-9,5, p<0,0001), allele G MMP-9 A8202G — 2,6 (95% CI 1,2-75, p=0,03). …”
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1876
Development and evaluation of a school-based bullying prevention program (Bullying&You): study protocol for a cluster randomized trial
Published 2025-03-01“…Although school-based bullying prevention programs seem overall capable of reducing the frequency of bullying, the continuous development, improvement, and rigorous evaluation of bullying prevention programs with enhanced feasibility and efficacy is critical. …”
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1877
Development and Internal-External Validation Models for Cervical Cancer Overall Survival Prognosis: A SEER-Based Study and Chinese Data
Published 2025-07-01“…Univariate and multivariate Cox regression were used to construct a prognostic model based on the training set and develop a nomogram to predict the 3-year, 5-year, and 10-year OS of CC patients. …”
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1878
Integrated ultrasensitive metabolomics and single-cell transcriptomics identify crucial regulators of sheep oocyte maturation and early embryo development in vitro
Published 2025-07-01“…Introduction: Developmental competence of oocytes matured in vitro is limited due to a lack of complete understanding of metabolism and metabolic gene expression during oocyte maturation and embryo development. …”
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1879
Ex vivo lung perfusion-to-lung transplant rat survival model with reproducible development of acute lung injury and graft rejection
Published 2025-08-01“…F344-to-WKy EVLP-to-LTx developed significant histologic (as measured by acute lung injury score, ISHLT A and B grade rejection score) and radiologic (volume and mean Hounsfield units of aerated lung graft analyzed by computed tomography at day 7 after EVLP-to-LTx) changes in the lung allograft. …”
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1880