Evaluación de la fractura por fatiga del cigüeñal de un motor Diesel. // Evaluation of the crank shaft fatigue failure of a boat diesel engine. by R. A. Goytisolo Espinosa, J. G. Noa Águila, N. Arzola de la Peña, L. Castellanos González, H. Hernández Herrera, L. López Torres, A. Fernández Cañizares

“…<br />The crankshaft material investigation showed that it was steel grade 30. The calculations showed that the steel resistance<br />capacity is not enough to support the stresses produced in the crankshaft output elbow. …”
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Improving Artificial Intelligence–based Microbial Keratitis Screening Tools Constrained by Limited Data Using Synthetic Generation of Slit-Lamp Photos by Daniel Wang, BA, Bonnie Sklar, MD, James Tian, MD, Rami Gabriel, MD, Matthew Engelhard, MD, PhD, Ryan P. McNabb, PhD, Anthony N. Kuo, MD

“…Objective: We developed a novel slit-lamp photography (SLP) generative adversarial network (GAN) model using limited data to supplement and improve the performance of an artificial intelligence (AI)–based microbial keratitis (MK) screening model. …”
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Unraveling the significance of cuproptosis in hepatocellular carcinoma heterogeneity and tumor microenvironment through integrated single-cell sequencing and machine learning appro... by Wang Liu, Liangjing Xia, Yuan peng, Qiang Cao, Ke Xu, Huiyan Luo, Yongjun Peng, Yanping Zhang

“…The risk model stratified patients (validated in TCGA/GEO/ICGC), correlating with clinical grade, T-stage, survival (HR = 2.597, 95%CI 2.051–3.289, P < 0.05). …”
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IMMUNOTHERAPY IN ALL: MONOCLONAL ANTIBODIES AND BEYOND by Fatma Arıkan

“…In 2017, it received FDA approval after monotherapy with inotuzumab showed superiority over standard chemotherapy for relapsed/refractory CD22(+) B-ALL. The most common grade ≥3 side effects are hematologic and liver-related, including 11% VOD, which is mostly seen after sequential allo-HSCT. …”
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Conservation in action: Cost-effective UAVs and real-time detection of the globally threatened swamp deer (Rucervus duvaucelii) by Ravindra Nath Tripathi, Karan Agarwal, Vikas Tripathi, Ruchi Badola, Syed Ainul Hussain

“…This framework operates on a local server, synchronizing with consumer-grade UAVs at a rate of 32 frames per second (fps) with 320 pixel resolution using a frame sampling technique, notably without requiring a dedicated Graphical Processing Unit (GPU). …”
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Abstract 088: Treatment of a Ruptured AVM with Inflow Aneurysms: Mixed approach using coil and liquid embolization by Danah Bakir, Shashi Maryala, Casey Muehle

“…CT‐ angiogram demonstrated a prominent AVM with a well‐developed nidus situated to the left of midline about the posterior corpus callosum. …”
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Role and mechanism of a novel fusion gene RELCH-RET in driving malignant transformation of human bronchial epithelial cells: a preliminary study by ZHOU Xiaogang, ZHOU Xiaogang, HAO Xianglin, XIA Jiying

“…In the mouse xenograft tumor model, HBE cells stably expressing RELCH-RET developed significant tumor nodules (P<0.001), whereas the control groups (empty vector and wild-type RET) failed to exhibit detectable tumor growth. …”
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Factores psicosociales asociados con la alimentación saludable y la práctica de actividad física en escolares (Psychosocial factors associated with healthy eating and physical act... by María de los Angeles Fuentes Vega

“…Food security and physical activity (PA) provide benefits to the well-being of developing individuals that are reflected in physical, social and psychological aspects. …”
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Machine Learning Radiomics for Predicting Response to MR-Guided Radiotherapy in Unresectable Hepatocellular Carcinoma: A Multicenter Cohort Study by Su K, Liu X, Zeng YC, Xu J, Li H, Wang H, Du S, Wang H, Yue J, Yin Y, Li Z

“…No patient experienced Grade 3/4 adverse events. 1130 radiomics features were extracted from the GTV, of which 7 were included for further analysis. …”
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Hypertension and Elevated Pulse Pressure Responsive to Biomass Pollutants Exposures in Young Workers From the Democratic Republic of Congo: A Cross‐Sectional Analysis by Pierre Lofuta Olenga Vuvu, Malgorzata Klass, Nathalie Pauwen, Augustin Kipula, Silvia Perez Bogerd, Alain Van Muylem, Philippe Van de Borne, Gael Deboeck

“…Conclusions Charcoal producers appear to develop isolated systolic hypertension and HPP more, both indices of cardiovascular events in which occupational biomass particles seem to play an early significant role.…”
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Novel Classification of Peroneal Tendon Disease Reveals Cellular and Molecular Phenotypes of the Tenosvnovium by Julia Matthias MD, Michael A. David PhD, Sara E. Buckley DO, Daniel J. Ross MD, Nathaniel Zona BA, Michael A. Hewitt B.A., Joshua Metzl MD, Daniel K. Moon MD, MS, MBA, Courtney Grimsrud MD, Douglas J. Adams PhD, Michael Zuscik PhD, Kenneth Hunt MD

“…Furthermore, limited consensus exists on the classification of PTD, challenging accurate diagnosis and targeted therapeutic strategies. We aimed to develop a clinically meaningful classification system for PTD incorporating detailed analysis of molecular, cellular, and tissue changes of the tenosynovium surrounding the peroneal tendon. …”
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NFIA-dependent upregulation of SMC4 promotes metastasis and metabolic reprogramming in glioma by Guoyin Li, Guoyin Li, Yukui Zhao, Yubo He, Zhaoqiang Qian, Xiaoyan Li, Zewen Song, Zhiqiang Liu

“…A prognostic model (SRRS) was developed via LASSO regression and validated across cohorts.ResultsSMC4 was significantly overexpressed in glioma tissues, with higher expression correlating with advanced tumor grades and poorer patient survival (AUC &gt; 0.82). …”
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Colon cancer with extensive invasion of the abdominal wall treated with neoadjuvant chemotherapy and a free anterolateral thigh flap by Tsukasa Aritake, Akira Ouchi, Koji Komori, Takashi Kinoshita, Yusuke Sato, Ryota Nakamura, Keisuke Takanari, Hiroya Taniguchi, Kei Muro, Seiichi Kato, Tetsuya Abe, Seiji Ito, Yasuhiro Shimizu

“…After two courses of FOLFOXIRI (5-fluorouracil, leucovorin, oxaliplatin, and irinotecan), he developed an entero-cutaneous fistula due to tumor penetration and required emergency diverting ileostomy construction. …”
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Effects of diet type on the core fecal bacterial taxa and the dysbiosis index of healthy adult dogs by Patrícia M. Oba, Leah J. Roberts, Elizabeth L. Geary, Jan S. Suchodolski, Kelly S. Swanson, Kelly S. Swanson, Kelly S. Swanson

“…A qPCR-based dysbiosis index (DI) that assesses microbiome shifts was developed based on a subset of these taxa. Because most dogs consume kibble diets, published data on core bacteria and the DI were largely derived from dogs consuming that diet form. …”
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VF arrest secondary to immune checkpoint inhibitor (ICI)-associated myocarditis; improving patient outcomes by maintaining a high clinical suspicion for ICI toxicity by Victoria Floyd-Ellis

“…Discussion: Of all ICI toxicities, myocarditis is a rare complication, but carries a mortality rate as high as 50%.4 Its presentation varies widely, with only two other cases presenting with cardiac arrest being described in the literature.5,6 A systematic review reported presenting cardiac symptoms in only 47.1% of 238 ICI myocarditis cases. 12.6% reported non-specific symptoms, while 10.1% were asymptomatic. 30.3% presented with neuromuscular symptoms, a reminder that ICI myocarditis often develops as ‘triple-M syndrome’, concurrent with myositis and/or myasthenia gravis.7The systematic review echoes the importance of maintaining a low threshold for suspecting and investigating ICI myocarditis despite ambiguous symptoms.ESCO recognises that cancer therapy-related cardiovascular toxicity (CTR-CVT) risk is varied and provides suggestions for the level of attention such patients require depending upon the combination of likelihood (based on reported incidence) and degree (severity or grade) of adverse events. …”
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IgSF11–RAP1 signaling promotes cell migration and invasion of cutaneous melanoma by Yasuyuki Kobayashi, Kotaro Sugimoto, Minaka Ishibashi, Makoto Kobayashi, Shohei Igari, Shigeki Kitamura, Toshiyuki Yamamoto, Yuko Hashimoto, Hideki Chiba

“…The immunoglobulin superfamily 11 (IgSF11) functions as a cell adhesion protein and is overexpressed in several types of cancer, including high-grade glioma. However, it remains unknown whether and how IgSF11 stimulates malignant phenotypes. …”
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MANAGEMENT OF INDIVIDUAL WORK FOR THE SECOND YEAR STUDENTS BY INTRODUCTION THE MULTIMEDIA PRESENTATION IN „PROPAEDEUTIC OF PEDIATRIC THERAPEUTIC STOMATOLOGY” by O.V. Bazalytska, I.R. Kostiuk, G.M. Melnychuk, N.I. Shovkova, M.V. Bilyshchuk, O.M. Cherepiuk, O.E. Koshkin, R.P. Oliinyk, V.V. Starchenko

“…Thanks to this reports the future doctors develop responsibility and self-believe. We would like also admit that the foreign students, they usually do not like to work individually, are engaged in performance-presentation process. …”
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Effect of Intrathecal Bupivacaine Kept at Room Temperature versus Body Temperature on Shivering During Lower Limb Orthopaedic Surgery Under Spinal Anaesthesia: A Double-blind Rando... by Anil Kumar, Shuchi Nigam, Shipra Verma, Urvashi Yadav, Alankrita Acharya, Shailendra Kumar Patel

“…In group C, 40% of patients developed shivering of grade more than one, compared to 22.86% in group W. …”
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Analysis of standard vs dose-escalated stereotactic body radiation therapy in localized prostate cancer: a comparative evaluation of survival outcomes by Bichun Xu, Bichun Xu, Xianzhi Zhao, Xianzhi Zhao, Tingting Wei, Yiyin Liang, Weiwei Zhang, Liang Chen, Zuping Lian, Huojun Zhang

“…Patients with pre-existing health conditions were less likely to develop distant metastasis (p=0.047). Most patients tolerated SBRT with minimal toxicity, and no grade 3 or higher adverse events were observed.ConclusionEscalating the biologically effective dose above standard levels did not yield a significant improvement in tumor control or survival outcomes compared to conventional SBRT dosing for localized PCa. …”
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Mixed Reality Ultrasound-Guided Mini-ECIRS with Apple Vision Pro™ - First Case Report by Roberto Montoro Neto, Fabio C. Vicentini, Ricardo T.S. Ugino, Alexandre Danilovic, Giovanni S. Marchini, Fabio C.M. Torricelli, Carlos A. Batagello, Anderson B. Pellanda, Alexandre Silva, William C. Nahas, Eduardo Mazzucchi

“…Apple Vision Pro (AVP) is a spatial computing device developed by Apple that incorporates virtual reality (VR) for life-like simulations, realistic medical scenarios, interactive anatomical models, and augmented reality (AR) technologies (3). …”
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