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241
Profiling of gastric cancer cell-surface markers to achieve tumour–normal discrimination
Published 2020-12-01“…Promising candidates from this analysis were validated orthogonally using multispectral immunohistochemistry (mIHC) with automated quantitative analysis using the Vectra platform. mIHC was performed on a tissue microarray containing matched normal, marginal and tumour tissues. …”
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242
High-Resolution Genomic Profiling of Chromosomal Abnormalities in Human Stem Cells Using the 135 K StemArray
Published 2012-01-01“…Here, we describe an improved version of our StemArray, a stem-cell-focused comparative genomic hybridization (aCGH) microarray, which contains 135,000 probes and covers over 270 stem cell and cancer related genes at the exon level. …”
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243
Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma.
Published 2016-01-01“…A microarray expression analysis and functional annotation of differentially expressed genes identified several biological pathways where serglycin may be important. …”
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244
Integration of the transcriptome and glycome for identification of glycan cell signatures.
Published 2013-01-01“…The model further elucidated limitations in the two analytical platforms including a defect in the microarray for detecting the GnTV (MGAT5) enzyme. Our results demonstrate the potential of systems glycobiology tools for elucidating key glycan biomarkers and potential therapeutic targets. …”
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245
Peroxisome proliferator-activated receptor gamma coactivator-1 alpha acts as a tumor suppressor in hepatocellular carcinoma
Published 2017-04-01“…In addition, the expression levels of 21,400 genes in tissues and cells were detected by microarray. It was shown that peroxisome proliferator-activated receptor gamma coactivator-1 alpha expression was significantly downregulated in hepatocellular carcinoma compared with normal liver tissues. …”
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246
Clinical case of distal arthrogryposis in combination with epilepsy due to an unbalanced translocation
Published 2022-07-01“…This clinical observation demonstrates an opportunity of using innovative molecular cytogenetic technologies in the search for disease-related genetic causes in the absence of mutations detected by whole exome sequencing.…”
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247
A retrospective analysis of 6942 amniocentesis cases
Published 2025-08-01“…Among the single-method cases, Chromosomal Microarray Analysis (CMA) was the most frequently selected technique (14.18%). …”
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248
Comprehensive computational analysis reveals H5N1 influenza virus-encoded miRNAs and host-specific targets associated with antiviral immune responses and protein binding.
Published 2022-01-01“…H5N1 virus (H5N1V) is highly contagious among birds and it was first detected in humans in 1997 during a poultry outbreak in Hong Kong. …”
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249
Development of HuMiChip for functional profiling of human microbiomes.
Published 2014-01-01“…Additionally, HuMiChip was able to detect gene families at as low as 0.001% relative abundance. …”
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250
The Correlation Analysis Between m6A Methylation Modification and Ferroptosis Induced by Cigarette Smoke in Human Bronchial Epithelium
Published 2024-12-01“…The ROS, GSH, MDA, and total iron content were detected by relevant detection kits. The expression levels associated with ferroptosis and m6A methylation modification‐related genes were determined via reverse transcription‐quantitative polymerase chain reaction and western blot. …”
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251
Efficacy and tolerability of rufinamide in the treatment of epilepsy (experience of the Svt. Luka’s Institute of Child Neurology and Epilepsy)
Published 2018-11-01“…We assume that the early introduction of rufinamide (prior to the detection of drug resistance) might have yielded better results.…”
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252
Prevalence and characteristics of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) isolated from chicken meat in the province of Quebec, Canada.
Published 2020-01-01“…In addition to beta-lactam resistance, tetracycline and spectinomycin resistance was detected in all isolates from the 3 positive samples of the ST398 profile. …”
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253
Gene Expression Changes Induced by PPAR Gamma Agonists in Animal and Human Liver
Published 2010-01-01“…Several studies have been conducted using PCR analysis and microarray technology to identify possible target genes and here we review the data obtained from various in vivo and in vitro experimental models. …”
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254
Multiple colonization with S. pneumoniae before and after introduction of the seven-valent conjugated pneumococcal polysaccharide vaccine.
Published 2010-07-01“…Serotypes were identified by agglutination, multiplex PCR and microarray.<h4>Principal findings</h4>Rate of multiple colonization remained stable up to three years after PCV7 introduction. …”
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255
Herpes simplex virus type-1 infection and spread in a novel porcine corneal explant model is restricted to the epithelium.
Published 2025-05-01“…We infected these corneas topically via high-density microarray patches (HD-MAPs) dipped in GFP-labelled HSV-1. …”
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256
Lack of effect of the Salmonella deubiquitinase SseL on the NF-κB pathway.
Published 2013-01-01“…To attempt to clarify these discrepancies, we compared mRNA levels in mouse primary bone marrow-derived macrophages infected with wild-type or sseL mutant strains using a genome-wide microarray. There was no detectable effect of loss of SseL on mRNA levels corresponding to any known NF-κB-regulated gene. …”
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257
Sensitive and precise quantification of insulin-like mRNA expression in Caenorhabditis elegans.
Published 2011-03-01“…We validated the platform using 53 RNA samples previously characterized by high density oligonucleotide microarray analysis. For this set of genes and the standard nCounter protocol, sensitivity and precision were comparable between the two platforms. …”
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258
CHD1 contributes to intestinal resistance against infection by P. aeruginosa in Drosophila melanogaster.
Published 2012-01-01“…Evidence for a role as transcriptional regulator comes from its colocalization with elongating RNA polymerase II as well as from studies of fly Hsp70 transcription. Here we used microarray analysis to identify target genes of CHD1. …”
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259
Xirp proteins mark injured skeletal muscle in zebrafish.
Published 2012-01-01“…Through the use of Xirp1 and Xirp2a as markers, myocellular injury can now be detected, even though functional studies indicate that these proteins are not essential in this process. …”
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260
High prevalence of multidrug-tolerant bacteria and associated antimicrobial resistance genes isolated from ornamental fish and their carriage water.
Published 2009-12-01“…The quinolone and fluoroquinolone resistance gene, qnrS2, was detected at high frequency (37% tested recent isolates were positive by PCR). …”
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