Elevated thiamine level is associated with activating interaction between HIF-1α and SLC19A3 in experimental myopic guinea pigs by Zhongyu Ma, Jiawen Hao, Zhaohui Yang, Miao Zhang, Ruixue Zhang, Jizhao Xin, Bo Bao, Xuewei Yin, Xuewei Yin, Hongsheng Bi, Hongsheng Bi, Hongsheng Bi, Dadong Guo, Dadong Guo, Dadong Guo, Dadong Guo

“…Immunofluorescence and immunohistochemistry detected the expression of SLC19A3 and SLC19A3 in choroidal tissues at different modeling times, and protein immunoprecipitation and molecular docking verified the interactions between HIF-1α and SLC19A3.ResultsCompared with the normal control (NC) group, the LIM group guinea pigs showed a significant increase in axial length and decrease in refractive error, as well as a thinning of choroidal thickness and loosening of tissue structure. …”
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La presencia de mitos relacionados con la Actividad Física y el Deporte en estudiantes del ciclo formativo de grado medio y superior (The presence of misconceptions related to phys... by Marta García Tomás, Luis Rodiles Guerrero, Beatriz Bachero Mena

“…Además, podemos afirmar, que una gran mayoría de los errores, se dan dentro de las preguntas con relación al entrenamiento de fuerza. …”
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Comparative analysis of digital mammography and contrast-enhanced mammography in diagnosing suspicious breast calcifications: implications for surgical decision-making by Marwa Mohamed Taher Mohamed ElSayad, Maha Hussein Mohamed Helal, Omar Hussein Omar, Ahmed Gamal Eldeen Othman, Marwa Elsayed Abdelrahman Ibrahim

“…While Digital Mammography (DM) remains the gold standard for detecting breast microcalcifications, its ability to differentiate between benign and malignant types based solely on morphology and distribution is limited. …”
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Validation of Gait Kinematics With Ramp and Stair Ascent and Descent Revealed by Markerless Motion Capture in Simulated Living Space: Test-Retest Reliability Study by Daiki Shimotori, Kenji Kato, Tatsuya Yoshimi, Izumi Kondo

“…The absolute reliability of day-to-day reproducibility was assessed using full-curve analysis (root mean square difference [RMSD]) and discrete point analysis of gait events using the standard error of measurement (SEM). SEM was calculated only for level walking and ramp ascent and descent, where gait events were correctly detected. …”
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Dynamic Monitoring of Goaf Stress Field and Rock Deformation Driven by Optical Diber Sensing Technology by Jing Chai, Zhe Yan, Yibo Ouyang, Dingding Zhang, Jianfeng Yang, Gaoyi Yang, Chenyang Ma

“…High-precision optical fiber sensing detected an ultimate strain threshold of 4000 με for key stratum failure, with pre-fracture strain measurements consistently below this threshold. …”
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Evaluating the effectiveness of mass drug administration on lymphatic filariasis transmission and assessment of post-mass drug administration surveillance in Nigeria’s Federal Capi... by Juliana Ajuma Amanyi-Enegela, Joseph Kumbur, Faizah Okunade, Donald Ashikeni, Rinpan Ishaya, Girija Sankar, William Enan Adamani, Moses Aderogba, Louise Makau-Barasa, Achai Emmanuel, Bosede Eunice Ogundipe, Chinwe Okoye, Babar Qureshi

“…In TAS 2 (Abaji and Kuje), a single LF-positive case was detected in Abaji, still below the critical threshold. …”
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Randomised controlled trial of standard outpatient cardiac rehabilitation versus personalised cardiac rehabilitation for secondary prevention for all in need (SPAN) after type 1 my... by David Brieger, Tom Briffa, Julie Redfern, Derek P Chew, John Atherton, Jamie Rankin, Charley Budgeon, Andrew Maiorana, Anne Cordingley, Stephen Nicholls, Graham Hillis, Teagan Robinson, Tom Gilbert, Sam Lehman

“…To detect this difference of 15%, we require a sample size of 478 participants (239 per arm). …”
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Biofilm Formation in Dairy: A Food Safety Concern—Insights into the prevalence of Pseudomonadota and yeasts on milking system surface biofilms by Mérilie Gagnon, Samuel Jean, Juan de Toro-Martín, Gisèle LaPointe, Évelyne Guévremont, Simon Dufour, Denis Roy

“…Biofilms were predominantly detected in milk pipelines and milking machines (milk pipeline: 5.42 log gene copy number/swab; milking machine: 5.16 log gene copy number/swab), with greater bacterial loads quantified by quantitative PCR in fall than spring or summer. …”
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Evaluating the efficacy of bioelectrical impedance analysis using machine learning models for the classification of goats exposed to Haemonchosis by Aftab Siddique, Phaneendra Batchu, Arshad Shaik, Priyanka Gurrapu, Tharun Tej Erukulla, Cornileus Ellington, Andrea L. Rubio Villa, Davia Brown, Ajit Mahapatra, Sudhanshu Panda, Eric Morgan, Jan Van Wyk, David Shapiro-Ilan, Govind Kannan, Thomas H. Terrill

“…The BIA data revealed significant differences in Rs and Xc between lightly and more heavily Unhealthy goats, with the latter exhibiting elevated resistance values, likely due to dehydration and tissue changes resulting from Haemonchosis. These findings highlight the potential of BIA combined with machine learning to develop a scalable, rapid, and non-invasive diagnostic tool for monitoring small ruminant health, particularly in detecting parasitic infections like H. contortus. …”
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Graph-Based 3-Dimensional Spatial Gene Neighborhood Networks of Single Cells in Gels and Tissues by Zhou Fang, Kelsey Krusen, Hannah Priest, Mingshuang Wang, Sungwoong Kim, Anirudh Sriram, Ashritha Yellanki, Ankur Singh, Edwin Horwitz, Ahmet F. Coskun

“…Objective: We developed 3-dimensional spatially resolved gene neighborhood network embedding (3D-spaGNN-E) to find subcellular gene proximity relationships and identify key subcellular motifs in cell–cell communication (CCC). …”
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Investigating Spatial Effects through Machine Learning and Leveraging Explainable AI for Child Malnutrition in Pakistan by Xiaoyi Zhang, Muhammad Usman, Ateeq ur Rehman Irshad, Mudassar Rashid, Amira Khattak

“…Secondly, Spatial Durbin Error Model (SDEM) was used to detect and capture the impact of spatial spillover on childhood stunting. …”
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Analysis of Ionospheric Disturbances in China During the December 2023 Geomagnetic Storm Using Multi-Instrument Data by Jun Tang, Sheng Wang, Jintao Wang, Mingxian Hu, Chaoqian Xu

“…These findings demonstrate the substantial impact of ionospheric disturbances on GNSS positioning accuracy in southern and central China during the geomagnetic storm. …”
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Neural connectivity biotypes: predictors of clinical outcomes and improvement patterns of iTBS treatment in adolescents and young adults with depression by Xiaoyu Chen, Min Zhang, Fan Zhang, Yanling Zhou, Yuping Ning, Roger S McIntyre, Hanna Lu, Haiyan Liu, Yiying Chen, Xiaofeng Lan, Chengyu Wang, Weicheng Li, Zhibo Hu, Siming Mai, Yanan Yin, Zerui You, Guanxi Liu, Zhanjie Luo, Yexian Zeng, Yifang Chen, Robin Shao

“…A significant subgroup×treatment interaction related to symbol coding improvement was detected (F=5.22, p=0.026). Within subgroup 1, the active group showed significantly greater improvement in symbol coding compared with the sham group (t=2.30, p=0.028), while baseline levels of interleukin-6 and C-reactive protein emerged as significant indicators for predicting improvements in symbolic coding (R2=0.35, RMSE (root-mean-square error)=5.72, p=0.013). …”
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Correlation of Cartridge Based Nucleic Acid Amplification Test Grading Based on Cycle Threshold Value with Clinicoradiological Profile and Time to Culture Positivity in Pulmonary T... by Mohammed Javed Qureshi, Bhanu Pratap Choudhary, Chand Bhandari, Harsh Maheshwari, Manoj Saini, Dheeraj Merotha

“…Conversely, low bacillary loads were characterised by higher CBNAAT CT values, milder radiological findings and reduced sputum microscopy grading. These findings underscore the utility of these variables in distinguishing between low and high bacillary load cases. …”
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Reliability of Average Daily Steps Measured Through a Consumer Smartwatch in Parkinson Disease Phenotypes, Stages, and Severities: Cross-Sectional Study by Edoardo Bianchini, Domiziana Rinaldi, Lanfranco De Carolis, Silvia Galli, Marika Alborghetti, Clint Hansen, Antonio Suppa, Marco Salvetti, Francesco Ernesto Pontieri, Nicolas Vuillerme

“…Intraclass correlation coefficient (ICC; 3,k), standard error of measurement (SEM), and minimal detectable change (MDC) were used to evaluate the reliability of avDS for each subgroup. …”
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Repeatability and reproducibility of brain age estimates in multiple sclerosis for three publicly available models by Lonneke Bos, David R. van Nederpelt, J.H. Cole, E.M.M. Strijbis, B. Moraal, J.P.A. Kuijer, B.M.J. Uitdehaag, F. Barkhof, A.M. Wink, H. Vrenken, B. Jasperse

“…Variance component analyses were used to determine the standard error of measurement (SEM) and the smallest detectable change (SDC).Brain-PAD was higher for pwMS compared to HC when predicted with brainageR and DeepBrainNet, not when predicted with the MIDI-model. …”
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Effects of Inertial Measurement Unit Location on the Validity of Vertical Acceleration Time-Series Data and Jump Height in Countermovement Jumping by Dianne Althouse, Cassidy Weeks, Steven B. Spencer, Joonsun Park, Brennan J. Thompson, Talin Louder

“…No systematic bias was detected between the JH estimates derived from the best-performing IMU models and those obtained from the force platform (<i>p</i> = 0.91–0.99). …”
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Interleukin-4 and specific IgE to oranges levels study in persons with allergic anamnesis by A. S. Prilutskiy, N. B. Abylgazinova, K. Y. Tkachenko

“…Such findings support the evidence that IL-4 could play an important role in allergic response to orange proteins. …”
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Fatal HLH in patients with X-linked lymphoproliferative disease 1 due to a novel variant in SH2D1A: case report by Oksana Boyarchuk, Alla Volokha, Nataliia Yarema, Olga Dyvoniak, Tetyana Tomashivska, Ivanna Shymanska, Halyna Makukh, Jolan E. Walter, Jolan E. Walter

“…IntroductionX-linked lymphoproliferative disease type 1 (XLP1) is an inborn error of immunity (IEI) caused by pathogenic variants in the SH2D1A gene, leading to severe immune dysregulation, often triggered by Epstein-Barr virus (EBV) infection. …”
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Validity and Short-Term Repeatability of a Novel Hand-Held Respiratory Health Meter for the Assessment of Dynamic Maximal Respiratory Pressures in Healthy Young Adults by Ryynänen H, Sovijärvi A, Kuronen I, Ahokas EK, Valtonen M, Ihalainen JK, Multanen J

“…The short-term repeatability of the dMIP and dMEP in one week interval proved to be moderately good in terms of the coefficient of variation (CV), the intraclass correlation coefficient (ICC), the standard error of measurement (SEm) and minimal detectable change (MDC) (10.0%, 0.825, p&lt; 0.001, 7 cmH2O and 20 cmH2O and 9.1%, 0.895, p&lt; 0.001, 12 cmH2O and 34 cmH2O, respectively).Conclusion: The results indicate that the WellO2-RHM is a valid and repeatable method for the assessment of dMIP and dMEP in asymptomatic young adults, but the absolute values are lower than those obtained with devices measuring quasi-static MIP and MEP. …”
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