Research on the security governance system for the circulation of government data facing the risk of illegal export by WANG Yue, Mo Lijuan, SU Na

“…From a meso-level practical perspective, this study examines the storage and distribution of government data within government information systems. …”
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Effect of Biosynthesized Zinc oxide Nanoparticles on Phenotypic and Genotypic Biofilm Formation of Proteus mirabilis by Noor Hamza Faiq, Mais E. Ahmed

“…From all findings conducted by this study, zinc oxide nanoparticles can function as anti-bacterial agent in concentration dependent manner. …”
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Modelling cognitive decline in the Hypertension in the Very Elderly Trial [HYVET] and proposed risk tables for population use. by Ruth Peters, Nigel Beckett, Robert Beardmore, Rafael Peña-Miller, Kenneth Rockwood, Arnold Mitnitski, Shahrul Mt-Isa, Christopher Bulpitt

“…The probability of maintaining cognitive function, based on baseline function, was slightly higher in the actively treated group (e.g., for those with the fewest baseline errors, the chance of staying in that state was 63% for those on treatment, compared with 60% for those on placebo). …”
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Wavelength Demodulating Algorithm of FBG Dynamic Tuned by DFB Laser by ZHANG Jia-nan, XIONG Yan-ling, WU Ming-ze, LI Wei-bo

“…The central wavelength of the reflecting spectra in FBG was obtained by the standard Fabry-Perot transmission spectra based on the law between the dynamic scanning wavelength and scanning time of Distributed Feedback laser (DFB). The Gauss and Lorenz arithmetic function were used to investigate the Fabry-Perot transmission spectra and FBG reflecting spectra. …”
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Unveiling the role of NAD glycohydrolase CD38 in aging and age-related diseases: insights from bibliometric analysis and comprehensive review by Xianghui Zhao, Peiying Lv, Zixing Cai, Jun Dong, Wenxiang Chen, Liang Sun, Ruiyue Yang

“…Research articles were retrieved from the Web of Science database, followed by a bibliometric assessment using CiteSpace and VOSviewer to visualize key publication trends, contributions by countries and institutions, and keyword distributions. Based on the bibliometric analysis, key insights were synthesized to elucidate the role of CD38 in aging and age-related diseases, its underlying mechanisms, and its applications in clinical evaluation, detection methods, interventions, and therapeutic targets.ResultsThe bibliometric analysis revealed an exponential increase in the number of published articles over time, with the United States and China emerging as the leading research hubs. …”
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Design and Optimization of Intelligent High-Altitude Operation Safety System Based on Sensor Fusion by Bohan Liu, Tao Gong, Tianhua Lei, Yuxin Zhu, Yijun Huang, Kai Tang, Qingsong Zhou

“…By fusing five modes, it realizes the functions of safety status detection and precise positioning. …”
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Digital Twin-Based Technical Research on Comprehensive Gear Fault Diagnosis and Structural Performance Evaluation by Qiang Zhang, Zhe Wu, Boshuo An, Ruitian Sun, Yanping Cui

“…However, the current gear operation is still faced with problems such as poor monitoring, a single detection index, and low data utilization, which lead to incomplete evaluation results. …”
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A high content clonogenic survival drug screening identifies maytansine as a potent radiosensitizer for meningiomas by Jinxiu Yu, Jinxiu Yu, Jinxiu Yu, Jiaojiao Deng, Jiaojiao Deng, Jiaojiao Deng, Leihao Ren, Leihao Ren, Leihao Ren, Lingyang Hua, Lingyang Hua, Lingyang Hua, Tianqi Wu, Yi Hui, Chunlin Shao, Ye Gong, Ye Gong, Ye Gong, Ye Gong

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The effects of <i>Non3</i> mutations on chromatin organization in <i>Drosophila melanogaster</i> by A. A. Yushkova, A. A. Ogienko, E. N. Andreyeva, A. N. Pindyurin, A. E. Letiagina, E. S. Omelina

“…We analyzed the localization of the HP1 protein in Non3 mutants using DNA adenine methyltransferase identification (DamID) analysis and did not find substantial differences in protein distribution compared to the control. In hemocytes of Non3 mutants, we observed changes in the morphology of the nucleolus and in the size of the region detected by anti-centromere antibodies, but this was not accompanied by declustering of centromeres and their untethering from the nucleolar periphery. …”
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Role of iron in brain development, aging, and neurodegenerative diseases by Qiqi Gao, Yiyang Zhou, Yu Chen, Wei Hu, Wenwen Jin, Chunting Zhou, Hao Yuan, Jianshun Li, Zhenlang Lin, Wei Lin

“…Comprehending the role of iron in brain development, aging, and neurodegenerative diseases, utilizing iron-sensitive Magnetic Resonance Imaging (MRI) technology for timely detection or prediction of abnormal neurological states, and implementing appropriate interventions may be instrumental in preserving normal central nervous system function.…”
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Enhanced melanoma and non-melanoma skin cancer classification using a hybrid LSTM-CNN model by Sara M. M. Abohashish, Hanan H. Amin, E. I. Elsedimy

“…Time CNN layers are later used to extract spatial functions, such as texture, edges, and color variation, on each patch. …”
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LncRNA XIST promoted the stability of TLR9 mRNA in a FUS-dependent manner to facilitate aerobic glycolysis and proliferation in Th17/CD4+T cells by Wu Yan-ping, Ma Xiao, Han Si-ping, Wang Xiao-qin

“…ObjectiveTo explore the expression and function of lncRNA XIST in Th17 cells in IgA nephropathy （IgAN） and examine the regulation of lncRNA XIST on TLR9 mRNA expression.MethodsCD4+T cells were isolated from peripheral blood mononuclear cells （PBMCs） and induced to differentiate into Th17 cells.XIST was over-expressed and silenced by plasmid transfection.Proliferation and apoptosis of Th17 cells with different levels of XIST expression were detected by flow cytometry and CCK-8 assay.Levels of XIST，TLR9 mRNA and protein were detected by quantitative reverse transcription-polymerase chain reaction （qRT-PCR） and Western blot.The effect of XIST on TLR9 expression was predicted by luciferase report analysis and TLR9 mRNA half-life detection.Potential RNA-binding proteins interacting with XIST were searched through Starbase database and detected by RNA immunoprecipitation and Western blot.GraphPad8.0 was utilized for statistical analysis and variables were expressed as average±SD.Student T test or one-way ANOVA was employed.ResultsXIST was distributed predominantly in cytoplasm.It hinted that XIST might be involved in post-transcriptional regulation.A down-regulation of lncRNA XIST expression promoted apoptosis and DNA damage and arrested cell proliferation by regulating TLR9.With an over-expression of lncRNA XIST，TLR9 expression spiked and XIST up-regulated the expression of TLR9 by promoting the stability of TLR9 mRNA.As an RNA-binding protein （RBP），FUS interacted with XIST and FUS antibodies could significantly enrich XIST transcripts.A down-regulation of lncRNA XIST expression had no effect on FUS protein expression.It suggested that XIST might affect FUS function rather than expression.It was further confirmed that a down-regulation of XIST significantly reduced FUS-TLR9 mRNA binding and FUS over-expression rescued a down-regulation and degradation of TLR9 mediated by si-XIST.ConclusionlncRNA XIST and TLR9 play a critical role in Th17 cell proliferation in IgAN through a FUS-mediated signaling pathway.This finding provides new therapeutic ideas for IgAN..…”
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Decision making in frontotemporal dementia: neuropsychological and neuroimaging assessments by Shima Tavakolan Haghighi, Chiara Bertasini, Rozalda Picari, Giovanna Paolone

“…Frontotemporal dementia (FTD) is a neurodegenerative disorder primarily affecting the frontal and temporal lobes, leading to significant impairments in executive function, social behavior, and emotional regulation. …”
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Thermographic Insights into Degenerative Spinal Disorders: Evaluating the Diagnostic Potential of Digital Infrared Thermography Imaging by Sathish Muthu, Guna Pratheep Kalanchiam, Ashok Shyam

“…While DITI offers advantages such as real-time functional assessment, cost-effectiveness, and early disease detection, challenges related to standardization, environmental variability, and specificity persist. …”
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Multiwavelength Constraints on the Local Black Hole Occupation Fraction by Colin J. Burke, Priyamvada Natarajan, Vivienne F. Baldassare, Marla Geha

“…We develop a Bayesian model to infer the black hole occupation fraction assuming a broken power-law Eddington ratio distribution function. Our approach accounts for nondetections, incompleteness, and contamination from star-forming-related emission. …”
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More but Smaller: Marine Heatwaves Exacerbate Size Truncation in Overfished Fish Communities in the Skagerrak by Kjell Magnus Norderhaug, Portia Joy Nillos Kleiven, Thomas Wernberg, Ann‐Elin Synnes, Karen Filbee‐Dexter, Sigurd Espeland, Jonas Thormar, Kyrre Heldal Kartveit, Lene Christensen, Even Moland

“…Particular attention should be directed at changes in the distribution and function of foundation species due to their disproportionately important ecological roles. …”
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Multimodal imaging of dark without pressure in high myopia reveals evidence that photoreceptor microscopic lesions may be reversible by Qingge Guo, Xiuxiu Jin, Xiaoyu Xin, Xiaohong Guo, Shuai Ming, Yuxiang Li, Bo Lei

“…Abstract Dark without pressure (DWP) is the more darkly pigmented area of the retina in the fundus, typically exhibits relatively distinct boundaries, and varies in shape, size, and distribution across different individuals. Previous studies have concluded that DWP alone has no impact visual acuity, visual field, or other visual functions. …”
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Bright-Field Multiplex Immunohistochemistry in Swine PCV2 and PRRSV Lymphadenopathies by Giulia D’Annunzio, Luisa Vera Muscatello, Chiara Tugnoli, Stefano Pesaro, Andrea Luppi, Michelangelo Fiorentino, Tania Franceschini, Alessia Grillini, Gianluca Rugna, Giuseppe Sarli, Luciana Mandrioli

“…Multiplex immunostaining (mIHC) allows the simultaneous detection of multiple antigenic targets within the same tissue section, providing a deeper understanding of spatial variation in cellular distribution. …”
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Programming‐Assisted Imaging of Cellular Nitric Oxide Efflux Gradients and Directionality via Carbon Nanotube Sensors by Ivon Acosta Ramirez, Sruti Das Choudhury, Carley Conover, Omer Sadak, Nicole M. Iverson

“…The uniform fluorescence distribution of the nanoarray enables precise analysis of NO efflux directionality, both under and surrounding the cell. …”
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Crystallographic and Orientation Features of Nanocrystals in Thin Film Condensates PbTe-Bi2Te3 on Glass Ceramics by Ya.P. Saliy, D.M. Freik, І.S. Bylina, M.O. Galushchak

“…With the help of the AFM-images analysis, using the discrete Fourier transformation, the autocorrelation function for the azimuthal angle φ and the amount of normal distributions for the polar angle ρ we have investigated the orientation process of structure formation of the nanocrystals in vapor-phase condensates of PbTe-Bi2Te3 solid solution on glass ceramics. …”
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