Thermal Phase Curves in Hot Gas Giant Exoplanets Exhibit a Complex Dependence on Planetary Properties by Mark R. Swain, Kyle A. Pearson, Thaddeus D. Komacek, Geoffrey Bryden, Emeline Fromont, Gautam Vasisht, Gael Roudier, Robert T. Zellem

“…We present a catalog of uniformly processed 3.6 μ m and 4.5 μ m band exoplanet thermal phase curves based on Infrared Array Camera observations obtained from the Spitzer Heritage Archive. …”
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Genetic Association Analysis of Paratuberculosis Forms in Holstein-Friesian Cattle by Patricia Vázquez, Otsanda Ruiz-Larrañaga, Joseba M. Garrido, Mikel Iriondo, Carmen Manzano, Mikel Agirre, Andone Estonba, Ramón A. Juste

“…No significant association was detected between any SNP and the patent phenotype. …”
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The Rise of Nova V1674 Herculis by Robert M. Quimby, Brian D. Metzger, Ken J. Shen, Allen W. Shafter, Hank Corbett, Madeline Overton

“…High-cadence observations of novae from Evryscope and the planned Argus Array can record the diversity of rising nova light curves and help resolve how the interplay between thermonuclear fusion, binary interaction, and shocks power their earliest light.…”
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LIMFAST. III. Timing Cosmic Reionization with the 21 cm and Near-infrared Backgrounds by Guochao Sun, Adam Lidz, Tzu-Ching Chang, Jordan Mirocha, Steven R. Furlanetto

“…We show that this cross correlation can be detected at high significance by forthcoming 21 cm and NIRB surveys such as the Square Kilometre Array and SPHEREx. …”
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Association between Neuron-Specific Enolase Gene Polymorphism and Delayed Encephalopathy after Acute Carbon Monoxide Poisoning by Linlin Xu, Xuejiao Liu, Jing Zhao, Jiao Zeng, Jiapeng Gu, Xiaoli Zhang, Fan Zhang, Yongkai Han, Wenqiang Li, Ping Zhang, Renjun Gu

“…A total of 1,201 patients, including 416 in the DEACMP group and 785 in the acute carbon monoxide poisoning (ACMP) group, were detected by the Sequenom MassARRAY® method. The genotype frequencies and alleles of the 6 NSE SNPs (rs2071074, rs2071417, rs2071419, rs11064464, rs11064465, and rs3213434) were compared using different genetic models. …”
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Genetic Analysis of 'PAX6-Negative' Individuals with Aniridia or Gillespie Syndrome. by Morad Ansari, Jacqueline Rainger, Isabel M Hanson, Kathleen A Williamson, Freddie Sharkey, Louise Harewood, Angela Sandilands, Jill Clayton-Smith, Helene Dollfus, Pierre Bitoun, Francoise Meire, Judy Fantes, Brunella Franco, Birgit Lorenz, David S Taylor, Fiona Stewart, Colin E Willoughby, Meriel McEntagart, Peng Tee Khaw, Carol Clericuzio, Lionel Van Maldergem, Denise Williams, Ruth Newbury-Ecob, Elias I Traboulsi, Eduardo D Silva, Mukhlis M Madlom, David R Goudie, Brian W Fleck, Dagmar Wieczorek, Juergen Kohlhase, Alice D McTrusty, Carol Gardiner, Christopher Yale, Anthony T Moore, Isabelle Russell-Eggitt, Lily Islam, Melissa Lees, Philip L Beales, Stephen J Tuft, Juan B Solano, Miranda Splitt, Jens Michael Hertz, Trine E Prescott, Deborah J Shears, Ken K Nischal, Martine Doco-Fenzy, Fabienne Prieur, I Karen Temple, Katherine L Lachlan, Giuseppe Damante, Danny A Morrison, Veronica van Heyningen, David R FitzPatrick

“…Of these 42, the diagnoses were 31 individuals with aniridia and 11 individuals referred with a diagnosis of Gillespie syndrome (iris hypoplasia, ataxia and mild to moderate developmental delay). Array-based comparative genomic hybridization identified six whole gene deletions: four encompassing PAX6 and two encompassing FOXC1. …”
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Ultrasensitive interferons quantification reveals different cytokine profile secretion in inflammatory myopathies and can serve as biomarkers of activity in dermatomyositis by Loïs Bolko, Loïs Bolko, Loïs Bolko, Céline Anquetil, Céline Anquetil, Alba Llibre, Solène Maillard, Damien Amelin, Karim Dorgham, Vincent Bondet, Océane Landon-Cardinal, Océane Landon-Cardinal, Océane Landon-Cardinal, Ségolène Toquet, Ségolène Toquet, Kuberaka Mariampillai, Samuel Malatre, Alexandrine Mahoudeau, Baptiste Hervier, Mathieu Rodero, Guy Gorochov, Darragh Duffy, Olivier Benveniste, Olivier Benveniste, Yves Allenbach, Yves Allenbach

“…Patients were classified as active if PGA>5.Serum IFN-α and IFN-γ levels was measured using the single molecule array (SIMOA) technique. Serum IFN-β level was measured by Elisa. …”
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Hints of Planet Formation Signatures in a Large-cavity Disk Studied in the AGE-PRO ALMA Large Program by Anibal Sierra, Laura M. Pérez, Carolina Agurto-Gangas, James Miley, Ke Zhang, Paola Pinilla, Ilaria Pascucci, Leon Trapman, Nicolas Kurtovic, Miguel Vioque, Dingshan Deng, Rossella Anania, John Carpenter, Lucas A. Cieza, Camilo González-Ruilova, Michiel Hogerheijde, Aleksandra Kuznetsova, Giovanni P. Rosotti, Dary A. Ruiz-Rodriguez, Kamber Schwarz, Benoît Tabone, Estephani E. TorresVillanueva

“…Detecting planet signatures in protoplanetary disks is fundamental to understanding how and where planets form. …”
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Quality evaluation of Xishi Shijian tea based on fingerprint combined with chemical pattern recognition(基于指纹图谱结合化学模式识别的西施石笕茶品质评价) by 金英(JIN Ying), 黄铁军(HUANG Tiejun), 范文含(FAN Wenhan), 何乐芝(HE Lezhi), 马亚平(MA Yaping), 姚一建(YAO Yijian), 龚淑英(GONG Shuying), 王佳薇(WANG Jiawei), 范方媛(FAN Fangyuan)

“…The fingerprints of different grades of Xishi Shijian tea were established by detection of high performance liquid chromatography-fluorescence detector (HPLC-FLD), high performance liquid chromatography-ultraviolet (HPLC-UV) detector, ultrahigh performance liquid chromatography-diode array detector-mass spectrometry/mass spectrometry (UPLC-DAD-MS/MS) and gas chromatography-mass spectrometry (GC-MS). …”
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Naringin from Citrus maxima peel: a potential therapeutic agent for breast cancer via PKM2 inhibition by Flama Monteiro, Vijith Vittal Shetty, Ranjitha Acharaya, Sriram Naresh, Manne Munikumar, Shilpa S Shetty, Pradeep Nataranjan, Suchetha Kumari N

“…Abstract Introduction An extensive array of medicinal plants has undergone investigation, underscoring the imperative for the continued screening of natural inhibitors with the potential to target cancer metabolism. …”
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Differential expression of microRNAs in peripheral B lymphocytes in patients with IgA nephropathy and its clinical significance by WANG Qian-liao, CHEN Ting-yu, LI Gui-sen, WANG Li

“…Objective The aberrantly glycosylated IgA1 plays a crucial role in the pathogenesis of IgA nephropathy.In this study,we firstly identified the microRNAs expression profiles from peripheral blood B lymphocytes,and validated the differentially expressed candidate microRNAs in IgA nephropathy patients and healthy controls.Then we analyzed the relationship between the expression levels of these microRNAs with clinical parameters,pathological manifestations and serum aberrantly O-glycosylated IgA1 level.Methods CD19~+ B lymphocytes were isolated by Dynabeads CD19 magnetic beads from 7 IgA nephropathy patients and 4 healthy controls.Then the total RNA was extracted and the differential expression of microRNAs was detected by miRCURY LNA Array(v.18.0).Five candidate microRNAs were validated by QRT-PCR in 16 healthy controls and 29 IgA nephropathy patients.The relationships between expression levels of the five microRNAs and clinical-pathological parameters as well as serum galactose-deficient IgA1(Gd-IgA1) were analyzed.Results As compared with healthy controls,there were 115 significantly differentially expressed microRNAs in patients with IgA nephropathy,in which 85 upregulated and 30 downregulated.Five microRNAs,miR-3189-5p,let-7g-5p,miR-4258-5p,miR-4695-3p and miR-99b-5p were selected as candidates for further validation.The expression levels of the 5 candidate microRNAs showed no statistically significant different between IgA nephropathy patients and healthy controls.There was no statistically significant correlation between the expression levels of the 5 microRNAs and the clinicopathological parameters.The serum level of Gd-IgA1 in IgA nephropathy patients was significantly higher than in healthy controls.But there was no significant association between expression level of each microRNA and serum GdIgA1 level.Conclusions The microRNAs’ expression profile of peripheral blood B lymphocytes in IgA nephropathy patients was significantly different from healthy controls.Validation study showed that the expression of the five candidate microRNAs(miR-3189-5p,let-7g-5p,miR-4258-5p,miR-4695-3p and miR-99b-5p) weren’t significantly different between IgA nephropathy patients and healthy controls,and there was no significant association between the expression levels of the five microRNAs and clinicopathological parameters,as well as Gd-IgA1 level.It suggested that the five microRNAs might not be the crucial molecules for production of Gd-IgA1.…”
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Progression from isolated growth hormone deficiency to a combined pituitary hormone deficiency in a cohort of paediatrics patients with pituitary morphology abnormalities on MRI by Cristina Aguilar-Riera, Diego Yeste, Núria González-Llorens, Eduard Mogas, Ariadna Campos-Martorell, Paula Fernandez-Alvarez, Elida Vázquez, María Clemente

“…Array CGH was performed with eight patients (4 in the IGHD group and 4 in the CPHD group) and was negative in all patients. …”
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Serum reactivity to citrullinated protein/peptide antigens and left ventricular structure and function in the Multi-Ethnic Study of Atherosclerosis (MESA). by Jan M Hughes-Austin, Ronit Katz, Darcy S Majka, Michael H Criqui, William H Robinson, Gary S Firestein, W Gregory Hundley, Joachim H Ix

“…Serum reactivity to several citrullinated protein/peptide antigens has been identified in RA, which are detectable years before RA onset and in individuals who may never develop RA. …”
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GWAS analysis of Fusarium head blight resistance in a Nordic-Baltic spring wheat panel by Shayan Syed, Andrius Aleliūnas, Rita Armonienė, Gintaras Brazauskas, Andrii Gorash

“…QFHB-2AL.1 and QFHB-2BL.1 were stably detected in 11 trials. An overall total of 52 candidate genes was identified by analyzing QTL regions in combination with published transcriptome data. …”
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Vitamin D binding protein and receptor prevalence in a large population with periodontitis: single nucleotide polymorphism and transcriptomic profiling by Ziyan Nie, Xiaopan Hu, Peinan Hu, Peiqiang Li, Haijing Zhou, Xiaodong Xie

“…Genomic DNA was extracted from peripheral venous blood collected from each subject. A MassARRAY system was used to detect SNPs, including rs1544410G/A (BsmI), rs2228570C/T (FokI), rs7975232G/T (ApaI), rs731236T/C (TaqI), rs739837G/T, rs9729G/T, and rs3847987C/A in the VDR gene, and rs7041A/C in the VDBP gene. …”
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Fetal brain injury in the pump twin of a TRAP sequence with favorable postnatal outcome: a case report by Wirada Dulyaphat, Chaniga Jiratchayamaethasakul, Supakorn Chaiyakarn, Waranyu Lertrat, Chayada Tangshewinsirikul, Chaiyos Khongkhatithum

“…Serial biweekly transabdominal neurosonography remained unremarkable until 25 weeks, when bilateral ventriculomegaly was detected in the surviving fetus. Maternal TORCH screen and fetal SNP array were unremarkable. …”
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TAp63γ is the primary isoform of TP63 for tumor suppression but not development by Xinbin Chen, Wenqiang Sun, Xiangmudong Kong, Xin Ming, Yanhong Zhang, Wensheng Yan, Shakur Mohibi, Mingyi Chen, Keith Mitchell, Jin Zhang

“…While TAp63 and ΔNp63 are expressed as three TAp63α/β/γ and ΔNp63α/β/γ due to alternative splicing, only p63α (TA and ΔN) and p63γ (TA and ΔN) proteins are found to be detectable and likely to be responsible for p63-dependent activity. …”
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Clopidogrel and Aspirin Resistance and Its Interaction with Peripheral Arterial Disease Outcomes in the Indian Population by Vikram Patra, Rohit Mehra, C V N M Dattatraya, Rishi Dhillan, Anuka Sharma, Varun Sharma, Brijesh Biswas, Ajay Kumar Dabas, Rahul Merkhed

“…Patient samples were genotyped for clopidogrel resistance (CR)-associated single-nucleotide polymorphism (SNPs) using Illumina Global Screening Array Ver 3 Bead Chip. Illumina Infinium Genotyping Assay protocol was implemented. …”
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High sound pressure piezoelectric micromachined ultrasonic transducers using sputtered potassium sodium niobate by Fan Xia, Yande Peng, Wei Yue, Mingze Luo, Megan Teng, Chun-Ming Chen, Sedat Pala, Xiaoyang Yu, Yuanzheng Ma, Megha Acharya, Ryuichi Arakawa, Lane W. Martin, Liwei Lin

“…In this work, we present demonstrations in three fields: haptics, loudspeakers, and rangefinders. For haptics, an array of 15 × 15 KNN pMUTs is used as a non-contact actuator to provide a focal pressure of around 160.3 dB RMS SPL at a distance of 15 mm. …”
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Clinical Relevance of PCR Versus Culture in Urinary Tract Infections Diagnosis: Quantification Cycle as a Predictor of Bacterial Load by Pallavi Upadhyay, Arjuna Vallabhaneni, Edward Ager, Barbara Alexander, Adriana Rosato, Vijay Singh

“…For each dilution, quantitative cultures on solid media to confirm CFU/mL values and a real-time PCR UTI panel employing a nanofluidic Open Array^TM platform producing quantification cycle (Cq) values were performed. …”
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