Tobacco carcinogen NNK promotes pancreatic cancer proliferation via LINC00857/β-catenin by Cancan Zhou, Ruiqi Cao, Qiqi Wang, Jiantao Mo, Weikun Qian, Zhengyuan Feng, Shengzhan Zhang, Xin Chen, Jie Hao, Qingyong Ma, Zheng Wu, Zheng Wang

“…While long non-coding RNA LINC00857 (lnc RNA) is implicated in cancer progression, its regulation by NNK is unknown. …”
Get full text

Addiction to smartphones in Arabs is associated with severe depressive symptoms and insomnia: a cross-sectional study by Omar Gammoh, Salam Shannag, Sereene Al-Jabari, Rama Al-Shawaheen, Saleh Bazi, Ahmed Mohammad Al-Smadi, Albara Mohammad Ali Alomari

“…Mental health disturbance is an emerging factor implicated in smartphone addiction. Whether depressive symptoms and anxiety are implicated in smartphone addiction in developing countries such as Jordan is a nexus that warrants investigation. …”
Get full text

DeepAptamer: Advancing high-affinity aptamer discovery with a hybrid deep learning model by Xin Yang, Chi Ho Chan, Shanshan Yao, Hang Yin Chu, Minchuan Lyu, Ziqi Chen, Huan Xiao, Yuan Ma, Sifan Yu, Fangfei Li, Jin Liu, Luyao Wang, Zongkang Zhang, Bao-Ting Zhang, Lu Zhang, Aiping Lu, Yaofeng Wang, Ge Zhang, Yuanyuan Yu

“…Trained on comprehensive SELEX data, DeepAptamer outperformed existing models in accuracy as substantiated by experimental evidence. …”
Get full text

Tidally Heated Sub-Neptunes, Refined Planetary Compositions, and Confirmation of a Third Planet in the TOI-1266 System by Michael Greklek-McKeon, Shreyas Vissapragada, Heather A. Knutson, Akihiko Fukui, Morgan Saidel, Jonathan Gomez Barrientos, W. Garrett Levine, Aida Behmard, Konstantin Batygin, Yayaati Chachan, Gautam Vasisht, Renyu Hu, Ryan Cloutier, David Latham, Mercedes López-Morales, Andrew Vanderburg, Carolyn Heffner, Paul Nied, Jennifer Milburn, Isaac Wilson, Diana Roderick, Kathleen Koviak, Tom Barlow, John F. Stone, Rocio Kiman, Judith Korth, Jerome P. de Leon, Izuru Fukuda, Yuya Hayashi, Masahiro Ikoma, Kai Ikuta, Keisuke Isogai, Yugo Kawai, Kiyoe Kawauchi, Nobuhiko Kusakabe, John H. Livingston, Mayuko Mori, Norio Narita, Motohide Tamura, Noriharu Watanabe, Gareb Fernández-Rodríguez

“…Finally, we explore the corresponding implications for the formation and long-term evolution of the system, which contains two of the most favorable cool (<500 K) sub-Neptunes for atmospheric characterization with JWST.…”
Get full text

A Review of the Role of Neurotensin and Its Receptors in Colorectal Cancer by Shengyang Qiu, Gianluca Pellino, Francesca Fiorentino, Shahnawaz Rasheed, Ara Darzi, Paris Tekkis, Christos Kontovounisios

“…There is growing clinical data from human studies which corroborate the role NTS/NTSR plays in the development of human CRC. …”
Get full text

Nucleotide-induced hyper-oligomerization inactivates transcription termination factor ρ by Bing Wang, Nelly Said, Tarek Hilal, Mark Finazzo, Markus C. Wahl, Irina Artsimovitch

“…These and other recent data implicate aggregation as a widespread strategy to tune ρ activity.…”
Get full text

Causal relationship between inflammatory cytokines and posttraumatic stress disorder: a Mendelian randomization study and potential mechanism analysis by Yingchong Li, Bangliang Xu, Zhitao Chen

“…Genes POGZ and LRIG2 were identified as mediators, implicated in the TGF-beta signalling pathway.Conclusion: Our findings suggest a protective role of certain cytokines against PTSD and highlight potential molecular mediators. …”
Get full text

THE IMPACTS OF THE DEMOGRAPHIC CHARACTERISTICS OF RESIDENTS ON THE PERCEPTION OF QUALITY OF OFF-CAMPUS STUDENT ACCOMMODATION IN SOUTH-SOUTH, NIGERIA by O.C. BELLA-OMUNAGBE, Winston SHAKANTU, Marle VAN EYK, Amanda WERNER

“…It is limited to students who are currently residing in privately developed off-campus accommodation in selected universities, towns and cities in South-South, Nigeria. The data for this study were gathered between June and August, 2014 with the used of self-study structured questionnaire. …”
Get full text

Global burden of metabolic dysfunction-associated steatotic liver disease, 2010 to 2021 by Gong Feng, Giovanni Targher, Christopher D. Byrne, Yusuf Yilmaz, Vincent Wai-Sun Wong, Cosmas Rinaldi Adithya Lesmana, Leon A. Adams, Jerome Boursier, George Papatheodoridis, Mohamed El-Kassas, Nahum Méndez-Sánchez, Silvia Sookoian, Laurent Castera, Wah-Kheong Chan, Feng Ye, Sombat Treeprasertsuk, Helena Cortez-Pinto, Hon Ho Yu, Won Kim, Manuel Romero-Gómez, Atsushi Nakajima, Khin Maung Win, Seung Up Kim, Adriaan G. Holleboom, Giada Sebastiani, Ponsiano Ocama, John D. Ryan, Monica Lupșor-Platon, Hasmik Ghazinyan, Mamun Al-Mahtab, Saeed Hamid, Nilanka Perera, Khalid A. Alswat, Qiuwei Pan, Michelle T. Long, Vasily Isakov, Man Mi, Marco Arrese, Arun J. Sanyal, Shiv Kumar Sarin, Nathalie Carvalho Leite, Luca Valenti, Philip N. Newsome, Hannes Hagström, Salvatore Petta, Hannele Yki-Järvinen, Jörn M. Schattenberg, Marlen I. Castellanos Fernández, Isabelle A. Leclercq, Gulnara Aghayeva, Abdel-Naser Elzouki, Ali Tumi, Ala I. Sharara, Asma Labidi, Faisal M. Sanai, Khaled Matar, Maen Al-Mattooq, Maisam Waid Akroush, Mustapha Benazzouz, Nabil Debzi, Maryam Alkhatry, Salma Barakat, Said A. Al-Busafi, John Rwegasha, Wah Yang, Agyei Adwoa, Christopher Kenneth Opio, Mohammadjavad Sotoudeheian, Yu Jun Wong, Jacob George, Ming-Hua Zheng

“…Background &amp; Aims: This study used the Global Burden of Disease data (2010–2021) to analyze the rates and trends of point prevalence, annual incidence, and years lived with disability (YLDs) for metabolic dysfunction-associated steatotic liver disease (MASLD) in 204 countries. …”
Get full text

SUN-domain proteins of the malaria parasite Plasmodium falciparum are essential for proper nuclear division and DNA repair by Sofiya Kandelis-Shalev, Manish Goyal, Tal Elam, Shany Assaraf, Noa Dahan, Omer Farchi, Eduard Berenshtein, Ron Dzikowski

“…However, while the nuclear periphery of P. falciparum was implicated in several important functions, the role of the LINC complex in Plasmodium biology is unknown. …”
Get full text

Altered Production and Cellular Levels of Hydrogen Sulfide (H₂S) in Placental Trophoblasts from Pregnancies Affected by Pre-Eclampsia by Xiaodan Chu, Jie Xu, Xinggui Shen, Wenji Sheng, Jingxia Sun, Yang Gu, David F. Lewis, Danielle Cooper, Dani Zoorob, Yuping Wang

“…H₂S has been implicated in regulating placental vaso-activity and angiogenesis. …”
Get full text

Synergistic transcriptomic and metabolomic analyses in Zi geese ovaries with different clutch lengths by Shengjun Liu, Jiaxin Yin, Kexin Cong, Shan Yue, Yuanliang Zhang, Jinyan Sun, Xiaofang Ren, Ke Jiang, Yunuo Liu, Xiuhua Zhao

“…Integration of transcriptomic and metabolomic data revealed critical gene-metabolite pairs, including ACSL4–phosphoenolpyruvate, implicated in LCL regulation. …”
Get full text

Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats by Hong Yang, Cheng Zhang, Woonghee Kim, Mengnan Shi, Metin Kiliclioglu, Cemil Bayram, Ismail Bolar, Özlem Özdemir Tozlu, Cem Baba, Nursena Yuksel, Serkan Yildirim, Shazia Iqbal, Jihad Sebhaoui, Ahmet Hacımuftuoglu, Matthias Uhlen, Jan Boren, Hasan Turkez, Adil Mardinoglu

“…Excessive consumption of sucrose, in the form of sugar-sweetened beverages, has been implicated in the pathogenesis of metabolic dysfunction‐associated fatty liver disease (MAFLD) and other related metabolic syndromes. …”
Get full text

Amphetamine sensitization alters reward processing in the human striatum and amygdala. by Owen G O'Daly, Daniel Joyce, Derek K Tracy, Adnan Azim, Klaas E Stephan, Robin M Murray, Sukhwinder S Shergill

“…Dysregulation of mesolimbic dopamine transmission is implicated in a number of psychiatric illnesses characterised by disruption of reward processing and goal-directed behaviour, including schizophrenia, drug addiction and impulse control disorders associated with chronic use of dopamine agonists. …”
Get full text

THE MODEL OF ENTREPRENEURIAL MARKETING (EM) AMONG AGROPRENEURS IN THE EMERGING MARKETS: A CONCEPTUAL FRAMEWORK

“…Methodology â€“ This research will employ a mixed-method design through explanatory sequential approach. The data collection started with quantitative and followed by qualitative approach in order to achieve the study objectives.  …”
Get full text

Corporate governance and cost of equity capital: the mediation role of accounting conservatism by Jacobus Widiatmoko, Maria Goretti Kentris Indarti

“…The sample selection was carried out using the purposive sampling method, resulting in 230 data points and then tested using multiple linear regression. …”
Get full text

Does Adenosine Triphosphate via Purinergic Receptor Signalling Fuel Pulmonary Fibrosis? by Luke Forde, Debananda Gogoi, Rory Baird, Cormac McCarthy, Michael P. Keane, Emer P. Reeves, Emmet E. McGrath

“…This review amalgamates available data on the complex role of P1 and P2 purinergic receptor signalling in pulmonary fibrosis and discusses perspectives for novel treatments. …”
Get full text

Butanol isomers exert distinct effects on voltage-gated calcium channel currents and thus catecholamine secretion in adrenal chromaffin cells. by Sarah McDavid, Mary Beth Bauer, Rebecca L Brindley, Mark L Jewell, Kevin P M Currie

“…Butanol (C4H10OH) has been used both to dissect the molecular targets of alcohols/general anesthetics and to implicate phospholipase D (PLD) signaling in a variety of cellular functions including neurotransmitter and hormone exocytosis. …”
Get full text

Empowerment as an Intervening Variable of the Influence of Microfinance on the Economic Growth of Micro, Small, and Medium Enterprises by Musfiroh Mila Fursiana Salma, Billa Fatur Apriyana, Muslim Azis, Hinawati Titik, Sabrina Laila, Khabib Ainun

“…The population in this study were BSI KC Purwokerto Karangkobar customers, sampling technique with probability sampling type simple random sampling, so that the sample used was 100 respondents. Data collection was obtained from the results of distributing questionnaires to BSI KC Purwokerto Karangkobar customers. …”
Get full text

Relationships between Lecturer Performance, Organizational Culture, Leadership, and Achievement Motivation by Yusdi Anra, Martinis Yamin

“…This research was conducted using lecturers in Jambi University. The data were collected using a questionnaire as the research instrument. …”
Get full text