Causal relationships between alterations in shear stress-related genes and aneurysmal subarachnoid hemorrhage by Xiaoxin Wu, Yuanyuan Dai, Xingyang Niu, Minghao Zhang, Jiaoxing Li, Yi Xie, Wenli Sheng, Fei Ye

“…Abstract Background Current management of aneurysmal subarachnoid hemorrhage (aSAH) poses significant challenges, with emerging evidence implicating alterations in shear stress (SS) as critical in disease pathogenesis. …”
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Passive Smoking and the Development of Cardiovascular Disease in Children: A Systematic Review by Giorgos S. Metsios, Andreas D. Flouris, Manuela Angioi, Yiannis Koutedakis

“…Passive smoking may be implicated in the development of cardiovascular disease (CVD) in children because of their partially developed physiological systems. …”
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CDK6 kinase inhibition unmasks metabolic dependencies in BCR::ABL1+ leukemia by Lisa Scheiblecker, Thorsten Klampfl, Eszter Doma, Sofie Nebenfuehr, Omar Torres-Quesada, Sophie Strich, Gerwin Heller, Daniela Werdenich, Waltraud Tschulenk, Markus Zojer, Florian Bellutti, Alessia Schirripa, Sabine Zöchbauer-Müller, Peter Valent, Ingrid Walter, Eduard Stefan, Veronika Sexl, Karoline Kollmann

“…The cell cycle kinase CDK6 has recently been implicated in a wide range of hematopoietic malignancies. …”
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The role of major virulence factors and pathogenicity of adherent-invasive Escherichia coli in patients with Crohn’s disease by Khalid A. Abdelhalim, Ataç Uzel, Nalan Gülşen Ünal

“…Finally, we emphasise data on the prevalence of AIEC in CD patients.…”
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Financial and market risks of bitcoin adoption as legal tender: evidence from El Salvador by Griffin Msefula, Tony Chieh-Tse Hou, Tina Lemesi

“…This study analyzes monthly data from 2010 to 2022 using a structural vector autoregressive model, estimating Bitcoin’s pass-through into remittance, money multiplier, the US Dollar index, and gold price. …”
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A dataset of pollen production for 168 common flowering plants in the United Kingdom by Mathilde Baude, William Kunin, Nancy Davies, Ellen Wright, Jane Memmott

“…Our dataset consists of pollen volume per flower, calculated from the number of pollen grains and the volume of a pollen grain. Detailed data collection protocols are presented. Practical implication. …”
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Kontrol Keluarga dan Kemungkinan untuk Membayar Dividen: Pengaruh Volatilitas Arus Kas by Nunik Dwi Kusumawati

“…This study analyzed the data by using Logistic Regression and the sample by a purposive sampling in the sampling method. …”
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The factors that influence audit quality by earnings surprise benchmark by Vina Aqmarina, Reni Yendrawati

“…Then the technique of logistic regression was employed for data analysis. The research findings reveal that audit tenure and auditor rotation have a positive effect on audit quality, while age of publication has a negative effect on audit quality. …”
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The Nexus Between Government Revenue and Economic Growth in Nigeria by Joseph Fineboy Ikechi, Omodero Cordelia Onyinyechi

“…The study employs exploratory and ex-post facto research designs while using secondary form of data spanning from 1981 to 2018 collected from the Federal Inland Revenue Services (FIRS), National Bureau of Statistics and CBN statistical bulletin. …”
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Multiplex PCR assay to identify clinically important Aeromonas species by Aki Sakurai, Naoto Hosokawa, Daisuke Ohkushi, Sohei Harada, Yasufumi Matsumura, Naoya Itoh, Kazuhiro Ishikawa, Sho Saito, Takayuki Sakurai, Ryota Hase, Takehiro Hashimoto, Yohei Doi, Masahiro Suzuki

“…ABSTRACT The genus Aeromonas is increasingly implicated in human infections. However, accurate species-level identification remains challenging, particularly in clinical microbiology laboratories. …”
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Intracranial neurophysiological correlates of rumination: A cross-sectional observational study by Xiao Chen, Zhen Fan, Dong Chen, Liang Wang, Liang Chen, Chao-Gan Yan

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A comprehensive, population level evaluation of previously reported drug triggers of pemphigus highlights immunomodulatory capacity as a common characteristic by Justin Baroukhian, Kristina Seiffert-Sinha, Animesh A. Sinha

“…Despite anecdotal reports linking multiple drugs to PV, corroborating evidence from large datasets is missing.ObjectiveTo examine the extent to which previously reported associations between a comprehensive list of 36 drugs implicated in PV pathogenesis could be replicated using population-level pharmacovigilance data.DesignSeries of observational, retrospective, case-control, pharmacovigilance analyses (one analysis/drug, 36 total).SettingPopulation based.ParticipantsIndividuals who submitted a report of a drug-related adverse event to the FDA from Q4 of 2003 to Q2 of 2023.ExposureCases were identified by the presence of adverse events described by the MedDRA preferred term “pemphigus” (10034280) and then sorted based on exposure to each of the drugs of interest.Main outcomes and measuresReporting Odds Ratios (RORs) quantifying the association between a given drug exposure and reports of pemphigus adverse events.ResultsThe analyses revealed statistically significant associations between reports of pemphigus and exposure to 11/36 previously reported drugs, two of which had particularly high RORs (>200) [gold sodium thiomalate (ROR, 266.0; 95% CI, 202.6-349.3) and hydroxychloroquine (ROR, 282.6; 95% CI, 261.0-306.1)], three had very strong RORs (14-45) [penicillamine (ROR, 30.5; 95% CI, 11.4-81.7), piroxicam (ROR, 14.8; 95% CI, 8.2-26.7), and imiquimod (ROR, 42.3; 95% CI, 26.2-68.3)], and six had modestly strong RORs (2-5) [rifampin (ROR, 2.8; 95% CI, 1.4-5.6), hydrochlorothiazide (ROR, 1.6; 95% CI, 1.2-2.1), irbesartan (ROR, 2.7; 95% CI, 1.6-4.4), lisinopril (ROR, 5.3; 95% CI, 4.5-6.2), nivolumab (ROR, 2.7; 95% CI, 1.8-4.1), and nifedipine (ROR, 3.0; 95% CI, 1.9-5.0)]. …”
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Gut Microbiota in Autism Spectrum Disorder: A Systematic Review by Safae El Mazouri, Tarik Aanniz, Abdelhakim Bouyahya, Rachid El Jaoudi, Mahardian Rahmadi, Chrismawan Ardianto, Mouna Ouadghiri

“…There is increasing evidence of the implication of gut microbiota in ASD. We conducted a systematic review to summarize previously published data to compare the profile of gut microbiota between autistic and neurotypical subjects. …”
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Insulin like growth factor 2 mRNA binding protein 2 regulates vascular development in cerebral arteriovenous malformations by Lin-jian Wang, Lin-jian Wang, Lin-jian Wang, Yangyang Wu, Yangyang Wu, Yangyang Wu, Sha Xie, Hongkai Lian, Hongkai Lian, Hongkai Lian

“…Comprehensive bioinformatics analysis, integrating multi-omics data such as RNA-seq and methylated RNA immunoprecipitation sequencing (MeRIP-seq), was employed to identify the downstream target gene of IGF2BP2. …”
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Inter-Relationship Between Melanoma Vemurafenib Tolerance Thresholds and Metabolic Pathway Choice by Pratima Nangia-Makker, Madison Ahrens, Neeraja Purandare, Siddhesh Aras, Jing Li, Katherine Gurdziel, Hyejeong Jang, Seongho Kim, Malathy P Shekhar

“…Whereas β-catenin signaling induced TCA cycle and OXPHOS in highly drug tolerant A2058VemR cells, it activated pentose phosphate pathway in M14VemR cells with low vemurafenib tolerance, both of which are inhibited by ICG-001. These data implicate an important role for Wnt/β-catenin signaling in VemR-induced metabolic plasticity. …”
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Autophagy in Pancreatic Cancer by Daniel Grasso, Maria Noé Garcia, Juan L. Iovanna

“…This review summarizes recently published data in an attempt to clarify the importance of autophagy in this disease and try to reconcile apparently contradictory results.…”
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Rab3D is critical for secretory granule maturation in PC12 cells. by Tanja Kögel, Tanja Kögel, Rüdiger Rudolf, Erlend Hodneland, John Copier, Romano Regazzi, Sharon A Tooze, Hans-Hermann Gerdes

“…This strongly suggests that Rab3D is implicated in the subcellular localization and maturation of ISGs.…”
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The Effectiveness of the MGK Measure against the Odds Ratio in the Epidemiological Study by Bruce Masonova Solozafy Bemena, André Totohasina, Daniel Rajaonasy Feno

“…The result in this paper concerns only the study of probabilistic data.…”
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Mediators of Pruritus in Psoriasis by Adam Reich, Jacek C. Szepietowski

“…Many possible mediators were implicated to transmit or modulate this sensation in psoriasis, but none has been clearly proven to be a causative agent of itching. …”
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On the sparsity of synthetic control method by Qiang Chen, Wenjun Li

“…Synthetic Control Method (SCM) is a popular approach for causal inference in panel data, where the optimal weights for control units are often sparse. …”
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