Evaluation of the NHS England Low-Calorie Diet implementation pilot: a coproduced mixed-method study by Louisa J Ells, Tamara Brown, Jamie Matu, Ken Clare, Simon Rowlands, Maria Maynard, Karina Kinsella, Kevin Drew, Jordan R Marwood, Pooja Dhir, Tamla S Evans, Maria Bryant, Wendy Burton, Duncan Radley, Jim McKenna, Catherine Homer, Adam Martin, Davide Tebaldi, Tayamika Zabula, Stuart W Flint, Chris Keyworth, Mick Marston, Tanefa Apekey, Janet E Cade, Chirag Bakhai

“…Findings were triangulated with clinical data from the National Health Service England’s first cohort analysis (n = 7540). …”
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The Barcelona baseline risk score to predict long-term prognosis after a first demyelinating event: a prospective observational studyResearch in context by Carmen Tur, Pere Carbonell-Mirabent, Susana Otero-Romero, Álvaro Cobo-Calvo, María Jesús Arévalo, Helena Ariño, Georgina Arrambide, Cristina Auger, René Carvajal, Joaquín Castilló, Manuel Comabella, Ingrid Galán, Luciana Midaglia, Carlos Nos, Agustín Pappolla, Deborah Pareto, Jordi Río, Breogán Rodríguez-Acevedo, Estibaliz Saez de Gordoa, Ángela Vidal-Jordana, Ana Zabalza, Jaume Sastre-Garriga, Àlex Rovira, Xavier Montalban, Mar Tintoré

“…Methods: Using prospectively acquired data from the Barcelona first-attack cohort, we created the Barcelona-BRS model as a set of six Weibull survival models of time to an Expanded Disability Status Scale score of 3.0, built with flexible combinations of predictors, including sex, age at first attack, and number and topography of T2 lesions, among others, adaptable to data availability. …”
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Investigating the Neural Mechanisms of Self-Controlled and Externally Controlled Movement with a Flexible Exoskeleton Using EEG Source Localization by Takayuki Kodama, Masahiro Yoshikawa, Kosuke Minamii, Kazuhei Nishimoto, Sayuna Kadowaki, Yuuki Inoue, Hiroki Ito, Hayato Shigeto, Kohei Okuyama, Kouta Maeda, Osamu Katayama, Shin Murata, Kiichiro Morita

“…Conclusions: The flexEXO device and the comparison of brain activity under different conditions provide insights into the neural mechanisms of motor control and have implications for neurorehabilitation.…”
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Contribution of cuproptosis and immune-related genes to idiopathic pulmonary fibrosis disease by Chengji Jin, Jia Li, Qiaoyu Li, Lipeng Zhang, Shaomao Zheng, Qiong Feng, Yongjie Li, Yu Zheng, Qiuli Nie, Jin Liang, Jing Wang, Jing Wang

“…Cuproptosis, a novel form of copper-induced cell death, has garnered attention for its potential implications. The study aimed to explore the diagnostic value of cuproptosis-related hub genes in patients with IPF. …”
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EPHX1 enhances drug resistance to regorafenib by activating the JAK/STAT signaling pathway in hepatocellular carcinoma cell lines by Bin Xu, Xiangnan Liang, Wuguang Liu, BaiTong Wu, Qiuxiang Wang, Gong Kai, Chun Han, Binwen Sun, Bing Dong, Chengyong Dong, Liming Wang

“…Moreover, KEGG pathway enrichment analysis of DGE-seq data indicated that the JAK/STAT signaling pathway is crucial for EPHX1-induced regorafenib resistance. …”
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Comparative genomic analysis of emerging non-typeable Haemophilus influenzae (NTHi) causing emerging septic arthritis in Atlanta by Brianna J. Bixler, Charlotte J. Royer, Robert A. Petit III, Abraham G. Moller, Samantha Sefton, Stepy Thomas, Amy Tunali, Lauren F. Collins, Monica M. Farley, Sarah W. Satola, Timothy D. Read

“…We analyzed the genomic characteristics of C1 and C2 using whole genome sequencing data and compared them to a broader pangenome of H. influenzae strains to identify potential virulence factors and genetic adaptations. …”
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Enhancing Engagement, Practice Integration, and Skill Learning in Mobile Technology–Delivered Interventions Using Human Support: Randomized Controlled Trial With Depressed College... by Colleen S Conley, Brynn M DeLorenzo, Carol H Gonzales, Ian J Kahrilas, Jennifer Duffecy, Rebecca L Silton

“…MethodsParticipants (n=123) authorized access to their recorded app use data, provided by Headspace. In addition, at the midpoint (1 mo), postintervention (2 mo), and follow-up (3 mo) assessments, participants self-reported on the extent to which they had used the app, how likely they were to continue using the app and related skills in the future, and the extent to which they learned skills and practiced these skills in their daily lives. …”
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Intolerance of uncertainty and COVID-19-related post-traumatic stress disorder symptoms in US and Korean college students: serial mediation by COVID-19 concerns and loneliness by Ji Geun Kim, Hyunjung Yang, Deachul Seo, Gayeon Lee, Mijeong Park, Larkin S. McReynolds, Lawrence V. Amsel, Soo Hyun Park, Juyoen Hur, Young-Hoon Kim, Sanghoon Han

“…Methods The study included 448 college students from the US and 674 college students from Korea, aged 18 to 29, who completed an online survey measuring intolerance of uncertainty, COVID-19 concerns, loneliness, and COVID-19-related PTSD symptoms. Data were collected from September 2020 to May 2021 in the US and in August 2021 in Korea. …”
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Histopathological evaluation of the efficacy of carbon nanoparticle staining in detecting lymph node metastasis in colorectal cancer surgery by Qingzhao Feng, Xin Zhang, Shuyang Yang, Yingqi Feng, Hong Chen, Jiafeng Wang, Zijian Li, Shuang Fu, Qi Sun, Min Feng

“…Additionally, the study seeks to investigate the potential clinical implications of carbon nanoparticles (CNs) in the context of colorectal cancer surgery. …”
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Detection of plasmid-mediated mcr-1 gene in multidrug-resistant Escherichia coli from clinical specimens at a tertiary hospital in Nepal by Chetana Dahal, Sanjib Adhikari, Ramesh Sharma Regmi, Sanjeep Sapkota, Nabaraj Adhikari, Supriya Sharma, Megha Raj Banjara, Bimal Sharma Chalise, Prakash Ghimire, Komal Raj Rijal, Haijuan Wang

“…Despite its significance, data on colistin resistance and the prevalence of mobile colistin resistance (mcr) genes in Nepal are scarce. …”
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Internal structure, reliability and cross-cultural validity of the Warwick-Edinburgh Mental Wellbeing Scale in three European populations by Jose M Valderas, Katherine Pérez, Ioannis Bakolis, Gemma Vilagut, Jordi Alonso, Antonio J Molina, Vicente Martin, Philippe Mortier, Sarah Stewart-Brown, Alex Dregan, Xavier Bartoll, Amy Ronaldson, Antoni Serrano-Blanco, Jorge Arias de la Torre, Prateek Yadav, Cristina Casajuana Kogel, Joan Colom Farran, Carlos Garcia Forero, Lorena Botella-Juan, Line Nielsen, Beatriz Puertolas, Ziggi Santini, Ana Schiaffino

“…However, there is a lack of studies examining its metric performance and measurement invariance across countries.Objective This study aims to examine the internal structure, reliability and cross-country validity of the WEMWBS in three European populations.Methods WEMWBS data collected in 2016 from three representative population health surveys from an autonomous region in Spain (Catalonia) and two countries (Denmark and the UK) were used (n=13 940). …”
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Effects of PGK1 on immunoinfiltration by integrated single-cell and bulk RNA-sequencing analysis in sepsis by Yu Liu, Weijie Li, Lei Lei, Yaoliang Zhou, Mingcheng Huang, Yide Li, Xiaoying Zhang, Yingyu Jiang, Haiqi Wu, Zhihua Zheng, Kongyang Ma, Chun Tang

“…Phosphoglycerate kinase 1 (PGK1) has been implicated in regulating inflammation and immune cell infiltration in inflammatory conditions. …”
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TCF3 as a multidimensional biomarker: oncogenicity, genomic alterations, and immune landscape in pan-cancer analysis by Nie Huiling, Yu Yang, Zhou Siqi, Xu Yue, Chen Xi, Qin Xun, Liu Zhangyu, Huang Jiayu, Zhang Hailiang, Yao Jin, Jiang Qin, Wei Bingbing, Qin Xiaojian

“…We perform an exhaustive analysis of TCF3 expression, DNA variation profiles, prognostic implications, and associations with the TME and immunological aspects. …”
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The relationship between organizational trust and voice behavior among neonatal intensive care unit nurses in tertiary A hospitals in Sichuan Province: the mediating role of career... by Xiujuan Zhang, Xiujuan Zhang, Xi Huang, Xi Huang, Yanling Hu, Yanling Hu, Qiong Chen, Qiong Chen, Xiufang Zhao, Xiufang Zhao

“…Enhancing organizational trust and fostering career resilience among NICU nurses can improve their willingness to engage in voice behavior, ultimately leading to better healthcare outcomes.Implications for nursing managementNursing managers should foster a trusting and supportive work environment to improve nurses’ job satisfaction and organizational commitment. …”
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Longitudinal association of peripheral blood DNA methylation with liver fat content: distinguishing between predictors and biomarkers by Hailuan Zeng, Wenran Li, Mingfeng Xia, Jieyu Ge, Hui Ma, Lingyan Chen, Baishen Pan, Huandong Lin, Sijia Wang, Xin Gao

“…The study aimed to investigate longitudinal association of epigenome-wide DNAm with liver fat content (LFC) in Chinese participants, and explore their temporal relationships. Methods Data were obtained from 2 waves over a four-year time period of the Shanghai Changfeng Study (discovery, n = 407 and replication, n = 126). …”
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Simulation of thermal stratification and water temperature dynamics in the Joumine reservoir (Tunisia) by Haifa Madyouni, Pol Magermans, Sihem Benabdallah, Romdhane Mohamed Saleh, Hamadi Habaieb, Jean François Deliege

“…A comparison of model estimates and measured data indicates a bias due to distant meteorological stations and the exclusion of horizontal fluxes, such as water withdrawal and throughflow. …”
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Scoping review on assessing climate-sensitive health risks by Chalachew Yenew, Gashaw Melkie Bayeh, Asaye Alamneh Gebeyehu, Anley Shiferaw Enawgaw, Zufan Alamrie Asmare, Amare Genetu Ejigu, Tilahun Degu Tsega, Abathun Temesgen, Rahel Mulatie Anteneh, Zeamanuel Anteneh Yigzaw, Getasew Yirdaw, Sintayehu Simie Tsega, Ahmed Fentaw Ahmed, Almaw Genet Yeshiwas

“…This analysis was based on data from PubMed, Scopus, Web of Science and Cochrane Library, where appropriate, utilizing meta-extraction and Meta-analysis techniques. …”
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Is malathion oncogenic for mosquitoes? A transcriptomic and histological study of adults derived from malathion exposed larvae by Audrey Arnal, Erika Burioli, Lisa Jacquin, Sophie Labrut, Stéphane Duchon, Marie Rossignol, Delphine Nicolas, Beata Ujvari, Antoine Dujon, Jordan Meliani, Jérôme Abadie, Frédéric Thomas, Vincent Corbel

“…Understanding its sublethal and long-term effects is thus essential, both for evaluating its ecotoxicological impacts and for anticipating resistance mechanisms. However, empiric data on its effects in wild organisms - especially in invertebrates - remain limited. …”
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Prospective observational study of the challenges in diagnosing common neonatal conditions in Nigeria and Kenya by Melissa Gladstone, Janneke van de Wijgert, Nicholas D Embleton, Kevin Mortimer, Beatrice N Ezenwa, Isa Abdulkadir, Olusegun Akinyinka, Chinyere Ezeaka, Walter Otieno, Graham Devereux, Ismaela Abubakar, Iretiola B Fajolu, Zainab O Imam, Martha K Mwangome, Alison W Talbert, Grace M Nalwa, Helen M Nabwera, Stephen J Allen, Olukemi O Tongo, Abimbola E Akindolire, Chinyere V Ezeaka, Pauline EA Andang’o, Dominic D Umoru, Aimee P Staunton, Macrine Olwala, Pauline E A Andang'o

“…Clinicians completed forms for all admissions to their NNUs. Key data were displayed using heatmaps.Setting Five NNUs in Nigeria and two in Kenya comprising the Neonatal Nutrition Network.Participants 2851 neonates, which included all neonates admitted to the seven NNUs over a 6-month period.Results 1230 (43.1%) neonates had suspected sepsis, 874 (30.6%) respiratory conditions, 587 (20.6%) birth asphyxia and 71 (2.5%) abdominal conditions. …”
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The Practical, Robust Implementation and Sustainability (PRISM)-capabilities model for use of Artificial Intelligence in community-engaged implementation science research by Nabila El-Bassel, James David, Trena I. Mukherjee, Maneesha Aggarwal, Elwin Wu, Louisa Gilbert, Scott Walters, Redonna Chandler, Tim Hunt, Victoria Frye, Aimee Campbell, Dawn A. Goddard-Eckrich, Katherine Keyes, Shoshana N. Benjamin, Raymond Balise, Smaranda Muresan, Eric Aragundi, Marc Chen, Parixit Davé, David Lounsbury, Nasim Sabounchi, Dan Feaster, Terry Huang, Tian Zheng

“…Artificial Intelligence (AI) could enhance the collaborative process by improving data collection, analysis, insight, and engagement, while preserving research ethics. …”
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