Impact of Surgical Margin Status and Tumor Volume on Mortality After Robotic Radical Prostatectomy by Zaki Zeidan, Joshua Tran, Yeagyeong Hwang, Linda My Huynh, Mai Xuan Nguyen, Erica Huang, Whitney Zhang, Thomas Ahlering

“…Conclusions and clinical implications: Our study further challenges the belief that MPSMs inherently have an adverse impact on PCSM. …”
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Whole-genome sequencing reveals patterns of runs of homozygosity underlying genetic diversity and selection in domestic rabbits by Xinxin Ping, Yuan Chen, Hui Wang, Zhuoya Jin, Qianting Duan, Zhanjun Ren, Xianggui Dong

“…In this study, we analyzed whole-genome resequencing data from 117 rabbits to identify ROH patterns and inbreeding level across eleven rabbit breeds, including seven Chinese indigenous breeds and four exotic breeds, and to uncover selective signatures based on ROH islands. …”
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Prevalence, associated factors, and viral load dynamics of hepatitis B virus infection among HIV patients in three healthcare facilities of South Kivu province, eastern Democratic... by Parvine Basimane Bisimwa, Jean Paulin Mbo Mukonkole, Giscard Wilfried Koyaweda, Cadeau Mugisho Matabishi, Théophile Mitima Kashosi, Omari Mukanga, Denis Mukwege Mukengere, Jean Bisimwa Nachega, Narcisse Patrice Joseph Komas

“…Participants, on antiretroviral therapy, ART (TDF/3TC/DTG or AZT/3TC/LPV/r combinations) or newly diagnosed, consented for blood testing for hepatitis B using enzyme-linked immunosorbent assay (ELISA) and VLs using GeneXpert. Data were analyzed with Stata SE 14.0. Results The study found 8.0% HBsAg positivity among HIV patients in South Kivu, with 41.3% and 14.1% showing Anti-HBc and Anti-HBs, respectively. …”
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Determining household out of pocket payments, incidence of catastrophic expenditures and impoverishment among patients with malaria in Zambia's path towards Universal Health Covera... by Patrick Banda, Felix Masiye, Oliver Kaonga, Jesse Bump, Peter Berman

“…A household is considered impoverished if it fell below the poverty line due to OOP. All data was analyzed using Stata version 2013.<h4>Results and discussion</h4>The results show that although the country has a free malaria policy at primary care level and virtually at all levels if referred through the health system process, households are still incurring costs in accessing health care services. …”
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Aesthetic Investigation of the Pretarsal Shows and Morphology of Double Eyelids in Chinese Populations: A Questionnaire-based Survey by CHI Yarong, LI Zhujun, JIN Lin, YU Nanze, HUANG Jiuzuo, LONG Xiao

“…These findings hold significant implications for the planning of double eyelid surgeries, assessment of surgical outcomes, and evaluation of other periocular procedures associated with double eyelid surgeries.…”
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Undeliverable by design? How excessive internal medicine commitments are compromising Group 1 specialty training across the UK by Hasaan Rafique, Sadaf Hasaan, Neil Fisher

“…Annualised adjustments were made for leave, and all data were validated with Trust staffing teams. Results: No DGH met the 75:25 training time split in any year, while only one university hospital achieved this benchmark. …”
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Knockout of SIN3B modulates transcriptional programs and cell survival in cutaneous melanoma by Larissa Satiko Alcantara Sekimoto Matsuyama, Victoria Harle, Victoria Offord, Alastair Droop, Roy Rabbie, Manik Garg, Martha Estefania Vázquez-Cruz, Carla Daniela Robles-Espinoza, Gemma Turner, David Fraser, Érica Aparecida de Oliveira, Danielle Gonçalves de Carvalho, Natasha Andressa Nogueira Jorge, Mariana Boroni, Patricia A. Possik, David J. Adams, Silvya Stuchi Maria-Engler

“…Utilizing whole transcriptome data from melanoma patient samples we reveal that elevated levels of SIN3B are associated with poor survival outcomes with in vitro studies showing increased SIN3B expression in BRAF-mutant metastatic melanoma cell lines. …”
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The impact of stratified management of Ki-67 on the prognosis of small-cell lung cancer by Xiaofang Zhang, Mingyang He, Guanghua Zheng, Junjun Bai

“…Methods A total of 175 patients with SCLC who underwent surgical treatment were included in the study, with available data on the results of postoperative immunohistochemistry of the Ki-67 protein. …”
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Meta-analysis on the entomological effects of differentially treated ITNs in a multi-site experimental hut study in sub-Saharan Africa by Natalie Lissenden, John Bradley, Benjamin Menze, Charles Wondji, Constant Edi, Benjamin Koudou, Raphael N’Guessan, Koama Bayili, Abdoulaye Diabaté, Njelembo Mbewe, Basiliana Emidi, Jacklin Mosha, Alphaxard Manjurano, Graham Small, Welbeck Oumbouke, Sarah Jane Moore, Derric Nimmo, Janneke Snetselaar

“…Conclusions This meta-analysis showed that partially-treated net that restrict the insecticide treatment to specific panels of an ITN do not give equivalency or superiority in either mortality or blood-feeding inhibition to fully treated nets. The implications of these findings are discussed.…”
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First Molecular Evidence and Phylogeny of <i>Hepatozoon</i> sp. and <i>Theileria</i> sp. in Saudi Rodents by Sarra Farjallah, Abdulaziz Nasser Alagaili, Bandar H. AlOsaimi, Paolo Merella, Osama B. Mohammed, Nabil Amor

“…This study provides basic molecular data crucial to understanding host–parasite relationships and the potential public and veterinary health implications of these parasites in arid ecosystems.…”
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DNA Barcoding of Shark and Ray Species from Bawean and Masalembu Waters East Java by Marita Ika Joesidawati, Nining Nursalim, Nenik Kholilah, Marandi Eko Wibowo, Ni Kadek Dita Cahyani

“…The study underscores the importance of incorporating genetic diversity data into conservation strategies to protect these ecologically vital species in Indonesia.     …”
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Factors associated with health decision-making autonomy on own healthcare among Tanzanian women: A 2022-2023 demographic health survey study. by Tausi Seleman Haruna, Henry Ofori Duah, Rebecca Lee

“…<h4>Methods</h4>A non-experimental cross-sectional study using secondary data from the current Tanzania Demographic and Health Survey and Malaria Indicator Survey (TDHS-MIS) 2022-2023. …”
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Multistrain Probiotics and Telomere Length in Type 2 Diabetes: A 24-Week Randomized Controlled Trial by Venkata Chaithanya, Janardanan Kumar, Kakithakara Vajravelu Leela, Habeeb Ali Baig, Mohamed Soliman, Awwad Alenezy, Naglaa M. Shalaby

“…The primary outcome was telomere length, and secondary outcomes included hs-CRP and HbA1c levels. Data were analyzed using intention-to-treat (ITT) and per-protocol (PP) methods. …”
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Establishing a GMP-compliant manufacturing process and phase-appropriate analytics for early development of a FiCAR T-cell product with a novel CAR spacer by Annu Luostarinen, Arja Vuorela, Erja Kerkelä, Mimmi Patrikoski, Annika Kotovuori, Jan Koski, Jonna Ahoniemi, Kaarina Lähteenmäki, Jenni Lehtisalo, Terhi Oja, Henrik Paavilainen, Anu Autio, Marie Nyman, Veera Nikoskelainen, Virginie Kergourlay, Endrit Elbasani, Bert van Veen, Anil Thotakura, Hector Monzo, Päivi M. Ojala, Matti Korhonen, Heidi Hongisto, Anita Laitinen

“…Additionally, we present data on LP stability, which has broader implications for the development of various immune cell-based ATMPs.…”
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Digital Health Portals for Individuals Living With or Beyond Cancer: Patient-Driven Scoping Review by Steven Ouellet, Florian Naye, Wilfried Supper, Chloé Cachinho, Marie-Pierre Gagnon, Annie LeBlanc, Marie-Claude Laferrière, Simon Décary, Maxime Sasseville

“…ConclusionsWhile digital health portals enhance patient engagement, their clinical impact and equity implications remain insufficiently evaluated. We found disparities in functionalities, outcomes, and PROGRESS-Plus representation. …”
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Impact of Perioperative Glucagon-Like Peptide-1 Receptor Agonists on Postoperative Outcomes Following Carpal Tunnel Release by Nicholas C. Bank, MD, Stephen J. Perle, BS, Bradley J. Lauck, BA, Alecia J. Rajesh, BS, Alexander D. Jeffs, MD, Reid W. Draeger, MD

“…Purpose: Glucagon-like peptide-1 receptor agonist (GLP-1RA) use continues to rise because of its efficacy in glycemic control and weight reduction. There are sparse data on the implications of GLP-1RA therapy on surgical outcomes. …”
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Effect of the LifeSpan suicide prevention model on self-harm and suicide in four communities in New South Wales, Australia: a stepped-wedge, cluster randomised controlled trial by Helen Christensen, Michelle Torok, Matthew Phillips, Grant Sara, Andrew Page, Andrew Mackinnon, Henry Cutler, Alison L Calear, Isabel Zbukvic, Philip J Batterham, Lisa N Sharwood, Fiona Shand, Myfanwy Maple, Alexander Burnett, Brian Draper, Lauren McGillivray, Jiahui Qian, Stephanie Zeritis, Demee Rheinberger

“…Changes in rates of hospital presenting self-harm and suicide deaths were measured using linked administrative health data sets of persons aged 10 or older.Results Negative binomial regression models adjusted for linear trends and seasonality showed that LifeSpan was associated with a 13∙8% (incident response rate 0.86; 95% CI 0.79 to 0.94) reduction in hospital-presenting self-harm rates over the intervention period, compared with preintervention. …”
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Risk factors for mortality among kidney transplant recipients with COVID-19 in Saudi Arabia: a case-control study by Dema A. Alissa, Rawan Almasuood, Baraa Alghalyini, Hala Tamim, Mohammed Alaa Raslan, Abdul Rehman Zia Zaidi, Bader Abou Shaar, Mhd Malek Al Masri, Adnan Abdul Karim, Wejdan Aburas, Waled Aburas, Ahmed H. Al-jedai, Reem S. Almaghrabi

“…Further research is warranted to explore long-term implications and effective treatment protocols.…”
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Surface Soil Organic Carbon Estimation Based on Habitat Patches in Southwest China by Jieyun Xiao, Wei Zhou, Ting Wang, Yao Peng, Zhan Shi, Saibo Li, Yang Li, Tianxiang Yue

“…Utilizing multisource data and three machine learning models, we estimated soil organic carbon (SOC) content in southwest China. …”
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&ldquo;Doctor-Led, Patient-Centered&rdquo;: A Mixed-Method Research Comparing Patients&rsquo; and Doctors&rsquo; Treatment Outcome Choices for Chronic Low Back Pain by Li X, Zhang Y, Mao Z, Chen Q, Lan X, Chen H, Sun YN, Yu CH, Wang XY

“…Participants, including patients with any type of CLBP (age≥ 18) and doctors with at least one year of experience, were selected via purposive sampling. Quantitative data, analyzed with SPSS, were summarized as percentages for categorical variables and as means with standard deviations or medians for continuous variables. …”
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