Exercise stress echocardiography shows impaired left ventricular function after hospitalization with COVID‐19 without overt myocarditis: A pilot study by Robert E. Goldstein, Edward A. Hulten, Thomas B. Arnold, Victoria M. Thomas, Andrew Heroy, Erika N. Walker, Keiko Fox, Hyun Lee, Joya Libbus, Bethelhem Markos, Maureen N. Hood, Travis E. Harrell, Mark C. Haigney

“…To clarify status post‐hospitalization, we related exercise stress echocardiography (ESE) in 15 recovering patients (RP) age 30–63 without myocarditis to matching published data from healthy subjects (HS). RP exercise, average duration 8.2 ± 2.2 SD, was halted by dyspnea or fatigue. …”
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Water, sanitation, and hygiene insecurity and disease prevention behaviors during the COVID-19 pandemic in low-income neighborhoods of Beira, Mozambique. by Rebecca S Kann, Jedidiah S Snyder, Courtney Victor, Zaida A Cumbe, Joshua V Garn, Sandy McGunegill, Rassul Nalá, Matthew C Freeman, Karen Levy

“…In this study, which took place during the acute phase of the COVID-19 pandemic, we explore the relationship between control measures for global health crises and water, sanitation, and hygiene insecurity, with implications for other infectious diseases and future health emergencies.…”
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A novel lncRNA YIL163C enhances genomic stability and antifungal resistance via the DNA damage response in Saccharomyces cerevisiae by Xueting Wang, Xueting Wang, Xuemei Li, Duoyun Li, Yiying Zhang, Bing Bai, Bao Chai, Zewen Wen

“…Additionally, YIL163C reduced sensitivity to 5-fluorocytosine, indicating a role in antifungal drug tolerance. Phosphoproteomic data suggested YIL163C influences phosphorylation states, potentially acting downstream of the Mec1-Rad53 signaling pathway.ConclusionThis study provides new insights into the regulatory mechanisms of lncRNAs in DDR, with broader implications for antifungal therapy and genomic stability research, emphasizing the role of lncRNAs in stress responses beyond traditional protein-centric mechanisms.…”
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Interleukin-15 and cancer: some solved and many unsolved questions by Gabriella Pietra, Lorenzo Moretta, Nicola Tumino, Piera Filomena Fiore, Sabina Di Matteo, Francesca Romana Mariotti, Selene Ottonello, Simone Negrini, Barbara Bottazzi, Erwan Mortier, Bruno Azzarone

“…Therefore, in this review, we will discuss key unanswered issues on the heterogeneity and biological significance of IL-15 isoforms, analyzing both their cancer-related biological functions and their therapeutic implications.…”
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Polygenic risk scores in cardiovascular risk prediction: A cohort study and modelling analyses. by Luanluan Sun, Lisa Pennells, Stephen Kaptoge, Christopher P Nelson, Scott C Ritchie, Gad Abraham, Matthew Arnold, Steven Bell, Thomas Bolton, Stephen Burgess, Frank Dudbridge, Qi Guo, Eleni Sofianopoulou, David Stevens, John R Thompson, Adam S Butterworth, Angela Wood, John Danesh, Nilesh J Samani, Michael Inouye, Emanuele Di Angelantonio

“…We then modelled the implications of initiating guideline-recommended statin therapy in a primary care setting using incidence rates from 2.1 million individuals from the Clinical Practice Research Datalink. …”
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Shared genetic architecture between eating disorders, mental health conditions, and cardiometabolic diseases: a comprehensive population-wide study across two countries by Joeri Meijsen, Kejia Hu, Dang Wei, Stefana Aicoboaie, Helena L. Davies, Ruyue Zhang, Mischa Lundberg, Richard Zetterberg, Joëlle Pasman, Weimin Ye, Thomas Werge, Cynthia M. Bulik, Fang Fang, Alfonso Buil, Nadia Micali

“…This research enhances our understanding of comorbidity patterns and has important implications for developing integrated treatment approaches.…”
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Person-centered contraceptive counseling and associations with contraceptive practices among a nationally representative sample of women in Ethiopia by Celia Karp, Shira Tikofsky, Solomon Shiferaw, Assefa Seme, Mahari Yihdego, Linnea Zimmerman

“…Study design: This cross-sectional study uses nationally representative data collected by the Performance Monitoring for Action Ethiopia project among current and recent contraceptive users (n = 2731) aged 15–49 between October and November 2021. …”
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Can large-scale tree cover change negate climate change impacts on future water availability? by F. Engel, A. J. Hoek van Dijke, C. T. J. Roebroek, C. T. J. Roebroek, C. T. J. Roebroek, I. Benedict

“…Previous studies showed that global tree cover change can have large impacts on water availability under current climate conditions, but they did not touch upon the implications of global tree cover change under climate change. …”
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Geospatial and modelling analyses reveal diverse tick and tick-associated microbes in the East African Community by Abakundana Nsenga Ariston Gabriel, Xiao-Yang Wang, Guo-Yao Zu, Pei-Yu Zhen, Laila Jamil, Shi-Jing Shen, Cheng Li, Ntakirutimana Theoneste, Lin Zhao, Wu-Chun Cao

“…This study aimed to investigate the distribution of ticks and tick-associated microbes and to predict the potential extension of dominant tick species in the EAC. Methods Data were collected from literature reviews and related websites and analyzed using ArcGIS to generate maps showing the geographical distribution of ticks and associated microbes. …”
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iPSC-modelling reveals genetic associations and morphological alterations of oligodendrocytes in schizophrenia by Man-Hsin Chang, Jan Benedikt Waldeck, Marius Stephan, Nirmal Kannaiyan, Valéria de Almeida, Emanuel Boudriot, Temmuz Karali, Lukas Röll, Laura Fischer, Damianos Demetriou, Nadia Gabellini, Sabrina Galinski, Andrea Schmitt, Sergi Papiol, Daniel Keeser, Peter Falkai, Moritz J. Rossner, Florian J. Raabe

“…We performed unsupervised clustering analysis of hiPSC-differentiated neural cells including oligodendrocytes (iOLs) and their precursor cells (iOPCs) with corresponding human postmortem cell types from single-cell RNA sequencing (scRNAseq) data and conducted a comparative gene set enrichment analysis. …”
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Needs and Preferences of Swedish Young Adults for a Digital App Promoting Mental Health Literacy, Occupational Balance, and Peer Support: Qualitative Interview Study by Martin Karaba Bäckström, Sonya Girdler, Ben Milbourn, Annika Lexén

“…MethodsWe conducted semistructured interviews with 16 young adults and analyzed the data using reflexive thematic analysis. …”
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Epidemiology, fatality rate, and geographic distribution of Lassa fever in Anambra state, Nigeria by Chuma Edward Emembolu, Ijeoma Valentina Ikeanyionwu, Ben Afam Obidike, Obiageli Annamary Uchebo, Arinze Anthony Onwuegbuna, Onyeka Chukwudalu Ekwebene, Uchenna Clara Chijioke-Ofoma, Ngozichukwu Gertrude Uzoewulu, Chukwuemeka Chidindu Njoku, George Uchenna Eleje

“…Methods A retrospective cross-sectional study of surveillance data from the Surveillance Outbreak Response Management and Analysis System (SORMAS) was conducted for confirmed, suspected, and probable Lassa fever cases from 2018 to epidemiological week 41 of 2024. …”
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Multiple first-line therapeutic strategies to mitigate artemisinin resistance: cost analysis of a pilot study from a health system perspective in Kaya health district, Burkina Faso by Rosemonde M. Guissou, Jean Moïse T. Kaboré, Issiaka Soulama, Denise Hien, Yacouba Nombré, Alfred B. Tiono, Christian Burri, Sodiomon B. Sirima

“…Quantitative et qualitative data were collected through seven semi-structured and thirty-eight structured interviews. …”
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Effects of a Cloud-Based Synchronous Telehealth Program on Valvular Regurgitation Regression: Retrospective Study by Li-Tan Yang, Chi-Han Wu, Jen-Kuang Lee, Wei-Jyun Wang, Ying-Hsien Chen, Ching-Chang Huang, Chi-Sheng Hung, Kuang-Chien Chiang, Yi-Lwun Ho, Hui-Wen Wu

“…These findings may have important implications for future guidelines.…”
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Efficacy of Magnetic Seizure Therapy in Patients with Schizophrenia and Combined fMRI-EEG to Explore the Regulatory Mechanisms of Brain Networks by Wei S, Chen B, Guo Z, Zhang H, Li J, Hu X, Yang C, Li J, Li X, Liu Z, Xu Y, Liu S

“…Clinical symptoms, cognitive function, EEG and fMRI data were collected from the patient group at baseline, post-treatment and follow-up phases. …”
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Comprehensive analysis of glycometabolism-related genes reveals PLOD2 as a prognostic biomarker and therapeutic target in gastric cancer by Wanchun Ye, Xiaolei Zhang, Zhongjie Tang, Yufeng Hu, Yuanliang Zheng, Yuping Yuan

“…However, the specific roles of glycometabolism-related genes and their prognostic and therapeutic implications in GC remain inadequately understood. Methods Transcriptomic and clinical data from GC patients were retrieved from TCGA and GEO databases. …”
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Ukrainian black soils in war: assessing the impact of hostilities on violations of the guidelines for sustainable soil management by Anatolii Kucher

“…The following methods were used in the study: bibliometric using the VOSviewer software (to determine the status and clustering of studies on the impact of the Russian-Ukrainian war on soils and land based on the Scopus database); expert assessments (to determine the impact of hostilities on violations of the guidelines for sustainable soil management and soil quality); statistical (to process and present the results of expert assessment); calculation-analytical (to assess the damage and losses caused to soils due to Russian armed aggression); monographic and abstract-logical (to summarise the results of the study). The data was collected through an online survey of experts. …”
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SARS-CoV-2 genetic diversity and variants of concern in Saudi Arabia by Dalia Abdullah Obeid, Madain Saleh Alsanea, Rawan Talal Alnemari, Ahmed Ali Al-Qahtani, Sahar Isa Althawadi, Maysoon Saleh Mutabagani, Reem Saad Almaghrabi, Faten Mohammed Alhadheq, Basma Mohammed Alahideb, Fatimah Saeed Alhamlan

“…Our findings provide evidence to begin linking the evolutionary implications to host factors and their effects on the virus severity and transmission. …”
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Constructing a novel mitochondrial metabolism-related genes signature to evaluate tumor immune microenvironment and predict survival of colorectal cancer by Hou Wang, Hou Wang, Kai Zhang, Guang Ning, Guang Ning

“…BackgroundColorectal cancer (CRC) is a highly lethal gastrointestinal malignancy with substantial global health implications. Although mitochondrial metabolism genes play a crucial role in CRC development, their prognostic significance remains unclear.MethodsThis study systematically analyzed the expression and prognostic value of mitochondrial metabolism-related genes in CRC patients, establishing a risk model using data from TCGA and GEO databases. …”
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Comprehensive genomic epidemiology and antimicrobial resistance profiles of clinical Klebsiella pneumoniae species complex isolates from a tertiary hospital in Wenzhou, China (2019... by Weiyan Jiang, Yanhui Chen, Meimei Lai, Yongan Ji, Suzhen Lin, Jiao Shao, Xiaojian Chen

“…Our research fills critical gaps in the current understanding of KpSC epidemiology in China and offers valuable data for global comparative studies, contributing to the development of effective infection control measures. …”
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