Multihealth Promotion Programs on Physical Health and Quality of Life in Older Adults: Quasi-Experimental Study by Li-Yun Lee, Heng-Hsin Tung, George Liao, Su-Ju Liu, Zi-Yu Chen, Yea-Ru Yang

“…This study’s findings have significant implications for clinical practice. These findings can aid in the establishment of effective interventions for older adults. …”
Get full text

Roles of C-reactive protein and LOX-1 on cancer and myeloid-derived suppressor cells in the progression of uterine cervical cancer by Michihide Maeda, Seiji Mabuchi, Takashi Akazawa, Yu Mizote, Tomoyuki Sasano, Naoko Komura, Mina Sakata, Tsuyoshi Takiuchi, Shinya Matsuzaki, Tsuyoshi Hisa, Harumi Nakamura, Tomoya Ekawa, Shoji Kamiura, Tadashi Kimura, Hideaki Tahara

“…Abstract We investigated clinical implications of CRP and its receptor, LOX-1, in cervical cancer progression and the underlying mechanisms. …”
Get full text

A Whole-School Approach for the Promotion of Physical Activity: An Evaluation of Stakeholders’ and Educators’ Perceptions About Education in Six European Countries by Despoina Ourda, Lida Skoufa, Antonella Brighi, Diane Crone, Lowri Edwards, Alessandro Failo, Sophia Fourlari, Mikko Huhtiniemi, Timo Jaakkola, George Raptis, Paul Sellars, Elena Papacosta, Vassilis Barkoukis

“…There is a lack of empirical data on teachers’ opinions and needs regarding the implementation of a WSA approach to encourage physical activity. …”
Get full text

Distribution and Antimicrobial Resistance Analysis of Blood Culture Isolates at a Chinese National Cardiovascular Regional Medical Center: A 7-Year Retrospective Study by Wang Q, Wu F, Li T

“…Continuous antimicrobial resistance surveillance of bloodstream isolates should be maintained in clinical practice to provide evidence-based data for rational antibiotic use and mitigate the emergence of resistant pathogens.Keywords: bloodstream infections, antimicrobial resistance, multidrug-resistant organisms, antibacterial drugs…”
Get full text

Pan-immune-inflammation value and its association with all-cause and cause-specific mortality in the general population: a nationwide cohort study by Ye Zhang, Yong Yue, Yong Yue, Zhengyu Sun, Pengcheng Li, Xiaoyi Wang, Gang Cheng, Hailin Huang, Zongping Li

“…This study underscores the potential of PIV as a predictive biomarker for mortality risk, with implications for its use in clinical and epidemiological settings. …”
Get full text

Global, regional, and national burden of fracture of sternum and/or fracture of one or more ribs: a systematic analysis of incidence, YLDs with projections to 2030 by Zhizhi Wang, Yikuan Cai, Yu Tong, Huajie Li, Hu Zhou, Tongyin Ou, Tianlan Ye, Jiangsheng Zhang, Kaican Cai, Zhiming Chen

“…Despite their significant clinical and public health implications, epidemiological studies on these injuries remain limited. …”
Get full text

Subtype-specific analysis of gene co-expression networks and immune cell profiling reveals high grade serous ovarian cancer subtype linkage to variable immune microenvironment by Kaylin M. Carey, Corey D. Young, Alexis J. Clark, Eric B. Dammer, Rajesh Singh, James W. Lillard

“…Our study reveals the complex interplay between mRNA subtypes and suggests genes contributing to molecular subtypes, underscoring the important clinical implications of mRNA subtyping in HGSOC.…”
Get full text

Neonatal resuscitation skill among health care providers in Eastern Africa: A systematic review and meta-analysis by Addis Eyeberu, Elias Yadeta, Haymanot Mezmur, Aboma Motuma, Adera Debella

“…Methods: Articles were searched from major databases. Data were analyzed using Stata version 18 statistical software. …”
Get full text

Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner by Amy Fagan, Mariana Sponchiado, Luz Mata, Shanil Amin, J. Ignacio Aguirre, Sreekala Prabhakaran, Leah R. Reznikov

“…Mechanistic and complementary studies performed in NCI-H322 cells, a human cell line with “club cell-like” characteristics, failed to demonstrate a relationship among BDNF, IL-13 signaling, and Muc5ac at the mRNA level.ConclusionThese data highlight sex-dependent differences and club cell-specific effects of Bdnf in regulating airway physiology under inflammatory conditions in mice, suggesting that further studies are needed to understand potential translational implications.…”
Get full text

Statistical and health economic analysis plan for a secure care hospital evaluation of manualised (interpersonal) art-psychotherapy: the SCHEMA randomized controlled trial by Jennifer Condie, Matthew Franklin, Katie Aafjes-van Doorn, Paula Foscarini-Craggs, Iain McKinnon, Toni Leigh Harrison, Arman Iranpour, Ania Zubala, Sophie Rose, Elizabeth Randell, Rachel McNamara, Muhammad Riaz, Simon Hackett

“…Resource-use is collected based on secure care records, to estimate intervention and healthcare costs over 19 and 38 weeks. HRQoL and cost data will inform cost-effectiveness based on the incremental cost per quality-adjusted life year over 38 weeks. …”
Get full text

Association of the previous experience of maternal migration absence with non-suicidal self-injury (NSSI) in their school-aged children: a cross-sectional study in Anhui, China by Hailati Akezhuoli, Shi Guo, Honghui Zhao, Jiayao Xu, Qianwen Xie, Xudong Zhou, Jingjing Lu, Lu Li

“…Participants and setting Data were collected by a self-administrated questionnaire survey conducted among a school-based sample of students in the Anhui province, China. …”
Get full text

Applying the theoretical domains framework to identify determinants to mental healthcare use among older African Americans with type 2 diabetes: a qualitative study by Jamie Mitchell, Jaclynn Hawkins, Srijani Sengupta, Katherine A Kloss, Claudia Schwenzer, Fonda N Smith, Lenette M Jones, Robin Nwankwo, Gretchen A Piatt

“…Each session lasted 60–90 min and was transcribed and analysed.Participants The study included 30 African American adults (15 males and 15 females), aged 60 and above, living in an urban area in the Midwest.Primary and secondary outcomes The primary outcome was the identification of themes from participant responses, analysed using thematic content techniques and categorised into TDF constructs. Demographic data served as the secondary outcome.Results Nine key themes were identified, categorised under major TDF domains and constructs. …”
Get full text

Associations of medical outcomes with substances involved in suicide attempt cases age 50 and older reported to U.S. Poison Centers, 2016–2023 by Namkee G. Choi, Bryan Y. Choi, C. Nathan Marti, S. David Baker

“…In this study, we examined the medical outcome severities associated with different classes of substances involved in suicide attempt cases age 50 and older who were reported to poison centers.MethodsWe used the America's Poison Center's National Poison Data System from 2016 to 2023 (N = 335,171 cases age >50). …”
Get full text

Uncovering the factors of financial well-being: the role of self-control, self-efficacy, and financial hardship by Jorge Hernandez-Perez, Salvador Cruz Rambaud

“…Psychology Press, Philadelphia, pp 157–183, 2014), the Behavioral Life-Cycle Hypothesis (Shefrin and Thaler in Econ Inq 26:609–643. 10.1111/j.1465-7295.1988.tb01520.x, 1988; Thaler in Am Econ Rev 108:1265–1287, 2018), and Bandura’s Self-Efficacy Theory (in, Self-efficacy in changing societies, Cambridge University Press, Cambridge, 1997). Data were drawn from the Spanish Survey of Financial Literacy, a nationally representative sample of 8554 individuals. …”
Get full text

The interaction between temperature and rainfall determines the probability of tropical forest fire occurrence in Hainan Island by Xiaohua Chen, Xiaohua Chen, Qingqing Yang, Qingqing Yang, Zongzhu Chen, Jinrui Lei, Tingtian Wu, Yuanling Li, Xiaoyan Pan

“…These findings have important implications for global tropical forest management and fire prevention, aiding in the formulation of targeted control strategies.…”
Get full text

Operational cost savings: Blockchain-driven back-office automation and syndicated loan growth in U.S. banks by Maksym Ivasenko, Serhiy Frolov, Mykhaylo Heyenko, Nataliia Kolodnenko, Viktoriia Datsenko

“…This article highlights the results of a study investigating whether the growth of syndicated loan activity among US commercial banks was driven by measurable operational cost savings through blockchain-powered back-office automation. Quarterly data from Q1 2010 to Q4 2024 on syndicated loan stocks, commercial and industrial loans, real GDP, bank assets, and non-interest expenses were obtained from the Federal Reserve System’s FRED database. …”
Get full text

Transcriptome remodeling drives acclimation to iron availability in the marine N2-fixing cyanobacterium Trichodesmium erythraeum IMS101 by Xin Zhong, Ran Duan, Shengwei Hou, Meng Chen, Xiaoming Tan, Wolfgang R. Hess, Tuo Shi

“…By subjecting the model marine diazotroph Trichodesmium erythraeum IMS101 to increasing concentrations of supplemented Fe, we demonstrate in it a comprehensively remodeled transcriptome that drives the mobilization of cellular Fe for coordinated carbon and nitrogen metabolism and reallocation of energy and resources. Our data provide broad genomic insight into marine diazotrophs acclimation to Fe availability, enabling the versatility and flexibility in choice of indicator genes for monitoring Fe status in the environment and having implications on how marine diazotrophs persist into the future ocean.…”
Get full text

Longitudinal relationship between 24-Hour Movement behavior patterns and physical function and quality of life after stroke: a latent transition analysis by Yi Zhang, Lin Yao, Lei Chen, Weiying Zhong, Jiaxuan Li, Lan Xu, Xi Pan

“…The participants were asked to wear a wristband smartwatch for 7 consecutive days during each pe riod to collect 24-hour exercise data. After each period, their physical function and HRQoL were assessed. …”
Get full text

Nurturing compassion in neonatal end-of-life care: a qualitative exploration of palliative care nurses’ roles and experiences by Osama Mohamed Elsayed Ramadan, Alaa Hussain Hafiz, Nouran Essam Katooa, Nasreen M. Alghamdi, Nadia Bassuoni Elsharkawy, Enas Mahrous Abdelaziz, Nermen Abdelftah Mohamed, Nagwa Ibrahim Mabrouk Baraka

“…Forty nurses from four neonatal intensive care units (NICUs) in Egypt completed semi-structured interviews and reflective journaling. Data were analyzed using a two-phase approach, incorporating Lazarus and Folkman’s Transactional Model of Stress and Coping to contextualize findings within broader emotional regulation and resilience frameworks. …”
Get full text

A genetic exploration of the relationship between posttraumatic stress disorder and cardiovascular diseases by Eva Lukas, Rada R. Veeneman, Dirk J. A. Smit, Tarunveer S. Ahluwalia, Jentien M. Vermeulen, Gita A. Pathak, Renato Polimanti, Karin J. H. Verweij, Jorien L. Treur

“…We leveraged summary-level data of genome-wide association studies (PTSD: N = 1,222,882; atrial fibrillation (AF): N = 482,409; coronary artery disease (CAD): N = 1,165,690; hypertension (HT): N = 458,554; heart failure (HF): N = 977,323). …”
Get full text