Remote Monitoring for the Management of Spasticity: Challenges, Opportunities and Proposed Technological Solution by Kavit R. Amin, Samuel R. Smith, Amit N. Pujari, Syed Ali Raza Zaidi, Robert Horne, Atif Shahzad, Christopher Walshaw, Christy Holland, Stephen Halpin, Rory J. O'Connor

“…We established that a reliable ambulatory spasticity monitoring system that collates clinically meaningful data remotely would be useful in the management of this complex condition. …”
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Host cell interactions of outer membrane vesicle-associated virulence factors of enterohemorrhagic Escherichia coli O157: Intracellular delivery, trafficking and mechanisms of cell... by Martina Bielaszewska, Christian Rüter, Andreas Bauwens, Lilo Greune, Kevin-André Jarosch, Daniel Steil, Wenlan Zhang, Xiaohua He, Roland Lloubes, Angelika Fruth, Kwang Sik Kim, M Alexander Schmidt, Ulrich Dobrindt, Alexander Mellmann, Helge Karch

“…By demonstrating that naturally secreted EHEC O157 OMVs carry and deliver into cells a cocktail of biologically active virulence factors, thereby causing cell death, and by performing first comprehensive analysis of intracellular trafficking of OMVs and OMV-delivered virulence factors, we provide new insights into the pathogenesis of EHEC O157 infections. Our data have implications for considering O157 OMVs as vaccine candidates.…”
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Social appearance anxiety and body checking behavior in the relationship between social media addiction and depressive symptoms among college students by Xiaochen Wang, Yanan Wang, Shufei Yang, Zhen Li, Chang Fu

“…This research aims to address the gap in understanding how social media addiction influences mental health, particularly among college students.MethodsData from 1,456 students recruited from three universities in Shandong, China, were analyzed using structural equation modeling. …”
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Mapping Forest Fire Dynamics: A Global Perspective on Trends of Severity and Frequency Across Sub-Biomes by S. Mamgain, B. Ghale, A. Roy, H. C. Karnatak

“…This study presents a comprehensive analysis of forest fire trends for severity & frequency across sub-biomes globally, utilizing daily MODIS active fire data (2001-2023). The analysis integrates Mann-Kendall trend tests, Sen’s slope estimations, & spatial mapping to elucidate the patterns of forest fire occurrences & their implications for different ecosystems. …”
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Identification of individual-level clinical factors associated with increased risk of death during heatwaves: a time-stratified case-crossover study using national primary care rec... by Shakoor Hajat, Ross Thompson, Sari Kovats, Emer O’Connell, Helen Macintyre

“…Results presented have important implications for patient medication management during heat events, incorporating heat-risk considerations into other health policies such as suicide prevention plans and highlighted potential differences between clinical vulnerability and patients at risk.…”
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Efficacy of lasmiditan, rimegepant and ubrogepant for acute treatment of migraine in triptan insufficient responders: systematic review and network meta-analysis by Wattakorn Laohapiboolrattana, Priabprat Jansem, Prakit Anukoolwittaya, Duangnapa Roongpiboonsopit, Akarin Hiransuthikul, Thanakit Pongpitakmetha, Sekh Thanprasertsuk, Wanakorn Rattanawong

“…Abstract Background Novel abortive treatments for migraine, ditans and gepants, have promising implications in triptan-insufficient responders with minimal existing comparative data. …”
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Healthcare access, symptom burden, and psychological impact in hypertrophic cardiomyopathy: a multinational patient-driven survey by Emil Tsenov, Jolanda Van der Velden, Matteo Pinciroli, Maurizio Pieroni, Franco Cecchi, Iacopo Olivotto, Niccolò Maurizi

“…The questionnaire included sections on demographics, symptom burden, impact on daily life, medical management, and psychological well-being. Data were analyzed descriptively, with subgroup analyses based on geography, employment, and healthcare access. …”
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The paradox of consumer-level open innovation collaborators in sustainable consumption transformation by Wutthiya Aekthanate Srisathan, Phaninee Naruetharadhol

“…Using partial least squares structural equation modeling (PLS-SEM), primary data were collected from 324 Thai consumers . The findings provide evidence of key dynamics in sustainable consumption. …”
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Cross-cultural adaptation and psychometric evaluation of the factors influencing adherence to the standard precautions scale – Student version (FIASP-SV) for Saudi Arabian nursing... by Salwa Jadid Alanazi, Jung Yeon (Ellie) Park, Fadiyah Jadid Alanazi, Kyeung Mi Oh

“…Using a convenience sample, data were collected from 186 eligible nursing students engaged in patient care across multiple Saudi Arabian universities via an online Qualtrics survey from November 2023 to April 2024. …”
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Long-read sequencing reveals novel isoform-specific eQTLs and regulatory mechanisms of isoform expression in human B cells by Yuya Nagura, Mihoko Shimada, Ryoji Kuribayashi, Ko Ikemoto, Hiroki Kiyose, Arisa Igarashi, Tadashi Kaname, Motoko Unoki, Akihiro Fujimoto

“…A comparison with GWAS data reveals a higher number of colocalizations between ieQTLs and GWAS findings compared to gene eQTLs. …”
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Tremelimumab plus durvalumab versus sorafenib in first-line treatment of unresectable hepatocellular carcinoma: a cost-effectiveness analysis from the US payer perspective by Bin Li, Shuqiao Cheng, Jian Xiao, Shao Liu, Lanhua Tang

“…Although dual immunotherapy represents a novel treatment option for uHCC, the economic implications of these high-priced drugs require further exploration. …”
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Machine Learning-Based Prediction of Ecosystem-Scale CO₂ Flux Measurements by Jeffrey Uyekawa, John Leland, Darby Bergl, Yujie Liu, Andrew D. Richardson, Benjamin Lucas

“…The model showed excellent performance testing on sites that are ecologically similar to other sites (the Mid Atlantic, New England, and the Rocky Mountains), but poorer performance at sites with fewer ecological similarities to other sites in the data (Pacific Northwest, Florida, and Puerto Rico). …”
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Gaussian process latent variable models-ANN based method for automatic features selection and dimensionality reduction for control of EMG-driven systems by Maham Nayab, Asim Waris, Muhammad Jawad Khan, Dokhyl AlQahtani, Ahmed Imran, Syed Omer Gilani, Umer Hameed Shah

“…This approach aims to improve the classification accuracy of EMG signals while substantially reducing computational costs, offering valuable implications for all EMG-related processes on such data. …”
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Dietary patterns and cardiovascular diseases among Chinese high-risk population aged 35 years and older: A 6-year cohort study by Shanshan Chen, Shiyun Hu, Sijie Shen, Jialin Zhang, Xiaohui Xu, Ming Yu, Yu Xia, Qiang Cai, Wei Yu, Anni Lu, Ziqi Mia Li, Rasika Gunarathne, Jun Lu

“…A total of 28,747 high-risk participants in China PEACE in Zhejiang Province from 2014 to 2019 were included in the analysis Dietary data were obtained using the Food Frequency Questionnaire, and dietary patterns were extracted through factor analysis. …”
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Predictors of lipoprotein(a) variability in clinical practice and their impact on cardiovascular risk by Hyung Joon Joo, Seung Gyu Yun, Jae Hyoung Park, Soon Jun Hong, Cheol Woong Yu, Seung Yong Shin, Eung Ju Kim

“…Methods This retrospective multicenter observational study was conducted using data from three tertiary university hospitals in Korea. …”
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Adoption of green inbound logistics practices: the role of internal environmental communication and organizational environmental governance by Sheila Namagembe, Shamim Nantumbwe, Wilson Tusiime, Robert Kalema, George Kalikwani, Rashida Nampijja

“…An actual sample size of 105 public sector firms in the central procuring and disposing entities category was used. The data were analyzed using the Statistical Package for the Social Sciences (SPSS), SMART PLS version 4.0.1.8 and AMOS SPSS v26. …”
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A Narrative Review of Molecular, Immunohistochemical and In-Situ Techniques in Dermatopathology by J. A. Gabriel, N. Weerasinghe, P. Balachandran, R. Salih, G. E. Orchard

“…Together, these molecular techniques have laid the groundwork for targeted therapies and precision medicine in dermatology, with implications for improved diagnostics and treatment outcomes. …”
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Geology, Archaeology, and Historical Studies of the Late 16th Century Plinian Eruption of Raung Volcano: A Potential Case for Disaster Geotourism in Ijen UNESCO Global Geopark, Eas... by Firman Sauqi Nur Sabila, Mirzam Abdurrachman, Asep Saepuloh, Idham Andri Kurniawan, Abdillah Baraas, Dwi Fitri Yudiantoro, Hery Kusdaryanto

“…This research aims to substantiate Raung as the likely source of the major eruption by integrating geological, archaeological, and historical data. This study synthesizes current findings and explores ongoing debates surrounding historical volcanic activities. …”
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Real-life clinical sensitivity of SARS-CoV-2 RT-PCR test in symptomatic patients. by Elisa Kortela, Vesa Kirjavainen, Maarit J Ahava, Suvi T Jokiranta, Anna But, Anna Lindahl, Anu E Jääskeläinen, Annemarjut J Jääskeläinen, Asko Järvinen, Pia Jokela, Hannimari Kallio-Kokko, Raisa Loginov, Laura Mannonen, Eeva Ruotsalainen, Tarja Sironen, Olli Vapalahti, Maija Lappalainen, Hanna-Riikka Kreivi, Hanna Jarva, Satu Kurkela, Eliisa Kekäläinen

“…Adults who were clinically suspected of SARS-CoV-2 infection and underwent SARS-CoV-2 RT-PCR testing, with sufficient data in their medical records for grading of clinical suspicion were eligible. …”
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Factors influencing UK arthroplasty surgeons' decision‐making between total and medial unicompartmental knee surgery: A vignette‐based behavioural experiment by Martine Nurek, Omar Musbahi, Martinique Vella Baldacchino, Robert Hamm, Caroline B. Hing, Justin Cobb, Olga Kostopoulou, UNITES Consortium

“…Deciding which surgery to perform is complex and ill‐defined, yet it has important implications for patients and the health service. The study aimed to identify clinical and surgeon factors predicting surgeons' preferences. …”
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