Exploring barriers and drivers to a modified WHO safe childbirth checklist implementation in three West African countries: a qualitative study using the updated consolidated framew... by Kadidiatou Raïssa Kourouma, Kadidiatou Raïssa Kourouma, Wambi Maurice Evariste Yaméogo, Wambi Maurice Evariste Yaméogo, Daouda Doukouré, Daouda Doukouré, Alpha Oumar Sall, Marie Laurette Agbré Yacé, Marie Laurette Agbré Yacé, Tiéba Millogo, Tiéba Millogo, Mamadou Diouldé Baldé, Issaka Tiembré, Alexandre Delamou, Séni Kouanda, Séni Kouanda

“…The mSCC was implemented in these hospitals along with training and coaching. Data was analyzed using thematic analysis, guided by the updated CFIR framework. …”
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IMB-XMA0038, a new inhibitor targeting aspartate-semialdehyde dehydrogenase of Mycobacterium tuberculosis by Xiao Wang, Ruifang Yang, Sihan Liu, Yan Guan, Chunling Xiao, Chuanyou Li, Jianzhou Meng, Yu Pang, Yishuang Liu

“…There is an urgent need to develop effective anti-TB drugs with novel mechanisms of action. …”
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Non-invasive identification of TKI-resistant NSCLC: a multi-model AI approach for predicting EGFR/TP53 co-mutations by Jiayi Li, Renjie Xu, Dan Wang, Zhanlue Liang, Yangqian Li, Qinglan Wang, Lingfeng Bi, Yawen Qi, Yaojie Zhou, Weimin Li

“…Results In our cohort of 2171 patients (1,153 males, 1,018 females; median age 60 years), single-dimensional models were developed using data from 1,055 eligible patients. …”
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Molecular landscape of the overlap between Alzheimer’s disease and somatic insulin-related diseases by I. Hyun Ruisch, Joanna Widomska, Ward De Witte, Nina R. Mota, Giuseppe Fanelli, Veerle Van Gils, Willemijn J. Jansen, Stephanie J. B. Vos, Abel Fóthi, Csaba Barta, Simone Berkel, Kazi A. Alam, Aurora Martinez, Jan Haavik, Aet O’Leary, David Slattery, Mairéad Sullivan, Jeffrey Glennon, Jan K. Buitelaar, Janita Bralten, Barbara Franke, Geert Poelmans

“…Subsequently, using (additional) GWAS data, we conducted shared genetic etiology analyses between AD and SID, on the one hand, and blood and cerebrospinal fluid (CSF) metabolite levels on the other hand. …”
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急性缺血性卒中院前延迟风险预测模型的构建及评价 Construction and Evaluation of Pre-Hospital Delay Risk Prediction Model for Acute Ischemic Stroke by 倪佃丽1，陈晓兵1，张广慧2，彭庆荣1 (NI Dianli1, CHEN Xiaobing1, ZHANG Guanghui2, PENG Qingrong1 )

“…Based on pre-hospital delay conditions, the model group was further divided into the non-delayed (<3.5 h) group and the delayed (≥3.5 h) group. The data from the model group was used to establish a nomogram model, and the data from the internal validation group was used to assess the model’s generalization performance. …”
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Validity and Reliability of a Mobile Device Application for Assessing Motor Performance in the 30-Second Sit-to-Stand Test by Eduardo Candido Veloso Ferreira, Amelia Pasqual Marques, Szymon Kulis, Jan Gajewski, Anderson Antunes da Costa Moraes, Manuela Brito Duarte, Gizele Cristina da Silva Almeida, Enzo Gabriel da Rocha Santos, Gustavo Henrique Lima Pinto, Andre Dos Santos Cabral, Givago da Silva Souza, Anselmo De Athayde Costa E Silva, Bianca Callegari

“…The motor behavior of the CoM was subsequently observed during task execution. Data were processed offline using routines developed for MatLab software, focusing on the longitudinal axis and describing the event cycles. …”
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Radiogenomic method combining DNA methylation profiles and magnetic resonance imaging radiomics predicts patient prognosis in skull base chordoma by Xiaoyu Deng, Peiran Li, Kaibing Tian, Fan Zhang, Yumeng Yan, Yanghua Fan, Zhen Wu, Junting Zhang, Jiang Du, Wei Chen, Liang Wang

“…HLG patients had higher progression-free survival times than LLG patients. Combined analysis with external single-cell RNA-seq data revealed higher tumor cell proportions and lower natural killer cell proportions in the HLG than in the LLG. …”
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Functional characterization of seven terpene synthases from Ophiopogon japonicus via engineered Escherichia coli by Wen Xu, Qing Ma, Tong Chen, Haiyan Zhang, Guanglei Ma, Sibongile Mafu, Juan Guo, Xiaohui Fan, Guanghong Cui, Baolong Jin

“…Results. This study developed a rapid expression system for monoterpene and sesquiterpene synthases based on engineered E. coli. …”
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Epigenetic Drift Is Involved in the Efficacy of HBV Vaccination by Francesca Ferraresi, Simona Anticoli, Stefano Salvioli, Chiara Pirazzini, Luciano Calzari, Davide Gentilini, Christian Albano, Reparata Rosa Di Prinzio, Salvatore Zaffina, Rita Carsetti, Paolo Garagnani, Anna Ruggieri, Katarzyna Malgorzata Kwiatkowska

“…These epivariants were detected in epigenome-wide data collected from isolated B cell samples from 41 responders and 30 non-responders (age range 22–62 years) to vaccination against HBV. …”
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Morphometrical and Molecular Characterization of Oesophagostomum columbianum (Chabertiidae: Oesophagostominae) and Haemonchus contortus (Trichostrongylidae: Haemonchinae) Isolated... by Tilak Chandra Nath, Dongmin Lee, Hansol Park, Seongjun Choe, Barakaeli Abdieli Ndosi, Yeseul Kang, Mohammed Mebarek Bia, Chatanun Eamudomkarn, Uday Kumar Mohanta, Kazi Mehetazul Islam, Jamal Uddin Bhuiyan, Hyeong-Kyu Jeon, Keeseon S. Eom

“…This study, for the first time, illustrates the characteristics of O. columbianum and H. contortus in Bangladesh, combining both morphological and molecular data. The universal primer-based polymerase chain reaction (PCR) protocol could be an economical and efficient option for researchers from poor resource settings for precise identification of nematodes. …”
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TB death surveillance and response (TBDSR) - A step towards zero deaths due to TB. Lessons learnt from West Bengal, India by Abhijit Dey, Santosh Kumar Roy, Poulami Basu, Dhrubajyoti Deka, Rajat Basu, Simran Keshri, Bandita Sengupta, Sandip Roy

“…This was the study population. A secondary analysis was done on the routinely collected data from the TBDSR portal. …”
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Improving health-promoting workplaces through interdisciplinary approaches. The example of WISEWORK-C, a cluster of five work and health projects within Horizon-Europe by Deborah De Moortel, Michelle C Turner, Ella Arensman, Alex Binh Vinh Duc Nguyen, Víctor Gonzalez

“…By collaborating on data management and analysis, WISEWORK-C enhances the reproducibility and comparability of findings across countries and sectors—an important step for epidemiological rigor. …”
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Defining criteria for disease activity states in juvenile dermatomyositis based on the Juvenile Dermatomyositis Activity Index by Carine Wouters, Nicolino Ruperto, Maria Trachana, Angelo Ravelli, Veronika Vargová, Troels Herlin, Angela Pistorio, Pavla Dolezalova, Claudia Bracaglia, Alessandro Consolaro, Silvia Rosina, Ana Rebollo-Giménez, Ana Guilaisne Bernard-Medina, Laura Carenini

“…Objectives To develop and validate the cut-offs in the Juvenile DermatoMyositis Activity Index (JDMAI) to distinguish the states of inactive disease (ID), low disease activity (LDA), moderate disease activity (MDA) and high disease activity (HDA) in children with juvenile dermatomyositis (JDM).Methods For cut-off definition, data from 139 patients included in a randomised clinical trial were used. …”
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Healthcare providers' perspectives on the organization of health services to manage people with multiple long-term conditions in primary care settings in Kerala, India: a qualitati... by Thoniparambil Ravindranathanpillai Lekha, Linju Joseph, Linju Joseph, Neethu Vasantha Sasidharan, Athira Krishnan, Justine Davies, Paramjit Gill, Sheila Greenfield, Sivadasanpillai Harikrishnan, Jissa Vinoda Thulaseedharan, Mathew Joseph Valamparampil, Semira Manaseki-Holland, Panniyammakal Jeemon, Panniyammakal Jeemon

“…Complexity in managing MLTCs and their adverse consequences confronts the public healthcare systems in India. However, data from India to understand how to improve capacity to manage multiple chronic conditions are limited. …”
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The mediating role of depression in the association between health-related quality of life and suicidal ideation in adolescents: findings from a longitudinal study by Martina Preisig, Isabelle Häberling, Lukasz Smigielski, Sophie Emery, Noemi Baumgartner, Mona Albermann, Michael Strumberger, Klaus Schmeck, Lars Wöckel, Suzanne Erb, Bruno Rhiner, Brigitte Contin-Waldvogel, Susanne Walitza, Susanne Walitza, Susanne Walitza, Gregor Berger

“…IntroductionAdolescent suicidality is a significant public health issue. To develop effective interventions aimed at preventing suicide in this vulnerable population, it is essential to understand the complex interplay of health-related quality of life, depression and suicidal ideation.MethodsFor this purpose, we analyzed longitudinal data of 250 children and adolescents diagnosed with major depressive disorder (M = 15.7, SD = 1.6, range 8–18 years, 74% females). …”
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Prognostic Utility of the Modified Systemic Inflammation Score for Patients Undergoing Oral Cavity Cancer Surgery by Ku-Hao Fang, Sheng-Wei Lo, Adarsh Kudva, Andrea De Vito, Yuan-Hsiung Tsai, Cheng-Ming Hsu, Geng-He Chang, Ethan I. Huang, Ming-Shao Tsai, Chia-Hsuan Lai, Ming-Hsien Tsai, Chun-Ta Liao, Chung-Jan Kang, Yao-Te Tsai

“…Methods: We retrospectively reviewed data from 320 OCSCC patients who underwent curative surgery between 2007 and 2017. …”
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Vulvovaginal candidiasis: knowledge, practices and occurrence among pregnant women receiving antenatal care in a teaching hospital, Ghana by Florence Shine Edziah, Florence Shine Edziah, Princess Ruhama Acheampong, Philip Apraku Tawiah, Cedric Dzidzor Amengor, Godsway Edem Kpene, Grace Otobea Amponsah, Priscilla Appiah Baffoe, Georgina Korankye, John Gameli Deku

“…The hospital records of these participants were further checked to verify the occurrence of the infection. Data were analyzed using Stata version 16. Analysis to identify associations between outcome variables and risk factors as well as significance level was carried out.ResultsOut of the 336 gestational mothers involved in the study, 27.1% were found to have been diagnosed with candidiasis at the time of the study. …”
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A predictive model for hospital death in cancer patients with acute pulmonary embolism using XGBoost machine learning and SHAP interpretation by Zhen-nan Yuan, Yu-juan Xue, Hai-jun Wang, Shi-ning Qu, Chu-lin Huang, Hao Wang, Hao Zhang, Min-ze Zhang, Xue-zhong Xing

“…A retrospective cohort study was conducted using the MIMIC-IV 2.2 database and external data from the intensive care unit of Cancer hospital, Chinese Academy of Medical Sciences, collected between May 1, 2021, and April 30, 2023. …”
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Multicentre external validation of the Neonatal Healthcare-associated infectiOn Prediction (NeoHoP) score: a retrospective case–control study by Andrew Whitelaw, Michael Sharland, Cecilia Ferreyra, Angela Dramowski, Adrie Bekker, Sithembiso Christopher Velaphi, Daynia Elizabeth Ballot, Trusha Nana, Lizel G Lloyd, Mirjam Maria van Weissenbruch, Birgitta Gleeson, Jeannette Wadula

“…This study aims to validate the Neonatal Healthcare-associated infectiOn Prediction (NeoHoP) score, designed for LMICs, across diverse neonatal populations.Methods Prospective data from three South African neonatal units in the Neonatal Sepsis Observational (NeoOBS) study were analysed. …”
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Individual Choices of Wintering Areas Drive Adult Survival Heterogeneity in a Long‐Lived Seabird by M. Genovart, R. Ramos, J. M. Igual, A. Sanz‐Aguilar, G. Tavecchia, A. Rotger, T. Militão, D. Vicente‐Sastre, B. Garcia‐Urdangarin, R. Pradel, J. González‐Solís, D. Oro

“…Additionally, when utilising geolocators, data become accessible only upon individual recapture, presenting a potential source of bias. …”
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