Caregiver and care team perspectives of caregiver psychological distress and well-being during critical care hospitalization: a qualitative study by Amanda C. Blok, Lauren Gauntlett, Mayank Jayaram, Sarah L. Krein

“…Methods Using a qualitative design, we conducted a directed content analysis of semi-structured interview data collected from 20 family caregivers of Veterans in critical care and 12 care team members at a US Veterans Affairs medical and surgical intensive care unit between October 2020 and July 2021. …”
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Predictive Model for In-Hospital Death in Older Patients with Type 2 Diabetes Mellitus: A Multicenter Retrospective Study in Southwest China by Tang Y, Zhang Z, Yu Y, He Y, Yuan Y, Wu X, Xu Q, Niu J, Wu X, Tan J

“…Model performance was assessed through area under the receiver operating characteristic curve (AUROC) analysis and calibration plots. Clinical utility was evaluated using decision curve analysis (DCA) and clinical impact curve (CIC).Results: The overall in-hospital death rate was 3.19% (556 cases). …”
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Rule with an iron hand: powerful CEOs, influential shareholders and corporate performance in Russia by Marina Zavertiaeva, Tatiana Ershova

“…Findings – Panel data analysis suggests that higher board ownership and tenure may restrict CEO power, which in turn would be beneficial for corporate performance. the authors also see that in companies owned by influential businessmen, CEO power influence on M/B value is more negative, while state ownership does not moderate it. …”
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Impact of the COVID-19 Pandemic on Pediatric Pneumonia Outcomes: A Five-Year Retrospective Cohort Study by Heinige P, Slováková L, Vočková J, Leová LN, Tašková A, Kripnerová K, Prchlík M, Doležalová K

“…About 12% of these children developed severe complications. Our analysis showed a clear increase in the number of complicated cases and surgical interventions over time, especially after COVID-19. …”
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Low-input RNA-seq suggests metabolic specialization underlying morphological heterogeneity in a gut commensal bacterium by Elise Bornet, Gianluca Prezza, Laura Cecchino, Laura Jenniches, Jochen Behrends, Caroline Tawk, Kerwyn Casey Huang, Till Strowig, Jörg Vogel, Lars Barquist, Antoine-Emmanuel Saliba, Alexander J. Westermann

“…Differential expression analysis indicates metabolic specialization associated with morphology. …”
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Dynamic Voltage Balancing Across Series-Connected 10 kV SiC JBS Diodes in Medium Voltage 3L-NPC Power Converter Having Snubberless Series-Connected 10 kV SiC MOSFETs by Sanket Parashar, Nithin Kolli, Raj Kumar Kokkonda, Ajit Kanale, Subhashish Bhattacharya, Bantval Jayant Baliga

“…This article provides simplified steps for the design and analysis of the <inline-formula><tex-math notation="LaTeX">$RC$</tex-math></inline-formula> snubber in various test benches, validated by experimental data. …”
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Automated on-site broiler live weight estimation through YOLO-based segmentation by Mahmoud Y. Shams, Wael M. Elmessery, Awad Ali Tayoush Oraiath, Ahmed Elbeltagi, Ali Salem, Pankaj Kumar, Tamer M. El-Messery, Tarek Abd El-Hafeez, Mohamed F. Abdelshafie, Gomaa G. Abd El-Wahhab, Ibrahim S. El-Soaly, Abdallah Elshawadfy Elwakeel

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Modeling of molecular weight changes of polysaccharides subjected to irradiation by Li Wang, Peiling Huang, Jianyong Huang, Huamu Xie, Xingyu Liu, Xinyi Liu, Qing Cai, Boon Chin Heng, Yuanli Huang, Qianqian Han, Zigang Ge

“…It was found that the molecular weight of HA decreases inversely with irradiation time or dose (R-squared: 0.71 - 0.96). Based on these data, a quantitative model was developed to predict the molecular weight of HA after irradiation sterilization, and its feasibility was validated through both theoretical analysis and experimental verification. …”
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A searchable atlas of pathogen-sensitive lncRNA networks in human macrophages by Nils Schmerer, Harshavardhan Janga, Michelle Aillaud, Janina Hoffmann, Marina Aznaourova, Sarah Wende, Henrike Steding, Luke D. Halder, Michael Uhl, Fabian Boldt, Thorsten Stiewe, Andrea Nist, Lukas Jerrentrup, Andreas Kirschbaum, Clemens Ruppert, Oliver Rossbach, Evgenia Ntini, Annalisa Marsico, Chanil Valasarajan, Rolf Backofen, Uwe Linne, Soni S. Pullamsetti, Bernd Schmeck, Leon N. Schulte

“…Abstract Long noncoding RNAs (lncRNA) are crucial yet underexplored regulators of human immunity. Here we develop GRADR, a method integrating gradient profiling with RNA-binding proteome analysis, to map the protein interactomes of all expressed RNAs in a single experiment to study mechanisms of lncRNA-mediated regulation of human primary macrophages. …”
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A new ALK inhibitor overcomes resistance to first‐ and second‐generation inhibitors in NSCLC by Yue Lu, Zhenzhen Fan, Su‐Jie Zhu, Xiaoxing Huang, Zhongji Zhuang, Yunzhan Li, Zhou Deng, Lei Gao, Xuehui Hong, Ting Zhang, Li Li, Xihuan Sun, Wei Huang, Jingfang Zhang, Yan Liu, Baoding Zhang, Jie Jiang, Fu Gui, Zheng Wang, Qiyuan Li, Siyang Song, Xin Huang, Qiao Wu, Lanfen Chen, Dawang Zhou, Jianming Zhang, Cai‐Hong Yun, Liang Chen, Xianming Deng

“…Here, we develop XMU‐MP‐5 as a new‐generation ALK inhibitor to overcome crizotinib resistance mutations, including L1196M and G1202R. …”
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STRAIN LOCALIZATION PECULIARITIES AND DISTRIBUTION OF ACOUSTIC EMISSION SOURCES IN ROCK SAMPLES TESTED BY UNIAXIAL COMPRESSION AND EXPOSED TO ELECTRIC PULSES by V. A. Mubassarova, L. M. Bogomolov, A. S. Zakupin, I. A. Panteleev, O. B. Naimark

“…The above conclusions correlate with the statistical model of a solid body with defects which is developed in ICMM [Panteleev et al., 2011, 2012, 2013a].…”
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What are the broader impacts and value from a randomised controlled trial conducted in six public hospital antenatal clinics in Australia? An impact assessment using the Framework... by Peter G Gibson, Kirsten McCaffery, John Attia, Joerg Mattes, Megan E Jensen, Andrew Searles, Paul B Colditz, Shanthi Ann Ramanathan, Vanessa E Murphy, Michael Hensley, Michael Peek, Andrew Bisits, Leonie Kaye Callaway, Helen Barrett, Sean Seeho, Melanie Rao, Elissa Elvidge, Karen McLaughlin, Annelies Robijn, Warwick Giles, Alistair Abbott

“…Data collection was done via document analysis of BLT administrative and research records and review of relevant websites/databases.Results BLT delivered a return on investment of $6.7 million in leveraged grants, fellowships and consultancies and conservatively returned $2.44 for every dollar invested. …”
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Clinical characteristic of isolated thrombocytopenia in patients with bone marrow failure-related germline variants: a retrospective study from a single centre by Nanxi Dong, Jingjie Dong, Chuanao Xin, Peicheng Wang, Yaonan Hong, Rudan Zheng, Zexing Sun, Qi Liu, Yingying Shen, Xiawan Yang, Yiping Shen, Jianping Shen, Baodong Ye, Yuhong Zhou, Dijiong Wu

“…This study compares prognosis and clinical features of isolated thrombocytopenia in patients with ITGV-BMFsand those with classic ITP.Methods The clinical data of patients diagnosed with ITGV-BMFs were retrospectively analyzed and compared with those of patients with classic ITP from August 2018 to February 2024. …”
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Deep learning-driven modality imputation and subregion segmentation to enhance high-grade glioma grading by Jiabin Yu, Qi Liu, Chenjie Xu, Qinli Zhou, Jiajun Xu, Lingying Zhu, Chen Chen, Yahan Zhou, Binggang Xiao, Lin Zheng, Xiaofeng Zhou, Fengming Zhang, Yuhang Ye, Hongmei Mi, Dongping Zhang, Li Yang, Zhiwei Wu, Jiayi Wang, Ming Chen, Zhirui Zhou, Haoyang Wang, Vicky Y. Wang, Enyu Wang, Dong Xu

“…Materials and methods A retrospective analysis was conducted using data from 1,251 patients in the BraTS2021 dataset as the main cohort and 181 clinical cases collected from a medical center between April 2013 and June 2018 (51 years ± 17; 104 males) as the external test set. …”
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Vocalisations as a potential indicator of parturition in C57BL/6J mice by Sara Capas-Peneda, Ana Ferreira, Colin Gilbert, Jan-Bas Prins, Ashley Vanderplank, Giorgio Rosati, Marco Garzola, Ingrid Anna Sofia Olsson, Gabriela Munhoz Morello

“…Despite limitations such as the need for post-event analysis and the focus on a single mouse strain, this study suggests that detecting vocalisations can be a promising basis for developing automated parturition detection. …”
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From Flanders to Portugal: A Portuguese Painter in Pursuit of Prestigious Flemish Painting—Materials and Techniques Compared Through an Analytical Approach by Vanessa Antunes, António Candeias, José Mirão, Sara Valadas, Ana Cardoso, Maria José Francisco, Alexandra Lauw, Marta Manso, Maria Luísa Carvalho

“…Together, these findings reveal that Jorge Afonso’s workshop developed a distinct Portuguese method—rooted in Flemish practices disseminated by Quentin Metsys—yet adapted to local materials and aesthetic priorities.…”
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Transforming Agroindustry in Indonesia: Emerging Digital Technologies for Reducing Food Loss(Chinese and English versions) by Sari Intan KAILAKU, Yandra ARKEMAN, Y Aris PURWANTO, Faqih UDIN, Bahagiawati AMIRHUSIN, Hendri WIJAYA, Nizmah Jatisari HIDAYAH, Irman HERMADI, Verry Surya HENDRAWAN

“…Through these digital technology approaches, Indonesia has the potential to transition towards a proactive, data-enabled agroindustry that minimises losses and environmental footprints. …”
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Tissue Distribution and Proliferation Characteristics of pVA1-like Plasmid After Infection with Vibrio parahaemolyticus in the Pacific White Shrimp Penaeus vannamei by Xingqi SU, Qiang FU, Xupeng LI, Jie KONG, Jiteng TIAN, Baoxiang CAO, Ning LIU, Sheng LUAN, Kun LUO, Xianhong MENG

“…In recent years, as aquaculture scale has expanded, the aquaculture environment has suffered degradation, and diseases have become increasingly prevalent, severely constraining the development of the Chinese shrimp aquaculture industry. …”
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Adjuvant dendritic cell-based immunotherapy in melanoma: insights into immune cell dynamics and clinical evidence from a phase II trial by Jenny Bulgarelli, Claudia Piccinini, Emanuela Scarpi, Giorgia Gentili, Laura Renzi, Silvia Carloni, Francesco Limarzi, Elena Pancisi, Anna Maria Granato, Massimiliano Petrini, Francesco De Rosa, Massimo Guidoboni, Dalila Fanelli, Maria Maddalena Tumedei, Marcella Tazzari, Stefano Baravelli, Ilaria Bronico, Pietro Cortesi, Sara Pignatta, Laura Capelli, Valentina Ancarani, Giovanni Foschi, Livia Turci, Francesca Tauceri, Massimo Framarini, Laura Ridolfi

“…Moreover, additional immune response data suggested increased immune modulation in vaccinated patients, which may reflect a shift in immune dynamics. …”
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Cell‐free epigenomes enhanced fragmentomics‐based model for early detection of lung cancer by Yadong Wang, Qiang Guo, Zhicheng Huang, Liyang Song, Fei Zhao, Tiantian Gu, Zhe Feng, Haibo Wang, Bowen Li, Daoyun Wang, Bin Zhou, Chao Guo, Yuan Xu, Yang Song, Zhibo Zheng, Zhongxing Bing, Haochen Li, Xiaoqing Yu, Ka Luk Fung, Heqing Xu, Jianhong Shi, Meng Chen, Shuai Hong, Haoxuan Jin, Shiyuan Tong, Sibo Zhu, Chen Zhu, Jinlei Song, Jing Liu, Shanqing Li, Hefei Li, Xueguang Sun, Naixin Liang

“…Machine learning algorithms were then employed to integrate the multi‐omics data, aiding in the development of a precise lung cancer detection model. …”
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