CALCULATION OF PERFORMANCE FOR MECHANICAL DEBONING SCREW PRESSES CONSIDERING COUNTERPRESSURE by A. S. Ostroukh, V. A. Abaldova

“…It is shown that the existing calculation methods are developed for a homogeneous medium using Newtonian isothermal models and that their adjustment to experimental data was carried out byintroducing the relevant empirical coefficients. …”
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The Interrelation between Stock Prices and the Exchange Rate in Kazakhstan by G. Zh. Azretbergenova

“…Nevertheless, there are plenty of empirical studies on the interrelation between exchange rates and the stock market in developed and developing countries. This correlation has not been explored in Kazakhstan.   …”
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Effect of fibroblast heterogeneity on prognosis and drug resistance in high-grade serous ovarian cancer by Tingjie Wang, Lingxi Tian, Bing Wei, Jun Li, Cuiyun Zhang, Ruitao Long, Xiaofei Zhu, Yougai Zhang, Bo Wang, Guangbo Tang, Jun Yang, Yongjun Guo

“…We collected and curated 28 HGSOC patients’ single-cell transcriptomic data from five datasets. Then, we developed a novel text-mining-based machine-learning approach to deconstruct the evolutionary patterns of tumor cell functions. …”
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A comprehensive risk model of disulfidoptosis-related lncRNAs predicts prognosis and therapeutic implications in bladder cancer by Zhixiong Zhang, Jinghua Zhong, Muhammad Sarfaraz Iqbal, Zhiwen Zeng, Xiaolu Duan

“…Functional enrichment analysis uncovered their potential involvement in immune-related biological pathways. …”
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Quantitative determination of blended proportions in tobacco formulations using near-infrared spectroscopy and transfer learning by Qinlin Xiao, Qinlin Xiao, Ruifang Gu, Li Li, Jing Wen, Xixiang Zhang, Yi Shen, Yang Liu, Lan Xiao, Qinqin Tang, Jun Yang, Yong He, Juan Yang

“…A partial least squares regression (PLSR) model was first developed using NIRS data from four different tobacco brands, achieving high prediction accuracy on the combined dataset (RMSEP = 1.20%). …”
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Parents' experiences of parenting a child with profound intellectual and multiple disabilities in France: A qualitative study by Marie‐Anastasie Aim, Marie‐Christine Rousseau, Ilyes Hamouda, Any Beltran Anzola, Thierry Billette deVillemeur, Mathieu Milh, Kim Maincent, Katia Lind, Pascal Auquier, Karine Baumstarck, Lionel Dany

“…Method Qualitative semistructured interviews were conducted by telephone with 34 parents of persons with PIMD aged 8–35. The resulting data were analyzed using thematic analysis. Results The analysis highlighted the diversity of activities performed by parents as well as the influence of context on the forms of this parenting work. …”
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The Candida quercitrusa strain Cq-C08 induces plant resistance to root-knot nematodes by Cuihua Lu, Erfeng Li, Rui Liu, Nv Chang, Yuqing Lai, Yue Wu, Weilong Wu, Zhukan Chen, Jian Ling, Jianlong Zhao, Zhenchuan Mao

“…The selection and utilization of novel biological control resources are crucial for managing RKNs diseases.MethodsThis study isolated Candida quercitrusa Cq-C08 from rhizosphere soil, which the efficacy of Cq-C08 against Meloidogyne incognita was investigated through laboratory experiments, pot and plot trials, and analysis of the transcriptomic data from cucumber roots treated with Cq-C08.Results and discussionThis study isolated Candida quercitrusa Cq-C08 from rhizosphere soil, and a series of experiments confirmed that the fermentation broth had a lethal rate of 100% against M. incognita J2s within 12 h and exhibited a significant repellent effect on the nematodes. …”
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Risk factors for multidrug resistance in pulmonary tuberculosis patients with diabetes mellitus by Lianpeng Wu, Lianpeng Wu, Na Chen, Na Chen, Dandan Xia, Dandan Xia, Xiangao Jiang, Xiangao Jiang

“…Further research is needed to develop targeted interventions based on these findings.…”
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Ferroptosis: a novel pharmacological mechanism against multiple myeloma by Jingbo Shi, Yitong Lu, Wenjian Wei, Guodong Ma, Changnian Li, Lulu Li, Yaru Wang, Yan Wang, Ruirong Xu, Siyuan Cui

“…It aims to provide novel insights and strategies for MM research and clinical therapy.MethodsWe systematically retrieved data from PubMed, Web of Science, ScienceDirect, SciFinder, Scopus, and the China National Knowledge Infrastructure (CNKI) spanning database inception to March 2025, followed by taxonomic integrative analysis of NPs’ and antitumor compounds’ echanistic classifications.ResultsNPs and antitumor compounds exert anti-MM effects via ferroptosis modulation, mechanistically mediated through: 1) lipid metabolism reprogramming; 2) ferritinophagy-driven iron homeostasis regulation; 3) Reactive oxygen species (ROS)-mediated oxidative stress potentiation; 4) autophagic activation; 5) Genes and proteins regulation.ConclusionNPs and antitumor compounds demonstrate therapeutic potential against MM through multi-dimensional ferroptosis modulation, yet clinical translation faces two critical hurdles: 1) predominant focus on single-target mechanisms lacking systems pharmacology-level network analysis; 2) overreliance on in vitro models with insufficient clinical validation. …”
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An integrated machine learning and fractional calculus approach to predicting diabetes risk in women by David Amilo, Khadijeh Sadri, Evren Hincal, Muhammad Farman, Kottakkaran Sooppy Nisar, Mohamed Hafez

“…Glucose levels, BMI, blood pressure, and Diabetes Pedigree Function emerged as the most significant predictors across all models. Complementing these data-driven insights, we develop a Caputo fractional-order model that captures the temporal dynamics of glucose-insulin regulation, BMI, and blood pressure. …”
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Apolipoprotein and menopausal status are significant influencing factors for diabetic retinopathy in type II diabetes mellitus women by Xiaoting Pei, Xi Yao, Di Qi, Yingrui Yang, Shuoning Fan, Zhijie Li

“…Data from 2339 T2DM women were collected between January 2018 and June 2022. …”
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Unravelling typology of family life when a parent has heart disease: A qualitative study of families with adolescents by Matilda Holmbom, Hanna Grundström, Frida Andréasson, Camilla Rotvig, Hege Andersen, Camilla Bernild, Tone Merete Norekvål, Selina Kikkenborg Berg, Anna Strömberg

“…Reflexive thematic analysis was used to identify patterns within families. …”
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Association of Left Atrial Function With Mitral Regurgitation: The Atherosclerosis Risk in Communities Study by Chunxiao Zhang, Wendy Wang, Riccardo M. Inciardi, Yuekai Ji, Khaled Shelbaya, Anne Eaton, Alvaro Alonso, Elsayed Z. Soliman, Scott D. Solomon, Amil M. Shah, Lin Yee Chen

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Comparative effectiveness of maintenance doses of opioid agonist treatment among individuals with opioid use disorder: a target trial emulation protocol using a population-based ob... by M Eugenia Socías, Fahmida Homayra, Bohdan Nosyk, Jeong Eun Min, Julie Bruneau, Nikki Bozinoff, Shaun Seaman, P Todd Korthuis, Paxton Bach, Ehsan Karim, Michelle Zanette, Mary Clare Kennedy

“…All data are deidentified, securely stored and accessed in accordance with provincial privacy regulations. …”
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Association between the Fatty Liver Index (FLI) and incident coronary heart disease: insights from a cohort study on the Chinese population by Ying Miao, Ying Miao, Ying Miao, Ying Miao, Ying Miao, Ying Miao, Ying Miao, Yu Wang, Pijun Yan, Pijun Yan, Pijun Yan, Pijun Yan, Pijun Yan, Pijun Yan, Yi Li, Yi Li, Yi Li, Yi Li, Yi Li, Yi Li, Zhuang Chen, Nanwei Tong, Qin Wan, Qin Wan, Qin Wan, Qin Wan, Qin Wan, Qin Wan

“…Comprehensive data collection employed both questionnaires and specialized medical equipment, covering physical measurements, blood pressure, and pertinent biochemical markers. …”
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Time intervals and routes to diagnosis for lung cancer in 10 jurisdictions: cross-sectional study findings from the International Cancer Benchmarking Partnership (ICBP) by David Weller, Usha Menon, Alina Zalounina Falborg, Henry Jensen, Andriana Barisic, Anne Kari Knudsen, Rebecca J Bergin, David H Brewster, Victoria Cairnduff, Eva Grunfeld, Elizabeth Harland, Mats Lambe, Rebecca-Jane Law, Yulan Lin, Martin Malmberg, Donna Turner, Richard D Neal, Victoria White, Samantha Harrison, Irene Reguilon, Peter Vedsted, Anna Gavin, John Butler, Odd Terje Brustugun, Oliver Bucher, Jatinderpal Kalsi

“…The proportion of patients diagnosed following presentation to the PCP ranged from 35% to 75%.Conclusion There are differences between jurisdictions in interval to treatment, which are magnified in patients with lung cancer who wait the longest. The data could help jurisdictions develop more focused lung cancer policy and targeted clinical initiatives. …”
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Population-Based Real-World Outcomes of Post-Operative Adjuvant Brain Cavity Radiotherapy Versus Observation by Zhang Hao (Jim) Li, Linden Lechner, Jennifer Wang, Nan Hui (Susan) Yao, Andrew Lee, Serge Makarenko, Mostafa Fatehi, Herve H. F. Choi, Ermias Gete, Fred Hsu, Waseem Sharieff, Shrinivas Rathod, Hannah Carolan, Jessica Chan, Roy Ma, Alan Nichol, Thi Nghiem, Justin Oh

“…Post-operative SRT outcomes based on real-world population data are consistent with the data from clinical trials and support the established guidelines. …”
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Decadal variations in the driving factors of increasing water-use efficiency in China's terrestrial ecosystems from 2000 to 2022 by Zhongen Niu, Honglin He, Ying Zhao, Bin Wang, Lili Feng, Yan Lv, Mengyu Zhang, Jiayi Fan, Zhihao Li

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Selection of an Optimal Metabolic Model for Accurately Predicting the Hepatic Clearance of Albumin-Binding-Sensitive Drugs by Ren-Jong Liang, Shu-Hao Hsu, Hsueh-Tien Chen, Wan-Han Chen, Han-Yu Fu, Hsin-Ying Chen, Hong-Jaan Wang, Sung-Ling Tang

“…The current study extends this strategy by verifying the accuracy of the selected models using ex situ experimental data, particularly for drugs whose model choices are influenced by protein binding. …”
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Unveiling the interplay among skin microbiota, cytokines, and T2DM: an insightful Mendelian randomization study by Zhe Zhang, Chunyu Jiang, Yi-qi Xing, Tianke Yang, Linxuan Zou, Zhuqiang Jia, Lin Zhao, Xin Han, Xueling Qu, Zhen Zhang, Junwei Zong, Shouyu Wang

“…Method This study incorporated data from the GWAS database on the skin microbiome, 91 types of inflammatory cytokines, and T2DM. …”
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